WO2002072444A1 - Bouchon de dosage au goutte par goutte destine au dosage de liquides sous forme de gouttes et contenant comportant un tel bouchon - Google Patents

Bouchon de dosage au goutte par goutte destine au dosage de liquides sous forme de gouttes et contenant comportant un tel bouchon Download PDF

Info

Publication number
WO2002072444A1
WO2002072444A1 PCT/EP2002/001919 EP0201919W WO02072444A1 WO 2002072444 A1 WO2002072444 A1 WO 2002072444A1 EP 0201919 W EP0201919 W EP 0201919W WO 02072444 A1 WO02072444 A1 WO 02072444A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
outlet channel
throttle device
drip cap
inlet opening
Prior art date
Application number
PCT/EP2002/001919
Other languages
German (de)
English (en)
Inventor
Heino Deussen
Original Assignee
Stella Kunststofftechnik Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stella Kunststofftechnik Gmbh filed Critical Stella Kunststofftechnik Gmbh
Priority to AT02716808T priority Critical patent/ATE287365T1/de
Priority to EP02716808A priority patent/EP1368245B1/fr
Priority to DE50202047T priority patent/DE50202047D1/de
Priority to JP2002571374A priority patent/JP2004529827A/ja
Publication of WO2002072444A1 publication Critical patent/WO2002072444A1/fr
Priority to US10/661,801 priority patent/US20040050881A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers

