EA201070274A1 - Трициклическое аминное соединение - Google Patents

Трициклическое аминное соединение

Info

Publication number
EA201070274A1
EA201070274A1 EA201070274A EA201070274A EA201070274A1 EA 201070274 A1 EA201070274 A1 EA 201070274A1 EA 201070274 A EA201070274 A EA 201070274A EA 201070274 A EA201070274 A EA 201070274A EA 201070274 A1 EA201070274 A1 EA 201070274A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hydrogen atom
alkyl group
amine compound
group
tricyclic amine
Prior art date
Application number
EA201070274A
Other languages
English (en)
Inventor
Йохей Амано
Масаюки Ногути
Коити Судо
Original Assignee
Рисерч Фаундейшн Ицуу Лэборетери
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рисерч Фаундейшн Ицуу Лэборетери filed Critical Рисерч Фаундейшн Ицуу Лэборетери
Publication of EA201070274A1 publication Critical patent/EA201070274A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/28—Phenalenes; Hydrogenated phenalenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/34—Benzoheptalenes; Hydrogenated benzoheptalenes

Abstract

Соединение, представленное следующей общей формулой (I):где Rпредставляет атом водорода или Cалкильную группу, А и В представляют -(СН)-, -(СН)- или -(CH)- , X представляет -N(R)- (Rпредставляет атом водорода или Cалкильную группу), -СО-, -C(=N-R)- (Rпредставляет атом водорода или Cалкильную группу) или -C(=C(R)(R))- (Rи Rнезависимо представляют атом водорода или Cалкильную группу) и Ar представляет арилдиильную группу или гетероарилдиильную группу, которое обладает действием по регулированию физиологической активности ретиноидов и применяется в качестве активного ингредиента лекарственного средства.
EA201070274A 2007-08-15 2008-08-14 Трициклическое аминное соединение EA201070274A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007211651 2007-08-15
PCT/JP2008/064577 WO2009022722A1 (ja) 2007-08-15 2008-08-14 ３環系アミン化合物

Publications (1)

Publication Number Publication Date
EA201070274A1 true EA201070274A1 (ru) 2010-10-29

Family

ID=40350775

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070274A EA201070274A1 (ru) 2007-08-15 2008-08-14 Трициклическое аминное соединение

Country Status (9)

Country Link
US (1) US8143260B2 (ru)
EP (1) EP2189440A1 (ru)
JP (1) JP5399249B2 (ru)
CN (1) CN101821229B (ru)
AU (1) AU2008287819A1 (ru)
CA (1) CA2695984A1 (ru)
EA (1) EA201070274A1 (ru)
TW (1) TW200927709A (ru)
WO (1) WO2009022722A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2861268T3 (es) 2011-09-20 2021-10-06 Basf Se Moduladores de bajo peso molecular del receptor de mentol frío TRPM8 y su uso
WO2020157069A1 (en) * 2019-01-28 2020-08-06 NodThera Limited Amino heterocyclic compounds and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6176440A (ja) 1984-09-19 1986-04-18 Koichi Shiyudo 安息香酸誘導体
JPS6122047A (ja) 1984-07-07 1986-01-30 Koichi Shiyudo 安息香酸誘導体
US5442124A (en) 1989-06-30 1995-08-15 Firmenich Sa Process for the preparation of novel aromatic compounds
EP0405427B1 (fr) * 1989-06-30 1995-03-29 Firmenich Sa Nouveaux composés aromatiques, leur procédé de préparation et leur utilisation à titre d'ingrédients parfumants
US5185318A (en) 1989-06-30 1993-02-09 Firmenich S.A. Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients
JP3964478B2 (ja) 1995-06-30 2007-08-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬
JP3865829B2 (ja) 1995-09-21 2007-01-10 株式会社医薬分子設計研究所 レチノイド作用増強性化合物
US5929069A (en) 1995-09-21 1999-07-27 Institute Of Medicinal Molecular Design, Inc. Compounds activating pharmacological effects of retinoids
WO1999024415A1 (fr) 1997-11-12 1999-05-20 Institute Of Medicinal Molecular Design, Inc. Agonistes du recepteur du retinoide
JP3044348B1 (ja) 1998-12-28 2000-05-22 株式会社大阪冷研 プリフォ―ム口首部の内径規制用コア

Also Published As

Publication number Publication date
JP5399249B2 (ja) 2014-01-29
EP2189440A1 (en) 2010-05-26
CN101821229B (zh) 2013-06-05
AU2008287819A1 (en) 2009-02-19
CA2695984A1 (en) 2009-02-19
CN101821229A (zh) 2010-09-01
JPWO2009022722A1 (ja) 2010-11-18
TW200927709A (en) 2009-07-01
US8143260B2 (en) 2012-03-27
US20110288299A1 (en) 2011-11-24
WO2009022722A1 (ja) 2009-02-19

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