WO2007025098A3 - Composes de triazole et preparation et utilisation de ces composes - Google Patents

Composes de triazole et preparation et utilisation de ces composes Download PDF

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Publication number
WO2007025098A3
WO2007025098A3 PCT/US2006/033170 US2006033170W WO2007025098A3 WO 2007025098 A3 WO2007025098 A3 WO 2007025098A3 US 2006033170 W US2006033170 W US 2006033170W WO 2007025098 A3 WO2007025098 A3 WO 2007025098A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
making
methods
same
triazole compounds
Prior art date
Application number
PCT/US2006/033170
Other languages
English (en)
Other versions
WO2007025098A2 (fr
Inventor
Ashoke Bhattacharjee
Yi Chen
Yanming Du
Jay J Farmer
Joel A Goldberg
Zoltan F Kanyo
Rongliang Lou
Edward C Sherer
Yuanqing Tang
Yusheng Wu
Original Assignee
Rib X Pharmaceuticals Inc
Ashoke Bhattacharjee
Yi Chen
Yanming Du
Jay J Farmer
Joel A Goldberg
Zoltan F Kanyo
Rongliang Lou
Edward C Sherer
Yuanqing Tang
Yusheng Wu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rib X Pharmaceuticals Inc, Ashoke Bhattacharjee, Yi Chen, Yanming Du, Jay J Farmer, Joel A Goldberg, Zoltan F Kanyo, Rongliang Lou, Edward C Sherer, Yuanqing Tang, Yusheng Wu filed Critical Rib X Pharmaceuticals Inc
Priority to EP06824847A priority Critical patent/EP1928893A2/fr
Priority to JP2008528168A priority patent/JP2009506066A/ja
Publication of WO2007025098A2 publication Critical patent/WO2007025098A2/fr
Publication of WO2007025098A3 publication Critical patent/WO2007025098A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Abstract

L'invention concerne des composés macrocycliques de triazoles utiles en tant qu'agents thérapeutiques, et plus particulièrement en tant qu'agents anti-infectieux, antiprolifératifs, anti-inflammatoires et prokinétiques.
PCT/US2006/033170 2005-08-24 2006-08-24 Composes de triazole et preparation et utilisation de ces composes WO2007025098A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06824847A EP1928893A2 (fr) 2005-08-24 2006-08-24 Composes de triazole et preparation et utilisation de ces composes
JP2008528168A JP2009506066A (ja) 2005-08-24 2006-08-24 トリアゾール化合物ならびにこれを作製する方法および使用する方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US71144305P 2005-08-24 2005-08-24
US60/711,443 2005-08-24
US76290706P 2006-01-26 2006-01-26
US60/762,907 2006-01-26

Publications (2)

Publication Number Publication Date
WO2007025098A2 WO2007025098A2 (fr) 2007-03-01
WO2007025098A3 true WO2007025098A3 (fr) 2007-04-26

Family

ID=37467427

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2006/033645 WO2007025284A1 (fr) 2005-08-24 2006-08-24 Composes de triazole et procedes de fabrication et d'utilisation associes
PCT/US2006/033170 WO2007025098A2 (fr) 2005-08-24 2006-08-24 Composes de triazole et preparation et utilisation de ces composes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2006/033645 WO2007025284A1 (fr) 2005-08-24 2006-08-24 Composes de triazole et procedes de fabrication et d'utilisation associes

Country Status (7)

Country Link
US (5) US8278281B2 (fr)
EP (3) EP3290427A1 (fr)
JP (6) JP2009506066A (fr)
DK (1) DK1934238T3 (fr)
ES (1) ES2638427T3 (fr)
HR (1) HRP20171285T1 (fr)
WO (2) WO2007025284A1 (fr)

