WO2009008391A1 - 生体摂取物微粒子の製造方法、生体摂取物微粒子及びこれを含有する分散体、医薬組成物 - Google Patents
生体摂取物微粒子の製造方法、生体摂取物微粒子及びこれを含有する分散体、医薬組成物 Download PDFInfo
- Publication number
- WO2009008391A1 WO2009008391A1 PCT/JP2008/062234 JP2008062234W WO2009008391A1 WO 2009008391 A1 WO2009008391 A1 WO 2009008391A1 JP 2008062234 W JP2008062234 W JP 2008062234W WO 2009008391 A1 WO2009008391 A1 WO 2009008391A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microparticles
- ingested
- solvent
- thin film
- approachable
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/668,021 US8623415B2 (en) | 2007-07-06 | 2008-07-04 | Method for producing biologically ingestible microparticles, biologically ingestible microparticles, and dispersion and pharmaceutical composition containing the same |
CN200880104295XA CN101784258B (zh) | 2007-07-06 | 2008-07-04 | 生物摄取物微粒子及其制造方法、分散体、医药组成物 |
JP2009503347A JP4419157B2 (ja) | 2007-07-06 | 2008-07-04 | 生体摂取物微粒子の製造方法 |
EP08790914.9A EP2177210B1 (en) | 2007-07-06 | 2008-07-04 | Method of producing microparticles to be ingested into the body, microparticles to be ingested into the body and dispersion and medicinal composition containing the same |
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007179102 | 2007-07-06 | ||
JP2007-179098 | 2007-07-06 | ||
JP2007-179102 | 2007-07-06 | ||
JP2007179104 | 2007-07-06 | ||
JP2007179098 | 2007-07-06 | ||
JP2007-179104 | 2007-07-06 | ||
JP2007-180349 | 2007-07-09 | ||
JP2007180349 | 2007-07-09 | ||
JP2007203850 | 2007-08-06 | ||
JP2007-203850 | 2007-08-06 | ||
JP2007-214821 | 2007-08-21 | ||
JP2007214821 | 2007-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009008391A1 true WO2009008391A1 (ja) | 2009-01-15 |
Family
ID=40228562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/062234 WO2009008391A1 (ja) | 2007-07-06 | 2008-07-04 | 生体摂取物微粒子の製造方法、生体摂取物微粒子及びこれを含有する分散体、医薬組成物 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8623415B2 (ja) |
EP (1) | EP2177210B1 (ja) |
JP (1) | JP4419157B2 (ja) |
CN (1) | CN101784258B (ja) |
WO (1) | WO2009008391A1 (ja) |
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JPWO2012165000A1 (ja) * | 2011-05-28 | 2015-02-23 | エム・テクニック株式会社 | 強制薄膜式流体処理装置を用いた処理物の付着防止方法 |
KR20170031082A (ko) | 2014-07-14 | 2017-03-20 | 엠. 테크닉 가부시키가이샤 | 단결정 산화아연 나노 입자의 제조 방법 |
WO2017221314A1 (ja) * | 2016-06-20 | 2017-12-28 | エム・テクニック株式会社 | 有機物微粒子の製造方法 |
WO2018038267A1 (ja) * | 2016-08-26 | 2018-03-01 | 株式会社 先端医療開発 | ポリラクチドグリコライド共重合体ナノ粒子及びポリラクチドグリコライド共重合体ナノ粒子の製造方法 |
US10003393B2 (en) | 2014-12-16 | 2018-06-19 | Blackberry Limited | Method and apparatus for antenna selection |
CN109091390A (zh) * | 2018-08-28 | 2018-12-28 | 陈科 | 便于泄放药液的电式煎药壶 |
JP2022136376A (ja) * | 2021-03-08 | 2022-09-21 | ユーシービージャパン株式会社 | レベチラセタムを有効成分とする注射用製剤 |
US11633359B2 (en) | 2014-12-15 | 2023-04-25 | M. Technique Co., Ltd. | Method for producing organic material microparticles, and method for modifying organic material microparticles |
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---|---|---|---|---|
JP2009082902A (ja) * | 2007-07-06 | 2009-04-23 | M Technique Co Ltd | 強制超薄膜回転式処理法を用いたナノ粒子の製造方法 |
US8609035B2 (en) * | 2008-11-25 | 2013-12-17 | M. Technique Co., Ltd. | Fluid processing apparatus and processing method |
KR101848716B1 (ko) * | 2010-02-03 | 2018-04-13 | 엠. 테크닉 가부시키가이샤 | 나노 미립자의 제조 방법 |
EP2540390B1 (en) * | 2010-02-26 | 2019-03-27 | M Technique Co., Ltd. | Fluid treatment device and treatment method |
