WO2005072055A9 - Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation - Google Patents

Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation Download PDF

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Publication number
WO2005072055A9
WO2005072055A9 PCT/IB2005/000995 IB2005000995W WO2005072055A9 WO 2005072055 A9 WO2005072055 A9 WO 2005072055A9 IB 2005000995 W IB2005000995 W IB 2005000995W WO 2005072055 A9 WO2005072055 A9 WO 2005072055A9
Authority
WO
WIPO (PCT)
Prior art keywords
methods
natriuretic peptide
brain natriuretic
peptide variants
novel brain
Prior art date
Application number
PCT/IB2005/000995
Other languages
English (en)
Other versions
WO2005072055A2 (fr
Inventor
Gad S. Cojocaru
Alexander Diber
Amit Novik
Sarah Pollock
Zurit Levine
Yossi Cohen
Michal Ayalon-Soffer
Original Assignee
Compugen Usa, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Usa, Inc. filed Critical Compugen Usa, Inc.
Priority to AU2005207886A priority Critical patent/AU2005207886A1/en
Priority to EP05718453A priority patent/EP1730181A2/fr
Priority to CA002554599A priority patent/CA2554599A1/fr
Priority to JP2006550367A priority patent/JP2007525213A/ja
Priority claimed from US11/043,590 external-priority patent/US7332569B2/en
Publication of WO2005072055A2 publication Critical patent/WO2005072055A2/fr
Publication of WO2005072055A9 publication Critical patent/WO2005072055A9/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
PCT/IB2005/000995 2004-01-27 2005-01-27 Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation WO2005072055A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2005207886A AU2005207886A1 (en) 2004-01-27 2005-01-27 Novel brain natriuretic peptide variants and methods of use thereof
EP05718453A EP1730181A2 (fr) 2004-01-27 2005-01-27 Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation
CA002554599A CA2554599A1 (fr) 2004-01-27 2005-01-27 Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation
JP2006550367A JP2007525213A (ja) 2004-01-27 2005-01-27 新規の脳性ナトリウム利尿ペプチドの変異体及びその利用方法

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US53912704P 2004-01-27 2004-01-27
US60/539,127 2004-01-27
US58785104P 2004-07-15 2004-07-15
US60/587,851 2004-07-15
US60724604P 2004-09-07 2004-09-07
US60/607,246 2004-09-07
US60/622,320 2004-10-25
US62232004P 2004-10-27 2004-10-27
US62201604P 2004-10-27 2004-10-27
US60/622,016 2004-10-27
US62819004P 2004-11-17 2004-11-17
US60/628,190 2004-11-17
US11/043,590 2005-01-27
US11/043,590 US7332569B2 (en) 2004-01-27 2005-01-27 Brain natriuretic peptide spliced variant

Publications (2)

Publication Number Publication Date
WO2005072055A2 WO2005072055A2 (fr) 2005-08-11
WO2005072055A9 true WO2005072055A9 (fr) 2011-02-17

Family

ID=34831546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/000995 WO2005072055A2 (fr) 2004-01-27 2005-01-27 Nouveaux variants de peptides cerebraux natriuretiques et leurs procede d'utilisation

Country Status (4)

