WO2000009709A3 - Proteases et proteines associees - Google Patents

Proteases et proteines associees Download PDF

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Publication number
WO2000009709A3
WO2000009709A3 PCT/US1999/017818 US9917818W WO0009709A3 WO 2000009709 A3 WO2000009709 A3 WO 2000009709A3 US 9917818 W US9917818 W US 9917818W WO 0009709 A3 WO0009709 A3 WO 0009709A3
Authority
WO
WIPO (PCT)
Prior art keywords
pprg
associated proteins
proteases
provides
expression
Prior art date
Application number
PCT/US1999/017818
Other languages
English (en)
Other versions
WO2000009709A2 (fr
Inventor
Olga Bandman
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Karl J Guegler
Neil C Corley
Henry Yue
Y Tom Tang
Roopa Reddy
Chandra Patterson
Janice Au-Young
Leo L Shih
Dyung Aina M Lu
Original Assignee
Incyte Pharma Inc
Olga Bandman
Jennifer L Hillman
Mariah R Baughn
Yalda Azimzai
Karl J Guegler
Neil C Corley
Henry Yue
Y Tom Tang
Roopa Reddy
Chandra Patterson
Au Young Janice
Leo L Shih
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Olga Bandman, Jennifer L Hillman, Mariah R Baughn, Yalda Azimzai, Karl J Guegler, Neil C Corley, Henry Yue, Y Tom Tang, Roopa Reddy, Chandra Patterson, Au Young Janice, Leo L Shih, Dyung Aina M Lu filed Critical Incyte Pharma Inc
Priority to EP99939042A priority Critical patent/EP1104473A2/fr
Priority to AU53403/99A priority patent/AU5340399A/en
Priority to CA002338386A priority patent/CA2338386A1/fr
Priority to JP2000565144A priority patent/JP2002522081A/ja
Publication of WO2000009709A2 publication Critical patent/WO2000009709A2/fr
Publication of WO2000009709A3 publication Critical patent/WO2000009709A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des protéases et des protéines humaines associées (PRRG) ainsi que des polynucléotides identifiant et codant les PRRG. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne aussi des procédés pour diagnostiquer, traiter ou prévenir les maladies liées à l'expression des PRRG.
PCT/US1999/017818 1998-08-10 1999-08-06 Proteases et proteines associees WO2000009709A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99939042A EP1104473A2 (fr) 1998-08-10 1999-08-06 Proteases et proteines associees
AU53403/99A AU5340399A (en) 1998-08-10 1999-08-06 Proteases and associated proteins
CA002338386A CA2338386A1 (fr) 1998-08-10 1999-08-06 Proteases et proteines associees
JP2000565144A JP2002522081A (ja) 1998-08-10 1999-08-06 プロテアーゼ及び関連タンパク質

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9611498P 1998-08-10 1998-08-10
US60/096,114 1998-08-10
US11976899P 1999-02-11 1999-02-11
US60/119,768 1999-02-11

Publications (2)

Publication Number Publication Date
WO2000009709A2 WO2000009709A2 (fr) 2000-02-24
WO2000009709A3 true WO2000009709A3 (fr) 2000-09-08

Family

ID=26791134

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017818 WO2000009709A2 (fr) 1998-08-10 1999-08-06 Proteases et proteines associees

Country Status (5)

