WO2001052767A1 - Dispositivo y método para introducir y/o recoger fluidos en el interior del utero de un animal - Google Patents
Dispositivo y método para introducir y/o recoger fluidos en el interior del utero de un animal Download PDFInfo
- Publication number
- WO2001052767A1 WO2001052767A1 PCT/ES2000/000423 ES0000423W WO0152767A1 WO 2001052767 A1 WO2001052767 A1 WO 2001052767A1 ES 0000423 W ES0000423 W ES 0000423W WO 0152767 A1 WO0152767 A1 WO 0152767A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flexible
- probe
- animal
- tube
- uterine horn
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/04—Instruments or methods for reproduction or fertilisation for embryo transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
- A61D19/027—Devices for injecting semen into animals, e.g. syringes, guns, probes
Definitions
- the invention that concerns us refers to a probe for introducing and / or collecting, non-surgically, fluids that may or may not contain cells inside the uterus of a mammal; and which aims to make it possible to cross the cervical canal (cervix) and reach the depth of the uterine horns, simply and quickly without the need for sedation or anesthesia.
- the invention is preferably applicable in pigs to allow the introduction into a station sow, a fluid with sperm, embryos or therapeutic solutions in the anterior third of a uterine horn, near the uterus-tubal junction, or to obtain embryos from the upper portions of the uterine horn.
- the invention can also be applied in small ruminants such as sheep, goats, or any other animal species.
- non-surgical systems have been developed, but these have been limited to those species, such as bovids and equidae, in which due to their body volume and anatomical configuration, their use does not present difficulties.
- species such as bovids and equidae
- non-surgical systems have had a limited diffusion due to the difficulties encountered in crossing the cervical canal and reaching deep uterine positions, since the cervical canal is affected by a series of prominences that make it difficult to introduce a probe.
- This circumstance has prevented the practical application of embryo transfer and has limited artificial insemination to the deposition of seminal samples at a deep vaginal or cervical level with a high number of sperm.
- biotechnologies such as sperm cryopreservation, sex preselection by sperm separation, embryonic micromanipulation, etc. They are limited by these circumstances.
- a tube or catheter is used at whose proximal end a widening is included to facilitate its handling, and on whose outer surface of the distal end a spiral is included that facilitates its introduction and fixation at the entrance of the cervical duct, of form that is allowed to introduce a rigid tube inside which crosses the cervical canal reaching the body of the uterus.
- a probe is inserted which, due to its configuration, does not usually progress beyond the beginning of the uterine horns.
- the invention has developed a new device and method that allows the sow in season and without the need for sedation or anesthesia, to introduce a fluid with sperm, embryos or therapeutic solutions in the anterior third of a uterine horn, near the uterus-tubal junction; or that allows to obtain embryos from the upper portions of the uterine horn.
- the device of the invention like conventional ones, comprises a tube or catheter at whose proximal end it includes a widening to facilitate its handling, and at whose outer surface of the distal end it includes a spiral, which facilitates its introduction and fixation. at the entrance of the cervical canal, so that a probe is allowed to be inserted through the tube.
- the novelty of the device of the invention is centered on the probe, which is constituted by a flexible tubular body that inside includes at least one flexible conduit, and whose exterior is covered with a layer of flexible material, plastic or any other material that allows the probe to slide without causing any damage to the mucous membranes of the female reproductive system.
- This structure allows the probe after reaching the distal end of the tube, to progress first through the cervical canal and then through the uterine horn.
- Another feature of the invention resides in the fact that at the proximal end of the probe, means for coupling a key, of at least one way, are provided to enable the introduction and / or collection of fluids.
- the probe has sufficient consistency and elasticity to allow it to progress through the cervical canal after reaching the distal end of the tube. and by the uterine horn, for which between the flexible conduit of the probe and its tubular body, it comprises a longitudinal chamber in which a plurality of flexible longitudinal ribs are included to increase its consistency while maintaining its flexibility.
- the flexible longitudinal ribs are determined by steel wires, and the longitudinal chamber that includes them is tubular.
- the distal end of the probe is formed by a piece that adapts to the internal light of the flexible tubular body and the flexible conduit; all this so that the piece includes a hole that is arranged as a continuation of the flexible conduit to determine the entry and / or exit of fluids.
