WO2000026245A3 - Proteines de transport membranaire - Google Patents

Proteines de transport membranaire Download PDF

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Publication number
WO2000026245A3
WO2000026245A3 PCT/US1999/026048 US9926048W WO0026245A3 WO 2000026245 A3 WO2000026245 A3 WO 2000026245A3 US 9926048 W US9926048 W US 9926048W WO 0026245 A3 WO0026245 A3 WO 0026245A3
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WO
WIPO (PCT)
Prior art keywords
transport proteins
membrane transport
human membrane
mtrp
provides
Prior art date
Application number
PCT/US1999/026048
Other languages
English (en)
Other versions
WO2000026245A2 (fr
Inventor
Jennifer L Hillman
Henry Yue
Y Tom Tang
Preeti Lal
Neil C Corley
Karl J Guegler
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Henry Yue
Y Tom Tang
Preeti Lal
Neil C Corley
Karl J Guegler
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Henry Yue, Y Tom Tang, Preeti Lal, Neil C Corley, Karl J Guegler, Mariah R Baughn, Yalda Azimzai, Dyung Aina M Lu filed Critical Incyte Pharma Inc
Priority to CA002349818A priority Critical patent/CA2349818A1/fr
Priority to AU16068/00A priority patent/AU1606800A/en
Priority to EP99958774A priority patent/EP1144443A3/fr
Priority to JP2000579632A priority patent/JP2003521227A/ja
Publication of WO2000026245A2 publication Critical patent/WO2000026245A2/fr
Publication of WO2000026245A3 publication Critical patent/WO2000026245A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P7/06—Antianaemics
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    • A61P9/06—Antiarrhythmics
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

L'invention concerne des protéines humaines de transport membranaire (MTRP) et des polynucléotides qui identifient et codent MTRP. L'invention concerne aussi des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention se rapporte en outre à un procédé de diagnostic, de traitement ou de prévention de troubles associés à l'expression de MTRP.
PCT/US1999/026048 1998-11-04 1999-11-04 Proteines de transport membranaire WO2000026245A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002349818A CA2349818A1 (fr) 1998-11-04 1999-11-04 Proteines de transport membranaire
AU16068/00A AU1606800A (en) 1998-11-04 1999-11-04 Membrane transport proteins
EP99958774A EP1144443A3 (fr) 1998-11-04 1999-11-04 Proteines de transport membranaire
JP2000579632A JP2003521227A (ja) 1998-11-04 1999-11-04 膜輸送タンパク質

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US17225598P 1998-11-04 1998-11-04
US60/172,255 1998-11-04
US17225298P 1998-11-24 1998-11-24
US60/172,252 1998-11-24
US17221498P 1998-12-22 1998-12-22
US60/172,214 1998-12-22
US12189699P 1999-02-26 1999-02-26
US60/121,896 1999-02-26

Publications (2)

Publication Number Publication Date
WO2000026245A2 WO2000026245A2 (fr) 2000-05-11
WO2000026245A3 true WO2000026245A3 (fr) 2001-04-19

Family

ID=27494391

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/026048 WO2000026245A2 (fr) 1998-11-04 1999-11-04 Proteines de transport membranaire

Country Status (5)

Country Link
EP (1) EP1144443A3 (fr)
JP (1) JP2003521227A (fr)
AU (1) AU1606800A (fr)
CA (1) CA2349818A1 (fr)
WO (1) WO2000026245A2 (fr)

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US6300096B1 (en) 1998-01-15 2001-10-09 Whitehead Institute For Biomedical Research Polynucleotides encoding fatty acid transport proteins
US6288213B1 (en) 1998-01-15 2001-09-11 Whitehead Institute For Biochemical Research Fatty acid transport proteins
US7033772B1 (en) 1998-01-15 2006-04-25 Millennium Pharmaceuticals, Inc. Methods of identifying inhibitors of fatty acid transport proteins (FATP)
US6657049B1 (en) 1998-01-15 2003-12-02 Whitehead Institute For Biomedical Research Fatty acid transport proteins
US6348321B1 (en) 1998-01-15 2002-02-19 Whitehead Institute For Biomedical Research Methods of identifying agents inhibiting fatty acid transport proteins
US6759238B1 (en) * 1999-03-31 2004-07-06 St. Jude Children's Research Hospital Multidrug resistance associated proteins and uses thereof
DE60042220D1 (de) 1999-09-21 2009-06-25 Chugai Pharmaceutical Co Ltd Verwendung vom transportergen oatp-c zur screening von testsubstanzen
JP2001211886A (ja) * 2000-02-07 2001-08-07 Japan Science & Technology Corp Ｌ−体及びｄ−体アミノ酸を輸送するナトリウム非依存性小型中性アミノ酸トランスポーター及びその遺伝子
US20020082405A1 (en) * 2000-03-06 2002-06-27 Gregory Donoho Novel human transporter proteins and polynucleotides encoding the same
EP1313854A2 (fr) * 2000-07-07 2003-05-28 Incyte Genomics, Inc. Transporteurs et canneaux d'ion
GB2390093A (en) * 2001-01-30 2003-12-31 Aeomica Inc Human sodium-hydrogen exchanger like protein 1
WO2002063002A2 (fr) * 2001-02-02 2002-08-15 Lexicon Genetics Incorporated Nouvelle proteine transporteuse humaine et polynucleotides la codant
FR2826373A1 (fr) * 2001-06-20 2002-12-27 Molecular Engines Laboratoires Sequences impliquees dans les phenomenes de suppression tumorale, reversion tumorale apoptose et/ou resistance aux virus et leur utilisation comme medicamments
US20060014940A1 (en) * 2002-02-28 2006-01-19 Mount David B Cloning and characterization of slc26a6, slc26a1, and slc26a2 anion exchangers
JP4445291B2 (ja) * 2003-03-10 2010-04-07 武田薬品工業株式会社 新規タンパク質およびそのｄｎａ
CA2600209A1 (fr) * 2005-03-11 2006-09-14 Sanofi-Aventis Utilisation de mgc4504
US7842291B1 (en) 2006-05-22 2010-11-30 Celera Corporation Methods and compositions for diagnosing and treating diseases

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WO2000001817A2 (fr) * 1998-07-06 2000-01-13 Schering Corporation Genes mammiferes ; transporteur du type prostaglandine de cellules dendritiques (dc-pgt), hdtea84, hsljd37r et rankl, chimiokine hcc5, proteines de desubiquitination 11 et 12 (dub11, dub12), md-1, md-2 et cycline e2, reactifs apparentes et procedes associes

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Title
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DATABASE GENEMBL 20 February 1998 (1998-02-20), HALLECK M.S. ET AL: "Homo sapiens putative ATPase mRNA, partial cds.", XP002132693 *
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SARDET C ET AL: "Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.", CELL, (1989 JAN 27) 56 (2) 271-80., XP000876824 *

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Publication number Publication date
EP1144443A3 (fr) 2001-12-05
AU1606800A (en) 2000-05-22
WO2000026245A2 (fr) 2000-05-11
CA2349818A1 (fr) 2000-05-11
EP1144443A2 (fr) 2001-10-17
JP2003521227A (ja) 2003-07-15

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