WO2000078933A3 - Nouvelles calpaines et leur utilisation - Google Patents

Nouvelles calpaines et leur utilisation Download PDF

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Publication number
WO2000078933A3
WO2000078933A3 PCT/EP2000/005261 EP0005261W WO0078933A3 WO 2000078933 A3 WO2000078933 A3 WO 2000078933A3 EP 0005261 W EP0005261 W EP 0005261W WO 0078933 A3 WO0078933 A3 WO 0078933A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel
calpains
capn11
synthesis
relates
Prior art date
Application number
PCT/EP2000/005261
Other languages
German (de)
English (en)
Other versions
WO2000078933A2 (fr
Inventor
Neil T Dear
Thomas Boehm
Achim Moeller
Original Assignee
Basf Ag
Neil T Dear
Thomas Boehm
Achim Moeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to SK1826-2001A priority Critical patent/SK18262001A3/sk
Application filed by Basf Ag, Neil T Dear, Thomas Boehm, Achim Moeller filed Critical Basf Ag
Priority to EP00945716A priority patent/EP1185673A2/fr
Priority to KR1020017016244A priority patent/KR20020011140A/ko
Priority to BR0011721-8A priority patent/BR0011721A/pt
Priority to CA002375477A priority patent/CA2375477A1/fr
Priority to IL14694000A priority patent/IL146940A0/xx
Priority to JP2001505676A priority patent/JP2003503023A/ja
Priority to MXPA01012937A priority patent/MXPA01012937A/es
Priority to AU59706/00A priority patent/AU5970600A/en
Publication of WO2000078933A2 publication Critical patent/WO2000078933A2/fr
Publication of WO2000078933A3 publication Critical patent/WO2000078933A3/fr
Priority to NO20015922A priority patent/NO20015922L/no
Priority to BG106186A priority patent/BG106186A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne de nouvelles calpaïnes et leur utilisation.
PCT/EP2000/005261 1999-06-18 2000-06-07 Nouvelles calpaines et leur utilisation WO2000078933A2 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL14694000A IL146940A0 (en) 1999-06-18 2000-06-07 Novel calpains and their use
EP00945716A EP1185673A2 (fr) 1999-06-18 2000-06-07 Nouvelles calpaines et leur utilisation
KR1020017016244A KR20020011140A (ko) 1999-06-18 2000-06-07 신규 칼파인 및 그의 용도
BR0011721-8A BR0011721A (pt) 1999-06-18 2000-06-07 Polipeptìdeo, sequência de polinucleotìdeos, uso de um polipeptìdeo, processo para identificar compostos que inibem a atividade enzimática de um polipeptìdeo, e, uso de compostos
CA002375477A CA2375477A1 (fr) 1999-06-18 2000-06-07 Nouvelles calpaines et leur utilisation
SK1826-2001A SK18262001A3 (sk) 1999-06-18 2000-06-07 Kalpaíny a ich použitie
JP2001505676A JP2003503023A (ja) 1999-06-18 2000-06-07 新規カルパインおよびその使用
MXPA01012937A MXPA01012937A (es) 1999-06-18 2000-06-07 Calpainas novedosas y su uso.
AU59706/00A AU5970600A (en) 1999-06-18 2000-06-07 Novel calpains and their use
NO20015922A NO20015922L (no) 1999-06-18 2001-12-04 Nye calpainer og anvendelse derav
BG106186A BG106186A (bg) 1999-06-18 2001-12-06 Нови калпаини и използването им

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19928021.5 1999-06-18
DE19928021A DE19928021A1 (de) 1999-06-18 1999-06-18 Neue Calpaine und deren Verwendung

Publications (2)

Publication Number Publication Date
WO2000078933A2 WO2000078933A2 (fr) 2000-12-28
WO2000078933A3 true WO2000078933A3 (fr) 2001-07-26

Family

ID=7911777

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005261 WO2000078933A2 (fr) 1999-06-18 2000-06-07 Nouvelles calpaines et leur utilisation

Country Status (18)

Country Link
EP (1) EP1185673A2 (fr)
JP (1) JP2003503023A (fr)
KR (1) KR20020011140A (fr)
CN (1) CN1373808A (fr)
AR (1) AR024573A1 (fr)
AU (1) AU5970600A (fr)
BG (1) BG106186A (fr)
BR (1) BR0011721A (fr)
CA (1) CA2375477A1 (fr)
DE (1) DE19928021A1 (fr)
HU (1) HUP0201800A2 (fr)
IL (1) IL146940A0 (fr)
MX (1) MXPA01012937A (fr)
NO (1) NO20015922L (fr)
PL (1) PL353004A1 (fr)
SK (1) SK18262001A3 (fr)
TR (1) TR200103662T2 (fr)
WO (1) WO2000078933A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7101700A (en) 1999-09-02 2001-03-26 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
EP2563446A1 (fr) 2010-04-30 2013-03-06 Abbott Cardiovascular Systems Inc. Cathéter à ballonnet amélioré se gonflant et se dégonflant rapidement

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
WO2000058473A2 (fr) * 1999-03-31 2000-10-05 Curagen Corporation Acides nucleiques comprenant des phases de lecture ouverte codant des polypeptides; «orfx»

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEAR T NEIL ET AL: "CAPN11: A calpain with high mRNA levels in testis and located on chromosome 6.", GENOMICS, vol. 59, no. 2, 15 July 1999 (1999-07-15), pages 243 - 247, XP002159274, ISSN: 0888-7543 *
ZHANG WENLI ET AL: "The major calpain isozymes are long-lived proteins. Design of an antisense strategy for calpain depletion in cultured cells.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 31, 1996, pages 18825 - 18830, XP002159273, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
NO20015922D0 (no) 2001-12-04
HUP0201800A2 (en) 2002-09-28
IL146940A0 (en) 2002-08-14
SK18262001A3 (sk) 2002-09-10
AR024573A1 (es) 2002-10-16
BR0011721A (pt) 2002-03-05
CN1373808A (zh) 2002-10-09
NO20015922L (no) 2002-02-12
AU5970600A (en) 2001-01-09
EP1185673A2 (fr) 2002-03-13
PL353004A1 (en) 2003-09-22
CA2375477A1 (fr) 2000-12-28
WO2000078933A2 (fr) 2000-12-28
MXPA01012937A (es) 2002-07-30
DE19928021A1 (de) 2000-12-21
JP2003503023A (ja) 2003-01-28
KR20020011140A (ko) 2002-02-07
BG106186A (bg) 2002-12-29
TR200103662T2 (tr) 2002-05-21

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