- the end of this piece should be smooth and blunt to avoid damage to the mucous membranes.
- the coupling means of the key at the proximal end of the probe are determined by a piece that, on the one hand, adapts to the internal light of the flexible tubular body and the flexible conduit, and on the other hand they adapt to the key, to allow to introduce-extract fluids.
- the probe has two flexible, preferably concentric ducts, one of which, preferably the outside, and in proximity to the distal end of the probe, communicates with a small elastic outer shell, so that a Once the probe is located in the uterine horn, the small elastic outer covering fills with air and swells like a balloon, through the flexible duct, to adapt to the wall of the uterine horn and prevent the possible reflux of the liquids introduced into the uterine horn, when intrauterine fluids containing embryos are aspirated.
- the flexible conduit, which communicates with the small elastic outer covering is determined by the longitudinal chamber in which the flexible longitudinal ribs are included, among which the passage of air into the small elastic outer covering is allowed.
- the invention also relates to a method for the non-surgical introduction of fluids containing sperm, embryos or therapeutic solutions in the anterior third of a uterine horn or to collect embryos from the anterior third of the uterine horn, without the need to sedate the female and without disturbing their well-being, for which the method includes the introduction of the tube inside the vagina to the entrance of the cervical duct, at which point the tube is rotated counterclockwise, to produce its advance into of the cervical duct of the female, thanks to which there is a firm grip on its walls.
- the distal end of the flexible probe is inserted through the proximal end of the tube until it reaches the anterior end of the tube anchored inside the cervical canal, then rotate the tube slightly to the left and right, simultaneously propelling the flexible probe until it passes the first prominence of the cervical cavity. Subsequently, the flexible probe is propelled, noting how it progresses with some difficulty, through the different prominences of the cervical canal, until it reaches the body of the uterus.
- the cervical duct is saved, the resistance offered by the cervical prominences ceases and the flexible catheter is introduced smoothly, without difficulty, until reaching the upper portions of a uterine horn.
- the method comprises a phase after the introduction of the probe, in which the small elastic outer covering is inflated, adapting it to the internal lumen of the uterine horn, and then Performs embryo aspiration from the anterior portion of the uterine horn.
- the device and method of the invention does not require sedation or anesthesia of the sow. In addition, it does not cause any damage to the animal's well-being, by not using any rigid instrument that can damage and / or perforate the walls of the cervical canal, since the flexible probe has the right balance between consistency and flexibility to cross the canal itself cervical and reach the anterior third of a uterine horn, without causing apparent damage.
- the invention has the great advantage that the complete introduction of the flexible probe is achieved in a minimum time, approximately 3 or 4 minutes and allows working with reduced volumes, at the same time that it is multifunctional by allowing the introduction into the depths of the uterus of sperm, embryos and therapeutic fluids, as well as the collection of embryos from the anterior portions of the uterine horn.
- Figure 1 Shows a side elevation view of the device of the invention, in which the probe is inside the tube or catheter. Different sections have been made to show the different components that constitute.
- Figure 4.- Shows a schematic representation of the device of the invention in a working situation within the uterus of a sow.
- Figure 5. Shows a schematic representation of an embodiment of the flexible probe of the invention, used to obtain embryos from the anterior third of a uterine horn. A detail of the distal end of the probe is also shown. DESCRIPTION OF THE PREFERRED EMBODIMENT
- the invention is constituted by a device comprising a tube 1, whose outer surface of its distal end includes a spiral 3 that facilitates its introduction, and at whose proximal end it includes a widening 4 to facilitate its handling.
- a smooth tubular section 2 is provided between the ends of the tube 1.
- the tube Internally the tube is affected by a hole 5 that communicates both ends of the tube 1, and has a diameter wide enough to allow the passage of a flexible probe 6 without any difficulty.
- the ends of the tube 1 may be a single piece of rubber or plastic, or they may consist of molded plastic parts, taking into account that the distal end must be soft and flexible to avoid damage to the animal when it is introduced into the cervical canal.
