WO2007138103A1 - Use of allopurinol for the treatment of palmar plantar erythrodysesthesia - Google Patents

Use of allopurinol for the treatment of palmar plantar erythrodysesthesia Download PDF

Info

Publication number
WO2007138103A1
WO2007138103A1 PCT/EP2007/055367 EP2007055367W WO2007138103A1 WO 2007138103 A1 WO2007138103 A1 WO 2007138103A1 EP 2007055367 W EP2007055367 W EP 2007055367W WO 2007138103 A1 WO2007138103 A1 WO 2007138103A1
Authority
WO
WIPO (PCT)
Prior art keywords
allopurinol
treatment
chemotherapy
ppe
cancer
Prior art date
Application number
PCT/EP2007/055367
Other languages
English (en)
French (fr)
Inventor
Yolanda Rodemer
Original Assignee
Nobera Pharma, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP06011432A external-priority patent/EP1862166A1/en
Priority to PL07729768T priority Critical patent/PL2035006T3/pl
Priority to EP07729768A priority patent/EP2035006B1/en
Priority to BRPI0711847-3A priority patent/BRPI0711847A2/pt
Priority to MX2008015266A priority patent/MX2008015266A/es
Priority to CA2654270A priority patent/CA2654270C/en
Priority to DK07729768.7T priority patent/DK2035006T3/da
Priority to JP2009512609A priority patent/JP5028480B2/ja
Priority to AU2007267069A priority patent/AU2007267069B2/en
Priority to RSP-2010/0163A priority patent/RS51252B/sr
Application filed by Nobera Pharma, S.L. filed Critical Nobera Pharma, S.L.
Priority to NZ573248A priority patent/NZ573248A/en
Priority to US12/227,807 priority patent/US7973046B2/en
Priority to CN2007800201437A priority patent/CN101460172B/zh
Priority to AT07729768T priority patent/ATE457729T1/de
Priority to DE602007004849T priority patent/DE602007004849D1/de
Publication of WO2007138103A1 publication Critical patent/WO2007138103A1/en
Priority to IL195472A priority patent/IL195472A/en
Priority to KR1020087032168A priority patent/KR101471022B1/ko
Priority to HR20100210T priority patent/HRP20100210T1/hr
Priority to US13/114,768 priority patent/US8557829B2/en
Priority to US14/021,723 priority patent/US20140011820A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
PCT/EP2007/055367 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia WO2007138103A1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DE602007004849T DE602007004849D1 (de) 2006-06-01 2007-05-31 Verwendung von allopurinol zur behandlung von palmarer/plantarer erythrodysästhesie
US12/227,807 US7973046B2 (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
NZ573248A NZ573248A (en) 2006-06-01 2007-05-31 Use of allopurinol (1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) for the treatment of palmar plantar erythrodysesthesia
CN2007800201437A CN101460172B (zh) 2006-06-01 2007-05-31 别嘌醇在制备治疗手足综合征的药物中的用途
EP07729768A EP2035006B1 (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
DK07729768.7T DK2035006T3 (da) 2006-06-01 2007-05-31 Anvendelse af allopurinol til behandling af palmar-plantar erythrodysestesi
JP2009512609A JP5028480B2 (ja) 2006-06-01 2007-05-31 手足症候群の治療のためのアロプリノールの使用
AU2007267069A AU2007267069B2 (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
RSP-2010/0163A RS51252B (sr) 2006-06-01 2007-05-31 Upotreba alopurinola za lečenje palmarno-plantarne eritrodizestezije
PL07729768T PL2035006T3 (pl) 2006-06-01 2007-05-31 Zastosowanie allopurynolu do leczenia erytrodyzestezji dłoniowo-podeszwowej
BRPI0711847-3A BRPI0711847A2 (pt) 2006-06-01 2007-05-31 usos de alopurinol para o tratamento ou prevenção de eritrodisestesia palmo plantar, composição farmacêutica para a administração tópica na pele e método para o tratamento ou prevenção de eritrodisestesia palmo plantar
CA2654270A CA2654270C (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
MX2008015266A MX2008015266A (es) 2006-06-01 2007-05-31 Uso del alopurinol para el tratamiento de la eritrodisestesia palmo-plantar.
AT07729768T ATE457729T1 (de) 2006-06-01 2007-05-31 Verwendung von allopurinol zur behandlung von palmarer/plantarer erythrodysästhesie
IL195472A IL195472A (en) 2006-06-01 2008-11-24 Use of allopurinol for the preparation of a medicament for the treatment of palmar plantar erythrodysesthesia
KR1020087032168A KR101471022B1 (ko) 2006-06-01 2008-12-31 손발바닥 홍반성감각장애의 치료를 위한 알로퓨리놀의 용도
HR20100210T HRP20100210T1 (hr) 2006-06-01 2010-04-14 Upotreba alopurinola u liječenju eritrodisestezije dlana i stopala
US13/114,768 US8557829B2 (en) 2006-06-01 2011-05-24 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
US14/021,723 US20140011820A1 (en) 2006-06-01 2013-09-09 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP06011432A EP1862166A1 (en) 2006-06-01 2006-06-01 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
EP06011432.9 2006-06-01
EP07107744.0 2007-05-08
EP07107744 2007-05-08

