WO2005012364A3 - Matrice complexe a usage biomedical - Google Patents

Matrice complexe a usage biomedical Download PDF

Info

Publication number
WO2005012364A3
WO2005012364A3 PCT/FR2004/002052 FR2004002052W WO2005012364A3 WO 2005012364 A3 WO2005012364 A3 WO 2005012364A3 FR 2004002052 W FR2004002052 W FR 2004002052W WO 2005012364 A3 WO2005012364 A3 WO 2005012364A3
Authority
WO
WIPO (PCT)
Prior art keywords
polymer
complex matrix
molecular weight
chains
natural origin
Prior art date
Application number
PCT/FR2004/002052
Other languages
English (en)
Other versions
WO2005012364A2 (fr
Inventor
Laurence Hermitte
Olivier Benoit
Original Assignee
Anteis Sa
Laurence Hermitte
Olivier Benoit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anteis Sa, Laurence Hermitte, Olivier Benoit filed Critical Anteis Sa
Priority to JP2006521630A priority Critical patent/JP2007500027A/ja
Priority to BRPI0413086-3A priority patent/BRPI0413086A/pt
Priority to CA002534033A priority patent/CA2534033A1/fr
Priority to EP04786014A priority patent/EP1648942A2/fr
Priority to AU2004261752A priority patent/AU2004261752B2/en
Priority to US10/565,442 priority patent/US20060246137A1/en
Priority to CN2004800216528A priority patent/CN1829743B/zh
Publication of WO2005012364A2 publication Critical patent/WO2005012364A2/fr
Publication of WO2005012364A3 publication Critical patent/WO2005012364A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

L'invention concerne une matrice complexe constituée d'au moins un polymère biocompatible d'origine naturelle, réticulée et sur laquelle sont greffées des petites chaînes de poids moléculaire inférieur à 50 000 Da avec un taux de greffage de 10 à 40 %, ainsi qu'un procédé de préparation d'une matrice biocompatible peu dégradable constituée d'au moins un polymère d'origine naturelle, consistant : d'une part, à greffer de petites chaînes de poids moléculaire inférieur à 10 000 Da, avec un taux de greffage de 10 à 40 %, d'autre part, à réticuler les chaînes principales du polymère entre elles, pour créer une matrice homogène.
PCT/FR2004/002052 2003-07-30 2004-07-30 Matrice complexe a usage biomedical WO2005012364A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2006521630A JP2007500027A (ja) 2003-07-30 2004-07-30 生物医学的な使用のための複合マトリックス
BRPI0413086-3A BRPI0413086A (pt) 2003-07-30 2004-07-30 matriz complexa, utilização da mesma, e processo de preparação de uma matriz biocompatìvel pouco biodegradável
CA002534033A CA2534033A1 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical
EP04786014A EP1648942A2 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical
AU2004261752A AU2004261752B2 (en) 2003-07-30 2004-07-30 Complex matrix for biomedical use
US10/565,442 US20060246137A1 (en) 2003-07-30 2004-07-30 Complex matrix for biomedical use
CN2004800216528A CN1829743B (zh) 2003-07-30 2004-07-30 生物医用的复合基质

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0309401 2003-07-30
FR0309401 2003-07-30

Publications (2)

Publication Number Publication Date
WO2005012364A2 WO2005012364A2 (fr) 2005-02-10
WO2005012364A3 true WO2005012364A3 (fr) 2005-06-02

Family

ID=34112706

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/002052 WO2005012364A2 (fr) 2003-07-30 2004-07-30 Matrice complexe a usage biomedical

Country Status (10)