CN103648634B (zh) * | 2011-07-13 | 2016-05-18 | M技术株式会社 | 控制了微晶粒径的微粒的制造方法 |
CN104284715A (zh) * | 2012-05-01 | 2015-01-14 | M技术株式会社 | 微粒的制造方法 |
KR101988238B1 (ko) * | 2012-09-12 | 2019-06-12 | 엠. 테크닉 가부시키가이샤 | 니켈 미립자의 제조 방법 |
CN108469465B (zh) * | 2018-03-19 | 2020-11-03 | 西北大学 | 一种用于激光剥蚀的载样装置 |
JP2019200291A (ja) * | 2018-05-16 | 2019-11-21 | 京セラドキュメントソリューションズ株式会社 | 画像処理装置 |
CN113102032A (zh) * | 2021-04-14 | 2021-07-13 | 皇甫现超 | 一种应用于颗粒物药材研磨设备 |
Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04295420A (ja) | 1991-01-25 | 1992-10-20 | Sterling Winthrop Inc | 表面変性薬物微小粒子 |
JPH06227967A (ja) | 1992-12-04 | 1994-08-16 | Sterling Winthrop Inc | ナノ粒子を含む組成物及びその製造方法 |
JPH07277729A (ja) | 1994-04-14 | 1995-10-24 | Kao Corp | 硫酸バリウムの製造方法 |
JP2002538227A (ja) * | 1999-03-10 | 2002-11-12 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 微結晶生成物を生成するための結晶化方法 |
JP2003159696A (ja) | 2001-11-27 | 2003-06-03 | Starlite Co Ltd | 化学マイクロデバイス |
JP2003210957A (ja) | 2002-01-18 | 2003-07-29 | Fuji Photo Film Co Ltd | マイクロミキサー |
JP2004049957A (ja) | 2002-07-16 | 2004-02-19 | M Technique Co Ltd | 分散乳化装置及び分散乳化方法 |
JP2004174297A (ja) * | 2002-11-25 | 2004-06-24 | M Technique Co Ltd | 微細化装置付脱気機及び微細化による脱気方法 |
JP2005270745A (ja) | 2004-03-23 | 2005-10-06 | Kiyoshi Yatsui | 超微粒子の製造方法およびその製造装置 |
JP2006028108A (ja) * | 2004-07-20 | 2006-02-02 | Nippon Tenganyaku Kenkyusho:Kk | トラニラストまたは薬理学的に許容される塩を含有する懸濁性医薬組成物 |
JP2006089386A (ja) * | 2004-09-21 | 2006-04-06 | Nippon Tenganyaku Kenkyusho:Kk | ステロイドまたはステロイド誘導体を含有する懸濁性医薬組成物 |
JP2006104193A (ja) | 2004-09-07 | 2006-04-20 | Mitsubishi Chemicals Corp | 微粒子化された物質の製造方法および微粒子化された物質 |
JP2007077061A (ja) | 2005-09-14 | 2007-03-29 | Nippon Tenganyaku Kenkyusho:Kk | ピレノキシンまたは薬理学的に許容される塩を含有する懸濁性医薬組成物 |
JP2007230957A (ja) * | 2006-03-03 | 2007-09-13 | Nippon Tenganyaku Kenkyusho:Kk | トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5919724B2 (ja) | 1980-08-27 | 1984-05-08 | 住友化学工業株式会社 | 回転円盤脱揮押出方法およびその装置 |
US20040028582A1 (en) * | 1999-03-10 | 2004-02-12 | Smithkline Beecham Corporation | Crystallization process for producing fine crystal products |
CN1373083A (zh) * | 2001-03-07 | 2002-10-09 | 鞍山钢铁学院 | 一种尺寸可控的纳米粉体制备方法 |
SG126676A1 (en) * | 2001-05-09 | 2007-01-30 | Nanomaterials Tech Pte Ltd | Process for the controlled production of organic particles |
GB2377661B (en) * | 2001-07-20 | 2005-04-20 | Univ Newcastle | Methods of manufacturing particles |
KR20050037477A (ko) * | 2001-10-17 | 2005-04-22 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 로터-스테이터 장치와 입자 생성을 위한 방법 |
DE60307741T2 (de) * | 2002-07-16 | 2007-08-23 | M Technique Co., Ltd., Izumi | Verfahren und Verarbeitungsgerät for Flüssigkeiten |
JP3864131B2 (ja) | 2002-11-05 | 2006-12-27 | エム・テクニック株式会社 | 磨砕機 |
US20060147535A1 (en) * | 2003-04-16 | 2006-07-06 | Poongunran Muthukumaran | Methods for and compositions of anticancer medicaments |
US7125527B2 (en) * | 2003-09-05 | 2006-10-24 | Kinetichem, Inc. | Methods of operating surface reactors and reactors employing such methods |
JP4252993B2 (ja) * | 2005-05-12 | 2009-04-08 | 株式会社荏原製作所 | 混合器及び反応装置 |
JP2006341232A (ja) * | 2005-06-10 | 2006-12-21 | Canon Inc | 流体処理装置および流体処理方法 |
-
2008
- 2008-07-04 EP EP08790914.9A patent/EP2177210B1/en active Active
- 2008-07-04 WO PCT/JP2008/062234 patent/WO2009008391A1/ja active Application Filing
