WO1998047000A3 - Procede et reactif de mise en evidence d'un materiel biologique cible - Google Patents

Procede et reactif de mise en evidence d'un materiel biologique cible Download PDF

Info

Publication number
WO1998047000A3
WO1998047000A3 PCT/FR1998/000772 FR9800772W WO9847000A3 WO 1998047000 A3 WO1998047000 A3 WO 1998047000A3 FR 9800772 W FR9800772 W FR 9800772W WO 9847000 A3 WO9847000 A3 WO 9847000A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological material
target biological
bound
eliciting
reagent
Prior art date
Application number
PCT/FR1998/000772
Other languages
English (en)
Other versions
WO1998047000A2 (fr
Inventor
Abdelhamid Elaissari
David Duracher
Christian Pichot
Francois Mallet
Armelle Novelli-Rousseau
Original Assignee
Bio Merieux
Abdelhamid Elaissari
David Duracher
Christian Pichot
Francois Mallet
Novelli Rousseau Armelle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux, Abdelhamid Elaissari, David Duracher, Christian Pichot, Francois Mallet, Novelli Rousseau Armelle filed Critical Bio Merieux
Priority to AU74362/98A priority Critical patent/AU7436298A/en
Priority to EP98921550A priority patent/EP0975968A2/fr
Priority to JP54357298A priority patent/JP2001521625A/ja
Priority to CA002286382A priority patent/CA2286382A1/fr
Publication of WO1998047000A2 publication Critical patent/WO1998047000A2/fr
Publication of WO1998047000A3 publication Critical patent/WO1998047000A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un procédé de mise en évidence d'un matériel biologique cible contenu dans un échantillon, selon lequel on dispose d'une phase de capture, sous forme microparticulaire ou linéaire, et constituée par au moins un premier polymère particulaire ou linéaire, avec un caractère apparent hydrophile et des premiers groupements complexants, ces derniers étant liés par coordination à un premier métal de transition, qui est lui-même lié à une première entité biologique susceptible de reconnaître spécifiquement le matériel biologique cible; on met en contact ledit matériel biologique cible avec au moins la phase de capture; et on détecte le complexe phase de capture - matériel biologique cible, éventuellement avec une phase de détection, une phase de détection sous forme microparticulaire ou linéaire, et constituée par au moins un second polymère particulaire ou linéaire, avec un caractère apparent hydrophile et des seconds groupements complexants, ces derniers étant liés par coordination à un second métal de transition, qui est lui-même lié à une seconde entité biologique susceptible de reconnaître spécifiquement le matériel biologique cible, et un marqueur.
PCT/FR1998/000772 1997-04-16 1998-04-16 Procede et reactif de mise en evidence d'un materiel biologique cible WO1998047000A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU74362/98A AU7436298A (en) 1997-04-16 1998-04-16 Method for isolating a target biological material, capture phase, detection phase and reagent
EP98921550A EP0975968A2 (fr) 1997-04-16 1998-04-16 Procede et reactif de mise en evidence d'un materiel biologique cible
JP54357298A JP2001521625A (ja) 1997-04-16 1998-04-16 標的生物学的物質を単離するための方法、捕獲相、検出相、及び試薬
CA002286382A CA2286382A1 (fr) 1997-04-16 1998-04-16 Procede et reactif de mise en evidence d'un materiel biologique cible, phase de capture, phase de detection et reactif

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR97/04923 1997-04-16
FR9704923A FR2762394B1 (fr) 1997-04-16 1997-04-16 Compose ligand de coordination et utilisation pour fixer un materiel biologique

Publications (2)

Publication Number Publication Date
WO1998047000A2 WO1998047000A2 (fr) 1998-10-22
WO1998047000A3 true WO1998047000A3 (fr) 1999-02-11

Family

ID=9506151

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1998/000772 WO1998047000A2 (fr) 1997-04-16 1998-04-16 Procede et reactif de mise en evidence d'un materiel biologique cible

Country Status (7)

Country Link
US (1) US20020160526A1 (fr)
EP (1) EP0975968A2 (fr)
JP (1) JP2001521625A (fr)
AU (1) AU7436298A (fr)
CA (1) CA2286382A1 (fr)
FR (1) FR2762394B1 (fr)
WO (1) WO1998047000A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE44252E1 (en) 2002-01-10 2013-06-04 Cummins-Allison Corp. Coin redemption system

