WO2005044345A1 - Autoinjektionsvorrichtung - Google Patents
Autoinjektionsvorrichtung Download PDFInfo
- Publication number
- WO2005044345A1 WO2005044345A1 PCT/CH2004/000652 CH2004000652W WO2005044345A1 WO 2005044345 A1 WO2005044345 A1 WO 2005044345A1 CH 2004000652 W CH2004000652 W CH 2004000652W WO 2005044345 A1 WO2005044345 A1 WO 2005044345A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- needle
- injection device
- injection
- ampoule
- tool
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3213—Caps placed axially onto the needle, e.g. equipped with finger protection guards
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
- A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3104—Caps for syringes without needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
- A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
- A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
Definitions
- the present invention relates to a device, such as an injection device or a pen, for the preferably metered delivery of, for example, a medical substance, for example insulin or hormones.
- a device such as an injection device or a pen
- a medical substance for example insulin or hormones.
- the invention relates to an auto-injection device, which can be designed, for example, for single use as a disposable injection device.
- FIG. 3 shows a known injection device 10 with a needle 5 arranged in the injection device 10, which is surrounded by a needle protection element 1 and a needle protection cap 6, the needle protection element 1 being supported by a needle protection spring 3 which is supported against the housing 14 of the injection device 10 is pressed into the front dispensing direction of the injection device 10, which is arranged on the left in FIG.
- the injection device 10 shown in FIG. 3 is placed on the injection site with the front of the needle protection element 1 after the removal of the needle protection cap 6, and the needle protection element 1 must be pushed back against the force of the needle protection spring 3 in order to use the needle 5 stabbing.
- Pushing the needle protection element 1 back against the force exerted by the needle protection spring 3 over the distance D has the consequence that a user of the injection device 10 over a longer period of time with a relatively large pressure on the injection site press to perform the injection. If a substance or a medication is stored in the ampoule 11 which is not long-term with metal, for example with the needle 5, it is necessary to place the needle 5 on the ampoule 11 shortly before the injection, which is practically impossible with the injection device 10 shown in FIG.
- the present invention relates to a preparation device or a tool for preparing an injection device, in particular an auto-injection device, which can be designed, for example, as a disposable part for single use, for carrying out an injection, an ampoule with a dispenser being dispensed in the injection device Substance, such as a drug, is provided and the ampoule is closed and, for example, is provided with a protective cap in a known manner.
- Known protective caps of this type consist of a rubber part which closes the ampoule, this rubber part being secured to the ampoule, for example with a plastic cap, which for example can also include a thread for a Luer needle.
- a predetermined breaking point is preferably provided on the plastic cap, which can be broken open, for example, by turning or pulling, so that the rubber part with the broken-off plastic part can be removed in order to open the ampoule.
- a connection element for a needle is provided on the closure, it is possible, for example, to screw on or plug on a Luer needle.
- the preparation device or the tool is already connected to the closure or the protective cap of the ampoule, for example, in the initial state, or can be connected to it, so that it is possible to rotate and / or pull the preparation device to protect the ampoule or the tool, for example, to be able to attach or screw on a needle.
- the preparation device according to the invention can be inserted into the injection device or is already present in the injection device and preferably has a handle that is easy to grasp in the inserted state and can, for example, be rotated relative to the injection device by a user in order to open the closure of the ampoule.
- the preparation device can be inserted or inserted on the delivery side or into the front of the injection device and protrudes from the injection device, which makes it possible for a user to easily grip the preparation device and, for example, twist it relative to the injection device and thus lock the device
- the ampoule opens and the closure can be removed from the injection device, for example with the preparation device.
- the preparation device can advantageously be, for example, an approximately cylindrical, elongated element which has an outer diameter which is slightly smaller than the inner diameter of a needle guard element or a front side of the injection device.
- the present invention relates to a preparation device or a tool for preparing the injection device, in particular an auto-injection device, wherein the preparation device or the tool has a holding element for a needle, in particular a Luer needle, which has the needle for placement or inserting into the injection device can hold and can release after attaching and / or unscrewing the needle, so that the preparation device can be removed again from the injection device, which thus for carrying out an injection by attaching a needle, for example an open ampoule is prepared.
- a holding element for a needle in particular a Luer needle
- the preparation device thus enables, for example, the insertion or screwing on of a needle in an area, for example protected by a housing or a needle protection element, which is difficult to access inside the injection device, where the needle is connected to the injection device or an ampoule, for example by screwing and for example by holding or connecting the needle to the preparation device withdrawal of the preparation device from the needle connected to the ampoule or injection device can be released.