- Flexible probe 6 consists of a body flexible tubular 7, either plastic or metal. The outer surface of the flexible tubular body 7 is covered with a layer 8 of plastic or any other material, which allows it to slide without causing any damage to the mucous membranes of the female reproductive system.
- a flexible conduit 12 of silicone or other similar material, all in such a way that between said flexible conduit 12 and the flexible tubular body 7 a longitudinal chamber 9 is formed, which runs from the proximal end 10 to the distal end 11, connecting in both cases with the outside.
- the proximal end 10 is formed by a device of plastic or other material 14, which allows on one of its sides the coupling with the flexible tubular body 7 and with the flexible conduit 12, and on the other hand, the coupling of a key 32 one or two way 33, 34.
- the distal end 11 of the probe is formed by a device 15 of methacrylate, plastic, metal or any other material, which allows for its end 16 its adaptation to the internal light of the flexible tubular body 7, and the flexible conduit 12, the opposite end 17 being connected to the outside through a hole that constitutes the fluid inlet and / or outlet. Said end 17 must be smooth and blunt to avoid damage to the mucous membranes of the animal.
- the device of the invention is suitably sterilized and packaged in hermetically sealed bags to avoid contamination.
- the method of the invention consists in introducing the tube 1 into the cervical duct of a sow in heat, superovulated or not. To do this, a non-toxic lubricating liquid is applied to the tube 1 in order to facilitate its passage through the vagina.
- the tube 1 is inserted by inserting its distal end (spiral zone 3) into the sow's vagina until it reaches the distal end 18 of the cervical duct 19. At that time, the tube 1 is rotated counterclockwise , so that its advance takes place inside the cervical duct 19 of the female, thanks to which there is a firm hold on the cervical neck walls, which are formed by thick rounded prominences 20.
- the tube 1 when the tube 1 from the outside, the firm support of the cervix is established, so that it does not suffer tears.
- the distal end 11 of the flexible probe 6 is inserted through the proximal end of the tube 1, until it reaches the distal end of the tube 1 inside the cervical duct 19, which is manifested due to the impossibility of progression of the flexible probe 6.
- the tube 1 rotates slightly to the left and right, simultaneously propelling the flexible probe 6 until it passes the first prominence 20 of the cervical neck 19. Subsequently, it is continued propelling the flexible probe 6 noting how it crosses, with some resistance, the different prominences 20 of the cervical duct until it reaches the body of the uterus 21.
- the resistance offered by the cervical prominences 20 and the flexible probe 6 cease it is introduced smoothly, without difficulty, until reaching the anterior portion of a uterine horn 22, for which the The uterine horn adapts as the flexible probe progresses, adopting a spiral appearance 23.
- the introduction of small volumes of diluent through the flexible conduit 12 this would facilitate the progression of the flexible probe 6 during its passage through the cervical duct 19, and its progression through the uterine horn 22.
- This same device and method can be used to obtain embryos inside a uterine horn, for which a flexible probe 24, shown in Figure 5, is provided, which is similar to that described in Figure 2, with the difference that the probe 24 has in its interior two flexible ducts 27 and 29, arranged concentrically, it being provided that in proximity to the distal end 25 of the probe 24, a device 26 consisting of a small elastic outer covering 28 is included, which it communicates through a hole 31 with the flexible conduit 27.
- the embryo culture medium is introduced to fill the portion between the tip 30 (equivalent to 15) of the flexible probe 24 and the tubal uterine junction with liquid, place where the embryos 4 to 5 days after insemination of the female. Subsequently, the same working channel 29 aims to recover the introduced liquid. This process is repeated until embryos can be obtained.
