WO2000072052A1 - Surface treatment of medical devices with reactive hydrophilic polymers - Google Patents

Surface treatment of medical devices with reactive hydrophilic polymers Download PDF

Info

Publication number
WO2000072052A1
WO2000072052A1 PCT/US2000/013229 US0013229W WO0072052A1 WO 2000072052 A1 WO2000072052 A1 WO 2000072052A1 US 0013229 W US0013229 W US 0013229W WO 0072052 A1 WO0072052 A1 WO 0072052A1
Authority
WO
WIPO (PCT)
Prior art keywords
reactive
hydrophilic
medical device
polymer
functionalities
Prior art date
Application number
PCT/US2000/013229
Other languages
English (en)
French (fr)
Inventor
Paul L. Valint, Jr.
Joseph A. Mcgee
Joseph C. Salamone
Richard M. Ozark
Original Assignee
Bausch & Lomb Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb Incorporated filed Critical Bausch & Lomb Incorporated
Priority to AU47138/00A priority Critical patent/AU762372B2/en
Priority to EP20000928986 priority patent/EP1179190B1/en
Priority to KR1020017014799A priority patent/KR20020013890A/ko
Priority to BR0011610A priority patent/BR0011610A/pt
Priority to JP2000620386A priority patent/JP4544753B2/ja
Priority to DE2000627289 priority patent/DE60027289T2/de
Priority to MXPA01011853A priority patent/MXPA01011853A/es
Priority to CA 2373541 priority patent/CA2373541A1/en
Publication of WO2000072052A1 publication Critical patent/WO2000072052A1/en
Priority to HK02105310.0A priority patent/HK1045375B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/0427Coating with only one layer of a composition containing a polymer binder
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04Coating
    • C08J7/056Forming hydrophilic coatings
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2383/00Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon only; Derivatives of such polymers
    • C08J2383/04Polysiloxanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31652Of asbestos
    • Y10T428/31663As siloxane, silicone or silane
PCT/US2000/013229 1999-05-20 2000-05-12 Surface treatment of medical devices with reactive hydrophilic polymers WO2000072052A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
AU47138/00A AU762372B2 (en) 1999-05-20 2000-05-12 Surface treatment of medical devices with reactive hydrophilic polymers
EP20000928986 EP1179190B1 (en) 1999-05-20 2000-05-12 Surface treatment of medical devices with reactive hydrophilic polymers
KR1020017014799A KR20020013890A (ko) 1999-05-20 2000-05-12 반응성 친수성 중합체를 사용한 의료 장치의 표면 처리 방법
BR0011610A BR0011610A (pt) 1999-05-20 2000-05-12 Tratamento de superfìcie de dispositivos médicos com polìmeros hidrófilos reativos
JP2000620386A JP4544753B2 (ja) 1999-05-20 2000-05-12 反応性親水性ポリマーによる医療デバイスの表面処理
DE2000627289 DE60027289T2 (de) 1999-05-20 2000-05-12 Oberflächenbehandlung von medizinischen artikeln mit reaktiven hydrophilen polymeren
MXPA01011853A MXPA01011853A (es) 1999-05-20 2000-05-12 Tratamiento superficial de dispositivos medicos de silicona con polimeros hidrofilos reactivos.
