WO2000047222A3 - Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation - Google Patents
Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation Download PDFInfo
- Publication number
- WO2000047222A3 WO2000047222A3 PCT/AT2000/000023 AT0000023W WO0047222A3 WO 2000047222 A3 WO2000047222 A3 WO 2000047222A3 AT 0000023 W AT0000023 W AT 0000023W WO 0047222 A3 WO0047222 A3 WO 0047222A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- influenza virus
- nasal
- oral administration
- virus vaccine
- inactivated influenza
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT00903423T ATE395929T1 (de) | 1999-02-11 | 2000-02-01 | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
AU25253/00A AU770923B2 (en) | 1999-02-11 | 2000-02-01 | Inactivated influenza virus vaccine for nasal or oral administration |
DE50015170T DE50015170D1 (de) | 1999-02-11 | 2000-02-01 | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
US09/913,400 US6635246B1 (en) | 1999-02-11 | 2000-02-01 | Inactivated influenza virus vaccine for nasal or oral application |
EP00903423A EP1144001B1 (de) | 1999-02-11 | 2000-02-01 | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
DK00903423T DK1144001T3 (da) | 1999-02-11 | 2000-02-01 | Inaktiveret influenzavirusvaccine til nasal eller oral indgivelse |
US11/027,936 US7052701B2 (en) | 1999-02-11 | 2005-01-04 | Inactivated influenza virus vaccine for nasal or oral application |
US11/365,836 US20060147468A1 (en) | 1999-02-11 | 2006-03-02 | Inactivated influenza virus vaccine for nasal or oral application |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0019499A AT407958B (de) | 1999-02-11 | 1999-02-11 | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
ATA194/99 | 1999-02-11 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09913400 A-371-Of-International | 2000-02-01 | ||
US09/913,400 A-371-Of-International US6635246B1 (en) | 1999-02-11 | 2000-02-01 | Inactivated influenza virus vaccine for nasal or oral application |
US10/639,449 Continuation US6861244B2 (en) | 1999-02-11 | 2003-08-13 | Inactivated influenza virus vaccine for nasal or oral application |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000047222A2 WO2000047222A2 (de) | 2000-08-17 |
WO2000047222A3 true WO2000047222A3 (de) | 2001-10-11 |
Family
ID=3483987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AT2000/000023 WO2000047222A2 (de) | 1999-02-11 | 2000-02-01 | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
Country Status (10)
Country | Link |
---|---|
US (4) | US6635246B1 (de) |
EP (1) | EP1144001B1 (de) |
AT (2) | AT407958B (de) |
AU (1) | AU770923B2 (de) |
CY (1) | CY1108272T1 (de) |
DE (1) | DE50015170D1 (de) |
DK (1) | DK1144001T3 (de) |
ES (1) | ES2307494T3 (de) |
PT (1) | PT1144001E (de) |
WO (1) | WO2000047222A2 (de) |
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ATE376825T1 (de) * | 1999-09-24 | 2007-11-15 | Glaxosmithkline Biolog Sa | Influenzavirus-impfstoffzusammensetzung zur nasalen anwendung |
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US20030092145A1 (en) * | 2000-08-24 | 2003-05-15 | Vic Jira | Viral vaccine composition, process, and methods of use |
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DE202005022108U1 (de) | 2004-03-09 | 2013-11-12 | Novartis Vaccines And Diagnostics, Inc. | Influenza-Virus-Impfstoffe |
ES2694123T3 (es) | 2004-06-01 | 2018-12-18 | Icahn School Of Medicine At Mount Sinai | Virus de la gripe porcina modificado por ingeniería genética y usos de los mismos |
WO2006088481A2 (en) * | 2005-02-15 | 2006-08-24 | Mount Sinai School Of Medicine Of New York University | Genetically engineered equine influenza virus and uses thereof |
PT1861120T (pt) | 2005-03-23 | 2016-08-18 | Glaxosmithkline Biologicals Sa | Utilização de um vírus influenza e de um adjuvante de emulsão óleo-em-água para induzir células t cd4 e/ou melhorar a resposta de células b de memória |
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MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
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US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
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KR100850545B1 (ko) * | 2007-10-30 | 2008-08-05 | 주식회사 에니멀제네틱스 | 신규한 개 인플루엔자 바이러스 및 이의 백신 |