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/227,807 A-371-Of-International US7973046B2 (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
US13/114,768 Division US8557829B2 (en) 2006-06-01 2011-05-24 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia

Publications (1)

Publication Number Publication Date
WO2007138103A1 true WO2007138103A1 (en) 2007-12-06

Family

ID=38512579

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/055367 WO2007138103A1 (en) 2006-06-01 2007-05-31 Use of allopurinol for the treatment of palmar plantar erythrodysesthesia

Country Status (21)

Country Link
US (3) US7973046B2 (pt)
EP (1) EP2035006B1 (pt)
JP (3) JP5028480B2 (pt)
KR (1) KR101471022B1 (pt)
AT (1) ATE457729T1 (pt)
AU (1) AU2007267069B2 (pt)
CA (1) CA2654270C (pt)
CY (1) CY1110336T1 (pt)
DE (1) DE602007004849D1 (pt)
DK (1) DK2035006T3 (pt)
ES (1) ES2341379T3 (pt)
HR (1) HRP20100210T1 (pt)
IL (1) IL195472A (pt)
MX (1) MX2008015266A (pt)
NZ (1) NZ573248A (pt)
PL (1) PL2035006T3 (pt)
PT (1) PT2035006E (pt)
RS (1) RS51252B (pt)
RU (1) RU2438673C2 (pt)
SI (1) SI2035006T1 (pt)
WO (1) WO2007138103A1 (pt)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2246057A1 (en) 2009-04-29 2010-11-03 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
EP2368549A1 (en) 2010-03-25 2011-09-28 BioAlliance Pharma Treating hand-foot syndrome and related pathologies using clonidine or its derivatives
EP2712613A1 (en) * 2012-09-28 2014-04-02 Pharmadab d.o.o. Vitamin K1 and uses thereof
US9220713B2 (en) 2009-10-16 2015-12-29 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome
RU2722396C2 (ru) * 2018-07-11 2020-05-29 Федеральное государственное бюджетное учреждение дополнительного профессионального образования "Центральная государственная медицинская академия" Управления делами Президента Российской Федерации (ФГБУ ДПО "ЦГМА") Способ лечения пальмарно-плантарной эритродизестезии

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4983989B2 (ja) * 2010-03-31 2012-07-25 小野薬品工業株式会社 手足症候群の予防および治療剤
US8729056B2 (en) 2010-03-31 2014-05-20 Ono Pharmaceutical Co., Ltd. Preventive and/or therapeutic agent of hand-foot syndrome
JP4761000B1 (ja) * 2010-11-08 2011-08-31 小野薬品工業株式会社 手足症候群の予防および／または治療剤
US9259343B2 (en) 2012-07-06 2016-02-16 Newman Technologies LLC Device for mitigating plantar fasciitis
JP2019512536A (ja) * 2016-03-28 2019-05-16 ヴィダック ファーマ リミテッド 局所投与のための安定な医薬組成物およびその使用
WO2019114705A1 (zh) 2017-12-13 2019-06-20 上海小午医药科技有限公司 一种用于预防或治疗与egfr被抑制相关疾病的方法
KR20200144116A (ko) 2018-04-16 2020-12-28 온퀄리티 파마슈티컬스 차이나 리미티드 암 치료의 부작용을 예방하거나 치료하기 위한 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003018102A2 (en) * 2001-08-29 2003-03-06 Vectura Limited Topical administration device
DE10200578A1 (de) * 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
WO2006030439A2 (en) * 2004-09-17 2006-03-23 Biomas Ltd. Compositions and methods for inducing hair growth