Country Link
EP (1) EP1730181A2 (fr)
AU (1) AU2005207886A1 (fr)
CA (1) CA2554599A1 (fr)
WO (1) WO2005072055A2 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1638443T3 (da) 2003-06-20 2011-02-07 Mayo Foundation Isoformer af hjerne-natriuretisk peptid
HUE039448T2 (hu) 2004-04-21 2018-12-28 Alexion Pharma Inc Csontba szállító konjugátumok és alkalmazási módszerük a fehérjék csontba juttatására
CA2647143A1 (fr) 2006-03-30 2007-10-11 Palatin Technologies, Inc. Constructions de peptides natriuretiques cycliques
JP5702930B2 (ja) 2006-08-08 2015-04-15 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 利尿ポリペプチドおよびナトリウム利尿ポリペプチド
WO2008031045A2 (fr) 2006-09-08 2008-03-13 Mayo Foundation For Medical Education And Research Polypeptides aquarétiques et natriurétiques dépourvus d'activité vasodilatatoire
US9086408B2 (en) 2007-04-30 2015-07-21 Nexus Dx, Inc. Multianalyte assay
WO2009036448A2 (fr) 2007-09-15 2009-03-19 Mayo Foundation For Medical Education And Research Agonistes des récepteurs peptidiques natriurétiques de type c
TWI686405B (zh) 2008-12-09 2020-03-01 建南德克公司 抗ｐｄ-ｌ１抗體及其於增進ｔ細胞功能之用途
RU2572694C2 (ru) 2009-07-23 2016-01-20 ИГИСУ Ко., Лтд. Композиция кожного препарата для наружного применения
BR112012004058A2 (pt) 2009-08-27 2021-08-17 Kyoko Endo preparação terapêutica para rinite
EP2658979B1 (fr) 2010-12-27 2018-02-14 Alexion Pharmaceuticals, Inc. Compositions contenant des peptides natriurétiques et leurs méthodes d'utilisation
ES2647680T3 (es) 2011-01-21 2017-12-26 Igisu Co., Ltd. Fármaco terapéutico para la alopecia
SG10201601086WA (en) * 2011-08-18 2016-03-30 Otago Innovation Ltd Cardiovascular therapeutics
CN103906761B (zh) 2011-08-30 2016-12-21 梅约医学教育与研究基金会 利钠多肽
US9611305B2 (en) 2012-01-06 2017-04-04 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
WO2016007873A1 (fr) 2014-07-11 2016-01-14 The Regents Of The University Of Michigan Compositions et méthodes de traitement de la craniosynostose
JP6787894B2 (ja) 2014-12-05 2020-11-18 アレクシオン ファーマシューティカルズ， インコーポレイテッド 組換えアルカリホスファターゼを用いた発作の処置
AU2016211447B2 (en) 2015-01-28 2021-09-23 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
KR102644116B1 (ko) 2015-08-17 2024-03-05 알렉시온 파마슈티칼스, 인코포레이티드 알칼린 포스파타제의 제조
EP3355904A4 (fr) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. Identification de régimes posologiques efficaces pour une thérapie de l'hypophosphatasie de remplacement de l'enzyme phosphatase alcaline non spécifique à des tissus (tnsalp)
EP3368062A4 (fr) 2015-10-30 2019-07-03 Alexion Pharmaceuticals, Inc. Méthodes de traitement de la craniosynostose chez un patient
EP3426286A4 (fr) 2016-03-08 2019-12-04 Alexion Pharmaceuticals, Inc. Méthodes de traitement de l'hypophosphatasie chez l'enfant
EP3436020A4 (fr) 2016-04-01 2019-12-25 Alexion Pharmaceuticals, Inc. Méthodes de traitement de l'hypophosphatasie chez les adolescents et les adultes
MX2018011833A (es) 2016-04-01 2019-02-13 Alexion Pharma Inc Tratamiento para la debilidad muscular con fosfatasas alcalinas.
US10988744B2 (en) 2016-06-06 2021-04-27 Alexion Pharmaceuticals, Inc. Method of producing alkaline phosphatase
US11116821B2 (en) 2016-08-18 2021-09-14 Alexion Pharmaceuticals, Inc. Methods for treating tracheobronchomalacia
US9611297B1 (en) 2016-08-26 2017-04-04 Thrasos Therapeutics Inc. Compositions and methods for the treatment of cast nephropathy and related conditions
AU2018243320A1 (en) 2017-03-31 2019-10-10 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia (HPP) in adults and adolescents
WO2019190752A1 (fr) 2018-03-30 2019-10-03 Alexion Pharmaceuticals, Inc. Production de glycoprotéines

Also Published As

Publication number Publication date
EP1730181A2 (fr) 2006-12-13
AU2005207886A1 (en) 2005-08-11
WO2005072055A2 (fr) 2005-08-11
CA2554599A1 (fr) 2005-08-11

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