WO2008123128A1 - アディポネクチン産生促進剤 - Google Patents
アディポネクチン産生促進剤 Download PDFInfo
- Publication number
- WO2008123128A1 WO2008123128A1 PCT/JP2008/055238 JP2008055238W WO2008123128A1 WO 2008123128 A1 WO2008123128 A1 WO 2008123128A1 JP 2008055238 W JP2008055238 W JP 2008055238W WO 2008123128 A1 WO2008123128 A1 WO 2008123128A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- enhancer
- beverage
- food
- adiponectin production
- pharmaceutical composition
- Prior art date
Links
- 102000011690 Adiponectin Human genes 0.000 title abstract 5
- 108010076365 Adiponectin Proteins 0.000 title abstract 5
- 239000003623 enhancer Substances 0.000 title abstract 5
- 235000013361 beverage Nutrition 0.000 abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 208000004930 Fatty Liver Diseases 0.000 abstract 1
- 206010019708 Hepatic steatosis Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 108010013296 Sericins Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000010706 fatty liver disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/66—Proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
本発明は、セリシンを有効成分として含んでなるアディポネクチン産生促進剤、およびそれを含む医薬および飲食品に関する。これらは、肥満に伴う動脈硬化、脂肪肝、糖尿病などのような、血中のアディポネクチン濃度の低下に起因する各種疾病の予防または改善に有効である。本発明よる促進剤、医薬組成物、および飲食品は、アディポネクチンの産生促進効果に優れ、かつ安全性が高く、各種の医薬や飲食品に幅広く応用が期待できる。
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/450,286 US8722614B2 (en) | 2007-03-23 | 2008-03-21 | Adiponectin production enhancer |
EP08722602A EP2127663A4 (en) | 2007-03-23 | 2008-03-21 | ADIPONECTIN PRODUCTION PROMOTER |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007077131A JP2010018522A (ja) | 2007-03-23 | 2007-03-23 | アディポネクチン産生促進剤 |
JP2007-077131 | 2007-03-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008123128A1 true WO2008123128A1 (ja) | 2008-10-16 |
Family
ID=39830625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/055238 WO2008123128A1 (ja) | 2007-03-23 | 2008-03-21 | アディポネクチン産生促進剤 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8722614B2 (ja) |
EP (1) | EP2127663A4 (ja) |
JP (1) | JP2010018522A (ja) |
WO (1) | WO2008123128A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010180149A (ja) * | 2009-02-04 | 2010-08-19 | Lintec Corp | 嚥下補助剤 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101213825B1 (ko) | 2010-07-16 | 2012-12-18 | 서울대학교산학협력단 | 세린을 유효성분으로 함유하는 지방간 질환의 예방 및 치료용 조성물 |
US20140037762A1 (en) * | 2011-02-14 | 2014-02-06 | Toshinori ITOU | Adiponectin production promoter, and medicinal composition, food, drink and feed containing adiponectin production promoter |
US9138455B2 (en) * | 2013-03-15 | 2015-09-22 | Mead Johnson Nutrition Company | Activating adiponectin by casein hydrolysate |
US9668999B2 (en) * | 2014-04-23 | 2017-06-06 | Semi Labs Limited | Method for the treatment of hypercholesterolemia |
WO2020141778A1 (ko) * | 2018-12-31 | 2020-07-09 | (주)엔아이앤팜 | 세리신을 포함하는 지방간 치료, 예방, 또는 완화용 조성물 및 상기 조성물의 제조 방법 |
KR20200083247A (ko) * | 2018-12-31 | 2020-07-08 | (주) 엔아이앤팜 | 세리신을 포함하는 지방간 치료, 예방, 또는 완화용 조성물 및 상기 조성물의 제조 방법 |
JP2021029143A (ja) * | 2019-08-20 | 2021-03-01 | オリザ油化株式会社 | 糖化抑制剤 |
Citations (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01256351A (ja) * | 1988-04-01 | 1989-10-12 | Terumo Corp | 絹蛋白質を用いた食品およびその製造方法 |
JPH10140154A (ja) * | 1996-11-08 | 1998-05-26 | Seiren Co Ltd | 抗酸化剤 |
JPH10265403A (ja) * | 1997-03-24 | 1998-10-06 | Seiren Co Ltd | チロシナーゼ活性阻害剤 |
JP2000184868A (ja) * | 1998-12-21 | 2000-07-04 | Seiren Co Ltd | 飲食品用水 |
JP2000256210A (ja) | 1999-03-04 | 2000-09-19 | Seiren Co Ltd | 大腸ガン予防剤 |
JP2000312568A (ja) | 1999-03-04 | 2000-11-14 | Seiren Co Ltd | 難消化性飲食品添加物及び健康補助剤 |
JP2001354584A (ja) * | 2000-06-14 | 2001-12-25 | Aioi Hakko:Kk | 皮膚癌予防剤 |
