WO2005030952A1 - Procede d'analyse d'haplotype - Google Patents

Procede d'analyse d'haplotype Download PDF

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Publication number
WO2005030952A1
WO2005030952A1 PCT/JP2004/014784 JP2004014784W WO2005030952A1 WO 2005030952 A1 WO2005030952 A1 WO 2005030952A1 JP 2004014784 W JP2004014784 W JP 2004014784W WO 2005030952 A1 WO2005030952 A1 WO 2005030952A1
Authority
WO
WIPO (PCT)
Prior art keywords
polymorphism
frequency
haplotype
drug
block
Prior art date
Application number
PCT/JP2004/014784
Other languages
English (en)
Japanese (ja)
Inventor
Yusuke Nakamura
Akihiro Sekine
Aritoshi Iida
Susumu Saito
Naoyuki Kamatani
Original Assignee
Riken
Stagen Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riken, Stagen Co., Ltd. filed Critical Riken
Priority to JP2005514327A priority Critical patent/JPWO2005030952A1/ja
Publication of WO2005030952A1 publication Critical patent/WO2005030952A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne un procédé pour analyser un haplotype, comprenant les étapes qui consistent : (a) à détecter des polymorphismes génétiques dans au moins un des gènes liés à des médicaments, qui sont listés dans le tableau 1 et obtenus à partir d'une population de sujets ; (b) sélectionner des polymorphismes communs, par traitement des données détectées ; (c) à construire un bloc haplotype au moyen desdits polymorphismes communs ; (d) à spécifier les polymorphismes communs se trouvant dans le bloc haplotype, et ; (e) à spécifier un polymorphisme étiquette à partir des polymorphismes communs se trouvant dans ledit bloc haplotype.
PCT/JP2004/014784 2003-09-30 2004-09-30 Procede d'analyse d'haplotype WO2005030952A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2005514327A JPWO2005030952A1 (ja) 2003-09-30 2004-09-30 ハプロタイプの解析方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003-342519 2003-09-30
JP2003342519 2003-09-30
JP2004158717 2004-05-28
JP2004-158717 2004-05-28

Publications (1)

Publication Number Publication Date
WO2005030952A1 true WO2005030952A1 (fr) 2005-04-07

Family

ID=34395637

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/014784 WO2005030952A1 (fr) 2003-09-30 2004-09-30 Procede d'analyse d'haplotype

Country Status (2)

Country Link
JP (1) JPWO2005030952A1 (fr)
WO (1) WO2005030952A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502212A (ja) * 2006-09-11 2010-01-28 インジェ・ユニバーシティ・インダストリー−アカデミック・コーポレーション・ファウンデーション シトクロムｐ４５０１ａ２、２ａ６及び２ｄ６、ｐｘｒ及びｕｄｐ−グルクロノシルトランスフェラーゼ１ａ族遺伝子の遺伝型分析のためのｈｔｓｎｐｓ、及びそれを用いた遺伝子多重分析法
US7838656B2 (en) * 2006-11-10 2010-11-23 Canon Kabushiki Kaisha Probe, probe set, probe-immobilized carrier, and genetic testing method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1246114A2 (fr) * 2001-03-30 2002-10-02 Perlegen Sciences, Inc. Procédés d'analyse génomique
WO2003083442A2 (fr) * 2002-03-26 2003-10-09 Perlegen Sciences, Inc. Systemes et procedes de gestion des sciences de la vie

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1246114A2 (fr) * 2001-03-30 2002-10-02 Perlegen Sciences, Inc. Procédés d'analyse génomique
WO2003083442A2 (fr) * 2002-03-26 2003-10-09 Perlegen Sciences, Inc. Systemes et procedes de gestion des sciences de la vie

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MOOSER V. ET AL.: "Cardiovascular pharmacogenetics in the SNP era", JOURNAL OF THROMBOSIS AND HAEMOSTASIS, vol. 1, no. 7, July 2003 (2003-07-01), pages 1398 - 1402, XP002904565 *
SEKINE A. ET AL.: "Construction of SNP databases for prediction of drug side effect", BIOBENCHA, vol. 3, no. 4, July 2003 (2003-07-01), pages 41 - 45, XP002904562 *
ZHANG J. ET AL.: "HapScope: a software system for automated and visual analysis of functionally annotated haplotypes", NUCLEIC ACIDS RES., vol. 30, December 2002 (2002-12-01), pages 5213 - 5221, XP002904563 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502212A (ja) * 2006-09-11 2010-01-28 インジェ・ユニバーシティ・インダストリー−アカデミック・コーポレーション・ファウンデーション シトクロムｐ４５０１ａ２、２ａ６及び２ｄ６、ｐｘｒ及びｕｄｐ−グルクロノシルトランスフェラーゼ１ａ族遺伝子の遺伝型分析のためのｈｔｓｎｐｓ、及びそれを用いた遺伝子多重分析法
JP2013074908A (ja) * 2006-09-11 2013-04-25 Inje Univ Industry-Academic Cooperation Foundation シトクロムＰ２Ｄ６遺伝子の遺伝型分析のためのｈｔＳＮＰｓ、及びそれを用いた遺伝子多重分析法
JP2013074907A (ja) * 2006-09-11 2013-04-25 Inje Univ Industry-Academic Cooperation Foundation シトクロムＰ２Ａ６遺伝子の遺伝型分析のためのｈｔＳＮＰｓ、及びそれを用いた遺伝子多重分析法
US7838656B2 (en) * 2006-11-10 2010-11-23 Canon Kabushiki Kaisha Probe, probe set, probe-immobilized carrier, and genetic testing method

Also Published As

Publication number Publication date
JPWO2005030952A1 (ja) 2006-12-07

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