CA 2373541 CA2373541A1 (en) 1999-05-20 2000-05-12 Surface treatment of medical devices with reactive hydrophilic polymers
HK02105310.0A HK1045375B (zh) 1999-05-20 2002-07-17 利用活性親水聚合物對醫療設施進行的表面處理方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/315,620 US6440571B1 (en) 1999-05-20 1999-05-20 Surface treatment of silicone medical devices with reactive hydrophilic polymers
US09/315,620 1999-05-20

Publications (1)

Publication Number Publication Date
WO2000072052A1 true WO2000072052A1 (en) 2000-11-30

Family

ID=23225286

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/013229 WO2000072052A1 (en) 1999-05-20 2000-05-12 Surface treatment of medical devices with reactive hydrophilic polymers

Country Status (15)

Country Link
US (2) US6440571B1 (US06440571-20020827-C00012.png)
EP (1) EP1179190B1 (US06440571-20020827-C00012.png)
JP (1) JP4544753B2 (US06440571-20020827-C00012.png)
KR (1) KR20020013890A (US06440571-20020827-C00012.png)
CN (1) CN1156713C (US06440571-20020827-C00012.png)
AU (1) AU762372B2 (US06440571-20020827-C00012.png)
BR (1) BR0011610A (US06440571-20020827-C00012.png)
CA (1) CA2373541A1 (US06440571-20020827-C00012.png)
DE (1) DE60027289T2 (US06440571-20020827-C00012.png)
ES (1) ES2264665T3 (US06440571-20020827-C00012.png)
HK (1) HK1045375B (US06440571-20020827-C00012.png)
MX (1) MXPA01011853A (US06440571-20020827-C00012.png)
TW (1) TW589465B (US06440571-20020827-C00012.png)
WO (1) WO2000072052A1 (US06440571-20020827-C00012.png)
ZA (1) ZA200109528B (US06440571-20020827-C00012.png)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001074932A1 (en) * 2000-04-03 2001-10-11 Bausch & Lomb Incorporated Surface treatment of silicone medical devices
WO2002024793A1 (en) * 2000-09-19 2002-03-28 Bausch & Lomb Incorporated Method for applying polymeric lens coating
WO2002068008A1 (en) * 2001-02-28 2002-09-06 Novartis Pharma Gmbh Coated biomedical devices
EP1426809A1 (en) * 2001-08-17 2004-06-09 Johnson & Johnson Vision Care, Inc. Method for producing polymer for ophthalmic lens and ophthalmic lens
JP2004536633A (ja) * 2001-05-21 2004-12-09 ノバルティス アクチエンゲゼルシャフト 絡み合った親水性ポリマーを有するボトル−ブラシ型コーティング
JP2006513282A (ja) * 2002-12-17 2006-04-20 ボシュ・アンド・ロム・インコーポレイテッド 医療用デバイスの表面処理
WO2007047716A2 (en) * 2005-10-19 2007-04-26 Bausch & Lomb Incorporated Surface-modified medical devices and method of making
WO2007064594A2 (en) * 2005-11-29 2007-06-07 Bausch & Lomb Incorporated New coatings on ophthalmic lenses
US7270678B2 (en) 2002-06-28 2007-09-18 Bausch & Lomb Incorporated Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
WO2008005752A2 (en) * 2006-06-30 2008-01-10 Bausch & Lomb Incorporated Modification of surfaces of polymeric articles by michael addition reaction
US8944592B2 (en) 2010-07-30 2015-02-03 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
WO2016032926A1 (en) * 2014-08-26 2016-03-03 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US10338408B2 (en) 2012-12-17 2019-07-02 Novartis Ag Method for making improved UV-absorbing ophthalmic lenses
US10449740B2 (en) 2015-12-15 2019-10-22 Novartis Ag Method for applying stable coating on silicone hydrogel contact lenses
US10830923B2 (en) 2017-12-13 2020-11-10 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6822016B2 (en) 2001-09-10 2004-11-23 Johnson & Johnson Vision Care, Inc. Biomedical devices containing internal wetting agents
US7052131B2 (en) * 2001-09-10 2006-05-30 J&J Vision Care, Inc. Biomedical devices containing internal wetting agents
