WO2008101486A3 - Beschichtetes expandierbares system - Google Patents

Beschichtetes expandierbares system Download PDF

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Publication number
WO2008101486A3
WO2008101486A3 PCT/DE2008/000301 DE2008000301W WO2008101486A3 WO 2008101486 A3 WO2008101486 A3 WO 2008101486A3 DE 2008000301 W DE2008000301 W DE 2008000301W WO 2008101486 A3 WO2008101486 A3 WO 2008101486A3
Authority
WO
WIPO (PCT)
Prior art keywords
active substance
coated
stent
catheter balloon
expandable system
Prior art date
Application number
PCT/DE2008/000301
Other languages
English (en)
French (fr)
Other versions
WO2008101486A2 (de
Inventor
Michael Orlowski
Original Assignee
Eurocor Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurocor Gmbh filed Critical Eurocor Gmbh
Priority to EP08706903A priority Critical patent/EP2125062A2/de
Priority to BRPI0807618-9A priority patent/BRPI0807618A2/pt
Priority to US12/527,741 priority patent/US20100076542A1/en
Publication of WO2008101486A2 publication Critical patent/WO2008101486A2/de
Publication of WO2008101486A3 publication Critical patent/WO2008101486A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/10—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Die vorliegende Erfindung betrifft ein expandierbares System aus Katheterballon mit einem gekrimpten Stent, wobei dieses System eine schnelle Freisetzungskinetik eines Wirkstoffs mit einer langsamen Freisetzungskinetik eines zweiten Wirkstoff kombiniert, da der Katheterballon mit einem ersten Wirkstoff geeignet für eine schnelle Freisetzung und der Stent mit einem zweiten Wirkstoff geeignet für eine langsamere Freisetzung beschichtet ist. Bei einer bevorzugten Ausführungsform ist der Katheterballon mit einer zytotoxischen Menge eines ersten Wirkstoffs und der Stent mit einer zytostatischen Menge eines zweiten Wirkstoffs beschichtet.
PCT/DE2008/000301 2007-02-21 2008-02-20 Beschichtetes expandierbares system WO2008101486A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08706903A EP2125062A2 (de) 2007-02-21 2008-02-20 Beschichtetes expandierbares system
BRPI0807618-9A BRPI0807618A2 (pt) 2007-02-21 2008-02-20 Sistema expansível revestido
US12/527,741 US20100076542A1 (en) 2007-02-21 2008-02-20 Coated expandable system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102007008479.1 2007-02-21
DE102007008479A DE102007008479A1 (de) 2007-02-21 2007-02-21 Beschichtetes Expandierbares System
US90329807P 2007-02-26 2007-02-26
US60/903,298 2007-02-26

Publications (2)

Publication Number Publication Date
WO2008101486A2 WO2008101486A2 (de) 2008-08-28
WO2008101486A3 true WO2008101486A3 (de) 2009-11-05

Family

ID=39669914

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2008/000301 WO2008101486A2 (de) 2007-02-21 2008-02-20 Beschichtetes expandierbares system

Country Status (6)

Country Link
US (1) US20100076542A1 (de)
EP (1) EP2125062A2 (de)
BR (1) BRPI0807618A2 (de)
DE (1) DE102007008479A1 (de)
RU (1) RU2009135014A (de)
WO (1) WO2008101486A2 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8597720B2 (en) 2007-01-21 2013-12-03 Hemoteq Ag Medical product for treating stenosis of body passages and for preventing threatening restenosis
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory

Families Citing this family (21)

