WO2005084569A1 - Gas plasma tissue resurfacing instrument - Google Patents

Gas plasma tissue resurfacing instrument Download PDF

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Publication number
WO2005084569A1
WO2005084569A1 PCT/GB2005/000804 GB2005000804W WO2005084569A1 WO 2005084569 A1 WO2005084569 A1 WO 2005084569A1 GB 2005000804 W GB2005000804 W GB 2005000804W WO 2005084569 A1 WO2005084569 A1 WO 2005084569A1
Authority
WO
WIPO (PCT)
Prior art keywords
disposable assembly
gas
instrument
plasma
power
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2005/000804
Other languages
English (en)
French (fr)
Inventor
Colin Charles Owen Goble
Keith Penny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhytec Ltd
Original Assignee
Rhytec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhytec Ltd filed Critical Rhytec Ltd
Priority to JP2007501347A priority Critical patent/JP2007526063A/ja
Priority to EP05717882A priority patent/EP1720475B8/en
Priority to DE602005025851T priority patent/DE602005025851D1/de
Priority to AU2005220056A priority patent/AU2005220056A1/en
Publication of WO2005084569A1 publication Critical patent/WO2005084569A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00—Generating plasma; Handling plasma
    • H05H1/24—Generating plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/042—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating using additional gas becoming plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00—Generating plasma; Handling plasma
    • H05H1/24—Generating plasma
    • H05H1/46—Generating plasma using applied electromagnetic fields, e.g. high frequency or microwave energy
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00—Generating plasma; Handling plasma
    • H05H1/24—Generating plasma
    • H05H1/46—Generating plasma using applied electromagnetic fields, e.g. high frequency or microwave energy
    • H05H1/4645—Radiofrequency discharges
    • H05H1/466—Radiofrequency discharges using capacitive coupling means, e.g. electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091—Handpieces of the surgical instrument or device
    • H—ELECTRICITY
    • H03—ELECTRONIC CIRCUITRY
    • H03K—PULSE TECHNIQUE
    • H03K3/00—Circuits for generating electric pulses; Monostable, bistable or multistable circuits
    • H03K3/02—Generators characterised by the type of circuit or by the means used for producing pulses
    • H03K3/37—Generators characterised by the type of circuit or by the means used for producing pulses by the use, as active elements, of gas-filled tubes, e.g. astable trigger circuits
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H2242/00—Auxiliary systems
    • H05H2242/20—Power circuits
    • H05H2242/26—Matching networks