ATE246222T1 (de) * 1999-05-12 2003-08-15 Menicon Co Ltd Material für okularlinse und verfahren zu deren herstellung
US6428839B1 (en) * 2000-06-02 2002-08-06 Bausch & Lomb Incorporated Surface treatment of medical device
US6765069B2 (en) * 2001-09-28 2004-07-20 Biosurface Engineering Technologies, Inc. Plasma cross-linked hydrophilic coating
US20060100408A1 (en) * 2002-03-11 2006-05-11 Powell P M Method for forming contact lenses comprising therapeutic agents
US7083646B2 (en) * 2002-06-28 2006-08-01 Bausch & Lomb Incorporated Surface modification of functional group-containing intraocular lenses
US20070138692A1 (en) * 2002-09-06 2007-06-21 Ford James D Process for forming clear, wettable silicone hydrogel articles
US20060073185A1 (en) * 2002-12-13 2006-04-06 Bausch & Lomb Incorporated Method and composition for contact lenses
US20040120982A1 (en) * 2002-12-19 2004-06-24 Zanini Diana Biomedical devices with coatings attached via latent reactive components
AU2003297323A1 (en) * 2002-12-23 2004-07-22 Bausch And Lomb Incorporated Surface treatment utilizing microwave radiation
US7247387B1 (en) 2003-07-24 2007-07-24 Sepax Technologies Inc. Material and process for controlled thin polymeric coatings on plastic surface
US7084188B2 (en) * 2003-12-05 2006-08-01 Bausch & Lomb Incorporated Surface modification of contact lenses
US9322958B2 (en) 2004-08-27 2016-04-26 Coopervision International Holding Company, Lp Silicone hydrogel contact lenses
CN102323629B (zh) * 2004-08-27 2015-08-19 库柏维景国际控股公司 硅水凝胶隐形眼镜
US20070116741A1 (en) * 2005-11-21 2007-05-24 Bausch & Lomb Incorporated Contact lenses with mucin affinity
US7988988B2 (en) * 2005-11-21 2011-08-02 Bausch & Lomb Incorporated Contact lenses with mucin affinity
US20070264509A1 (en) * 2006-05-11 2007-11-15 Yu-Chin Lai Copolymer and Medical Device with the Copolymer
US20080143955A1 (en) * 2006-12-15 2008-06-19 Bausch & Lomb Incorporated Silicone Contact Lenses with Silicate Coating
US7625598B2 (en) * 2006-12-15 2009-12-01 Bausch & Lomb Incorporated Silicone contact lenses with wrinkled surface
US20080142038A1 (en) * 2006-12-15 2008-06-19 Bausch & Lomb Incorporated Surface treatment of medical devices
US20080151181A1 (en) * 2006-12-20 2008-06-26 Bausch & Lomb Incorporated Coatings and Solutions for Contact Lenses
US7832856B2 (en) * 2006-12-20 2010-11-16 Bausch & Lomb Incorporated Coatings and solutions for contact lenses
US20080206481A1 (en) * 2007-02-26 2008-08-28 Bausch & Lomb Incorporated Silicone contact lenses with wrinkled surface
US8119753B2 (en) * 2007-10-23 2012-02-21 Bausch & Lomb Incorporated Silicone hydrogels with amino surface groups
US20090111942A1 (en) * 2007-10-25 2009-04-30 Bausch & Lomb Incorporated Method for Making Surface Modified Biomedical Devices
WO2009079224A2 (en) * 2007-12-14 2009-06-25 Bausch & Lomb Incorporated Surface modified biomedical devices
EP2220134A2 (en) * 2007-12-14 2010-08-25 Bausch & Lomb Incorporated Biomedical devices
WO2009079223A1 (en) 2007-12-14 2009-06-25 Bausch & Lomb Incorporated Surface modified biomedical devices
US20090171049A1 (en) * 2007-12-27 2009-07-02 Linhardt Jeffrey G Segmented reactive block copolymers
US20100168851A1 (en) * 2008-12-30 2010-07-01 David Paul Vanderbilt Surface Modified Biomedical Devices
US8534031B2 (en) * 2008-12-30 2013-09-17 Bausch & Lomb Incorporated Packaging solutions