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2777355B1 (fr) 1998-04-10 2000-05-12 Bio Merieux Procede de fixation d'une molecule biologique sur la surface d'un support constitue de silice ou d'oxyde metallique
DE19927051C2 (de) * 1999-06-14 2002-11-07 November Ag Molekulare Medizin Verfahren und Vorrichtung zur Identifizierung einer Nukleotidsequenz
FR2804117B1 (fr) * 2000-01-21 2004-08-20 Bio Merieux Procede d'isolement de proteines et/ou d'acides nucleiques, complexes de particules et de proteines et/ou d'acides nucleiques, reactif et applications
ES2178961B1 (es) * 2001-03-06 2004-07-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Fabricacion de nanoparticulas a base del copolimero de metil vinil eter y anhidrido maleico para la administracion de farmacos de naturaleza hidrofilica, en particular de bases puricas y pirimidinicas.
FR2829580B1 (fr) 2001-09-07 2004-02-13 Bio Merieux Procede de lecture, de detection ou de quantification, hybrides ou complexes utilises dans ce procede et biopuce mettant en oeuvre ledit procede
AU2004251492B2 (en) * 2003-06-27 2011-03-17 Invitrogen Dynal As Conjugates of magnetic polymer particles and carboxymethylated aspartic acid
WO2005097844A1 (fr) * 2004-03-31 2005-10-20 Sumitomo Bakelite Co., Ltd. Particule polymere
US7316816B2 (en) * 2004-06-10 2008-01-08 Agency For Science Technology And Research Temperature and pH sensitive copolymers
JP5289707B2 (ja) * 2004-08-31 2013-09-11 住友ベークライト株式会社 オキシルアミノ基含有化合物
US20060240478A1 (en) 2005-02-23 2006-10-26 Fuji Photo Film Co., Ltd. Biosensor
JP4568175B2 (ja) * 2005-06-03 2010-10-27 富士フイルム株式会社 バイオセンサー及び生理活性物質の固定化方法
JP2006335912A (ja) * 2005-06-03 2006-12-14 Fujifilm Holdings Corp 生理活性物質固定化剤
US20080038190A1 (en) * 2006-08-11 2008-02-14 Simpson Thomas J Composition apparatus and method for use in imaging
EP2230312A1 (fr) * 2009-03-19 2010-09-22 Helmholtz-Zentrum für Infektionsforschung GmbH Composé de sonde pour détecter et isoler les enzymes et supports et procédés d'utilisation associés
CN105158465B (zh) * 2015-10-15 2016-08-24 河南中医学院第一附属医院 一种人类免疫缺陷病毒ⅰ型p24抗体检测elisa试剂盒

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880814A (en) * 1971-02-02 1975-04-29 Kiyoshi Mizutani Gel chromatography material and preparation thereof
FR2268818A1 (fr) * 1974-04-23 1975-11-21 Ceskoslovenska Akademie Ved
US4246350A (en) * 1979-03-01 1981-01-20 The Dow Chemical Company Protein immobilization on chelating resins
EP0156537A2 (fr) * 1984-03-02 1985-10-02 Board Of Regents University Of Texas System Fluide magnétique biologique
US4784912A (en) * 1985-03-18 1988-11-15 Eastman Kodak Company Latex particles incorporating stabilized fluorescent rare earth labels
EP0310872A1 (fr) * 1987-10-07 1989-04-12 Hygeia Sciences, Inc. Technique d'essai immunologique par capture de sol métallique, nécessaire à utiliser dans celle-ci et composé contenant du métal capté
US5132243A (en) * 1986-09-09 1992-07-21 Mitsui Petrochemical Industries, Ltd. Carrier latex for use as diagnostic reagent
EP0516198A2 (fr) * 1985-10-04 1992-12-02 Nycomed Imaging As Particules magnétiques-polymères
US5244816A (en) * 1989-10-11 1993-09-14 Akzo N.V. Method for purifying chelator conjugated compounds
EP0659779A2 (fr) * 1993-12-22 1995-06-28 Fujimori Kogyo Co., Ltd. Microsphères et procédé de leur préparation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0056664B1 (fr) * 1978-09-21 1986-11-12 EASTMAN KODAK COMPANY (a New Jersey corporation) Polymères d'addition et leurs complexes métalliques
JPS6390521A (ja) * 1986-10-04 1988-04-21 Nippon Zeon Co Ltd 両性重合体粒子の製造方法
JP2701294B2 (ja) * 1987-03-14 1998-01-21 日本油脂株式会社 アルケニルエーテル−無水マレイン酸共重合体
US5180822A (en) * 1988-09-21 1993-01-19 Reilly Industries, Inc. Highly selective chelating resins and monomers for their preparation
US5455359B1 (en) * 1993-10-01 1998-05-05 Res Corp Technologies Inc Metal ion binding monomer and polymer

