WO2000028045A3 - Hydrolases humaines - Google Patents

Hydrolases humaines Download PDF

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Publication number
WO2000028045A3
WO2000028045A3 PCT/US1999/027009 US9927009W WO0028045A3 WO 2000028045 A3 WO2000028045 A3 WO 2000028045A3 US 9927009 W US9927009 W US 9927009W WO 0028045 A3 WO0028045 A3 WO 0028045A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrl
hydrolase proteins
human hydrolase
provides
human
Prior art date
Application number
PCT/US1999/027009
Other languages
English (en)
Other versions
WO2000028045A2 (fr
Inventor
Tom Y Tang
Jennifer L Hillman
Henry Yue
Preeti Lal
Olga Bandman
Neil C Corley
Karl J Guegler
Mariah R Baughn
Dyung Aina M Lu
Yalda Azimzai
Junming Yang
Original Assignee
Incyte Pharma Inc
Tom Y Tang
Jennifer L Hillman
Henry Yue
Preeti Lal
Olga Bandman
Neil C Corley
Karl J Guegler
Mariah R Baughn
Dyung Aina M Lu
Yalda Azimzai
Junming Yang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Tom Y Tang, Jennifer L Hillman, Henry Yue, Preeti Lal, Olga Bandman, Neil C Corley, Karl J Guegler, Mariah R Baughn, Dyung Aina M Lu, Yalda Azimzai, Junming Yang filed Critical Incyte Pharma Inc
Priority to CA002350388A priority Critical patent/CA2350388A1/fr
Priority to JP2000581212A priority patent/JP2003528567A/ja
Priority to EP99962774A priority patent/EP1131443A2/fr
Priority to AU19144/00A priority patent/AU1914400A/en
Publication of WO2000028045A2 publication Critical patent/WO2000028045A2/fr
Publication of WO2000028045A3 publication Critical patent/WO2000028045A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

L'invention concerne des hydrolases humaines (HYDRL), ainsi que des polynucléotides identifiant et codant pour HYDRL. Elle se rapporte également à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes, et propose des méthodes de diagnostique, de traitement ou de prévention de troubles associés à l'expression de HYDRL.
PCT/US1999/027009 1998-11-12 1999-11-12 Hydrolases humaines WO2000028045A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002350388A CA2350388A1 (fr) 1998-11-12 1999-11-12 Hydrolases humaines
JP2000581212A JP2003528567A (ja) 1998-11-12 1999-11-12 ヒトヒドロラーゼタンパク質
EP99962774A EP1131443A2 (fr) 1998-11-12 1999-11-12 Hydrolases humaines
AU19144/00A AU1914400A (en) 1998-11-12 1999-11-12 Human hydrolase proteins

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17225698P 1998-11-12 1998-11-12
US60/172,256 1998-11-12
US13551999P 1999-05-21 1999-05-21
US60/135,519 1999-05-21

Publications (2)

Publication Number Publication Date
WO2000028045A2 WO2000028045A2 (fr) 2000-05-18
WO2000028045A3 true WO2000028045A3 (fr) 2000-10-26

Family

ID=26833410

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/027009 WO2000028045A2 (fr) 1998-11-12 1999-11-12 Hydrolases humaines

Country Status (5)

Country Link
EP (1) EP1131443A2 (fr)
JP (1) JP2003528567A (fr)
AU (1) AU1914400A (fr)
CA (1) CA2350388A1 (fr)
WO (1) WO2000028045A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1144605B1 (fr) * 1999-01-26 2009-12-16 University College London Dimethylarginine dimethylaminohydrolases
AU3097301A (en) * 2000-01-19 2001-07-31 University Of Virginia Patent Foundation Sperm specific lysozyme-like proteins
US7125550B2 (en) 2000-01-19 2006-10-24 University Of Virginia Patent Foundation Human sperm specific lysozyme-like proteins
US20020038010A1 (en) * 2000-02-11 2002-03-28 Yi Hu Novel human lysozymes and polynucleotides encoding the same
US6500657B1 (en) * 2000-03-31 2002-12-31 Millennium Pharmaceuticals, Inc. 33167, a novel human hydrolase and uses therefor
WO2002002760A2 (fr) * 2000-06-29 2002-01-10 Millennium Pharmaceuticals, Inc. 25869, nouvelle carboxylesterase humaine et ses utilisations
EP1358339A2 (fr) * 2000-07-21 2003-11-05 Millennium Pharmaceuticals, Inc. 56939, un nouveau membre de la famille humaine des acyl-coa thioesterases et son utilisation
WO2002026998A2 (fr) * 2000-09-29 2002-04-04 Incyte Genomics, Inc. Hydrolases
AR088699A1 (es) * 2011-11-09 2014-06-25 Sanofi Sa Diacilglicerol lipasa y usos de la misma

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0811687A2 (fr) * 1996-06-07 1997-12-10 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptides avec une activité de L-asparaginase
WO1998000553A1 (fr) * 1996-07-03 1998-01-08 Incyte Pharmaceuticals, Inc. Hyaluronidase humaine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0811687A2 (fr) * 1996-06-07 1997-12-10 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptides avec une activité de L-asparaginase
WO1998000553A1 (fr) * 1996-07-03 1998-01-08 Incyte Pharmaceuticals, Inc. Hyaluronidase humaine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 11 August 1997 (1997-08-11), GRAFHAM D: "Human DNA sequence from clone 54B20 on chromosome Xp11.1-11.3", XP002133630 *
DATABASE EMBL 2 December 1991 (1991-12-02), SWANSON KW ET AL: "C. aethiops mRNA for lysozyme", XP002133631 *

Also Published As

Publication number Publication date
AU1914400A (en) 2000-05-29
WO2000028045A2 (fr) 2000-05-18
EP1131443A2 (fr) 2001-09-12
JP2003528567A (ja) 2003-09-30
CA2350388A1 (fr) 2000-05-18

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