Definitions

  • Operation of the system comprises the steps of: receiving input signals from a user, and operating the controller to determine from the user input signals a manner in which the power output device is to be controlled; operating the power output device to supply a voltage to the at least one electrode, thereby to create an electric field in the region of the electrode; passing gas through the electric field, and creating by virtue of the intensity of the electric field a plasma from the gas; and controlling, in accordance with the user input signals to the controller, the power output device to control the power delivered into the plasma.
  • the controller may operate to control the power output device to deliver a predetermined level of energy into the plasma, and the controller may further control the rate of flow of gas through the electric field.
  • Also described in this specification is a method of operating a tissue treatment instrument having first and second pairs of electrodes, the electrodes of each pair being connected to different output terminals of a power output device which generates an oscillating electrical output signal, the method comprising the steps of: operating the power output device to apply an oscillating electrical signal to the first and second pairs of electrodes; causing resonance of resonant assembly of which the first pair of electrodes form at least a part; creating, by virtue of the resonance, a potential difference and thus an electric field between an electrode of the first pair of electrodes and an electrode of the second pair of electrodes; passing a gas through the electric field and, by virtue of interaction between the electric field and the gas, forming a plasma.
  • Figure 10 is a graph illustrating the switch-on characteristics of the magnetron in the generator of Figure 8.
  • Figure 12 is a block diagram of intermediate and inner power control loops of the generator of Figure 8.
  • Figure 18 is a schematic illustration of a further embodiment of instrument.
  • the gas should include a diatomic gas (or gas having more than two atoms), for example, nitrogen, carbon dioxide or air.
  • the generator operates to establish an electric field in the region of the tip 22 of the electrode. Gas from the supply 18 is passed through the electric field. If the field is sufficiently strong, it will have the effect of accelerating free electrons sufficiently to cause collisions with the gas molecules, the result of which is either the dissociation of one or more electrons from the gas molecules to create gaseous ions, or the excitation of electrons in the gas molecules to higher energy states, or dissociation of molecules into constituent atoms, or the excitation of vibrational states in the gaseous molecules.
  • the result in macroscopic terms is the creation of a plasma 24 which is hot.
  • the resultant plasma 72 passes out of an aperture 80 formed in a ceramic disc 82 in the distal end of the instrument largely under the influence of the pressure from the nitrogen supply; the insulating nature of the disc 82 serving to reduce or avoid preferential arcing between the electrodes 60 and 70.
  • an instrument for use with a generator having a magnetron power output device comprises, as with the instrument of Figures 2, 3 and 6, an outer shaft 30, connector 26, coaxial feed cable 40.
  • a transitional impedance matching structure includes a low impedance section 92 and a high impedance section 94, and provides a match between the power output device of the generator and the load provided by the plasma, which is created in an electric field between a central disc electrode 160 and an outer electrode 70 provided by a section of the conductive sleeve adjacent the disc electrode 160.
  • the needle electrode 54 is made of heat resistant conductor such as tungsten and has a diameter such that, in combination with the outer sleeve 50, it forms a transmission line section of higher characteristic impedance than that of the connector 26, typically in the region of 90 to 120 ⁇ .
  • the length of the needle electrode i.e. the distance from the connector inner conductor extension 42 to its tip 54T (see Figure 20)
  • it can be made to act as an impedance transformation element raising the voltage at the tip 54T to a level significantly higher than that seen on the 50 ⁇ section (inner conductor extension 42).
  • an intense E-field is created between the tip 54T of the inner electrode needle and the adjacent outer conductor distal end portion 70.
  • This in itself, given sufficient input power, can be enough to create a gas plasma extending downstream from the tip 54T and through the nozzle 180N.
  • more reliable striking of the plasma is achieved due to the presence of the focussing element 480.
  • This focussing element 480 is a resonant element dimensioned to have a resonant frequency when in-situ in the quartz tube, in the region of the operating frequency of the instrument and its associated generator.
  • the resonant element 480 has three portions, i.e. first and second folded patch elements 480C, folded into irregular rings dimensioned to engage the inside of the quartz tube 180, and an interconnecting intermediate narrow strip 480L.
  • These components are all formed from a single piece of conductive material, here spring stainless steel, the resilience of which causes the element to bear against tube 180.
  • a gas inlet 513 passes through the end cover 504, and communicates via a lumen 514 within the casing, through the gas inlet hole 509 in the outer electrode, and through further channels 515 in the insulator 512, exiting in the region of the distal end of the inner electrode 506.
  • a resonator in the form of a helically wound tungsten coil 521 is located within the tube 516, the coil 521 being positioned such that, when the disposable assembly 502 is secured in position on the handpiece 501, the proximal end of the coil is adjacent the distal end of the inner electrode 506.
  • the coil is wound such that it is adjacent and in intimate contact with the inner surface of the quartz tube 516.
  • UHF signals are not essential to the operation of the present invention, and the invention may be embodied at any frequency from DC signals upwards.
  • the use of UHF signals has an advantage in that components whose length is one quarter wavelength long may be incorporated within compact surgical instruments to provide voltage transformation or matching.
  • several instruments have been illustrated which have resonant assemblies for the purpose of step-up voltage transformation, but this is not essential, and upward voltage transformation can be performed within an instrument without making use of resonance.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Plasma & Fusion (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electromagnetism (AREA)
  • Surgical Instruments (AREA)
  • Plasma Technology (AREA)
PCT/GB2005/000804 2004-03-05 2005-03-03 Gas plasma tissue resurfacing instrument Ceased WO2005084569A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2007501347A JP2007526063A (ja) 2004-03-05 2005-03-03 ガスプラズマ組織リサーフェイシング器具
EP05717882A EP1720475B8 (en) 2004-03-05 2005-03-03 Gas plasma tissue resurfacing instrument
DE602005025851T DE602005025851D1 (de) 2004-03-05 2005-03-03 Gas-plasma-instrument zur wiederherstellung von gewebeoberflächen
AU2005220056A AU2005220056A1 (en) 2004-03-05 2005-03-03 Gas plasma tissue resurfacing instrument