* Cited by examiner, † Cited by third party
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US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
EP3485920B1 (de) 2006-02-09 2020-05-20 B. Braun Melsungen AG Faltenballonbeschichtungsverfahren
WO2008097511A2 (en) * 2007-02-07 2008-08-14 Cook Incorporated Medical device coatings for releasing a therapeutic agent at multiple rates
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US8858995B2 (en) 2008-03-10 2014-10-14 University Of Louisville Research Foundation, Inc. Methods and compositions for controlled delivery of phytochemical agents
US9114125B2 (en) 2008-04-11 2015-08-25 Celonova Biosciences, Inc. Drug eluting expandable devices
DE102008040143A1 (de) * 2008-07-03 2010-01-07 Biotronik Vi Patent Ag Degradierbarer Magnesium-Stent oder Medizinprodukt mit Beschichtung umfassend Dipyridamol
DE102008049469B3 (de) * 2008-09-29 2010-05-12 Siemens Aktiengesellschaft Verfahren zur Überwachung eines Stents
DE102008043277A1 (de) * 2008-10-29 2010-05-06 Biotronik Vi Patent Ag Implantat aus einer biokorrodierbaren Eisen- oder Magnesiumlegierung
DE102009005792B4 (de) * 2009-01-22 2019-06-19 Feg Textiltechnik Forschungs- Und Entwicklungsgesellschaft Mbh Medizinisches Implantat mit Oberflächenbeschichtung
ES2550634T3 (es) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 薬剤送達バルーンの製造方法
DE102010022588A1 (de) * 2010-05-27 2011-12-01 Hemoteq Ag Ballonkatheter mit einer partikelfrei Wirkstoff-abgebenden Beschichtung
JP2013529507A (ja) 2010-06-21 2013-07-22 ゾリオン メディカル インコーポレイテッド 生体吸収性インプラント
WO2012039884A1 (en) 2010-09-23 2012-03-29 Boston Scientific Scimed, Inc. Drug coated balloon with transferable coating
WO2012075311A2 (en) 2010-12-01 2012-06-07 Zorion Medical, Inc. Magnesium-based absorbable implants
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
WO2013148682A1 (en) * 2012-03-26 2013-10-03 University Of Louisville Research Foundation, Inc. Methods and compositions for controlled delivery of phytochemical agents
TWI478943B (zh) * 2012-12-27 2015-04-01 Ind Tech Res Inst 高分子組成物用於製備具有抑制基質金屬蛋白酶之活性的功效的醫療器材或抑制劑的用途
CN110551120B (zh) * 2018-06-04 2020-10-20 首都医科大学 6-氨基酰氨基正己酰咔啉羧酸苄酯,其制备,活性和应用

Citations (3)

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US20030004563A1 (en) * 2001-06-29 2003-01-02 Jackson Gregg A. Polymeric stent suitable for imaging by MRI and fluoroscopy
US20040073284A1 (en) * 2002-07-12 2004-04-15 Cook Incorporated Coated medical device
WO2005089855A1 (en) * 2004-03-19 2005-09-29 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis

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DE19539449A1 (de) 1995-10-24 1997-04-30 Biotronik Mess & Therapieg Verfahren zur Herstellung intraluminaler Stents aus bioresorbierbarem Polymermaterial
DK0981381T3 (da) 1997-05-12 2007-06-04 Metabolix Inc Polyhydroxyalkanoater ti anvendelser in vivo
US6245103B1 (en) 1997-08-01 2001-06-12 Schneider (Usa) Inc Bioabsorbable self-expanding stent
DE59913189D1 (de) * 1998-06-25 2006-05-04 Biotronik Ag Implantierbare, bioresorbierbare Gefässwandstütze, insbesondere Koronarstent
DE19856983A1 (de) 1998-06-25 1999-12-30 Biotronik Mess & Therapieg Implantierbare, bioresorbierbare Gefäßwandstütze, insbesondere Koronarstent
US6419692B1 (en) * 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
EP2305324B1 (de) 1999-03-25 2014-09-17 Metabolix, Inc. Medizinische Geräte und Anwendungen aus Polyhydroxyalkanoat-Polymeren
US6368346B1 (en) 1999-06-03 2002-04-09 American Medical Systems, Inc. Bioresorbable stent
DK1359966T3 (da) * 2001-02-16 2009-10-05 Cordis Corp Fremgangsmåde til fremstilling af et ballonkarteterindföringssystem med furer
DE10244847A1 (de) * 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
DE10253634A1 (de) * 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Endoprothese
US20040111144A1 (en) 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
EP1663343B8 (de) * 2003-09-15 2019-12-04 Atrium Medical Corporation Applikation einer therapeutischen substanz an eine gewebestelle unter verwendung eines expandierbaren medizinprodukts
DE102005039126A1 (de) * 2005-08-18 2007-02-22 Lothar Sellin Parylene-beschichtete expandierbare Vorrichtung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030004563A1 (en) * 2001-06-29 2003-01-02 Jackson Gregg A. Polymeric stent suitable for imaging by MRI and fluoroscopy
US20040073284A1 (en) * 2002-07-12 2004-04-15 Cook Incorporated Coated medical device
WO2005089855A1 (en) * 2004-03-19 2005-09-29 Abbott Laboratories Multiple drug delivery from a balloon and a prosthesis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8597720B2 (en) 2007-01-21 2013-12-03 Hemoteq Ag Medical product for treating stenosis of body passages and for preventing threatening restenosis
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory

Also Published As

Publication number Publication date
US20100076542A1 (en) 2010-03-25
BRPI0807618A2 (pt) 2014-07-22
EP2125062A2 (de) 2009-12-02
WO2008101486A2 (de) 2008-08-28
RU2009135014A (ru) 2011-03-27
DE102007008479A1 (de) 2008-09-04

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