WO2000077234A3 - Procedimiento de produccion de licopeno - Google Patents

Procedimiento de produccion de licopeno Download PDF

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Publication number
WO2000077234A3
WO2000077234A3 PCT/ES2000/000202 ES0000202W WO0077234A3 WO 2000077234 A3 WO2000077234 A3 WO 2000077234A3 ES 0000202 W ES0000202 W ES 0000202W WO 0077234 A3 WO0077234 A3 WO 0077234A3
Authority
WO
WIPO (PCT)
Prior art keywords
lycopen
fermentation
trisporic
production method
acids
Prior art date
Application number
PCT/ES2000/000202
Other languages
English (en)
French (fr)
Other versions
WO2000077234A2 (es
Inventor
Ana Teresa Marcos
De Castro Antonio Estrella
Bina Mehta
Garcia Bruno Diez
Perez Javier Costa
Otero Carmelita Rodriguez
Cezon Enrique Peiro
Olmedo Enrique Cerda
De La Vieja Alfonso J Collados
Maldonado Francisco Salto
Morales Manuel Esteban
Ermanno Bernasconi
Original Assignee
Vitatene Sa
Ana Teresa Marcos
De Castro Antonio Estrella
Bina Mehta
Garcia Bruno Diez
Perez Javier Costa
Otero Carmelita Rodriguez
Cezon Enrique Peiro
Olmedo Enrique Cerda
De La Vieja Alfonso J Collados
Maldonado Francisco Salto
Morales Manuel Esteban
Ermanno Bernasconi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitatene Sa, Ana Teresa Marcos, De Castro Antonio Estrella, Bina Mehta, Garcia Bruno Diez, Perez Javier Costa, Otero Carmelita Rodriguez, Cezon Enrique Peiro, Olmedo Enrique Cerda, De La Vieja Alfonso J Collados, Maldonado Francisco Salto, Morales Manuel Esteban, Ermanno Bernasconi filed Critical Vitatene Sa
Priority to JP2001503676A priority Critical patent/JP3904924B2/ja
Priority to DE60023693T priority patent/DE60023693T2/de
Priority to EP00935226A priority patent/EP1184464B1/en
Priority to AT00935226T priority patent/ATE308622T1/de
Priority to AU50792/00A priority patent/AU5079200A/en
Publication of WO2000077234A2 publication Critical patent/WO2000077234A2/es
Publication of WO2000077234A3 publication Critical patent/WO2000077234A3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Glass Compositions (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procedimiento para la producción de licopeno. La presente invención se refiere a un nuevo procedimiento para la obtención de carotenoides, especialmente como Blakeslea. Se describe un método de fermentación que permite obtener un incremento en la producción de licopeno, basado en la adición de ácidos trispóricos. El proceso se lleva a cabo a partir de estirpes silvestres o mutantes de las mismas, en cultivo simple o mixto. La adición de ácidos trispóricos puede hacerse al inicio de la fermentación o durante la misma y su origen puede ser una preparación parcialmente purificada o una fuente no purificada de los mismos.
PCT/ES2000/000202 1999-06-09 2000-06-06 Procedimiento de produccion de licopeno WO2000077234A2 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2001503676A JP3904924B2 (ja) 1999-06-09 2000-06-06 リコペンを製造する方法
DE60023693T DE60023693T2 (de) 1999-06-09 2000-06-06 Herstellungsverfahren für lycopen
EP00935226A EP1184464B1 (en) 1999-06-09 2000-06-06 Lycopen production method
AT00935226T ATE308622T1 (de) 1999-06-09 2000-06-06 Herstellungsverfahren für lycopen
AU50792/00A AU5079200A (en) 1999-06-09 2000-06-06 Lycopen production method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901271A ES2156735B1 (es) 1999-06-09 1999-06-09 Procedimiento de produccion de licopeno.
ESP9901271 1999-06-09

Publications (2)

Publication Number Publication Date
WO2000077234A2 WO2000077234A2 (es) 2000-12-21
WO2000077234A3 true WO2000077234A3 (es) 2001-02-08