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/792,765 US7335199B2 (en) 2000-02-22 2004-03-05 Tissue resurfacing
US10/792,765 2004-03-05

Publications (1)

Publication Number Publication Date
WO2005084569A1 true WO2005084569A1 (en) 2005-09-15

Family

ID=34919743

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2005/000804 Ceased WO2005084569A1 (en) 2004-03-05 2005-03-03 Gas plasma tissue resurfacing instrument

Country Status (8)

Country Link
US (2) US7335199B2 (https=)
EP (2) EP1720475B8 (https=)
JP (1) JP2007526063A (https=)
KR (1) KR20060134099A (https=)
AU (1) AU2005220056A1 (https=)
DE (1) DE602005025851D1 (https=)
ES (1) ES2361524T3 (https=)
WO (1) WO2005084569A1 (https=)

Cited By (19)

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EP1658817A1 (en) * 2004-11-23 2006-05-24 Rhytec Limited Usage limiting electronic key system for plasma device for tissue resurfacing
US7300436B2 (en) 2000-02-22 2007-11-27 Rhytec Limited Tissue resurfacing
WO2008125810A1 (en) * 2007-04-12 2008-10-23 Rhytec Limited A tissue treatment system and a method of cosmetic tissue treatment
GB2458329A (en) * 2008-03-15 2009-09-16 Microoncology Ltd Applicator for plasma sterilisation of body cavities
JP2010519693A (ja) * 2007-02-26 2010-06-03 ドクトル・ラウレ・プラスマテヒノロギー・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 体積の大きな構成部品にプラズマ支援によるコーティングおよび表面処理を施す装置および方法
WO2011015538A1 (de) * 2009-08-03 2011-02-10 Leibniz-Institut Für Plasmaforschung Und Technologie E. V. Vorrichtung zur erzeugung eines nichtthermischen atmosphärendruck-plasmas
EP2145514A4 (en) * 2007-04-23 2012-03-14 Cold Plasma Medical Technologies Inc HARMONIOUS CALALTY LASMA DEVICE AND METHOD THEREFOR
WO2014111935A1 (en) 2013-01-16 2014-07-24 Orteron (T.O) Ltd. Physical means and methods for inducing regenerative effects on living tissues and fluids
US8928230B2 (en) 2008-02-27 2015-01-06 Cold Plasma Medical Technologies, Inc. Cold plasma treatment devices and associated methods
US9295280B2 (en) 2012-12-11 2016-03-29 Plasmology4, Inc. Method and apparatus for cold plasma food contact surface sanitation
US9440057B2 (en) 2012-09-14 2016-09-13 Plasmology4, Inc. Therapeutic applications of cold plasma
US9472382B2 (en) 2007-04-23 2016-10-18 Plasmology4, Inc. Cold plasma annular array methods and apparatus
US9521736B2 (en) 2007-04-23 2016-12-13 Plasmology4, Inc. Cold plasma electroporation of medication and associated methods
DE102015119990A1 (de) 2015-10-06 2017-04-06 Orteron (T.O) Ltd. Ein Verfahren zum Steuern von biologischen Prozessen in Mikroorganismen
US9656095B2 (en) 2007-04-23 2017-05-23 Plasmology4, Inc. Harmonic cold plasma devices and associated methods
US10039927B2 (en) 2007-04-23 2018-08-07 Plasmology4, Inc. Cold plasma treatment devices and associated methods
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DE602005025851D1 (de) 2011-02-24
US20040186470A1 (en) 2004-09-23
US20050256519A1 (en) 2005-11-17
KR20060134099A (ko) 2006-12-27
US7335199B2 (en) 2008-02-26
AU2005220056A1 (en) 2005-09-15
EP2301460B1 (en) 2013-08-21
JP2007526063A (ja) 2007-09-13
EP1720475B8 (en) 2011-03-02
EP1720475B1 (en) 2011-01-12
ES2361524T3 (es) 2011-06-17
EP2301460A1 (en) 2011-03-30

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