Definitions

  • the invention relates to a drip cap for dosing liquid in drop form from a container, the contents of which can be put under pressure for dosing, with a cap body in which an outlet channel and a throttle device are arranged.
  • the invention also relates to a container with a drip cap.
  • Medicines that are used in liquid form are provided in tubes or vials, from which they are dosed in drops. Since the medication is linked to the number of drops, it is crucial that the drop volume during dosing is always constant and cannot be influenced by the user.
  • the drip insert has an air channel in addition to the outlet channel, through which air can flow into the interior of the vial when it is being dosed.
  • the drop cap In the case of bottles or tubes made of flexible plastic material, the drop cap has only one outlet channel through which the liquid is metered out by pressure on the container wall. It is important that the outlet channel defines the drop size exactly.
  • Such a drip tip for eye drops is used, for example, in the EP 0 431 885 AI described.
  • the outlet channel has an inlet opening, the cross section of which is smaller than that of the outlet opening, the size of the outlet opening essentially determining the drop size. Extensive tests have been carried out to determine the optimum dimensions in order to prevent the liquid from escaping as a jet instead of as drops if the user exerts excessive pressure on the container wall. It has been found here that in addition to the conical shape of the outlet channel, the outer shape of the drip tip is particularly important when the container is held at an angle.
  • EP 0 956 904 AI describes a drip insert that can be inserted into a container. This dropper insert should always deliver constant droplet sizes regardless of the pressure on the liquid. Starting from an outlet channel with an inlet opening that is smaller than the outlet opening, not only conical outlet channels but also those with cylindrical sections are proposed.
  • the pressure at which the throttle device opens depends essentially on the elastic properties of the container material, so that different pressures have to be applied to different materials, to which the operator has to adjust each time. It is therefore desirable that metering with a constant droplet size is made possible, which is independent of the selected container material.
  • the object is achieved with a drip cap for dosing liquids in the form of drops, in which the throttle device is arranged in the flow direction in front of the inlet opening of the outlet channel.
  • the pressure exerted by the user on the liquid must not propagate into the outlet channel, but must be reduced in front of the outlet channel to such an extent that the pressure conditions in the area of the outlet channel allow drops to form.
  • the throttle device arranged in front of the inlet opening allows the maximum pressure which acts on the liquid to be metered in before or in the outlet channel to be set. The throttle device ensures, even at high pressure exerted on the liquid, that constant pressure conditions are always maintained in the outlet channel.
  • the throttle device is preferably arranged at a distance from the inlet opening of the outlet channel. Since at high pressures exerted on the liquid the liquid passes through the throttle device at high flow velocity, the liquid could penetrate directly into the inlet opening, the jet continuing in the outlet channel, which could prevent the formation of constant droplet sizes.
  • the spaced arrangement of the throttling device ensures that the liquid flowing through the throttling device can first distribute itself before it reaches the inlet opening.
  • the intermediate chamber has the advantage that the liquid can first collect here before it penetrates into the inlet opening of the outlet channel.
  • the volume of the intermediate chamber is preferably greater than / equal to the volume of the outlet channel. This ensures that the entire volume required for a drop is made available in the intermediate chamber under suitable pressure.
  • the intermediate chamber is preferably delimited by the cap body and a chamber wall.
  • the throttle device is preferably arranged in the chamber wall.
  • the throttle device can comprise at least one passage opening in the chamber wall, the cross section of which is smaller than the cross section of the inlet opening of the outlet channel.
  • Other throttling devices such as valve flaps or the like can also be used.
  • the passage opening can be opposite the inlet opening. However, it is advantageous if the passage opening is arranged offset to the inlet opening because the liquid jet formed through the passage opening first undergoes a deflection and thus a further reduction in pressure.
  • the chamber wall preferably consists of an annular wall and a partition.
  • the ring wall can be adapted to the dimensions of the cap body.
  • the throttle device is preferably arranged in the partition.
  • the chamber wall is preferably molded onto the cap body.
  • the drip cap and container can be combined in different ways.
  • the drip cap according to the invention can be an integral part of the container.
  • the container and the drip cap will be manufactured separately and then the drip cap will be inserted into the container neck or into the pouring opening of the container.
  • the drop cap according to the invention is made available as an insert which is inserted into the container neck of any conventional container.
  • the container in the pouring opening can have a conventional drip cap in the outlet channel.
  • the throttle device is arranged in a partition wall of the container, this partition wall being arranged at a distance from the drip cap in the interior of the container.
  • the partition is preferably arranged in the neck of the container.
  • the partition is preferably arranged perpendicular to the container axis.
  • the partition can be inserted into the container or can be an integral part of the container.
  • the throttle device is preferably arranged in this partition.
  • the throttle device comprises at least one passage opening, the cross section of which is smaller than the cross section of the inlet opening of the outlet channel. By selecting the cross section of this opening, the maximum pressure acting on the outlet channel can be set. This ensures that the liquid to be dosed enters the outlet channel under the same pressure, so that there can be no influence on the pressure exerted by the user on the drop shape.
  • the passage opening is preferably opposite the inlet opening.
  • the passage opening is preferably arranged offset to the inlet opening.
  • the volume of the intermediate space between the drip cap and the dividing wall is preferably greater than or equal to the volume of the outlet channel.
  • the conventional container or the container according to the invention preferably has a flexible container wall, which can be made of plastic, for example.
  • the container can be a tube, a vial, or other suitable container.
  • the flexible container wall makes it possible, for example, to pressurize the contents of the container by hand and thus be able to perform the dosing.
  • a pressure device can also be provided on or in the container or the container can be connectable to a pressure device.
  • a pressure device would be, for example, a pump mechanism with the Air is pressed into the interior of the container so that the liquid is pressed through the throttle device.
  • the drip cap can be used in the container neck in a liquid-tight or pressure-tight manner. It is possible, for example, to create a tight connection with the container by welding the drip cap.
  • FIG. 1 shows a vertical section through a container with an inserted
  • Figure 2 shows a vertical section through a container with an inserted
  • FIG 3 shows a vertical section through a container according to the invention with a conventional drip cap.
  • FIG. 1 the area of the container neck 3 of a container 1 is shown in vertical section.
  • the container wall 2, which delimits the interior 6 of the container 1, is only shown in part in order to be able to enlarge the drip cap 10 arranged in the container neck 3 or the pouring opening.
  • An external thread 4 is formed on the outside of the container neck 3 so that a closure cap (not shown) can be applied to the container neck 3.
  • the container neck 3 is cylindrical and is used for Receiving the drip cap 10, which has a substantially cup-shaped cap body 11 with a bottom wall 13 and a peripheral wall 14.
  • the cap body 11 has a metering nozzle 12 in the center, in which an outlet channel 20 is arranged.
  • the metering nozzle 12 extends vertically upward from the horizontally arranged bottom wall 13 and projects beyond the circumferential wall 14, which has an annular flange 15 at its upper end, with which the drip cap 10 rests on the end face of the container neck 3 and can be fastened there.
  • the outer diameter of the peripheral wall 14 corresponds to the inner diameter of the container neck 3, so that the drip cap 10 can be inserted into the container neck 3 in a liquid-tight manner.
  • the outlet channel 20 has at the lower end, i.e. in the area of the bottom wall 13 there is an inlet opening 21 with a small diameter, the diameter being smaller than the diameter of the outlet opening 25 at the upper end of the metering nozzle 12.
  • the inlet opening 21 is followed by a cylindrical inlet section 22 which merges into a conical section 23 , which widens in the direction of the outlet opening 25.
  • the conical section 23 is followed by a cylindrical section 24, which forms the outlet opening 25.
  • the diameter of the outlet opening 25 can be, for example, in the range between 5 and 10 mm.
  • the cross section of the outlet opening 25 defines the drop size.
  • the outlet channel 23 can also have other cross-sectional shapes, as is shown and described for example in EP 0956904 AI. It is not imperative here that the inlet opening has a smaller cross section than the outlet opening. Depending on the type of liquid, drops with a cylindrical outlet channel can also be generated.
  • a chamber wall 32 which delimits an intermediate chamber 35, is integrally formed on the bottom wall 13. In the embodiment shown here, the chamber wall 32 consists of an annular wall 33, the outer diameter of which corresponds to the inner diameter of the container shark 3, and a partition wall 34 oriented perpendicular to the container axis.
  • a throttle device 30 in the form of a passage opening 31 is arranged in the middle of the partition wall 34, the cross section of which is smaller than the cross section of the inlet opening 21.
  • the chamber wall 32 is an integral part of the drip cap 10, which extends with the intermediate chamber 35 over the entire length of the container neck 3.
  • the intermediate chamber 35 can also protrude into the interior 6 of the container.
  • the volume of the intermediate chamber 35 is greater than the volume of the outlet channel 20.
  • FIG. 2 shows a further embodiment in which the container neck 3 is shorter than is the case with the container 1 according to FIG. 1.
  • the intermediate chamber 35 is also cylindrical, although the volume of the intermediate chamber 35 is smaller than in the embodiment according to FIG. 1. In this embodiment too, the volume of the intermediate chamber 35 is greater than the volume of the outlet channel 20.
  • the passage opening 31 is arranged off-center and is thus offset from the inlet opening 21 of the outlet channel 20. This is advantageous in this embodiment because the distance of the partition wall 34 to the inlet opening 21 is significantly less than in the embodiment according to FIG. 1, so that the inflow flows directly over it 10
  • the container wall 2 consists of flexible material, so that the liquid to be dosed can be pressed through the passage opening 31 into the intermediate chamber 35 and thus into the outlet channel 20 by compressing the container wall 2.
  • FIG. 3 A further embodiment is shown in FIG. 3, the innovation relating to the container 1 '.
  • the drip cap has no chamber wall, as shown in Figures 1 and 2, but consists of an essentially conventional drip cap 10 ', which is inserted into the container neck 3.
  • a partition wall 34 ' is drawn in in the lower region of the container neck 3, which has the throttle device 30 off-center in the form of a passage opening 31.
  • the intermediate chamber 35 ' is located between the partition 34' and the bottom wall 13 of the drip cap 10 '.
  • the throttle device 30 is therefore part of the container and not part of the drip cap 10 '.
  • the inventive design of the container 1 makes it possible to use conventional drip caps 10 '.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)