- the holder of the needle can be a simple receiving element into which the needle is inserted or it can also have detachable holding or connecting elements, such as latches, clamping pieces or clamps.
- the preparation device can be designed such that a needle is already present in the preparation device in the initial state or, alternatively, can be configured such that a needle can be inserted into the preparation device and placed on the injection device with the preparation device.
- the preparation device is advantageously designed such that the needle with a needle protection cap placed thereon can be inserted or inserted into the preparation device, the preparation device preferably being able to hold the needle protection cap, for example, by latching with the needle protection cap after the needle has been inserted into the preparation device that the preparation device can be used to place the needle on the injection device and the preparation device together with the needle protection cap can be removed from the injection device again, thereby exposing the needle for carrying out an injection.
- the preparation device is designed such that it has both the above-mentioned connecting element for connecting the preparation device to an ampoule closure or with an ampoule protective cap, and also the holding element for a needle described above, these two elements, for example for example, about a stabfb 'shaped preparation means are provided at opposite ends, so that the preparation device after opening the ampoule simply by 180 ° can be rotated in order to apply to the opened ampoule a needle.
- the preparation device preferably has a device for limiting a torque which is caused by the rotation of the preparation device by a User for screwing a needle is transferred to the injection device.
- a torque limitation can be realized, for example, by a two-part design of the preparation device, a part of the preparation device which is gripped by a user being connected or coupled to the other part by means of connecting elements, such as cams, in such a way that when exceeded a certain and preferably predeterminable torque, the connection between the two parts of the preparation device is released in such a way that the two parts can rotate relative to one another, so that a torque acting on a first part of the preparation device is only transmitted to the second part up to a certain maximum limit and a higher torque leads, for example, to a further rotation or slipping of the first part relative to the second part, whereby it can be ensured, for example, that a needle only exerts a certain maximum force on the injection volume is unscrewed and no excessive force or torque acts on the injection device, which could lead to damage
- the preparation device is advantageously designed such that the injection device is secured by the preparation device inserted into the injection device, i.e. Triggering of an injection process is prevented by the injection device used and can only be carried out if, for example, an injection needle has been attached to the injection device, for example a securing ring described below can be provided for securing purposes, which preferably is only removed from the injection device with the preparation device can be.
- a securing ring described below can be provided for securing purposes, which preferably is only removed from the injection device with the preparation device can be.
- the invention relates to a locking ring for an injection device, which is arranged, for example, on a delivery side of the injection device and, for example, is plugged onto the injection device and is held by it, for example, by a latching mechanism.
- the circlip can For example, be configured such that it prevents or can prevent displacement of a release element for a triggering process, such as displacement of a trigger sleeve of the injection device, for example relative to a housing or a needle guard, wherein the injection device is designed such that an injection The process can only be triggered or carried out after the trigger sleeve has been moved.
- the locking ring is, for example, placed on the front of the injection device, for example on the trigger sleeve and / or the needle guard, and is connected to the injection device by a releasable connection, such as one or more latching elements.
- the connection between the securing ring and the injection device is preferably designed in such a way that it can be released.
- the connection can particularly preferably be released by the preparation device after a needle has been placed on or inserted into the injection device. It is advantageous to design the connection between the locking ring and the injection device such that the connection can only be released when an injection needle is securely connected to the injection device, for example by inserting the preparation device sufficiently deep into the injection device has been.
- cams or drivers can be provided on the outside of the preparation device, which can release or unlock the securing or connection between the securing ring and the injection device when the preparation device is inserted sufficiently deeply, so that the securing ring can be removed from the injection device.
- the locking ring is advantageously connected to the injection device such that the locking ring can be rotated on or on the injection device, but cannot be axially displaced, as long as the connection between the locking ring and the injection device has not been unlocked or released by, for example, the preparation device.
- the locking ring can be coupled to the injection device, for example by means of grooves, in such a way that rotation of the locking ring can be transmitted to the preparation device inserted through the locking ring into the injection device, so that a user can insert one into the injection device ection device inserted preparation device can rotate with the locking ring in order to play to open the cap of an ampoule or to apply or unscrew an injection needle.
- the securing ring is preferably mounted on the injection device in such a way that it cannot be moved in the axial direction without loosening a connecting or bearing element and an axial displacement of the securing ring, for example for removing the securing ring, is only possible when the corresponding connecting or holding elements for example by the preparation device described above.