- 2008-07-04 CN CN200880104295XA patent/CN101784258B/zh active Active
- 2008-07-04 JP JP2009503347A patent/JP4419157B2/ja active Active
- 2008-07-04 US US12/668,021 patent/US8623415B2/en active Active
Patent Citations (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04295420A (ja) | 1991-01-25 | 1992-10-20 | Sterling Winthrop Inc | 表面変性薬物微小粒子 |
JPH06227967A (ja) | 1992-12-04 | 1994-08-16 | Sterling Winthrop Inc | ナノ粒子を含む組成物及びその製造方法 |
JPH07277729A (ja) | 1994-04-14 | 1995-10-24 | Kao Corp | 硫酸バリウムの製造方法 |
JP2002538227A (ja) * | 1999-03-10 | 2002-11-12 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 微結晶生成物を生成するための結晶化方法 |
JP2003159696A (ja) | 2001-11-27 | 2003-06-03 | Starlite Co Ltd | 化学マイクロデバイス |
JP2003210957A (ja) | 2002-01-18 | 2003-07-29 | Fuji Photo Film Co Ltd | マイクロミキサー |
JP2004049957A (ja) | 2002-07-16 | 2004-02-19 | M Technique Co Ltd | 分散乳化装置及び分散乳化方法 |
JP2004174297A (ja) * | 2002-11-25 | 2004-06-24 | M Technique Co Ltd | 微細化装置付脱気機及び微細化による脱気方法 |
JP2005270745A (ja) | 2004-03-23 | 2005-10-06 | Kiyoshi Yatsui | 超微粒子の製造方法およびその製造装置 |
JP2006028108A (ja) * | 2004-07-20 | 2006-02-02 | Nippon Tenganyaku Kenkyusho:Kk | トラニラストまたは薬理学的に許容される塩を含有する懸濁性医薬組成物 |
JP2006104193A (ja) | 2004-09-07 | 2006-04-20 | Mitsubishi Chemicals Corp | 微粒子化された物質の製造方法および微粒子化された物質 |
JP2006089386A (ja) * | 2004-09-21 | 2006-04-06 | Nippon Tenganyaku Kenkyusho:Kk | ステロイドまたはステロイド誘導体を含有する懸濁性医薬組成物 |
JP2007077061A (ja) | 2005-09-14 | 2007-03-29 | Nippon Tenganyaku Kenkyusho:Kk | ピレノキシンまたは薬理学的に許容される塩を含有する懸濁性医薬組成物 |
JP2007230957A (ja) * | 2006-03-03 | 2007-09-13 | Nippon Tenganyaku Kenkyusho:Kk | トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物 |
Non-Patent Citations (4)
Title |
---|
"Martindale, The Extra Pharmacopoeia", 1989, THE PHARMACEUTICAL PRESS |
"Nanotechnology Handbook, Part I, Creation", 2003, OHMSHA LTD. |
INT J. PHARM, vol. 125, 1995, pages 309 - 313 |
INT J. PHARM, vol. 125, 1995, pages 91 - 97 |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2012165000A1 (ja) * | 2011-05-28 | 2015-02-23 | エム・テクニック株式会社 | 強制薄膜式流体処理装置を用いた処理物の付着防止方法 |
KR20170031082A (ko) | 2014-07-14 | 2017-03-20 | 엠. 테크닉 가부시키가이샤 | 단결정 산화아연 나노 입자의 제조 방법 |
US10364508B2 (en) | 2014-07-14 | 2019-07-30 | M. Technique Co., Ltd. | Method for producing single crystalline zinc oxide nanoparticles |
US11633359B2 (en) | 2014-12-15 | 2023-04-25 | M. Technique Co., Ltd. | Method for producing organic material microparticles, and method for modifying organic material microparticles |
US10003393B2 (en) | 2014-12-16 | 2018-06-19 | Blackberry Limited | Method and apparatus for antenna selection |
WO2017221314A1 (ja) * | 2016-06-20 | 2017-12-28 | エム・テクニック株式会社 | 有機物微粒子の製造方法 |
WO2018038267A1 (ja) * | 2016-08-26 | 2018-03-01 | 株式会社 先端医療開発 | ポリラクチドグリコライド共重合体ナノ粒子及びポリラクチドグリコライド共重合体ナノ粒子の製造方法 |
CN109091390A (zh) * | 2018-08-28 | 2018-12-28 | 陈科 | 便于泄放药液的电式煎药壶 |
JP2022136376A (ja) * | 2021-03-08 | 2022-09-21 | ユーシービージャパン株式会社 | レベチラセタムを有効成分とする注射用製剤 |
Also Published As
Publication number | Publication date |
---|---|
EP2177210A1 (en) | 2010-04-21 |
US8623415B2 (en) | 2014-01-07 |
EP2177210A4 (en) | 2013-01-23 |
JPWO2009008391A1 (ja) | 2010-09-09 |
EP2177210B1 (en) | 2018-08-22 |
CN101784258A (zh) | 2010-07-21 |
US20100322997A1 (en) | 2010-12-23 |
JP4419157B2 (ja) | 2010-02-24 |
CN101784258B (zh) | 2013-07-17 |
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