Country Link
US (1) US20060246137A1 (fr)
EP (1) EP1648942A2 (fr)
JP (1) JP2007500027A (fr)
KR (1) KR20070012306A (fr)
CN (1) CN1829743B (fr)
AU (1) AU2004261752B2 (fr)
BR (1) BRPI0413086A (fr)
CA (1) CA2534033A1 (fr)
RU (1) RU2360928C2 (fr)
WO (1) WO2005012364A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
EP2181655B1 (fr) 2002-08-28 2016-12-07 Apollo Endosurgery, Inc. Dispositif de cerclage gastrique résistant à l'usure
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
PT1706044E (pt) 2004-01-23 2011-12-09 Allergan Inc Banda gástrica regulável de uma só peça, que pode ser fixada de forma amovível
AU2005221413B2 (en) 2004-03-08 2010-09-23 Endoart S.A. Closure system for tubular organs
CA2569043C (fr) 2004-03-18 2010-08-17 Allergan, Inc. Appareil et procede de reglage du volume de ballons intragastriques
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
EP1991517B1 (fr) 2006-03-08 2012-11-14 PURAC Biochem BV Procédé de préparation d'un complexe acide lactique-amine organique
FR2909285A1 (fr) * 2006-12-01 2008-06-06 Anteis Sa "utilisation d'un gel anti-adhesif et anti fibrotique"
BRPI0811784A2 (pt) 2007-05-23 2011-05-10 Allergan Inc colÁgeno reticulado e uso do mesmo
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) * 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
EP2818184B1 (fr) 2007-11-16 2018-10-31 Allergan, Inc. Compositions Et Procédés De Traitement Du Purpura
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8574629B2 (en) 2008-08-01 2013-11-05 Anteis S.A. Injectable hydrogel with an enhanced remanence and with an enhanced ability to create volume
AU2015252122A1 (en) * 2008-08-04 2015-11-26 Allergan Industrie Sas Hyaluronic acid-based gels including anesthetic agents
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
WO2010042493A1 (fr) 2008-10-06 2010-04-15 Allergan, Inc. Bande gastrique mécanique avec coussins
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
FR2938187B1 (fr) * 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
EP2236523B1 (fr) * 2009-03-30 2018-02-21 Scivision Biotech Inc. Procédé de production d'acide hyaluronique réticulé
US9371402B2 (en) 2009-04-09 2016-06-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
US8390326B2 (en) * 2009-05-05 2013-03-05 William Marsh Rice University Method for fabrication of a semiconductor element and structure thereof
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
NZ602405A (en) 2010-03-12 2014-12-24 Allergan Ind Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin conditions
DK2550027T4 (da) 2010-03-22 2019-05-13 Allergan Inc Tværbundne polysaccharid- og protein-polysaccharid-hydrogeler til blødvævsforøgelse
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
EP2714002B1 (fr) 2011-06-03 2019-04-03 Allergan, Inc. Compositions de remplissage dermique comprenant des antioxydants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
TWI466675B (zh) 2011-09-16 2015-01-01 Univ China Medical 用於抑制發炎之醫藥組合物
FR2983483B1 (fr) 2011-12-02 2014-11-14 Vivacy Lab Procede de substitution et reticulation simultanees d'un polysaccharide via ses fonctions hydroxyles
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
CN102863631B (zh) * 2012-09-29 2013-11-13 杭州嘉伟生物制品有限公司 外科整形用组织填充剂交联透明质酸钠凝胶及其制备方法
EP3049055B1 (fr) 2013-09-27 2018-04-25 Anteis S.A. Procédé d'obtention d'un hydrogel injectable à base d'aide hyaluronique contenant de la lidocaïne ajoutée sous forme pulvérulente, et un agent alcalin, stérilisé par la chaleur
CZ308492B6 (cs) * 2013-10-25 2020-09-23 Contipro A.S. Kosmetická kompozice na bázi kyseliny hyaluronové, způsob její přípravy a použití
WO2015181369A1 (fr) * 2014-05-29 2015-12-03 Galderma S.A. Acide hyaluronique réticulé greffé à du dextrane
ES2761558T3 (es) 2014-09-30 2020-05-20 Allergan Ind Sas Composiciones de hidrogel estables que incluyen aditivos
EP3040348A1 (fr) 2014-12-29 2016-07-06 Galderma S.A. Copolymère greffé
WO2016128783A1 (fr) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions et méthodes pour améliorer l'apparence de la peau
CZ306662B6 (cs) * 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
KR20180027126A (ko) 2016-09-06 2018-03-14 (주)한국비엠아이 가교화 히알루론산 유도체 매트릭스가 포함된 지혈 조성물