US8163358B2 (en) * 2009-02-18 2012-04-24 Synergeyes, Inc. Surface modification of contact lenses
JP5273675B2 (ja) * 2009-06-09 2013-08-28 株式会社メニコン 眼用レンズ用ケア用品及び樹脂基材の親水化方法
US8133960B2 (en) * 2009-06-16 2012-03-13 Bausch & Lomb Incorporated Biomedical devices
US20100315588A1 (en) * 2009-06-16 2010-12-16 Bausch & Lomb Incorporated Biomedical devices
US8083348B2 (en) * 2009-06-16 2011-12-27 Bausch & Lomb Incorporated Biomedical devices
US8043369B2 (en) 2009-06-16 2011-10-25 Bausch & Lomb Incorporated Biomedical devices
WO2011005326A1 (en) 2009-07-09 2011-01-13 Massachusetts Institute Of Technology Methods and compositions for increased safety of stem cell-derived populations
CN102576158B (zh) * 2009-10-01 2014-07-16 库柏维景国际控股公司 硅酮水凝胶隐形眼镜和制造硅酮水凝胶隐形眼镜的方法
CN102597856B (zh) 2009-11-04 2014-07-23 诺华股份有限公司 具有接枝亲水涂层的硅酮水凝胶透镜
TWI483996B (zh) * 2009-12-08 2015-05-11 Novartis Ag 具有共價貼合塗層之聚矽氧水凝膠鏡片
US9522980B2 (en) 2010-05-06 2016-12-20 Johnson & Johnson Vision Care, Inc. Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
AU2016201366B2 (en) * 2010-07-30 2017-05-25 Alcon Inc. Silicone hydrogel lenses with water-rich surfaces
JP5842297B2 (ja) 2011-02-28 2016-01-13 クーパーヴィジョン インターナショナル ホウルディング カンパニー リミテッド パートナーシップ 許容レベルのエネルギー損失を有するシリコーンヒドロゲルコンタクトレンズ
KR101743802B1 (ko) 2011-02-28 2017-06-05 쿠퍼비젼 인터내셔날 홀딩 캄파니, 엘피 실리콘 히드로겔 콘택트 렌즈 및 관련 조성물 및 방법
MX354797B (es) 2011-02-28 2018-03-21 Coopervision Int Holding Co Lp Lentes de contacto de hidrogel de silicona dimensionalmente estables.
ES2449709T3 (es) 2011-02-28 2014-03-20 Coopervision International Holding Company, Lp Lentes de contacto de hidrogel de silicona
TWI497151B (zh) 2011-02-28 2015-08-21 Coopervision Int Holding Co Lp 含膦水凝膠隱形眼鏡
CN103890044B (zh) 2011-02-28 2015-11-25 库柏维景国际控股公司 硅酮水凝胶隐形眼镜
ES2441385T3 (es) 2011-02-28 2014-02-04 Coopervision International Holding Company, Lp Lentes de contacto de hidrogel de silicona humectables
US9170349B2 (en) 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
US9005700B2 (en) 2011-10-12 2015-04-14 Novartis Ag Method for making UV-absorbing ophthalmic lenses
JP6072060B2 (ja) * 2011-11-15 2017-02-01 ノバルティス アーゲー 架橋親水性コーティングされているシリコーンヒドロゲルレンズ
EP2788797B1 (en) * 2011-12-08 2023-06-07 Alcon Inc. Contact lenses with enzymatically degradable coatings thereon
US9140825B2 (en) * 2011-12-23 2015-09-22 Johnson & Johnson Vision Care, Inc. Ionic silicone hydrogels
US9447378B2 (en) 2012-04-27 2016-09-20 Massachusetts Institute Of Technology Method for differentiating human embryonic stem cells into β-cells for the treatment of type I diabetes
US8798332B2 (en) 2012-05-15 2014-08-05 Google Inc. Contact lenses
US10073192B2 (en) 2012-05-25 2018-09-11 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
US9244196B2 (en) 2012-05-25 2016-01-26 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
CA2870333C (en) 2012-06-14 2016-10-04 Novartis Ag Azetidinium-containing copolymers and uses thereof
US8857981B2 (en) 2012-07-26 2014-10-14 Google Inc. Facilitation of contact lenses with capacitive sensors
US9523865B2 (en) 2012-07-26 2016-12-20 Verily Life Sciences Llc Contact lenses with hybrid power sources
US9298020B1 (en) 2012-07-26 2016-03-29 Verily Life Sciences Llc Input system
US9158133B1 (en) 2012-07-26 2015-10-13 Google Inc. Contact lens employing optical signals for power and/or communication
US8919953B1 (en) 2012-08-02 2014-12-30 Google Inc. Actuatable contact lenses
US9696564B1 (en) 2012-08-21 2017-07-04 Verily Life Sciences Llc Contact lens with metal portion and polymer layer having indentations
