WO2002088095A1 - Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) - Google Patents

Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) Download PDF

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Publication number
WO2002088095A1
WO2002088095A1 PCT/GB2002/002029 GB0202029W WO02088095A1 WO 2002088095 A1 WO2002088095 A1 WO 2002088095A1 GB 0202029 W GB0202029 W GB 0202029W WO 02088095 A1 WO02088095 A1 WO 02088095A1
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WO
WIPO (PCT)
Prior art keywords
methyl
dihydro
pyrrolo
dichlorophenyl
compounds
Prior art date
Application number
PCT/GB2002/002029
Other languages
English (en)
French (fr)
Inventor
Anna Maria Capelli
Romano Di Fabio
Chiara Marchionni
Fabrizio Micheli
Alessandra Pasquarello
Benedetta Perini
Yves St-Denis
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0110570A external-priority patent/GB0110570D0/en
Priority claimed from GB0110567A external-priority patent/GB0110567D0/en
Priority claimed from GB0110569A external-priority patent/GB0110569D0/en
Priority claimed from GB0117399A external-priority patent/GB0117399D0/en
Priority claimed from GB0117420A external-priority patent/GB0117420D0/en
Priority claimed from GB0117401A external-priority patent/GB0117401D0/en
Priority claimed from GB0203201A external-priority patent/GB0203201D0/en
Priority claimed from GB0206834A external-priority patent/GB0206834D0/en
Priority to AU2002253357A priority Critical patent/AU2002253357B2/en
Priority to HU0304054A priority patent/HUP0304054A2/hu
Priority to DE60225127T priority patent/DE60225127T2/de
Priority to JP2002585397A priority patent/JP2004528349A/ja
Priority to EP02722478A priority patent/EP1383747B1/en
Priority to US10/476,368 priority patent/US7279474B2/en
Priority to KR10-2003-7014160A priority patent/KR20040015206A/ko
Priority to BR0209267-0A priority patent/BR0209267A/pt
Priority to ES02722478T priority patent/ES2301633T3/es
Priority to MXPA03009938A priority patent/MXPA03009938A/es
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Priority to IL15806202A priority patent/IL158062A0/xx
Priority to CA002446514A priority patent/CA2446514A1/en
Publication of WO2002088095A1 publication Critical patent/WO2002088095A1/en
Priority to NO20034836A priority patent/NO20034836L/no

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PCT/GB2002/002029 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) WO2002088095A1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
US10/476,368 US7279474B2 (en) 2001-04-30 2002-04-30 Substituted pyrrolo[2,3-d]pyrimidines as antagonists of the corticotropin releasing factor (CRF)
KR10-2003-7014160A KR20040015206A (ko) 2001-04-30 2002-04-30 코르티코트로핀 방출 인자 (ｃｒｆ)의 길항제로서의 접합피리미딘
CA002446514A CA2446514A1 (en) 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)
IL15806202A IL158062A0 (en) 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)
AU2002253357A AU2002253357B2 (en) 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)
MXPA03009938A MXPA03009938A (es) 2001-04-30 2002-04-30 Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina.
ES02722478T ES2301633T3 (es) 2001-04-30 2002-04-30 Pirimidinas condensadas como antagonistas del factor de liberacion de corticotropina (crf).
HU0304054A HUP0304054A2 (hu) 2001-04-30 2002-04-30 A kortikotropin-realising faktor (CRF) antagonistáiként alkalmazható kondenzált pirimidinek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
BR0209267-0A BR0209267A (pt) 2001-04-30 2002-04-30 Pirimidinas fundidas como antagonistas do fator de liberação de corticotropina (crf)
DE60225127T DE60225127T2 (de) 2001-04-30 2002-04-30 Kondensierte pyrimidine als antagonisten des corticotropin releasing factor (crf)
JP2002585397A JP2004528349A (ja) 2001-04-30 2002-04-30 副腎皮質刺激ホルモン放出因子（ｃｒｆ）のアンタゴニストとしての縮合ピリミジン類
EP02722478A EP1383747B1 (en) 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)
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DE60225127D1 (en) 2008-04-03
CN1649848A (zh) 2005-08-03
CZ20032946A3 (en) 2004-05-12
DE60225127T2 (de) 2009-02-19
BR0209267A (pt) 2004-06-15
US7279474B2 (en) 2007-10-09
JP2004528349A (ja) 2004-09-16
EP1383747B1 (en) 2008-02-20
US20040176400A1 (en) 2004-09-09

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