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
WO1987007898A1 (fr) * 1986-06-18 1987-12-30 Pharmacia Ab Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides
EP0265116A2 (fr) * 1986-10-13 1988-04-27 FIDIA S.p.A. Esters réticulés d'acide hyaluronique
EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
EP0749982A1 (fr) * 1995-06-22 1996-12-27 Hercules Incorporated Polysaccharides greffés avec des antioxydants et leurs utilisation
EP0939086A1 (fr) * 1998-02-27 1999-09-01 Stichting Hippomedics Procédé pour préparer un acide hyaluronique réticulé
WO2000046252A1 (fr) * 1999-02-05 2000-08-10 Vitrolife Uk Limited Procede de reticulation d'acide hyaluronique avec des polymeres
WO2002006350A1 (fr) * 2000-07-19 2002-01-24 Laboratoires D'esthetique Appliquee Reticulation de polysaccharide(s), preparation d'hydrogel(s), polysaccharide(s) et hydrogel(s) obtenu(s), leurs utilisations.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4582865A (en) * 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
JPH01265970A (ja) * 1988-04-19 1989-10-24 Shiseido Co Ltd ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液
DE3841401A1 (de) * 1988-12-08 1990-06-13 Martin Lemperle Alloplastisches implantat
US7060287B1 (en) * 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US5451406A (en) * 1994-07-14 1995-09-19 Advanced Uroscience, Inc. Tissue injectable composition and method of use
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US5792478A (en) * 1996-07-08 1998-08-11 Advanced Uro Science Tissue injectable composition and method of use
US20020025340A1 (en) * 2000-08-30 2002-02-28 Dyer Wallace K. Methods and compositions for tissue augmentation
EP1478406B1 (fr) * 2002-02-27 2011-01-05 PharmaIN Corporation Compositions pour l'administration de substances therapeutiques et analogues, et procedes de fabrication et d'utilisation desdites compositions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
WO1987007898A1 (fr) * 1986-06-18 1987-12-30 Pharmacia Ab Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides
US4963666A (en) * 1986-06-18 1990-10-16 Pharmacia Ab Material of polysaccharides containing carboxyl groups, and a process for producing such polysaccharides
EP0265116A2 (fr) * 1986-10-13 1988-04-27 FIDIA S.p.A. Esters réticulés d'acide hyaluronique
EP0341745A1 (fr) * 1988-05-13 1989-11-15 FIDIA S.p.A. Polysaccharides carboxylés réticulés
EP0749982A1 (fr) * 1995-06-22 1996-12-27 Hercules Incorporated Polysaccharides greffés avec des antioxydants et leurs utilisation
EP0939086A1 (fr) * 1998-02-27 1999-09-01 Stichting Hippomedics Procédé pour préparer un acide hyaluronique réticulé
WO2000046252A1 (fr) * 1999-02-05 2000-08-10 Vitrolife Uk Limited Procede de reticulation d'acide hyaluronique avec des polymeres
WO2002006350A1 (fr) * 2000-07-19 2002-01-24 Laboratoires D'esthetique Appliquee Reticulation de polysaccharide(s), preparation d'hydrogel(s), polysaccharide(s) et hydrogel(s) obtenu(s), leurs utilisations.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9228027B2 (en) 2008-09-02 2016-01-05 Allergan Holdings France S.A.S. Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof

Also Published As

Publication number Publication date
CN1829743A (zh) 2006-09-06
CN1829743B (zh) 2010-06-30
RU2006102198A (ru) 2007-08-20
WO2005012364A2 (fr) 2005-02-10
JP2007500027A (ja) 2007-01-11
AU2004261752A1 (en) 2005-02-10
US20060246137A1 (en) 2006-11-02
CA2534033A1 (fr) 2005-02-10
EP1648942A2 (fr) 2006-04-26
KR20070012306A (ko) 2007-01-25
RU2360928C2 (ru) 2009-07-10
BRPI0413086A (pt) 2006-10-03
AU2004261752B2 (en) 2010-10-28

Similar Documents

Publication Publication Date Title
WO2005012364A3 (fr) Matrice complexe a usage biomedical
WO2007109069A3 (fr) Dérivés hydrophobes de polysaccharides biodégradables et utilisations de ceux-ci
EP3449946A3 (fr) Compositions de support à noyau hydrophobe pour l'administration d'agents thérapeutiques, procédés de fabrication et d'utilisation de celles-ci
CA2266581A1 (fr) Polymeres contenant des polyosides tels que des alginates ou des alginates modifies
UA100378C2 (uk) Полімерна композиція, спосіб її виготовлення, виріб, спосіб його виготовлення та спосіб формування, застосування, спосіб підвищення швидкості текучості розплаву суміші та спосіб зменшення технологічного циклу формування виробу
WO2006004941A3 (fr) Biomateriel
WO2007064881A3 (fr) Materiaux en cellulose microbienne implantables pour diverses applications medicales
WO2006125082A3 (fr) Hydrogels et particules d'hydrogel
WO2003042264A3 (fr) Polymeres greffes dont les chaines laterales comprennent des heterocycles azotes
WO2004039248A3 (fr) Reparation ou remplacement de tissus ou d'organes
AU4360301A (en) Tissue bulking and coating compositions
MX2007005724A (es) Articulo para tratamiento cosmetico que comprende un sustrato y una composicion en gel.
WO2005040230A3 (fr) Nouveau latex inverse concentre, procede pour sa preparation, et utilisation dans l'industrie
WO2006076326A3 (fr) Implants vasculaires et procedes d'elaboration
WO2005107828A3 (fr) Articles médicaux inserables ou implantables ayant des surfaces biocompatibles modifiees covalentes
WO2003042262A3 (fr) Polymeres greffes dont les chaines laterales comprennent des heterocycles azotes
CA2375685A1 (fr) Compositions a base de melange compatible de polyurethanne-polyolefine thermoplastique
TW200714617A (en) Graft copolymer and method for preparing the same
WO2004004598A3 (fr) Rapamycines polymerisees et modifiees et utilisation de celles-ci dans le revetement de protheses medicales
EP2223946A3 (fr) Caoutchouc naturel modifié ou latex en caoutchouc naturel modifié et composition en caoutchouc
WO2006047841A3 (fr) Reconstruction de tissus d'echafaudage
WO2003087165A3 (fr) Materiaux et sondes biocompatibles
JP2002519462A5 (fr)
WO2004044222A3 (fr) Promedicaments polymeres de la vancomycine
MXPA05006414A (es) Poliazoles de alto peso molecular.

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200480021652.8

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004786014

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2534033

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2006102198

Country of ref document: RU

Ref document number: PA/a/2006/001060

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2004261752

Country of ref document: AU

Ref document number: 1020067002010

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2006521630

Country of ref document: JP

ENP Entry into the national phase

Ref document number: 2004261752

Country of ref document: AU

Date of ref document: 20040730

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004261752

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004786014

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2006246137

Country of ref document: US

Ref document number: 10565442

Country of ref document: US

ENP Entry into the national phase

Ref document number: PI0413086

Country of ref document: BR

WWP Wipo information: published in national office

Ref document number: 10565442

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 1020067002010

Country of ref document: KR