Family

ID=8308761

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2000/000202 WO2000077234A2 (es) 1999-06-09 2000-06-06 Procedimiento de produccion de licopeno

Country Status (8)

Country Link
EP (1) EP1184464B1 (es)
JP (1) JP3904924B2 (es)
CN (1) CN1252276C (es)
AT (1) ATE308622T1 (es)
AU (1) AU5079200A (es)
DE (1) DE60023693T2 (es)
ES (2) ES2156735B1 (es)
WO (1) WO2000077234A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002316966B2 (en) 2001-06-06 2007-05-17 Dsm Ip Assets B.V. Improved isoprenoid production
RU2211862C2 (ru) * 2001-10-29 2003-09-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (-) ШТАММ ГЕТЕРОТАЛЛИЧНОГО ФИКОМИЦЕТА Blakeslea trispora, ПРОДУЦИРУЮЩИЙ ЛИКОПИН В ПАРЕ С РАЗНЫМИ (+)ШТАММАМИ Blakeslea trispora, И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА ЛИКОПИНА
ES2195758B1 (es) * 2001-12-31 2005-03-01 Antibioticos, S.A.U. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
EP1592784A1 (de) * 2003-01-09 2005-11-09 Basf Aktiengesellschaft Verfahren zur gentechnischen veränderung von organismen der gattung blakeslea, entsprechende organismen und deren verwendung
JP2006515516A (ja) * 2003-01-09 2006-06-01 ビーエーエスエフ　アクチェンゲゼルシャフト 遺伝子改変されたＢｌａｋｅｓｌｅａ属の生物を使用する、カロチノイドまたはそれらの前駆体を製造するための方法、上記方法によって製造されたカロチノイドまたはそれらの前駆体、ならびにそれらの使用
CN100335642C (zh) * 2005-03-16 2007-09-05 佛山市英迈瑞生物技术服务有限公司 基因重组毕赤酵母生产番茄红素的方法
CN102140052B (zh) * 2010-12-30 2013-12-18 南京工业大学 一种连续提取番茄红素的方法
CN102787158B (zh) 2011-05-20 2015-01-21 浙江医药股份有限公司新昌制药厂 一种发酵法生产天然β-胡萝卜素的方法和应用
CN102251008B (zh) * 2011-06-09 2013-05-29 北京化工大学 一种提高由三孢布拉氏霉菌生产番茄红素产量的方法
CN109280685B (zh) * 2017-07-21 2021-11-23 浙江医药股份有限公司新昌制药厂 通过增加天然类胡萝卜素发酵过程中溶氧生产天然类胡萝卜素的方法
CN108004272B (zh) * 2017-12-28 2021-09-21 嘉必优生物技术（武汉）股份有限公司 一种利用三孢布拉氏霉菌制备番茄红素的方法及番茄红素制品
GB202211084D0 (en) 2022-07-29 2022-09-14 Givaudan Sa Composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1034944A (en) * 1963-08-02 1966-07-06 Farmaceutici Italia Production of ª‰-carotene
GB1114043A (en) * 1964-09-23 1968-05-15 Upjohn Co Improvements in or relating to acid compounds and the manufacture thereof by a microbiological method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1034944A (en) * 1963-08-02 1966-07-06 Farmaceutici Italia Production of ª‰-carotene
GB1114043A (en) * 1964-09-23 1968-05-15 Upjohn Co Improvements in or relating to acid compounds and the manufacture thereof by a microbiological method

Also Published As

Publication number Publication date
EP1184464B1 (en) 2005-11-02
AU5079200A (en) 2001-01-02
EP1184464A2 (en) 2002-03-06
ES2156735A1 (es) 2001-07-01
CN1353765A (zh) 2002-06-12
ES2252009T3 (es) 2006-05-16
JP3904924B2 (ja) 2007-04-11
ES2156735B1 (es) 2002-02-16
WO2000077234A2 (es) 2000-12-21
DE60023693T2 (de) 2006-07-20
CN1252276C (zh) 2006-04-19
JP2003502052A (ja) 2003-01-21
ATE308622T1 (de) 2005-11-15
DE60023693D1 (de) 2005-12-08

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