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US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
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CN101524537B (zh) * | 2009-03-26 | 2012-11-28 | 成都康华生物制品有限公司 | 流感口服含片疫苗、流感口服缓释疫苗以及二者制备方法 |
EP2413962A1 (de) | 2009-03-30 | 2012-02-08 | Mount Sinai School of Medicine | Impfstoffe gegen das grippevirus und ihre verwendungen |
CA2803282C (en) | 2009-07-06 | 2018-05-01 | David E. Anderson | Methods for preparing vesicles and formulations produced therefrom |
US9849173B2 (en) | 2009-07-06 | 2017-12-26 | Variation Biotechnologies Inc. | Methods for preparing vesicles and formulations produced therefrom |
WO2011014504A1 (en) | 2009-07-27 | 2011-02-03 | Mount Sinai School Of Medicine Of New York University | Recombinant influenza virus vectors and uses thereof |
US8828406B2 (en) | 2009-07-30 | 2014-09-09 | Icahn School Of Medicine At Mount Sinai | Influenza viruses and uses thereof |
US20110110975A1 (en) * | 2009-11-06 | 2011-05-12 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
BR112012022059B1 (pt) * | 2010-03-02 | 2021-07-27 | Applied Medical Enzyme Research Institute Corporation | Vacina de mucosa produtora de uma iga de mucosa antígenoespecífica e igg do sangue e método para produzir uma vacina de mucosa |
CA2792537A1 (en) | 2010-03-30 | 2011-10-06 | Mount Sinai School Of Medicine | Influenza virus vaccines and uses thereof |
AU2011276223C1 (en) | 2010-07-06 | 2016-05-12 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
MX359103B (es) | 2011-01-13 | 2018-09-14 | Variation Biotechnologies Inc | Composiciones y sus usos en el tratamiento de infecciones virales. |
EP2663288B1 (de) | 2011-01-13 | 2022-12-21 | Variation Biotechnologies Inc. | Verfahren zur vesikelherstellung und darin hergestellte formulierungen |
WO2012151391A2 (en) | 2011-05-04 | 2012-11-08 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
US9492525B2 (en) | 2011-07-06 | 2016-11-15 | Nanobio Corporation | Human respiratory syncytial virus vaccine |
US20130189303A1 (en) | 2011-08-02 | 2013-07-25 | Yan Zhou | Recombinant swine influenza virus and uses thereof |
EP3329936A1 (de) | 2011-08-22 | 2018-06-06 | Nanobio Corporation | Impfstoff gegen den herpes-simplex-virus als nanoemulsion |
EP2758075B1 (de) | 2011-09-20 | 2023-05-03 | Icahn School of Medicine at Mount Sinai | Influenzavirus-impfstoffe und verwendungen davon |
EP2780350B1 (de) | 2011-11-18 | 2019-03-06 | Variation Biotechnologies Inc. | Synthetische mpl-derivate und ihre verwendung |
CN104302323A (zh) | 2012-01-12 | 2015-01-21 | 变异生物技术公司 | 用于治疗病毒感染的组合物和方法 |
RU2698906C2 (ru) | 2012-01-27 | 2019-09-02 | Вэриэйшн Биотекнолоджиз, Инк. | Способы и композиции для терапевтических агентов |
JP2016508133A (ja) | 2012-12-18 | 2016-03-17 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン及びその使用 |
WO2014164699A1 (en) * | 2013-03-11 | 2014-10-09 | The Regents Of The University Of California | Herpes virus vaccines and treatments |
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JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
CN107250353B (zh) | 2015-02-26 | 2021-07-23 | 勃林格殷格翰动物保健有限公司 | 二价猪流感病毒疫苗 |
EP3471767A4 (de) | 2016-06-15 | 2020-01-15 | Icahn School of Medicine at Mount Sinai | Influenzavirus-hämagglutinin-proteine und verwendungen davon |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
EP3606555A4 (de) | 2017-04-07 | 2021-08-04 | Icahn School of Medicine at Mount Sinai | Neuraminidase-antikörper gegen influenza-b-virus und verwendungen davon |
US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
US20220370605A1 (en) | 2019-10-08 | 2022-11-24 | Luxembourg Institute Of Health (Lih) | Inhibitor of DJ-1 for Use in Treating Immunoaging |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994019013A1 (en) * | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a |
WO1996040290A1 (en) * | 1995-06-07 | 1996-12-19 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
WO1997049423A2 (en) * | 1996-06-24 | 1997-12-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal influenza vaccine composition and method |
WO1999024068A1 (en) * | 1997-11-10 | 1999-05-20 | Michigan State University | Immortal avian cell line to grow avian and animal viruses to produce vaccines |