- the flexible tube 27 is determined by the chamber 9, in which the steel threads 13 are included, in which case the air circulates between said steel threads 13, thereby simplifying the structure of the probe.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Transplantation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Processing Of Solid Wastes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Fats And Perfumes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT00972916T ATE265826T1 (de) | 2000-01-20 | 2000-11-03 | Vorrichtung und verfahren zum einbringen oder entnehmen von flüssigkeiten aus dem inneren des uterus eines tieres |
EP00972916A EP1177776B1 (en) | 2000-01-20 | 2000-11-03 | Device and method for introducing and/or collecting fluids from the interior of the uterus of an animal |
AU11476/01A AU776612B2 (en) | 2000-01-20 | 2000-11-03 | A device and method for introducing and/or collecting fluids in the inside of an animal uterus |
CA002365080A CA2365080C (en) | 2000-01-20 | 2000-11-03 | Device and method for introducing and/or collecting fluids in the inside of an animal uterus |
MXPA01009487A MXPA01009487A (es) | 2000-01-20 | 2000-11-03 | Dispositivo y metodo para introducir y/o recoger fluidos en el interior del utero de un animal. |
DE60010455T DE60010455T2 (de) | 2000-01-20 | 2000-11-03 | Vorrichtung und verfahren zum einbringen oder entnehmen von flüssigkeiten aus dem inneren des uterus eines tieres |
US09/957,693 US6695767B2 (en) | 2000-01-20 | 2001-09-20 | Device, a probe and a method for introducing and/or collecting fluids in the inside of an animal uterus |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP200000114 | 2000-01-20 | ||
ES200000114A ES2156579B1 (es) | 2000-01-20 | 2000-01-20 | Dispositivo y metodo para introducir y/o recoger fluidos en el interior del utero de un animal. |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/957,693 Continuation-In-Part US6695767B2 (en) | 2000-01-20 | 2001-09-20 | Device, a probe and a method for introducing and/or collecting fluids in the inside of an animal uterus |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001052767A1 true WO2001052767A1 (es) | 2001-07-26 |
Family
ID=8491992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES2000/000423 WO2001052767A1 (es) | 2000-01-20 | 2000-11-03 | Dispositivo y método para introducir y/o recoger fluidos en el interior del utero de un animal |
Country Status (11)
Country | Link |
---|---|
US (1) | US6695767B2 (es) |
EP (1) | EP1177776B1 (es) |
AT (1) | ATE265826T1 (es) |
AU (1) | AU776612B2 (es) |
CA (1) | CA2365080C (es) |
DE (1) | DE60010455T2 (es) |
DK (1) | DK1177776T3 (es) |
ES (1) | ES2156579B1 (es) |
MX (1) | MXPA01009487A (es) |
PT (1) | PT1177776E (es) |
WO (1) | WO2001052767A1 (es) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011153603A1 (pt) * | 2010-06-09 | 2011-12-15 | Empresa Brasileira De Pesquisa Agropecuária - Embrapa - | Sonda para coleta de embriões pela via trans-cervical em caprinos e ovinos |
RU2571789C1 (ru) * | 2014-07-29 | 2015-12-20 | Государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии Российской академии сельскохозяйственных наук (ГНУ ВНИВИПФиТ Россельхозакадемии) | Комплект для получения цервикально-маточной слизи у свиноматок |
ES2600378A1 (es) * | 2016-07-12 | 2017-02-08 | Universidad De Murcia | Dispositivo de inseminación intracervical profunda en ganado porcino. |
US11925529B2 (en) | 2018-08-31 | 2024-03-12 | Inguran, Llc | Devices and methods for artificial insemination |
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US6379334B1 (en) * | 1997-02-10 | 2002-04-30 | Essex Technology, Inc. | Rotate advance catheterization system |
WO2001023027A1 (en) | 1999-09-27 | 2001-04-05 | Essex Technology, Inc. | Rotate-to-advance catheterization system |
GB0120645D0 (en) | 2001-08-24 | 2001-10-17 | Smiths Group Plc | Medico-surgical devices |