US9111473B1 (en) 2012-08-24 2015-08-18 Google Inc. Input system
US9395468B2 (en) * 2012-08-27 2016-07-19 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
US8820934B1 (en) 2012-09-05 2014-09-02 Google Inc. Passive surface acoustic wave communication
US20140192315A1 (en) 2012-09-07 2014-07-10 Google Inc. In-situ tear sample collection and testing using a contact lens
US9398868B1 (en) 2012-09-11 2016-07-26 Verily Life Sciences Llc Cancellation of a baseline current signal via current subtraction within a linear relaxation oscillator-based current-to-frequency converter circuit
US10010270B2 (en) 2012-09-17 2018-07-03 Verily Life Sciences Llc Sensing system
US9326710B1 (en) 2012-09-20 2016-05-03 Verily Life Sciences Llc Contact lenses having sensors with adjustable sensitivity
US8960898B1 (en) 2012-09-24 2015-02-24 Google Inc. Contact lens that restricts incoming light to the eye
US8870370B1 (en) 2012-09-24 2014-10-28 Google Inc. Contact lens that facilitates antenna communication via sensor impedance modulation
US8979271B2 (en) 2012-09-25 2015-03-17 Google Inc. Facilitation of temperature compensation for contact lens sensors and temperature sensing
US8989834B2 (en) 2012-09-25 2015-03-24 Google Inc. Wearable device
US20140088372A1 (en) 2012-09-25 2014-03-27 Google Inc. Information processing method
US8960899B2 (en) 2012-09-26 2015-02-24 Google Inc. Assembling thin silicon chips on a contact lens
US8985763B1 (en) 2012-09-26 2015-03-24 Google Inc. Contact lens having an uneven embedded substrate and method of manufacture
US9884180B1 (en) 2012-09-26 2018-02-06 Verily Life Sciences Llc Power transducer for a retinal implant using a contact lens
US8821811B2 (en) 2012-09-26 2014-09-02 Google Inc. In-vitro contact lens testing
US9063351B1 (en) 2012-09-28 2015-06-23 Google Inc. Input detection system
US8965478B2 (en) 2012-10-12 2015-02-24 Google Inc. Microelectrodes in an ophthalmic electrochemical sensor
US9176332B1 (en) 2012-10-24 2015-11-03 Google Inc. Contact lens and method of manufacture to improve sensor sensitivity
US9757056B1 (en) 2012-10-26 2017-09-12 Verily Life Sciences Llc Over-molding of sensor apparatus in eye-mountable device
CN104837612B (zh) 2012-12-11 2017-08-25 诺华股份有限公司 将涂层施加于硅酮水凝胶透镜上的方法
US8874182B2 (en) 2013-01-15 2014-10-28 Google Inc. Encapsulated electronics
US9289954B2 (en) 2013-01-17 2016-03-22 Verily Life Sciences Llc Method of ring-shaped structure placement in an eye-mountable device
US20140209481A1 (en) 2013-01-25 2014-07-31 Google Inc. Standby Biasing Of Electrochemical Sensor To Reduce Sensor Stabilization Time During Measurement
US9636016B1 (en) 2013-01-25 2017-05-02 Verily Life Sciences Llc Eye-mountable devices and methods for accurately placing a flexible ring containing electronics in eye-mountable devices
US9161712B2 (en) 2013-03-26 2015-10-20 Google Inc. Systems and methods for encapsulating electronics in a mountable device
US9113829B2 (en) 2013-03-27 2015-08-25 Google Inc. Systems and methods for encapsulating electronics in a mountable device
ES2881278T3 (es) * 2013-04-26 2021-11-29 Biointeractions Ltd Recubrimientos bioactivos
USRE49528E1 (en) * 2013-04-26 2023-05-16 Biointeractions Ltd. Bioactive coatings
US9816070B2 (en) * 2013-06-14 2017-11-14 Massachusetts Institute Of Technology Articles and methods for stem cell differentiation