- the invention relates to an injection device with a locking ring as described above, wherein the injection device is preferably designed such that the actuation of a release button cannot trigger an injection process as long as the locking ring is on the injection device ,
- the present invention relates to an injection device onto which a needle can be screwed or attached which a needle can be used or which is already connected to a needle and, according to the invention, has a needle protection element which is in a retracted position in an initial state and can be extended or retracted via a needle after an injection process, for example by a spring element, in order to extend after extension to be placed around the needle to prevent accidental contact with the needle.
- the needle protection element can preferably only be extended from a position pushed in to a starting position to secure the needle and can then be secured or locked in the extended or extended position, for example by a latching connection or a latch which securely retracts the needle protection when it is pushed out the extended position to secure the needle.
- a moving needle guard has the advantage that the injection device can be shorter than known injection devices with a retractable needle guard that is pushed out in the initial state.
- the needle guard provided according to the invention and not extended in the initial state enables a shorter triggering path to be carried out with less effort to carry out an injection, since the needle guard does not first have to be pushed back over a longer distance against a force caused by a needle guard spring in order to achieve the Release needle.
- the needle is first extended out of the injection device and then the needle protection element is pushed over the extended needle.
- the needle guard is advantageously mounted on a syringe holder within the injection device and axially limited, for example, by a stop in a front position.
- the needle guard is preferably pressed into the front position by a spring element which is supported on the syringe holder.
- a trigger sleeve is provided coaxially with the needle guard, which protrudes beyond the needle guard and on which, for example, a locking ring described above can be located in order to be able to prevent the trigger sleeve from being accidentally moved.
- the injection device is preferably designed in such a way that a triggering process can only be started or carried out when the trigger sleeve is displaced relative to the needle guard, which can be caused, for example, by pressing the injection device onto an injection site.
- the release sleeve preferably establishes a mechanical connection between a previously freely released release button and a release mechanism after the slide or insertion, for example at the level of the front edge of a needle protection element, so that the release mechanism can only be actuated after the release sleeve has been moved by pressing the release button.
- an automatic triggering process is advantageously carried out, an injection needle being pushed out or ejected forward from the injection device, for example by the force of a spring element, to place it in a tissue, for example.
- a displacement body for example a stopper
- the needle protection element is advantageously biased by a spring element in such a way that it is pressed in the direction of the injection needle and automatically pushes over the injection needle when the injection device is removed from the injection site again.
- the needle protection element on the outside is advantageously colored with an indicator or signal color, such as red, orange, yellow or with another color, so that it can be relatively easily recognized whether the injection device has already been used.
- a locking element such as a catch, is provided, with which the needle guard can be locked or locked in the extended position in order to secure the injection needle, for example, to surround it and thereby to prevent accidental contact with the injection needle as far as possible ,
- FIGS. 1A to 1F show a cross section of an injection device which is prepared with a tool for carrying out an injection
- FIGS. 2A to 2F carry out an injection with an injection device and then secure the injection needle
- Figure 3 shows a known injection device in cross section.
- FIG. 1A shows in cross section an auto-injection device 10 with an ampoule 11, which is closed with a protective cap 8, which consists of a rubber part which closes the ampoule 11 and has a plastic cap which is connected to the ampoule 11 and at the same time contains a thread for a Luer needle.
- the protective cap 8 is firmly connected to the tool or the preparation device 12, which is axially displaceable and rotatably coupled in the locking ring 13. Via grooves or other suitable elements, the tool 12 is connected to the circlip 13, which is rotatably mounted or axially connected on the injection device 10, such that rotation of the circlip 13 is transmitted to the tool 12, thereby breaking a predetermined breaking point of the protective cap 8 and thus the front of the ampoule 11 is opened.
- the tool 12 connected to the protective cap 8 can then be pulled out of the injection device 10, as shown in FIG. 1B.
- the locking ring 13 remains axially connected to the injection device 10.
- a Luer needle 5 with the needle protective cap 6 fitted thereon can be inserted into the tool 12, with locking lugs 12a provided at the insertion opening of the tool 12 preventing the needle protective cap 6 from coming out again Tool 12 can be removed, as shown in Figure 1C.
- the Luer needle 5 can be inserted into the injection device 10 through the locking ring 13 and screwed into an internal thread 11a provided on the ampoule 11, around which the Connect the Luer needle 5 firmly to the front of the ampoule opening.