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880814A (en) * 1971-02-02 1975-04-29 Kiyoshi Mizutani Gel chromatography material and preparation thereof
FR2268818A1 (fr) * 1974-04-23 1975-11-21 Ceskoslovenska Akademie Ved
US4246350A (en) * 1979-03-01 1981-01-20 The Dow Chemical Company Protein immobilization on chelating resins
EP0156537A2 (fr) * 1984-03-02 1985-10-02 Board Of Regents University Of Texas System Fluide magnétique biologique
US4784912A (en) * 1985-03-18 1988-11-15 Eastman Kodak Company Latex particles incorporating stabilized fluorescent rare earth labels
EP0516198A2 (fr) * 1985-10-04 1992-12-02 Nycomed Imaging As Particules magnétiques-polymères
US5132243A (en) * 1986-09-09 1992-07-21 Mitsui Petrochemical Industries, Ltd. Carrier latex for use as diagnostic reagent
EP0310872A1 (fr) * 1987-10-07 1989-04-12 Hygeia Sciences, Inc. Technique d'essai immunologique par capture de sol métallique, nécessaire à utiliser dans celle-ci et composé contenant du métal capté
US5244816A (en) * 1989-10-11 1993-09-14 Akzo N.V. Method for purifying chelator conjugated compounds
EP0659779A2 (fr) * 1993-12-22 1995-06-28 Fujimori Kogyo Co., Ltd. Microsphères et procédé de leur préparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KEMPE M ET AL: "An Approach to Surface Imprinting Using The Enzyme Ribonuclease A", JOURNAL OF MOLECULAR RECOGNITION, vol. 8, 1995, pages 35, XP002050518 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE44252E1 (en) 2002-01-10 2013-06-04 Cummins-Allison Corp. Coin redemption system

Also Published As

Publication number Publication date
US20020160526A1 (en) 2002-10-31
AU7436298A (en) 1998-11-11
WO1998047000A2 (fr) 1998-10-22
CA2286382A1 (fr) 1998-10-22
FR2762394B1 (fr) 1999-05-28
FR2762394A1 (fr) 1998-10-23
JP2001521625A (ja) 2001-11-06
EP0975968A2 (fr) 2000-02-02

Similar Documents

Publication Publication Date Title
WO1998047000A3 (fr) Procede et reactif de mise en evidence d'un materiel biologique cible
WO2000012123A3 (fr) Procede et dispositif de mesure pour la determination d'une pluralite d'analytes dans un echantillon
EP0853129A3 (fr) Appareils et procédés de détection d'analytes d'acides nucléiques dans des échantillons
AU637489B2 (en) Conjugate recovery binding assays and devices
WO1999016781A3 (fr) Procede de preparation d'echantillons automatisable, a usage universel
WO2001050129A3 (fr) Compensation des signaux non specifiques dans des analyses immunologiques quantitatives
WO2003023057A3 (fr) Procede et kit de diagnostic destines a la selection et/ou detection qualitative et/ou quantitative de cellules
EP1156329A3 (fr) Essais à modification moléculaire
CA2252912A1 (fr) Methode d'essai, trousse et dispositif d'analyse
EP0837141A3 (fr) Procédé pour détecter un acide nucléique ciblé, procédé pour sa détermination quantitative et composés pyryliums pour l'analyse en chimioluminescence
CA2331688A1 (fr) Detection d'une cible dans un echantillon
CA2188752A1 (fr) Dosage immunologique de l'homocysteine
WO2003073817A3 (fr) Detection rapide et sensible de cellules et de virus
WO2003031977A3 (fr) Dosage par liaison utilisant un champ magnetique
WO2004011607A3 (fr) Reactif et technique de determination d'une substance utilisant un immunoregroupeur
ATE112059T1 (de) Verfahren zur bestimmung eines analyten.
CA2420011A1 (fr) Procede rapide de dosage immunoenzymatique facilite par l'utilisation de micro-ondes
WO2002004670A3 (fr) Format de capture ameliore pour des tests sur bandelettes reactives
EP1293780A3 (fr) Méthode d'analyse à liaison spécifique
DE69811614T2 (de) Verfahren zur detektierung eines biologischen materials, eingangphase, detektionsphase und diese enthaltende reagenz
EP0346119A3 (fr) Essai anti-FC pour détecter des anticorps
WO1996019731A3 (fr) Procede de detection, par mesure de temps differentielle, de plusieurs analytes dans un echantillon test
WO2003019194A3 (fr) Essai de deplacement pour la detection d'evenements d'association ligat-ligand
EP0387027A3 (fr) Méthodes et réactifs pour le diagnostic de l'endométriose
CA2213083A1 (fr) Detection de la production d'anticorps

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1998921550

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2286382

Country of ref document: CA

Ref country code: CA

Ref document number: 2286382

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 1998 543572

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 09403085

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 1998921550

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1998921550

Country of ref document: EP