Abstract

L'invention concerne un bouchon de dosage au goutte par goutte (10) destiné au dosage de liquides sous forme de gouttes à partir d'un contenant (1) dont le contenu peut être mis sous pression. L'invention vise à conserver précisément le volume de dosage prédéfini, notamment dans le cas de grandes gouttes, ledit volume devant être indépendant de la pression exercée sur le liquide. A cet effet, un système d'étranglement (30) est disposé dans le sens d'écoulement, en amont de l'ouverture d'entrée (21) du canal de sortie (20) logé dans le corps de bouchon (11). Ledit système d'étranglement (30) peut être conçu en tant qu'ouverture de passage (31) dans une paroi de séparation supplémentaire (34). L'invention concerne également un contenant (1, 1') comportant un tel bouchon de dosage (10, 10').
PCT/EP2002/001919 2001-03-13 2002-02-23 Bouchon de dosage au goutte par goutte destine au dosage de liquides sous forme de gouttes et contenant comportant un tel bouchon WO2002072444A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AT02716808T ATE287365T1 (de) 2001-03-13 2002-02-23 Tropfkappe zum ausdosieren von flüssigkeit in tropfenform und behälter mit tropfkappe
EP02716808A EP1368245B1 (fr) 2001-03-13 2002-02-23 Bouchon de dosage au goutte par goutte destine au dosage de liquides sous forme de gouttes et contenant comportant un tel bouchon
DE50202047T DE50202047D1 (de) 2001-03-13 2002-02-23 Tropfkappe zum ausdosieren von flüssigkeit in tropfenform und behälter mit tropfkappe
JP2002571374A JP2004529827A (ja) 2001-03-13 2002-02-23 滴状の液体を吐出するためのドロッパキャップ並びにドロッパキャップを有するコンテナ
US10/661,801 US20040050881A1 (en) 2001-03-13 2003-09-12 Drop cap for dosing the amount of liquid in a drop and container comprising a drop lid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10112332.9 2001-03-13
DE10112332A DE10112332C1 (de) 2001-03-13 2001-03-13 Tropfkappe zum Ausdosieren von Flüssigkeit in Tropfenform und Behälter mit Tropfkappe