- the locking ring 13 is coupled to the tool 12, for example via grooves, such that rotation of the locking ring 13 can be transmitted to the tool 12 in order to screw on the Luer needle 5.
- the tool 12 consists of two parts 12.1 and 12.2, which are connected in such a way that only a certain maximum torque can be transferred from one part to the other.
- the connection 12d for example formed by locking lugs, between the two Parts 12.1 and 12.2 are released when a predetermined maximum torque is exceeded and thus causes one part to be rotated relative to the other, thereby ensuring that the needle 5 only has a defined torque below a predeterminable maximum torque, for example by rotating the with the tool 12 coupled locking ring 13 is screwed on, as shown in Fig. ID and 1E.
- the tool 12 can then be removed from the injection device 10 together with the securing ring 13 detached from the injection device 10 by the tool 12, so that the injection device 10, as shown in FIG. 1F, for carrying out an injection with the ampoule 11 open and the needle attached 5 is prepared.
- the needle 5 is placed on the ampoule 11, as shown in FIG. ID, a cam or projection 12C provided outside the tool 12 pushing back the needle guard 1 provided inside the trigger sleeve 4 and thereby one on the outside of the Release sleeve 4 provided cam 4a, which holds the locking ring 13 on the injection device 10, so that this cam 4a can be pressed radially inwards and thus releases the securing of the locking ring 13, so that the locking ring 13 from the release sleeve 4 and thus from the injection device 10 can be removed; see Figures 1E and 1F.
- the locking ring 13 can be removed, for example, by providing preloaded spring elements 13a in the locking ring 13, which press radially inwards and engage in corresponding recesses or recesses 12b on the outside of the tool 12, as a result of which the locking ring 13 is fixed to the tool 12 is connected and is removed when the tool 12 is removed from the injection device 10 together with the tool 12, as shown in FIG. 1F.
- the recesses 12b are advantageously provided on the tool 12 such that the tool 12 is inserted into the injection device 10 at least as far must that the needle 5 is securely attached or fastened before the spring elements 13a of the locking ring 13 can snap into place.
- FIGS. 1F and 2A show the injection device 10 prepared for carrying out the injection process.
- the trigger sleeve 4 is pushed back together with the needle guard 1, as shown in FIG. 2B.
- FIG. 2A shows the injection device 10 after the ampoule 11 has been opened and the needle 5 has been screwed on.
- the trigger sleeve 4 is pushed back in the initial state or by being placed on an injection site until the front end of the trigger sleeve 4 is approximately at the front end of the needle guard 1 is present, as shown in Fig. 2A.
- the trigger sleeve 4 is pushed into the ampoule housing 14 and, by shifting the coupling element 25 shown in FIG.
- the syringe holder 2 is simultaneously pushed into a front position, as a result of which the needle guard spring 19 arranged between the syringe holder 2 and the needle guard 1 is tensioned or compressed.
- the ampoule carrier 18 in the ampoule carrier guide 20 has been pushed so far away that the locking elements 21 lie opposite the recesses or recesses 20a provided on the inside of the ampoule carrier guide 20, as shown in FIG. 2C, the locking elements 21 which are preloaded radially outward become them Recesses 20a of the ampoule carrier guide 20 are pressed, whereby the stopper holder 22 is released and released from the ampoule carrier 18; see Figure 2D.
- the injection spring 23 stretched between the rear end of the ampoule carrier 18 and the stopper holder or plunger 22 can thus relax and push the stopper 24 into the ampoule 11, as shown in FIG. 2D, as a result of which the substance contained in the ampoule 11 is displaced and by the extended one Needle 5 is released.
- the needle guard 1 biased by the tensioned needle guard spring 19 in the direction of the injection needle 5 is pushed forward out of the injection device 10 and pushed over the needle 5, as in FIG. 2E shown, whereby the needle 5 can be secured.
- An inwardly biased ratchet or pawl 4a provided in the release sleeve 4 engages behind a rear stop of the needle guard 1 and thus locks it in the extended position.
- the needle guard can still be pushed in a little when pressure is applied, but without releasing the needle 5 until the trigger sleeve 4 coupled to the needle guard 1 touches an extension of the ampoule carrier feed 20.