US7175590B2 (en) * | 2001-11-01 | 2007-02-13 | Continental Plastic Corp. | Apparatus for trans-cervical artificial insemination and embryo transfer |
FR2850860B1 (fr) * | 2003-02-10 | 2005-05-20 | Imv Technologies | Procede de transfert pour une paillette, conduit pour la mise en oeuvre de ce procede et instrument comportant ce conduit |
GB0307350D0 (en) | 2003-03-29 | 2003-05-07 | Smiths Group Plc | Catheters |
WO2006093976A1 (en) | 2005-02-28 | 2006-09-08 | Spirus Medical Inc. | Rotate-to-advance catheterization system |
US7780650B2 (en) | 2005-05-04 | 2010-08-24 | Spirus Medical, Inc. | Rotate-to-advance catheterization system |
US8414477B2 (en) * | 2005-05-04 | 2013-04-09 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US8235942B2 (en) | 2005-05-04 | 2012-08-07 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US8317678B2 (en) | 2005-05-04 | 2012-11-27 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US8343040B2 (en) * | 2005-05-04 | 2013-01-01 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US8574220B2 (en) | 2006-02-28 | 2013-11-05 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US8435229B2 (en) | 2006-02-28 | 2013-05-07 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
US20080269549A1 (en) * | 2007-04-27 | 2008-10-30 | The Jackson Laboratory | Method, article, and apparatus for cryopreservation of biological samples |
US8870755B2 (en) | 2007-05-18 | 2014-10-28 | Olympus Endo Technology America Inc. | Rotate-to-advance catheterization system |
DK2160129T3 (da) * | 2007-05-18 | 2020-11-30 | Spirus Medical Inc | Kateteriseringssystem med fremskydning ved rotation |
US9433484B2 (en) * | 2007-07-27 | 2016-09-06 | Brad K. Stroud | Artificial breeding techniques for bovines including semen diluents and AI apparatus |
ES2348528B1 (es) * | 2008-09-26 | 2011-09-28 | Universidad De Murcia | Dispositivo y procedimiento de introduccion u obtencion de un fluido con gametos, embriones o cualquier otro tipo de solucion del interior del oviducto de una cerda. |
DE102009047423A1 (de) | 2009-12-02 | 2011-06-09 | German Genetics International Gmbh | Kathetervorrichtung |
CN101851637B (zh) * | 2010-01-15 | 2011-12-14 | 中国农业科学院北京畜牧兽医研究所 | 一种制备同时表达多个基因的转基因动物的方法 |
CN101892256B (zh) * | 2010-01-27 | 2012-05-09 | 中国农业科学院北京畜牧兽医研究所 | 一种培育猪生长激素表达量增强的转基因动物的方法 |
EP2603167B1 (en) | 2010-08-10 | 2020-03-04 | Brad K. Stroud | Apparatus to reduce the number of sperm used in artificial insemination of cattle |
US10610343B2 (en) | 2013-07-03 | 2020-04-07 | Brad K. Stroud | Method, apparatus and kit for artificial insemination of bovine |
US11622844B2 (en) | 2010-08-10 | 2023-04-11 | Maximate, Llc | Method, apparatus and kit for artificial insemination of bovine |
DE102011076844A1 (de) | 2011-05-31 | 2012-12-06 | German Genetics International Gmbh | Endoskop zum Gametentransfer |
US9888990B2 (en) | 2012-06-06 | 2018-02-13 | Inguran, Llc | Methods for use of sex sorted semen to improve genetic management in swine |
US9433195B2 (en) | 2012-06-06 | 2016-09-06 | Inguran, Llc | Methods for increasing genetic progress in a line or breed of swine using sex-selected sperm cells |
CN109793561B (zh) * | 2019-01-17 | 2020-04-03 | 赵红岩 | 一种生殖医学用人工授精移植装置 |
ES2822399B2 (es) * | 2019-10-31 | 2022-02-16 | Univ Murcia | Dispositivo de recogida de fluido uterino in vivo |
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EP0214043A1 (fr) * | 1985-08-19 | 1987-03-11 | Etablissement public dit: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE | Instrument et procédé pour l'insémination artificielle, la transplantation d'embryons in-utéro ou le prélèvement de liquide folliculaire par voie transpéritonéale chez les animaux |
US4701164A (en) * | 1983-12-16 | 1987-10-20 | Robert Cassou | Gynecological instruments, especially for transferring embryos |
EP0478155A1 (en) * | 1990-09-28 | 1992-04-01 | Ovamed Corporation | Delivery catheter |