US20140371560A1 (en) 2013-06-14 2014-12-18 Google Inc. Body-Mountable Devices and Methods for Embedding a Structure in a Body-Mountable Device
US9084561B2 (en) 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
US9948895B1 (en) 2013-06-18 2018-04-17 Verily Life Sciences Llc Fully integrated pinhole camera for eye-mountable imaging system
US9685689B1 (en) 2013-06-27 2017-06-20 Verily Life Sciences Llc Fabrication methods for bio-compatible devices
US9307901B1 (en) 2013-06-28 2016-04-12 Verily Life Sciences Llc Methods for leaving a channel in a polymer layer using a cross-linked polymer plug
US9492118B1 (en) 2013-06-28 2016-11-15 Life Sciences Llc Pre-treatment process for electrochemical amperometric sensor
US9814387B2 (en) 2013-06-28 2017-11-14 Verily Life Sciences, LLC Device identification
US9028772B2 (en) 2013-06-28 2015-05-12 Google Inc. Methods for forming a channel through a polymer layer using one or more photoresist layers
CN103405807B (zh) * 2013-07-05 2014-10-08 温州医科大学 一种表面梳状聚合物亲水改性的人工晶状体及其制备方法
AU2014348502B2 (en) 2013-11-15 2019-08-15 Tangible Science, Inc. Contact lens with a hydrophilic layer
CN103705965B (zh) * 2013-12-10 2015-07-08 浙江大学 一种超薄抗菌水凝胶薄膜的制备方法
US9572522B2 (en) 2013-12-20 2017-02-21 Verily Life Sciences Llc Tear fluid conductivity sensor
US9654674B1 (en) 2013-12-20 2017-05-16 Verily Life Sciences Llc Image sensor with a plurality of light channels
US9366570B1 (en) 2014-03-10 2016-06-14 Verily Life Sciences Llc Photodiode operable in photoconductive mode and photovoltaic mode
US9184698B1 (en) 2014-03-11 2015-11-10 Google Inc. Reference frequency from ambient light signal
US9789655B1 (en) 2014-03-14 2017-10-17 Verily Life Sciences Llc Methods for mold release of body-mountable devices including microelectronics
CN106661224B (zh) 2014-08-26 2019-10-11 诺华股份有限公司 聚(噁唑啉-共-乙烯亚胺)-表氯醇共聚物及其用途
US10525170B2 (en) 2014-12-09 2020-01-07 Tangible Science, Llc Medical device coating with a biocompatible layer
EP3268804B1 (en) 2015-03-11 2020-11-04 University of Florida Research Foundation, Inc. Mesh size control of lubrication in gemini hydrogels
EP3279227B1 (en) * 2015-03-31 2019-08-07 Toray Industries, Inc. Separation membrane module for medical use, medical device using the same, and blood purifier
CA2992823C (en) 2015-09-04 2019-10-29 Novartis Ag Method for producing contact lenses with durable lubricious coatings thereon
AU2016364319B2 (en) 2015-12-03 2019-06-27 Alcon Inc. Contact lens packaging solutions
CN108367517A (zh) 2015-12-15 2018-08-03 诺华股份有限公司 用于生产具有润滑表面的接触镜片的方法
EP3845573B1 (en) * 2016-09-30 2023-08-09 Toray Industries, Inc. Copolymer and medical material containing the same
EP3532276B1 (en) 2016-10-31 2021-03-03 Alcon Inc. Method for producing surface coated contact lenses with wearing comfort
RU2766412C2 (ru) 2017-06-07 2022-03-15 Алькон Инк. Силикон-гидрогелевые контактные линзы
CA3062206C (en) 2017-06-07 2022-01-04 Alcon Inc. Silicone hydrogel contact lenses
TWI640557B (zh) * 2017-07-05 2018-11-11 晶碩光學股份有限公司 具表面修飾的隱形眼鏡及其製備方法
EP3447475B1 (en) 2017-08-24 2020-06-17 Alcon Inc. Method and apparatus for determining a coefficient of friction at a test site on a surface of a contact lens
TWI673315B (zh) * 2018-02-22 2019-10-01 優你康光學股份有限公司 具有釋放活性成分能力的水性組成物及可重複使用之隱形眼鏡產品
US20210132411A1 (en) 2019-11-04 2021-05-06 Alcon Inc. Contact lenses with surfaces having different softness
MX2022007311A (es) 2019-12-16 2022-07-12 Alcon Inc Lentes de contacto de hidrogel de silicona humectables.