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CN102816194A (zh) 2004-02-27 2012-12-12 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
WO2007025089A2 (fr) 2005-08-24 2007-03-01 Rib-X Pharmaceutical, Inc. Triazoles et procedes de production et d'utilisation de ces composes
WO2007025284A1 (fr) * 2005-08-24 2007-03-01 Rib-X Pharmaceuticals, Inc. Composes de triazole et procedes de fabrication et d'utilisation associes
WO2008143730A2 (fr) * 2007-02-28 2008-11-27 Rib-X Pharmaceuticals, Inc. Composés macrolides et procédés pour leur fabrication et leur utilisation
EP2192111A3 (fr) * 2007-07-06 2010-10-06 Paratek Pharmaceuticals, Inc. Procédés servant à synthétiser des composés de tétracycline substituée
JP2011026260A (ja) * 2009-07-28 2011-02-10 Central Glass Co Ltd ３位に脱離基を有する２−フルオロプロピルアミン保護体または該アミンｎ−アルキル保護体
CN101619085B (zh) * 2009-08-11 2015-04-22 沈阳药科大学 红霉素衍生物及其作为肿瘤细胞增殖抑制剂的用途
AR092278A1 (es) * 2012-08-31 2015-04-08 Novartis Ag Proceso de obtencion de derivados n-acilicos de bifenil-alanina e intermediarios relacionados
EP3217974A4 (fr) 2014-11-14 2018-07-25 Melinta Subsidiary Corp. Méthode de traitement, de prévention ou de réduction du risque d'une infection cutanée
WO2018191682A1 (fr) * 2017-04-15 2018-10-18 Melinta Therapeutics, Inc. Composés de triazole et procédés de fabrication et d'utilisation de ceux-ci
CN110108826A (zh) * 2019-05-24 2019-08-09 内蒙古蒙牛乳业（集团）股份有限公司 乳或乳制品中氟苯尼考胺的检测方法
BR112022021346A2 (pt) * 2020-04-24 2022-12-06 Kansas Soybean Commission Síntese em uma etapa de polióis de soja
CN115745823B (zh) * 2022-11-03 2024-02-23 武夷学院 一种化合物的制备方法及其应用

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WO2005019211A2 (fr) * 2003-06-03 2005-03-03 Rib-X Pharmaceuticals, Inc. Composes heterocycliques biaryle et procedes de production et d'utilisation associes
WO2005085266A2 (fr) * 2004-02-27 2005-09-15 Rib-X Pharmaceuticals, Inc. Composes macrocycliques et leurs procedes de fabrication et d'utilisation

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Publication number Priority date Publication date Assignee Title
WO2004029066A2 (fr) * 2002-09-26 2004-04-08 Rib-X Pharmaceuticals, Inc. Composes heterocycliques bifonctionnels et procedes de fabrication et d'utilisation de ces composes
WO2005019211A2 (fr) * 2003-06-03 2005-03-03 Rib-X Pharmaceuticals, Inc. Composes heterocycliques biaryle et procedes de production et d'utilisation associes
WO2005085266A2 (fr) * 2004-02-27 2005-09-15 Rib-X Pharmaceuticals, Inc. Composes macrocycliques et leurs procedes de fabrication et d'utilisation

Also Published As

Publication number Publication date
US20140088031A1 (en) 2014-03-27
JP2019023194A (ja) 2019-02-14
EP1934238A1 (fr) 2008-06-25
JP2009506075A (ja) 2009-02-12
WO2007025284A8 (fr) 2007-04-26
US9006189B2 (en) 2015-04-14
ES2638427T3 (es) 2017-10-20
JP2013256517A (ja) 2013-12-26
DK1934238T3 (en) 2017-09-18
WO2007025098A2 (fr) 2007-03-01
EP1928893A2 (fr) 2008-06-11
US20100016956A1 (en) 2010-01-21
JP2016094421A (ja) 2016-05-26
JP5395432B2 (ja) 2014-01-22
WO2007025284A1 (fr) 2007-03-01
US20160031926A1 (en) 2016-02-04
HRP20171285T1 (hr) 2017-10-20
EP3290427A1 (fr) 2018-03-07
JP2009506066A (ja) 2009-02-12
JP5981401B2 (ja) 2016-08-31
US20130065845A1 (en) 2013-03-14
EP1934238B1 (fr) 2017-06-28
JP2018008970A (ja) 2018-01-18
US20180094016A1 (en) 2018-04-05
US8278281B2 (en) 2012-10-02

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