JP2002128691A (ja) | 2000-10-24 | 2002-05-09 | National Institute Of Agrobiological Sciences | セリシン含有素材、その製造方法およびその使用方法 |
JP2003231610A (ja) * | 2002-02-05 | 2003-08-19 | Mikimoto Pharmaceut Co Ltd | 乳化組成物 |
JP2004018648A (ja) * | 2002-06-14 | 2004-01-22 | Seiren Co Ltd | 抗酸化剤 |
JP2004244371A (ja) * | 2003-02-14 | 2004-09-02 | Kenji Nakamura | 保湿組成物及びその製造方法 |
JP2006056836A (ja) | 2004-08-20 | 2006-03-02 | Taiyo Kagaku Co Ltd | 脂肪組織特異分泌蛋白産生増強組成物 |
JP2006232787A (ja) * | 2005-02-28 | 2006-09-07 | Seiren Co Ltd | 水溶性シルクタンパク質を含有する含水組成物 |
JP2007031302A (ja) | 2005-07-25 | 2007-02-08 | Noevir Co Ltd | アディポネクチン産生促進剤、及び代謝異常症候群予防剤 |
JP2007077131A (ja) | 2005-09-15 | 2007-03-29 | Shigeharu Kaiho | にがりを使用した歯磨き液の製造法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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KR100478928B1 (ko) | 1996-11-08 | 2005-08-18 | 세이렌가부시끼가이샤 | 세리신또는세리신가수분해물을유효성분으로하는비의약용항산화제,화장품,식품변색방지제,음식물,심근경색치료제,동맥경화치료제,당뇨병치료제,암치료제,또는뇌줄중치료제 |
CN1168493C (zh) | 1999-03-04 | 2004-09-29 | 精炼株式会社 | 功能性口服剂 |
GB0213612D0 (en) * | 2002-06-13 | 2002-07-24 | Novartis Nutrition Ag | Organic compounds |
US20060128797A1 (en) * | 2004-12-15 | 2006-06-15 | Yanming Wang | Method and composition for resuscitation |
-
2007
- 2007-03-23 JP JP2007077131A patent/JP2010018522A/ja active Pending
-
2008
- 2008-03-21 US US12/450,286 patent/US8722614B2/en active Active
- 2008-03-21 EP EP08722602A patent/EP2127663A4/en not_active Ceased
- 2008-03-21 WO PCT/JP2008/055238 patent/WO2008123128A1/ja active Application Filing
Patent Citations (15)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH01256351A (ja) * | 1988-04-01 | 1989-10-12 | Terumo Corp | 絹蛋白質を用いた食品およびその製造方法 |
JPH10140154A (ja) * | 1996-11-08 | 1998-05-26 | Seiren Co Ltd | 抗酸化剤 |
JPH10265403A (ja) * | 1997-03-24 | 1998-10-06 | Seiren Co Ltd | チロシナーゼ活性阻害剤 |
JP2000184868A (ja) * | 1998-12-21 | 2000-07-04 | Seiren Co Ltd | 飲食品用水 |
JP2000256210A (ja) | 1999-03-04 | 2000-09-19 | Seiren Co Ltd | 大腸ガン予防剤 |
JP2000312568A (ja) | 1999-03-04 | 2000-11-14 | Seiren Co Ltd | 難消化性飲食品添加物及び健康補助剤 |
JP2001354584A (ja) * | 2000-06-14 | 2001-12-25 | Aioi Hakko:Kk | 皮膚癌予防剤 |
JP2002128691A (ja) | 2000-10-24 | 2002-05-09 | National Institute Of Agrobiological Sciences | セリシン含有素材、その製造方法およびその使用方法 |
JP2003231610A (ja) * | 2002-02-05 | 2003-08-19 | Mikimoto Pharmaceut Co Ltd | 乳化組成物 |
JP2004018648A (ja) * | 2002-06-14 | 2004-01-22 | Seiren Co Ltd | 抗酸化剤 |
JP2004244371A (ja) * | 2003-02-14 | 2004-09-02 | Kenji Nakamura | 保湿組成物及びその製造方法 |
JP2006056836A (ja) | 2004-08-20 | 2006-03-02 | Taiyo Kagaku Co Ltd | 脂肪組織特異分泌蛋白産生増強組成物 |
JP2006232787A (ja) * | 2005-02-28 | 2006-09-07 | Seiren Co Ltd | 水溶性シルクタンパク質を含有する含水組成物 |
JP2007031302A (ja) | 2005-07-25 | 2007-02-08 | Noevir Co Ltd | アディポネクチン産生促進剤、及び代謝異常症候群予防剤 |
JP2007077131A (ja) | 2005-09-15 | 2007-03-29 | Shigeharu Kaiho | にがりを使用した歯磨き液の製造法 |
Non-Patent Citations (17)
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See also references of EP2127663A4 |
TADOKOR T. ET AL.: "Shokuhin Miriyo Shigen to Shiteno Silk no Oyo o Mezasu - Silk Tanpakushitsu no Shokuhin Kinosei o Akiraka ni suru Eiyogakuteki Kenkyu -", YASAN, vol. 55, January 2006 (2006-01-01), pages 11 - 14, XP003021991 * |
ZHAORIGETU S. ET AL.: "Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-alpha", ONCOLOGY REPORTS, vol. 10, no. 3, 2003, pages 537 - 543, XP008113880 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010180149A (ja) * | 2009-02-04 | 2010-08-19 | Lintec Corp | 嚥下補助剤 |
Also Published As
Publication number | Publication date |
---|---|
US8722614B2 (en) | 2014-05-13 |
EP2127663A1 (en) | 2009-12-02 |
US20100035810A1 (en) | 2010-02-11 |
JP2010018522A (ja) | 2010-01-28 |
EP2127663A4 (en) | 2011-04-13 |
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