Publications (1)

Publication Number Publication Date
WO2002072444A1 true WO2002072444A1 (fr) 2002-09-19

Family

ID=7677477

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001919 WO2002072444A1 (fr) 2001-03-13 2002-02-23 Bouchon de dosage au goutte par goutte destine au dosage de liquides sous forme de gouttes et contenant comportant un tel bouchon

Country Status (7)

Country Link
US (1) US20040050881A1 (fr)
EP (1) EP1368245B1 (fr)
JP (1) JP2004529827A (fr)
AT (1) ATE287365T1 (fr)
DE (2) DE10112332C1 (fr)
ES (1) ES2235020T3 (fr)
WO (1) WO2002072444A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069679A1 (fr) * 2003-02-07 2004-08-19 Hoffmann Neopac Ag Distributeur goutte a goutte a insert pour optimiser la precision de dosage de liquides

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003202757A1 (en) * 2003-02-07 2004-08-30 Hoffmann Neopac Ag Drop-dispensing insert with laser bore
DE102006005608B4 (de) * 2006-02-06 2007-10-11 Heraeus Kulzer Gmbh Dentalbehältnis mit verdampfungsdicht verschließbarem Tropfereinsatz
US20080039807A1 (en) * 2006-08-08 2008-02-14 Jerrold Scott Pine Ophthalmic Drug Dispensing Tip
JP4913499B2 (ja) * 2006-08-09 2012-04-11 伸晃化学株式会社 薬液容器の中栓
DE102008001313B9 (de) * 2008-04-22 2009-11-12 Stella Kunststofftechnik Gmbh Tropfkappe
DE102008034831A1 (de) * 2008-07-26 2010-01-28 Brämig, Sabine Flaschendosierer
US8490786B2 (en) * 2009-02-11 2013-07-23 Liquid Health Labs, Inc. Inverted dome to supply dose
CA2779691A1 (fr) 2009-11-05 2011-05-12 Liquid Health Labs, Inc. Fermeture bombee universelle pour distribuer une dose
WO2011106539A1 (fr) * 2010-02-24 2011-09-01 Colgate-Palmolive Company Couvercle distributeur comprenant des réservoirs sélectionnables
DE102010023641A1 (de) 2010-06-14 2011-12-15 Hoffmann Dental Manufaktur Gmbh Kit zur Zementierung auf Zahnimplantaten
DE202010009036U1 (de) 2010-06-14 2010-10-07 Hoffmann Dental Manufaktur Gmbh Kit zur Zementierung auf Zahnimplantaten
EP2597044A1 (fr) 2011-11-25 2013-05-29 Hoffmann Neopac AG Insert compte-gouttes et récipient avec insert compte-gouttes
US10667943B2 (en) * 2012-03-13 2020-06-02 Ben Z. Cohen Nozzle
US20150129619A1 (en) * 2013-11-08 2015-05-14 Pheneo Gmbh Dropper for dispensing drops of a fluid, dropper-cap system and container with such a dropper or dropper-cap system
KR101554189B1 (ko) * 2013-12-10 2015-09-21 (주)연우 액상 내용물을 방울 형태로 배출시키는 튜브형 화장품 용기
JP6255293B2 (ja) * 2014-03-31 2017-12-27 株式会社吉野工業所 吐出部材
EP3034428B1 (fr) * 2014-12-19 2017-07-19 SHB GmbH Bouchon de dosage pour un flacon de dosage
PE20160759A1 (es) * 2015-06-09 2016-07-28 Gonzalez Sierra Andres Fernando Sistema dosificador mejorado
CH712432A1 (de) * 2016-05-03 2017-11-15 Hoffmann Neopac Ag Tube mit Drosseleinsatz.
US10723526B1 (en) 2019-03-29 2020-07-28 Chubby Gorilla, Inc. Bottle and cap arrangement
KR102076658B1 (ko) * 2019-05-31 2020-02-13 임종수 튜브용기 내의 액상 내용물을 방울 형태로 배출시키는 배출장치
KR102279627B1 (ko) * 2021-03-02 2021-07-21 한국콜마주식회사 내용물 용기