CN111777909A (zh) * 2020-07-14 2020-10-16 浙江工业大学 一种通用的功能性聚合物涂层的制备方法
US20220032564A1 (en) 2020-07-28 2022-02-03 Alcon Inc. Contact lenses with softer lens surfaces
US20220372391A1 (en) 2021-04-22 2022-11-24 Alcon Inc. Method for applying a coating onto a non-silicone hydrogel lens
US20230103231A1 (en) 2021-09-01 2023-03-30 Alcon Inc. Method for producing wettable silicone hydrogel contact lenses
TW202334264A (zh) * 2022-02-21 2023-09-01 穎利科技股份有限公司 基材表面親水處理之方法及具親水改質表面之基材
US20240092043A1 (en) 2022-08-17 2024-03-21 Alcon Inc. Contact lens with a hydrogel coating thereon
CN115785800B (zh) * 2022-10-18 2023-07-11 广州市嵩达新材料科技有限公司 一种光固化导热涂层及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328340A2 (en) * 1988-02-09 1989-08-16 BAUSCH & LOMB INCORPORATED Hydrophilic oxygen permeable polymers
EP0338656A2 (en) * 1988-02-09 1989-10-25 BAUSCH & LOMB INCORPORATED Polymeric silicone-based materials with high oxygen permeability
WO1998028026A1 (en) * 1996-12-23 1998-07-02 Novartis Ag Reactive coatings
EP0989418A2 (en) * 1998-09-23 2000-03-29 JOHNSON & JOHNSON VISION PRODUCTS, INC. Wettable silicone-based lenses

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734475A (en) 1986-12-15 1988-03-29 Ciba-Geigy Corporation Wettable surface modified contact lens fabricated from an oxirane containing hydrophobic polymer
JPH02502134A (ja) * 1987-11-06 1990-07-12 エイエムオー プエルトリコ.インコーポレーテッド 表面層改質光学レンズと表面層改質方法
US5219965A (en) 1990-11-27 1993-06-15 Bausch & Lomb Incorporated Surface modification of polymer objects
GB9113875D0 (en) * 1991-06-27 1991-08-14 Biointeractions Ltd Polymer coatings
US5652014A (en) 1991-08-16 1997-07-29 Galin; Miles A. Medicament coated refractive anterior chamber ocular implant
US5352714A (en) 1991-11-05 1994-10-04 Bausch & Lomb Incorporated Wettable silicone hydrogel compositions and methods for their manufacture
JP3354571B2 (ja) * 1991-11-05 2002-12-09 ボシュ・アンド・ロム・インコーポレイテッド ぬれ性のシリコーンヒドロゲル組成物およびその製造方法
US5310779A (en) * 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5344701A (en) 1992-06-09 1994-09-06 Minnesota Mining And Manufacturing Company Porous supports having azlactone-functional surfaces
US5292514A (en) * 1992-06-24 1994-03-08 Minnesota Mining And Manufacturing Company Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof
US6087415A (en) * 1998-06-11 2000-07-11 Johnson & Johnson Vision Care, Inc. Biomedical devices with hydrophilic coatings
US6039913A (en) * 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328340A2 (en) * 1988-02-09 1989-08-16 BAUSCH & LOMB INCORPORATED Hydrophilic oxygen permeable polymers
EP0338656A2 (en) * 1988-02-09 1989-10-25 BAUSCH & LOMB INCORPORATED Polymeric silicone-based materials with high oxygen permeability
WO1998028026A1 (en) * 1996-12-23 1998-07-02 Novartis Ag Reactive coatings
EP0989418A2 (en) * 1998-09-23 2000-03-29 JOHNSON & JOHNSON VISION PRODUCTS, INC. Wettable silicone-based lenses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VALINT P L JR ET AL: "Surface-active macromonomers for coating of contact lens polymers", PROCEEDINGS OF THE 1997 SPRING ACS MEETING;SAN FRANCISCO, CA, USA APR 13-17 1997, vol. 76, 1997, Polym Mater Sci Eng Proc ACS Div Polym Mater Sci Eng;Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering 1997 ACS, Washington, D, pages 93 - 94, XP000931173 *