Country Link
EP (1) EP1104473A2 (fr)
JP (1) JP2002522081A (fr)
AU (1) AU5340399A (fr)
CA (1) CA2338386A1 (fr)
WO (1) WO2000009709A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919433B2 (en) 1997-03-14 2005-07-19 Human Genome Sciences, Inc. Antibodies to protein HPMBQ91
US6951924B2 (en) 1997-03-14 2005-10-04 Human Genome Sciences, Inc. Antibodies against secreted protein HTEBYII
JP2001524814A (ja) 1997-03-14 2001-12-04 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ２８種類のヒト分泌タンパク質
JP2002532054A (ja) 1997-08-29 2002-10-02 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ２９個のヒト分泌タンパク質
WO1999058668A1 (fr) * 1998-05-14 1999-11-18 Ono Pharmaceutical Co., Ltd. Nouveaux polypeptides, adn complementaires les codant et utilisation de ces polypeptides
EP1080209A2 (fr) * 1998-10-21 2001-03-07 Arch Development Corporation Procede de traitement des diabetes de type 2
JP2003125777A (ja) * 1999-04-27 2003-05-07 Jenokkusu Soyaku Kenkyusho:Kk 花粉症関連遺伝子、５８１
EP1238281A2 (fr) * 1999-12-01 2002-09-11 Ludwig Institute For Cancer Research Antigenes associes au cancer et utilisations correspondantes
WO2001064919A2 (fr) * 2000-02-28 2001-09-07 Millennium Pharmaceuticals, Inc. 18036, une nouvelle protease semblable a la calpaïne, et utilisations de celle-la
WO2001088157A2 (fr) * 2000-05-16 2001-11-22 Millennium Pharmaceuticals, Inc. Methodes de traitement avec 17906 et utilisations de celles-ci
JP2004523212A (ja) * 2000-09-08 2004-08-05 インサイト・ゲノミックス・インコーポレイテッド プロテアーゼ
WO2002026955A2 (fr) * 2000-09-29 2002-04-04 Lexicon Genetics Incorporated Nouvelles proteases humaines et polynucleotides codant pour ces proteases
WO2002053754A2 (fr) * 2001-01-08 2002-07-11 Lexicon Genetics Incorporated Nouvelle protease humaine et polynucleotides codant cette derniere
EP1532161B1 (fr) 2002-06-13 2012-02-15 Novartis Vaccines and Diagnostics, Inc. Vecteurs pour l'expression de polypeptides hml-2
WO2004104218A1 (fr) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Agents diagnostiques et therapeutiques destines a des maladies associees a x-prolyl aminopeptidase 1 (xpnpep1)
WO2008012476A2 (fr) * 2006-07-26 2008-01-31 L'oreal Utilisation de carboxypeptidases dans le domaine cosmetique et therapeutique
FR2904223B1 (fr) * 2006-07-26 2013-01-11 Oreal Utilisation de carboxypeptidases dans le domaine cosmetique et therapeutique
DE102009010942A1 (de) * 2009-02-27 2010-09-02 Universitätsklinikum Schleswig-Holstein Serinprotease-Inhibitoren zur spezifischen Inhibition von Gewebs-Kallikreinen
JP5728743B2 (ja) * 2009-03-30 2015-06-03 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 関節リウマチの診断のためのバイオマーカー、方法およびキット

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004387A1 (fr) * 1994-08-02 1996-02-15 Roussel Uclaf Sequences d'adn codant pour les proteines humaines tx et ty apparentees a l'enzyme de conversion de l'interleukine-1beta

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004387A1 (fr) * 1994-08-02 1996-02-15 Roussel Uclaf Sequences d'adn codant pour les proteines humaines tx et ty apparentees a l'enzyme de conversion de l'interleukine-1beta

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERNOT ET AL.: "A transcriptional map of the FMF region", GENOMICS, vol. 50, 1998, pages 147 - 160, XP002090815 *
BERNOT ET AL.: "Homo sapiens mRNA for metalloproteinase", EMBL SEQUENCE DATABASE, 21 January 1998 (1998-01-21), HEIDELBERG DE, XP002129491 *
BERNOT ET AL.: "Metalloproteinase", EMBL SEQUENCE DATABASE, 1 June 1998 (1998-06-01), HEIDELBERG DE, XP002129490 *

Also Published As

Publication number Publication date
CA2338386A1 (fr) 2000-02-24
JP2002522081A (ja) 2002-07-23
WO2000009709A2 (fr) 2000-02-24
AU5340399A (en) 2000-03-06
EP1104473A2 (fr) 2001-06-06

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