WO2000015251A2 (de) * | 1998-09-15 | 2000-03-23 | Baxter Aktiengesellschaft | Influenzavirus-impfstoffzusammensetzung |
Family Cites Families (10)
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JPS62201574A (ja) * | 1986-02-27 | 1987-09-05 | Shionogi & Co Ltd | 家禽用インフルエンザワクチン |
US4981782A (en) * | 1987-05-14 | 1991-01-01 | Sri International | Synthetic peptides for diagnosis and prevention of influenza virus infection and their use |
US5136019A (en) * | 1989-05-24 | 1992-08-04 | Sri International | Synthetic peptides for diagnosis and prevention of influenza virus infection and their use |
US5243030A (en) * | 1989-05-24 | 1993-09-07 | Sri International | Conjugates of a synthetic peptide for diagnosis and prevention of influenza virus infection |
US5562909A (en) * | 1993-07-12 | 1996-10-08 | Massachusetts Institute Of Technology | Phosphazene polyelectrolytes as immunoadjuvants |
US5976552A (en) * | 1995-04-28 | 1999-11-02 | Protein Sciences Corporation | Virus vaccines |
JP3158157B2 (ja) * | 1994-11-10 | 2001-04-23 | バクスター・アクチエンゲゼルシャフト | 無蛋白培養における生物製剤の製造法 |
US6949244B1 (en) * | 1995-12-20 | 2005-09-27 | The Board Of Trustees Of The University Of Kentucky | Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof |
US5690942A (en) * | 1995-06-02 | 1997-11-25 | American Home Products Corporation | Adjuvants for viral vaccines |
AT407958B (de) | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
-
1999
- 1999-02-11 AT AT0019499A patent/AT407958B/de not_active IP Right Cessation
-
2000
- 2000-02-01 US US09/913,400 patent/US6635246B1/en not_active Expired - Lifetime
- 2000-02-01 AU AU25253/00A patent/AU770923B2/en not_active Expired
- 2000-02-01 WO PCT/AT2000/000023 patent/WO2000047222A2/de active IP Right Grant
- 2000-02-01 PT PT00903423T patent/PT1144001E/pt unknown
- 2000-02-01 AT AT00903423T patent/ATE395929T1/de active
- 2000-02-01 ES ES00903423T patent/ES2307494T3/es not_active Expired - Lifetime
- 2000-02-01 EP EP00903423A patent/EP1144001B1/de not_active Expired - Lifetime
- 2000-02-01 DE DE50015170T patent/DE50015170D1/de not_active Expired - Lifetime
- 2000-02-01 DK DK00903423T patent/DK1144001T3/da active
-
2003
- 2003-08-13 US US10/639,449 patent/US6861244B2/en not_active Expired - Lifetime
-
2005
- 2005-01-04 US US11/027,936 patent/US7052701B2/en not_active Expired - Lifetime
-
2006
- 2006-03-02 US US11/365,836 patent/US20060147468A1/en not_active Abandoned
-
2008
- 2008-08-20 CY CY20081100884T patent/CY1108272T1/el unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994019013A1 (en) * | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a |
WO1996040290A1 (en) * | 1995-06-07 | 1996-12-19 | Connaught Laboratories, Inc. | Immunological combination compositions and methods |
WO1997049423A2 (en) * | 1996-06-24 | 1997-12-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Liposomal influenza vaccine composition and method |
WO1999024068A1 (en) * | 1997-11-10 | 1999-05-20 | Michigan State University | Immortal avian cell line to grow avian and animal viruses to produce vaccines |
WO2000015251A2 (de) * | 1998-09-15 | 2000-03-23 | Baxter Aktiengesellschaft | Influenzavirus-impfstoffzusammensetzung |
Non-Patent Citations (1)
Title |
---|
AVTUSHENKO S S ET AL: "Clinical and immunological characteristics of the emulsion form of inactivated influenza vaccine delivered by oral immunization", JOURNAL OF BIOTECHNOLOGY,NL,ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, vol. 44, no. 1, 26 January 1996 (1996-01-26), pages 21 - 28, XP004036844, ISSN: 0168-1656 * |
Also Published As
Publication number | Publication date |
---|---|
ATE395929T1 (de) | 2008-06-15 |
US20040096464A1 (en) | 2004-05-20 |
US7052701B2 (en) | 2006-05-30 |
EP1144001B1 (de) | 2008-05-21 |
US20060147468A1 (en) | 2006-07-06 |
US6635246B1 (en) | 2003-10-21 |
AU2525300A (en) | 2000-08-29 |
EP1144001A2 (de) | 2001-10-17 |
WO2000047222A2 (de) | 2000-08-17 |
DE50015170D1 (de) | 2008-07-03 |
DK1144001T3 (da) | 2008-09-15 |
PT1144001E (pt) | 2008-08-29 |
US20050196413A1 (en) | 2005-09-08 |
ES2307494T3 (es) | 2008-12-01 |
AU770923B2 (en) | 2004-03-11 |
AT407958B (de) | 2001-07-25 |
ATA19499A (de) | 2000-12-15 |
US6861244B2 (en) | 2005-03-01 |
CY1108272T1 (el) | 2014-02-12 |
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