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3011A (en) * 1843-03-21 Improvement in water-wheels
ES2037672T3 (es) 1987-02-13 1993-07-01 Pharm-Allergan Gmbh Utilizacion de pteridinas y/o purinas o de un inhibidor de xantinoxidasa para la fabricacion de un medicamento para el tratamiento de enfermedades degenerativas de la retina condicionadas geneticamente.
JPH03106817A (ja) 1989-09-20 1991-05-07 Nippon Kayaku Co Ltd アロプリノール製剤
JPH066700A (ja) 1992-06-22 1994-01-14 Fujitsu General Ltd ハイビジョン受像機
GB9218711D0 (en) 1992-09-04 1992-10-21 Salim Aws S M Skin cancer treatment
WO1994005293A1 (en) 1992-09-04 1994-03-17 Aws Shakir Mustafa Salim Skin treatment compositions containing dimethylsulphone and allopurinol or oxypurinol
JP3106817B2 (ja) 1993-11-02 2000-11-06 富士電機株式会社 漏電遮断器
US6284234B1 (en) * 1998-08-04 2001-09-04 Johnson & Johnson Consumer Companies, Inc. Topical delivery systems for active agents
US6060083A (en) 1999-04-01 2000-05-09 Topical Technologies, Inc. Topical DMSO treatment for palmar-plantar erythrodysethesia
EP1292265B1 (de) * 2000-06-20 2007-03-21 Henkel Kommanditgesellschaft auf Aktien Verwendung von Vitamin B6-Derivaten zur Haarstrukturverbesserung
DE60117043T2 (de) 2000-11-22 2006-07-13 Rxkinetix, Inc., Louisville Behandlung von mukositis
US7544348B2 (en) 2001-02-15 2009-06-09 Access Pharmaceuticals, Inc. Liquid formulations for the prevention and treatment of mucosal diseases and disorders
US20030157191A1 (en) 2001-11-29 2003-08-21 Sound Pharmaceuticals Incorporated Methods and compositions for ameliorating the undesirable effects of chemotherapy
US6979688B2 (en) * 2002-02-12 2005-12-27 Ford John P Treatment method against side-effects of chemotherapy
US20040214215A1 (en) * 2003-03-07 2004-10-28 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
CA2528359A1 (en) 2003-06-11 2004-12-23 Novacea, Inc. Treatment of cancer with active vitamin d compounds in combination with radiotherapeutic agents and treatments
AU2004247108A1 (en) 2003-06-11 2004-12-23 Novacea, Inc Treatment of immune-mediated disorders with active vitamin D compounds alone or in combination with other therapeutic agents
US20050148910A1 (en) 2003-12-24 2005-07-07 Gregory Skover Apparatus having a skin-contactable element containing an agent
AU2005218539A1 (en) * 2004-03-01 2005-09-15 Lumen Therapeutics, Llc Compositions and methods for treating diseases
JP4405326B2 (ja) 2004-06-28 2010-01-27 株式会社東芝 ランドリー機器

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003018102A2 (en) * 2001-08-29 2003-03-06 Vectura Limited Topical administration device
DE10200578A1 (de) * 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
WO2006030439A2 (en) * 2004-09-17 2006-03-23 Biomas Ltd. Compositions and methods for inducing hair growth

