WO2000060082A3 - Proteines associees a une vesicule - Google Patents

Proteines associees a une vesicule Download PDF

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Publication number
WO2000060082A3
WO2000060082A3 PCT/US2000/009353 US0009353W WO0060082A3 WO 2000060082 A3 WO2000060082 A3 WO 2000060082A3 US 0009353 W US0009353 W US 0009353W WO 0060082 A3 WO0060082 A3 WO 0060082A3
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WO
WIPO (PCT)
Prior art keywords
veas
associated proteins
vesicle associated
provides
expression
Prior art date
Application number
PCT/US2000/009353
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English (en)
Other versions
WO2000060082A2 (fr
Inventor
Preeti Lal
Henry Yue
Jennifer L Hillman
Mariah R Baughn
Y Tom Tang
Dyung Aina M Lu
Yalda Azimzai
Original Assignee
Incyte Pharma Inc
Preeti Lal
Henry Yue
Jennifer L Hillman
Mariah R Baughn
Y Tom Tang
Dyung Aina M Lu
Yalda Azimzai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Preeti Lal, Henry Yue, Jennifer L Hillman, Mariah R Baughn, Y Tom Tang, Dyung Aina M Lu, Yalda Azimzai filed Critical Incyte Pharma Inc
Priority to AU42148/00A priority Critical patent/AU4214800A/en
Priority to JP2000609573A priority patent/JP2002540792A/ja
Priority to CA002365421A priority patent/CA2365421A1/fr
Priority to EP00921889A priority patent/EP1165789A2/fr
Publication of WO2000060082A2 publication Critical patent/WO2000060082A2/fr
Publication of WO2000060082A3 publication Critical patent/WO2000060082A3/fr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
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    • A61P13/00Drugs for disorders of the urinary system
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    • A61P17/00Drugs for dermatological disorders
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
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    • A61P19/00Drugs for skeletal disorders
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    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
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    • A61P25/00Drugs for disorders of the nervous system
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    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)

Abstract

L'invention concerne des protéines associées à des vésicules humaines et des polynucléotides qui identifient et codent ces protéines. L'invention traite également de vecteurs d'expression, de cellules hôtes, d'anticorps, d'agonistes et d'antagonistes. L'invention traite aussi de procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à l'expression des protéines associées à des vésicules humaines.
PCT/US2000/009353 1999-04-07 2000-04-06 Proteines associees a une vesicule WO2000060082A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU42148/00A AU4214800A (en) 1999-04-07 2000-04-06 Vesicle associated proteins
JP2000609573A JP2002540792A (ja) 1999-04-07 2000-04-06 小胞関連タンパク質
CA002365421A CA2365421A1 (fr) 1999-04-07 2000-04-06 Proteines associees a une vesicule
EP00921889A EP1165789A2 (fr) 1999-04-07 2000-04-06 Proteines associees a une vesicule

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12819399P 1999-04-07 1999-04-07
US60/128,193 1999-04-07
US14470199P 1999-07-20 1999-07-20
US60/144,701 1999-07-20

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/898,142 Division US20050074851A1 (en) 1999-04-07 2004-07-22 Vesicle associated proteins

Publications (2)

Publication Number Publication Date
WO2000060082A2 WO2000060082A2 (fr) 2000-10-12
WO2000060082A3 true WO2000060082A3 (fr) 2001-01-04

Family

ID=26826368

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/009353 WO2000060082A2 (fr) 1999-04-07 2000-04-06 Proteines associees a une vesicule

Country Status (5)

Country Link
EP (1) EP1165789A2 (fr)
JP (1) JP2002540792A (fr)
AU (1) AU4214800A (fr)
CA (1) CA2365421A1 (fr)
WO (1) WO2000060082A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403349B1 (en) * 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
WO2001029223A2 (fr) * 1999-10-20 2001-04-26 Zymogenetics, Inc. Proteine de membrane ztsl1 de type 1
WO2002016636A2 (fr) * 2000-08-24 2002-02-28 Evotec Neurosciences Gmbh Application diagnostique et therapeutique d'une proteine membranaire integrale associee aux caveolae a la maladie d'alzheimer et aux troubles neurodegeneratifs associes
WO2004044125A2 (fr) * 2002-05-15 2004-05-27 Incyte Corporation Proteines associees a la vesicule
EP2328611A4 (fr) * 2008-09-11 2011-10-12 Univ Ben Gurion Compositions et procédés destinés à traiter une infection par s. pneumoniae
TR201911667A2 (tr) 2019-08-01 2021-02-22 Univ Yeditepe Hücrelerde oluşan protein birikintilerinden kaynaklanan hastalıkların tedavisi için kullanılan bitki eksozomları.

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
E. C. DELL'ANGELICA ET AL: "AP-4, a novel protein complex related to Clathrin adaptators", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 274, no. 11, 12 March 1999 (1999-03-12), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD., US, pages 7278 - 7285, XP002141980, ISSN: 0021-9258 *
J. HIRST ET AL: "Characterization of a fourth adaptator-related protein Complex", MOLECULAR BIOLOGY OF THE CELL, vol. 10, no. 8, August 1999 (1999-08-01), pages 2787 - 2802, XP002141985 *
J. HIRST ET AL: "Homo sapiens adaptator-related protein complex AP-4 sigma subunit mRNA, complete cds.", EMBL DATABASE ENTRY AF155159, ACCESSION NUMBER AF155159, 12 July 1999 (1999-07-12), XP002141986 *
NCI-CGAP: "national cancer institute, cancer genome anatomy project (CGAP), tumor gene index", EMBL DATABASE ENTRY AI139578, ACCESSION NUMBER AI139578, 25 September 1998 (1998-09-25), XP002141981 *
SIMPSON FIONA ET AL: "Characterization of the adaptor-related protein complex, AP-3.", JOURNAL OF CELL BIOLOGY, vol. 137, no. 4, 1997, pages 835 - 845, XP002141983, ISSN: 0021-9525 *
UNPUBLISHED *
WANG XIAOLU ET AL: "Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2.", FEBS LETTERS, vol. 402, no. 1, 1997, pages 57 - 61, XP002141984, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
EP1165789A2 (fr) 2002-01-02
AU4214800A (en) 2000-10-23
JP2002540792A (ja) 2002-12-03
CA2365421A1 (fr) 2000-10-12
WO2000060082A2 (fr) 2000-10-12

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