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US2800253A (en) * 1952-10-07 1957-07-23 Henderson Edward Drop dispenser and container
DE1063755B (de) * 1954-10-25 1959-08-20 Sattler Atlan Werk Kg L Kunststofftropfflasche
US3189223A (en) * 1964-05-18 1965-06-15 Halkey Roberts Corp Liquid dispensing device
DE2215337A1 (de) * 1972-03-29 1973-10-11 Hans Heinlein Dichtungsanordnung fuer flascheneinsaetze
EP0114007A1 (fr) * 1983-01-13 1984-07-25 L'oreal Récipient permettant de distribuer goutte à goutte une dose de substance fluide
EP0431885A1 (fr) 1989-12-08 1991-06-12 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Embout compte-gouttes pour distribuer un produit liquide, notamment collyres
US5356052A (en) 1993-10-13 1994-10-18 Healthstar Inc. BFS metered drop bottle
EP0956904A1 (fr) 1998-05-14 1999-11-17 Lameplast S.R.L. Buse pour délivrer des gouttes de liquide
WO2002038464A1 (fr) * 2000-11-13 2002-05-16 Laboratoires Thea Distributeur de liquides goutte a goutte

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US3777939A (en) * 1971-09-15 1973-12-11 H Moore Paint tube dispensing cap
US5226568A (en) * 1992-01-13 1993-07-13 Blairex Laboratories Inc. Flexible container for storage and dispensing of sterile solutions
US5373964A (en) * 1993-06-23 1994-12-20 Moore; Sidney D. Eyedrop dispenser with focusing liquid lens
ATE168553T1 (de) * 1993-06-25 1998-08-15 Alcon Cusi S A Neue verwendung von polymeren membranen zum ausgeben von pharmazeutischen lösungen, die quarternäre, als konserviermittel dienende ammoniumverbindungen enthalten und entsprechender dosierbehälter
US5497910A (en) * 1994-05-05 1996-03-12 Allergan, Inc. Dropwise liquid dispensing system particularly suitable for liquids having low surface tension

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800253A (en) * 1952-10-07 1957-07-23 Henderson Edward Drop dispenser and container
DE1063755B (de) * 1954-10-25 1959-08-20 Sattler Atlan Werk Kg L Kunststofftropfflasche
US3189223A (en) * 1964-05-18 1965-06-15 Halkey Roberts Corp Liquid dispensing device
DE2215337A1 (de) * 1972-03-29 1973-10-11 Hans Heinlein Dichtungsanordnung fuer flascheneinsaetze
EP0114007A1 (fr) * 1983-01-13 1984-07-25 L'oreal Récipient permettant de distribuer goutte à goutte une dose de substance fluide
EP0431885A1 (fr) 1989-12-08 1991-06-12 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Embout compte-gouttes pour distribuer un produit liquide, notamment collyres
US5356052A (en) 1993-10-13 1994-10-18 Healthstar Inc. BFS metered drop bottle
EP0956904A1 (fr) 1998-05-14 1999-11-17 Lameplast S.R.L. Buse pour délivrer des gouttes de liquide
WO2002038464A1 (fr) * 2000-11-13 2002-05-16 Laboratoires Thea Distributeur de liquides goutte a goutte

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069679A1 (fr) * 2003-02-07 2004-08-19 Hoffmann Neopac Ag Distributeur goutte a goutte a insert pour optimiser la precision de dosage de liquides

Also Published As

Publication number Publication date
US20040050881A1 (en) 2004-03-18
ES2235020T3 (es) 2005-07-01
DE10112332C1 (de) 2002-08-29
EP1368245B1 (fr) 2005-01-19
JP2004529827A (ja) 2004-09-30
ATE287365T1 (de) 2005-02-15
EP1368245A1 (fr) 2003-12-10
DE50202047D1 (de) 2005-02-24

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