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DAGHER G ET AL: "ALLOPURINOL MOUTHWASH AND VAGINAL CREAM FOR 5-FU-INDUCED MUCOSITIS", CANADIAN JOURNAL OF HOSPITAL PHARMACY, vol. 40, no. 5, 1987, pages 189, XP009075859, ISSN: 0008-4123 *
EL-ON J ET AL: "DEVELOPMENT OF TOPICAL TREATMENT FOR CUTANEOUS LEISHMANIASIS CAUSED BY LEISHMANIA-MAJOR IN EXPERIMENTAL ANIMALS", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 26, no. 5, 1984, pages 745 - 751, XP009075856, ISSN: 0066-4804 *
GILBAR P: "Palmar-plantar erythrodysesthesia", JOURNAL OF ONCOLOGY PHARMACY PRACTICE 2003 UNITED STATES, vol. 9, no. 4, 2003, pages 137 - 150, XP002410373, ISSN: 1078-1552 *
TSAVARIS N ET AL: "CONCOMITANT ADMINISTRATION OF 4 HYDROXYPYRAZOLOPYRIMIDINE ALLOPURINOL AND HIGH-DOSE CONTINUOUS INFUSION 5 FLUOROURACIL", ONCOLOGY (BASEL), vol. 47, no. 1, 1990, pages 70 - 74, XP009075852, ISSN: 0030-2414 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2543325C2 (ru) * 2009-04-29 2015-02-27 Нобера Фарма, С.Л. Применение аллопуринола для лечения ладонно-подошвенного синдрома
US20100280051A1 (en) * 2009-04-29 2010-11-04 Yolanda Rodemer Use of allopurinol for the treatment of hand foot skin reaction
WO2010125143A1 (en) * 2009-04-29 2010-11-04 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
CN102421436A (zh) * 2009-04-29 2012-04-18 诺贝拉药物公司 别嘌呤醇在用于治疗手足皮肤反应中的用途
JP2012525358A (ja) * 2009-04-29 2012-10-22 ノベラ ファルマ ソシエダッド リミターダ 手足皮膚反応治療のためのアロプリノールの使用
US8623878B2 (en) 2009-04-29 2014-01-07 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
CN102421436B (zh) * 2009-04-29 2014-05-07 诺贝拉药物公司 别嘌呤醇在制备用于治疗手足皮肤反应的药物中的用途
EP2246057A1 (en) 2009-04-29 2010-11-03 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
US9220713B2 (en) 2009-10-16 2015-12-29 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome
US9629845B2 (en) 2009-10-16 2017-04-25 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome
EP2368549A1 (en) 2010-03-25 2011-09-28 BioAlliance Pharma Treating hand-foot syndrome and related pathologies using clonidine or its derivatives
EP2712613A1 (en) * 2012-09-28 2014-04-02 Pharmadab d.o.o. Vitamin K1 and uses thereof
RU2722396C2 (ru) * 2018-07-11 2020-05-29 Федеральное государственное бюджетное учреждение дополнительного профессионального образования "Центральная государственная медицинская академия" Управления делами Президента Российской Федерации (ФГБУ ДПО "ЦГМА") Способ лечения пальмарно-плантарной эритродизестезии

Also Published As

Publication number Publication date
JP5389980B2 (ja) 2014-01-15
US7973046B2 (en) 2011-07-05
US20140011820A1 (en) 2014-01-09
JP2009542581A (ja) 2009-12-03
RS51252B (sr) 2010-12-31
PT2035006E (pt) 2010-04-22
DK2035006T3 (da) 2010-04-19
DE602007004849D1 (de) 2010-04-01
US8557829B2 (en) 2013-10-15
EP2035006B1 (en) 2010-02-17
IL195472A (en) 2012-04-30
PL2035006T3 (pl) 2010-07-30
SI2035006T1 (sl) 2010-04-30
CA2654270C (en) 2014-05-13
HRP20100210T1 (hr) 2010-05-31
US20090306097A1 (en) 2009-12-10
RU2438673C2 (ru) 2012-01-10
RU2008152341A (ru) 2010-07-20
JP2012180370A (ja) 2012-09-20
AU2007267069B2 (en) 2011-08-11
CY1110336T1 (el) 2015-01-14
IL195472A0 (en) 2011-08-01
JP5028480B2 (ja) 2012-09-19
ATE457729T1 (de) 2010-03-15
CA2654270A1 (en) 2007-12-06
KR20090031697A (ko) 2009-03-27
NZ573248A (en) 2011-01-28
ES2341379T3 (es) 2010-06-18
US20110224237A1 (en) 2011-09-15
EP2035006A1 (en) 2009-03-18
AU2007267069A1 (en) 2007-12-06
MX2008015266A (es) 2009-02-10
KR101471022B1 (ko) 2014-12-09
JP2014028851A (ja) 2014-02-13

Similar Documents

Publication Publication Date Title
AU2007267069B2 (en) Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
AU2016228193A1 (en) Use of allopurinol for the treatment of hand foot skin reaction
US20230226083A1 (en) Compositions and methods for deep dermal drug delivery
EP1862166A1 (en) Use of allopurinol for the treatment of palmar plantar erythrodysesthesia

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780020143.7

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07729768

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2007267069

Country of ref document: AU

Ref document number: 2009512609

Country of ref document: JP

Ref document number: 573248

Country of ref document: NZ

ENP Entry into the national phase

Ref document number: 2654270

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: MX/A/2008/015266

Country of ref document: MX

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007729768

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 1020087032168

Country of ref document: KR

ENP Entry into the national phase

Ref document number: 2007267069

Country of ref document: AU

Date of ref document: 20070531

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2008152341

Country of ref document: RU

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 12227807

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: P-2010/0163

Country of ref document: RS

ENP Entry into the national phase

Ref document number: PI0711847

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20081128