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858310B2 (en) 2000-04-03 2005-02-22 Bausch & Lomb Incorporated Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers
WO2001074932A1 (en) * 2000-04-03 2001-10-11 Bausch & Lomb Incorporated Surface treatment of silicone medical devices
WO2002024793A1 (en) * 2000-09-19 2002-03-28 Bausch & Lomb Incorporated Method for applying polymeric lens coating
KR100766642B1 (ko) * 2000-09-19 2007-10-15 보오슈 앤드 롬 인코포레이팃드 중합체 렌즈 코팅의 적용 방법
US6638563B2 (en) 2000-09-19 2003-10-28 Bausch & Lomb Incorporated Method for applying renewable polymeric lens coating
US7060288B2 (en) 2001-02-28 2006-06-13 Timothy Charles Hughes Biomedical devices
AU2002251029B2 (en) * 2001-02-28 2007-01-04 Commonwealth Scientific And Industrial Research Organisation Coated biomedical devices
WO2002068008A1 (en) * 2001-02-28 2002-09-06 Novartis Pharma Gmbh Coated biomedical devices
JP2004536633A (ja) * 2001-05-21 2004-12-09 ノバルティス アクチエンゲゼルシャフト 絡み合った親水性ポリマーを有するボトル−ブラシ型コーティング
EP1426809A4 (en) * 2001-08-17 2004-12-08 Johnson & Johnson Vision Care PROCESS FOR PRODUCING POLYMER FOR OPHTHALMIC LENSES AND CORRESPONDING OPHTHALMIC LENSES
EP1426809A1 (en) * 2001-08-17 2004-06-09 Johnson & Johnson Vision Care, Inc. Method for producing polymer for ophthalmic lens and ophthalmic lens
AU2001278757B2 (en) * 2001-08-17 2008-03-06 Johnson & Johnson Vision Care, Inc. Method for producing polymer for ophthalmic lens and ophthalmic lens
US7270678B2 (en) 2002-06-28 2007-09-18 Bausch & Lomb Incorporated Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
AU2003237998B2 (en) * 2002-06-28 2008-09-04 Bausch & Lomb Incorporated Intraocular lenses with modified surface
JP2006513282A (ja) * 2002-12-17 2006-04-20 ボシュ・アンド・ロム・インコーポレイテッド 医療用デバイスの表面処理
WO2007047716A2 (en) * 2005-10-19 2007-04-26 Bausch & Lomb Incorporated Surface-modified medical devices and method of making
WO2007047716A3 (en) * 2005-10-19 2007-09-20 Bausch & Lomb Surface-modified medical devices and method of making
WO2007064594A3 (en) * 2005-11-29 2007-07-19 Bausch & Lomb New coatings on ophthalmic lenses
WO2007064594A2 (en) * 2005-11-29 2007-06-07 Bausch & Lomb Incorporated New coatings on ophthalmic lenses
WO2008005752A2 (en) * 2006-06-30 2008-01-10 Bausch & Lomb Incorporated Modification of surfaces of polymeric articles by michael addition reaction
WO2008005752A3 (en) * 2006-06-30 2008-09-18 Bausch & Lomb Modification of surfaces of polymeric articles by michael addition reaction
US9738813B2 (en) 2010-07-30 2017-08-22 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US8944592B2 (en) 2010-07-30 2015-02-03 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
US9239409B2 (en) 2010-07-30 2016-01-19 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
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US10338408B2 (en) 2012-12-17 2019-07-02 Novartis Ag Method for making improved UV-absorbing ophthalmic lenses
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
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US11029447B2 (en) 2017-12-13 2021-06-08 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses

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