WO2000023589A3 - Proteines associees a la proliferation et a l'apoptose - Google Patents

Proteines associees a la proliferation et a l'apoptose Download PDF

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Publication number
WO2000023589A3
WO2000023589A3 PCT/US1999/024511 US9924511W WO0023589A3 WO 2000023589 A3 WO2000023589 A3 WO 2000023589A3 US 9924511 W US9924511 W US 9924511W WO 0023589 A3 WO0023589 A3 WO 0023589A3
Authority
WO
WIPO (PCT)
Prior art keywords
related proteins
proliferation
proap
apoptosis related
provides
Prior art date
Application number
PCT/US1999/024511
Other languages
English (en)
Other versions
WO2000023589A2 (fr
Inventor
Y Tom Tang
Henry Yue
Jennifer L Hillman
Karl J Guegler
Neil C Corley
Preeti Lal
Yalda Azimzai
Mariah R Baughn
Junming Yang
Leo L Shih
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Henry Yue
Jennifer L Hillman
Karl J Guegler
Neil C Corley
Preeti Lal
Yalda Azimzai
Mariah R Baughn
Junming Yang
Leo L Shih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Henry Yue, Jennifer L Hillman, Karl J Guegler, Neil C Corley, Preeti Lal, Yalda Azimzai, Mariah R Baughn, Junming Yang, Leo L Shih filed Critical Incyte Pharma Inc
Priority to CA002347836A priority Critical patent/CA2347836A1/fr
Priority to JP2000577298A priority patent/JP2003524382A/ja
Priority to AU11260/00A priority patent/AU1126000A/en
Priority to EP99955070A priority patent/EP1123394A2/fr
Publication of WO2000023589A2 publication Critical patent/WO2000023589A2/fr
Publication of WO2000023589A3 publication Critical patent/WO2000023589A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des protéines associées à la prolifération humaine et à l'apoptose (PROAP) et des polynucléotides qui identifient et codent PROAP. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne en outre des méthodes pour diagnostiquer, traiter ou prévenir des troubles liés à l'expression de PROAP.
PCT/US1999/024511 1998-10-20 1999-10-19 Proteines associees a la proliferation et a l'apoptose WO2000023589A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002347836A CA2347836A1 (fr) 1998-10-20 1999-10-19 Proteines associees a la proliferation et a l'apoptose
JP2000577298A JP2003524382A (ja) 1999-02-04 1999-10-19 細胞増殖及びアポトーシス関連タンパク質
AU11260/00A AU1126000A (en) 1998-10-20 1999-10-19 Proliferation and apoptosis related proteins
EP99955070A EP1123394A2 (fr) 1998-10-20 1999-10-19 Proteines associees a la proliferation et a l'apoptose

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US17221698P 1998-10-20 1998-10-20
US60/172,216 1999-01-19
US11855999P 1999-02-04 1999-02-04
US60/118,559 1999-02-04
US17222999P 1999-02-11 1999-02-11
US60/172,229 1999-02-11
US15433699P 1999-04-22 1999-04-22
US60/154,336 1999-04-22

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09807452 A-371-Of-International 2001-04-11
US10/839,882 Division US20040203106A1 (en) 1999-01-19 2004-05-05 Signal peptide-containing molecules

Publications (2)

Publication Number Publication Date
WO2000023589A2 WO2000023589A2 (fr) 2000-04-27
WO2000023589A3 true WO2000023589A3 (fr) 2000-09-28

Family

ID=27494206

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/024511 WO2000023589A2 (fr) 1998-10-20 1999-10-19 Proteines associees a la proliferation et a l'apoptose

Country Status (4)

Country Link
EP (1) EP1123394A2 (fr)
AU (1) AU1126000A (fr)
CA (1) CA2347836A1 (fr)
WO (1) WO2000023589A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5544500A (en) 1999-06-15 2001-01-02 Astrazeneca Ab Livin; inhibitor-of-apoptosis protein-3 (iap-3)
EP1103608A1 (fr) * 1999-11-25 2001-05-30 Sanofi-Synthelabo Protéine de type CIDE , son isolation et ses applications
AU2001294267A1 (en) * 2000-10-17 2002-04-29 Takeda Chemical Industries Ltd. Survivin-like polypeptides and dnas thereof
US7317085B2 (en) * 2001-01-22 2008-01-08 Shinae Kondoh Human apoptosis-associated genes and human apoptosis-associated proteins produced thereby
US20030044814A1 (en) * 2001-02-08 2003-03-06 Tularik Inc. PRC17: an amplified cancer gene
US20030224486A1 (en) * 2001-04-19 2003-12-04 Julie Carman Polynucleotides and polypeptides associated with the NF-kB pathway
EP1365242A1 (fr) * 2002-05-21 2003-11-26 MTM Laboratories AG Composés pour le diagnostique et le traitement de lésions colorectales
EP2114420B1 (fr) 2007-02-16 2016-01-27 Virttu Biologics Limited Virus de l'herpès simplex et procédés de réplication virale
WO2023178241A2 (fr) * 2022-03-16 2023-09-21 The Regents Of The University Of Colorado A Body Corporate Procédés et compositions pour perturber des agrégats de tau à l'aide de séquences de répétition de polysérine ciblant des protéines exogènes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045128A1 (fr) * 1996-05-29 1997-12-04 Apoptosis Technology, Inc. Proteine bbk associee a l'apoptose
WO1998005347A1 (fr) * 1996-07-22 1998-02-12 The Trustees Of Columbia University In The City Of New York Composes inhibiteurs de l'interaction entre proteines transductrices de signaux et le domaine glgf (pdz/dhr), et utilisation de tels composes
WO1998011256A1 (fr) * 1996-09-13 1998-03-19 The Trustees Of Columbia University In The City Ofnew York Becline, un nouveau gene en interaction avec bcl-2 proche de brca1 sur le chromosome 17q21 et procedes d'utilisation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997045128A1 (fr) * 1996-05-29 1997-12-04 Apoptosis Technology, Inc. Proteine bbk associee a l'apoptose
WO1998005347A1 (fr) * 1996-07-22 1998-02-12 The Trustees Of Columbia University In The City Of New York Composes inhibiteurs de l'interaction entre proteines transductrices de signaux et le domaine glgf (pdz/dhr), et utilisation de tels composes
WO1998011256A1 (fr) * 1996-09-13 1998-03-19 The Trustees Of Columbia University In The City Ofnew York Becline, un nouveau gene en interaction avec bcl-2 proche de brca1 sur le chromosome 17q21 et procedes d'utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DESBARATS, L. ET AL.: "Myc: a single gene controls both proliferation and apoptosis in mammalian cells", EXPERIENTIA, vol. 15, no. 52, December 1996 (1996-12-01), pages 1123 - 1129, XP000882427 *
GALIANA E ET AL: "Identification of a neural-specific cDNA, NPDC-1, able to down-regulate cell proliferation and to suppress transformation.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (1995 FEB 28) 92 (5) 1560-4., XP002133326 *

Also Published As

Publication number Publication date
EP1123394A2 (fr) 2001-08-16
WO2000023589A2 (fr) 2000-04-27
AU1126000A (en) 2000-05-08
CA2347836A1 (fr) 2000-04-27

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