- the extended needle guard 1 can be used at the same time as an indicator to indicate that the auto-injection device has already been used and can no longer be used.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Environmental & Geological Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006537030A JP2007509658A (ja) | 2003-11-05 | 2004-10-29 | 自動式注射装置 |
EP04789820A EP1682206A1 (de) | 2003-11-05 | 2004-10-29 | Autoinjektionsvorrichtung |
AU2004286735A AU2004286735B2 (en) | 2003-11-05 | 2004-10-29 | Autoinjection device |
US11/418,731 US20060270984A1 (en) | 2003-11-05 | 2006-05-04 | Automatic injection device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10351599A DE10351599A1 (de) | 2003-11-05 | 2003-11-05 | Autoinjektionsvorrichtung |
DE10351599.2 | 2003-11-05 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/418,731 Continuation US20060270984A1 (en) | 2003-11-05 | 2006-05-04 | Automatic injection device |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005044345A1 true WO2005044345A1 (de) | 2005-05-19 |
Family
ID=34559343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CH2004/000652 WO2005044345A1 (de) | 2003-11-05 | 2004-10-29 | Autoinjektionsvorrichtung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20060270984A1 (de) |
EP (1) | EP1682206A1 (de) |
JP (1) | JP2007509658A (de) |
CN (1) | CN1874811A (de) |
AU (1) | AU2004286735B2 (de) |
DE (1) | DE10351599A1 (de) |
WO (1) | WO2005044345A1 (de) |
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WO2009152542A1 (de) | 2008-06-16 | 2009-12-23 | Pharma Consult Ges.M.B.H. & Co Nfg Kg | Injektionsvorrichtung |
WO2011048223A1 (en) * | 2009-10-23 | 2011-04-28 | Bang & Olufsen Medicom A/S | Auto injector with automatic needle shielding |
US9649441B2 (en) | 2005-04-06 | 2017-05-16 | Cilag Gmbh International | Injection device (bayonet cap removal) |
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Cited By (29)
Publication number | Priority date | Publication date | Assignee | Title |
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US9675757B2 (en) | 2004-05-28 | 2017-06-13 | Cilag Gmbh International | Injection device |
EP1795218A1 (de) * | 2004-05-28 | 2007-06-13 | Cilag GmbH International | Injektionsvorrichtung |
US9895493B2 (en) | 2004-05-28 | 2018-02-20 | Cilag Gmbh International | Injection device |
US9675758B2 (en) | 2004-05-28 | 2017-06-13 | Cilag Gmbh International | Injection device |
US10449303B2 (en) | 2004-11-24 | 2019-10-22 | Shl Medical Ag | Injection device |
US7597685B2 (en) | 2004-11-24 | 2009-10-06 | Shl Group Ab | Injection device |
US10456531B2 (en) | 2004-11-24 | 2019-10-29 | Shl Group Ab | Injection device |
US10449302B2 (en) | 2004-11-24 | 2019-10-22 | Shl Medical Ag | Injection device |
WO2006057604A1 (en) * | 2004-11-24 | 2006-06-01 | Shl Medical Ab | Injection device |
US9649441B2 (en) | 2005-04-06 | 2017-05-16 | Cilag Gmbh International | Injection device (bayonet cap removal) |
US9731080B2 (en) | 2005-04-06 | 2017-08-15 | Cilag Gmbh International | Injection device |
US9770558B2 (en) | 2005-09-27 | 2017-09-26 | Cilag Gmbh International | Auto-injection device with needle protecting cap having outer and inner sleeves |
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US9682194B2 (en) | 2008-06-19 | 2017-06-20 | Cilag Gmbh International | Re-useable auto-injector with filling means |
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RU2638675C2 (ru) * | 2012-06-22 | 2017-12-15 | Лаборатуар Агеттан | Инъекционный узел |
US10799646B2 (en) | 2013-06-11 | 2020-10-13 | Cilag Gmbh International | Injection device |
US10709849B2 (en) | 2013-06-11 | 2020-07-14 | Cilag Gmbh International | Guide for an injection device |
US11123492B2 (en) | 2013-06-11 | 2021-09-21 | Cilag Gmbh International | Injection device |
US11173255B2 (en) | 2013-06-11 | 2021-11-16 | Cilag Gmbh International | Injection device |
Also Published As
Publication number | Publication date |
---|---|
AU2004286735A1 (en) | 2005-05-19 |
AU2004286735B2 (en) | 2008-12-18 |
US20060270984A1 (en) | 2006-11-30 |
EP1682206A1 (de) | 2006-07-26 |
CN1874811A (zh) | 2006-12-06 |
JP2007509658A (ja) | 2007-04-19 |
DE10351599A1 (de) | 2005-06-16 |
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