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EP0803237A1 (en) * | 1996-04-22 | 1997-10-29 | Enrique Horacio Turin | Intrauterine device for use in dogs and methods of insertion thereof |
US5916144A (en) * | 1995-05-09 | 1999-06-29 | The Curators Of The University Of Missouri | System for introducing a fluid into the uterus of an animal |
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WO2001049205A1 (es) * | 2000-01-03 | 2001-07-12 | Iberica De Reproduccion Asistida, S.L. | Dispositivo de inseminacion artificial en ganado porcino |
US6527703B2 (en) * | 2001-06-14 | 2003-03-04 | Minitube Of America, Inc. | Device for sow-intra-uterine insemination and embryo transfer |
-
2000
- 2000-01-20 ES ES200000114A patent/ES2156579B1/es not_active Expired - Fee Related
- 2000-11-03 WO PCT/ES2000/000423 patent/WO2001052767A1/es active IP Right Grant
- 2000-11-03 MX MXPA01009487A patent/MXPA01009487A/es active IP Right Grant
- 2000-11-03 PT PT00972916T patent/PT1177776E/pt unknown
- 2000-11-03 EP EP00972916A patent/EP1177776B1/en not_active Expired - Lifetime
- 2000-11-03 AT AT00972916T patent/ATE265826T1/de active
- 2000-11-03 AU AU11476/01A patent/AU776612B2/en not_active Expired
- 2000-11-03 DK DK00972916T patent/DK1177776T3/da active
- 2000-11-03 DE DE60010455T patent/DE60010455T2/de not_active Expired - Lifetime
- 2000-11-03 CA CA002365080A patent/CA2365080C/en not_active Expired - Lifetime
-
2001
- 2001-09-20 US US09/957,693 patent/US6695767B2/en not_active Expired - Lifetime
Patent Citations (8)
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US4173227A (en) * | 1976-07-13 | 1979-11-06 | Cassou Bertrand M E | Injecting gun for animals, in particular for the artificial insemination of cattle |
US4100923A (en) * | 1976-12-16 | 1978-07-18 | The Upjohn Company | Extra-amniotic administration device |
US4701164A (en) * | 1983-12-16 | 1987-10-20 | Robert Cassou | Gynecological instruments, especially for transferring embryos |
EP0214043A1 (fr) * | 1985-08-19 | 1987-03-11 | Etablissement public dit: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE | Instrument et procédé pour l'insémination artificielle, la transplantation d'embryons in-utéro ou le prélèvement de liquide folliculaire par voie transpéritonéale chez les animaux |
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US5249610A (en) * | 1991-08-07 | 1993-10-05 | Robert Cassou | Single-use injector nozzle for straw filling machine, in particular for artificial insemination of animals and storage of biological products |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011153603A1 (pt) * | 2010-06-09 | 2011-12-15 | Empresa Brasileira De Pesquisa Agropecuária - Embrapa - | Sonda para coleta de embriões pela via trans-cervical em caprinos e ovinos |
RU2571789C1 (ru) * | 2014-07-29 | 2015-12-20 | Государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт патологии, фармакологии и терапии Российской академии сельскохозяйственных наук (ГНУ ВНИВИПФиТ Россельхозакадемии) | Комплект для получения цервикально-маточной слизи у свиноматок |
ES2600378A1 (es) * | 2016-07-12 | 2017-02-08 | Universidad De Murcia | Dispositivo de inseminación intracervical profunda en ganado porcino. |
US11925529B2 (en) | 2018-08-31 | 2024-03-12 | Inguran, Llc | Devices and methods for artificial insemination |
Also Published As
Publication number | Publication date |
---|---|
DK1177776T3 (da) | 2004-08-02 |
AU776612B2 (en) | 2004-09-16 |
DE60010455D1 (de) | 2004-06-09 |
AU1147601A (en) | 2001-07-31 |
US20020072650A1 (en) | 2002-06-13 |
EP1177776B1 (en) | 2004-05-06 |
ES2156579B1 (es) | 2002-01-16 |
PT1177776E (pt) | 2004-08-31 |
ATE265826T1 (de) | 2004-05-15 |
US6695767B2 (en) | 2004-02-24 |
MXPA01009487A (es) | 2003-08-19 |
CA2365080C (en) | 2006-07-04 |
EP1177776A1 (en) | 2002-02-06 |
CA2365080A1 (en) | 2001-07-26 |
ES2156579A1 (es) | 2001-06-16 |
DE60010455T2 (de) | 2005-05-12 |
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