WO1996022529A1 - A method of generating a plurality of chemical compounds in a spatially arranged array - Google Patents

A method of generating a plurality of chemical compounds in a spatially arranged array Download PDF

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Publication number
WO1996022529A1
WO1996022529A1 PCT/US1996/001005 US9601005W WO9622529A1 WO 1996022529 A1 WO1996022529 A1 WO 1996022529A1 US 9601005 W US9601005 W US 9601005W WO 9622529 A1 WO9622529 A1 WO 9622529A1
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WO
WIPO (PCT)
Prior art keywords
array
compounds
reaction site
chemical
molecular
Prior art date
Application number
PCT/US1996/001005
Other languages
English (en)
French (fr)
Inventor
Robert A. Zambias
David A. Bolten
Joseph C. Hogan
Paul Furth
David S. Casebier
Cheng Tu
Original Assignee
Arqule, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule, Inc. filed Critical Arqule, Inc.
Priority to JP8522446A priority Critical patent/JPH11503720A/ja
Priority to AU47059/96A priority patent/AU719584C/en
Priority to NZ301594A priority patent/NZ301594A/xx
Priority to PL96327437A priority patent/PL327437A1/xx
Priority to EP96902775A priority patent/EP0804726A4/en
Publication of WO1996022529A1 publication Critical patent/WO1996022529A1/en
Priority to NO973335A priority patent/NO973335L/no

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y10S977/774—Exhibiting three-dimensional carrier confinement, e.g. quantum dots
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/778—Nanostructure within specified host or matrix material, e.g. nanocomposite films
    • Y10S977/779—Possessing nanosized particles, powders, flakes, or clusters other than simple atomic impurity doping
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/789—Of specified organic or carbon-based composition in array format
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/789—Of specified organic or carbon-based composition in array format
    • Y10S977/79—Of specified organic or carbon-based composition in array format with heterogeneous nanostructures
    • Y10S977/791—Molecular array

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Structural Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Aerodynamic Tests, Hydrodynamic Tests, Wind Tunnels, And Water Tanks (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/US1996/001005 1995-01-20 1996-01-19 A method of generating a plurality of chemical compounds in a spatially arranged array WO1996022529A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP8522446A JPH11503720A (ja) 1995-01-20 1996-01-19 空間的に配置されたアレイ中で複数の化学物質を製造する方法
AU47059/96A AU719584C (en) 1995-01-20 1996-01-19 A method of generating a plurality of chemical compounds in a spatially arranged array
NZ301594A NZ301594A (en) 1995-01-20 1996-01-19 Generating a plurality of chemical compounds in a spatially arranged array whereby the scaffold is an aminimide, imidazolone, sulphonylaminimide, and/or phophonylaminimide
PL96327437A PL327437A1 (en) 1995-01-20 1996-01-19 Method of obtaining a plurality of chemical compounds in a three-dimensionally ordered table
EP96902775A EP0804726A4 (en) 1995-01-20 1996-01-19 PROCESS FOR PRODUCING DIFFERENT CHEMICAL COMPOUNDS CONSTITUTING A SPATIAL NETWORK
NO973335A NO973335L (no) 1995-01-20 1997-07-18 Fremgangsmåte for fremstilling av et flertall kjemiske stoffer i en tabelloppstilling

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US375,838 1995-01-20
US08/375,838 US5712171A (en) 1995-01-20 1995-01-20 Method of generating a plurality of chemical compounds in a spatially arranged array

Publications (1)

Publication Number Publication Date
WO1996022529A1 true WO1996022529A1 (en) 1996-07-25

Family

ID=23482579

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/001005 WO1996022529A1 (en) 1995-01-20 1996-01-19 A method of generating a plurality of chemical compounds in a spatially arranged array

Country Status (13)

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US (4) US5712171A (US06878557-20050412-C00013.png)
EP (1) EP0804726A4 (US06878557-20050412-C00013.png)
JP (1) JPH11503720A (US06878557-20050412-C00013.png)
KR (1) KR100414424B1 (US06878557-20050412-C00013.png)
AU (1) AU719584C (US06878557-20050412-C00013.png)
CA (1) CA2210949A1 (US06878557-20050412-C00013.png)
CZ (1) CZ232297A3 (US06878557-20050412-C00013.png)
HU (1) HUP9802293A3 (US06878557-20050412-C00013.png)
IL (1) IL116838A0 (US06878557-20050412-C00013.png)
NO (1) NO973335L (US06878557-20050412-C00013.png)
NZ (1) NZ301594A (US06878557-20050412-C00013.png)
PL (1) PL327437A1 (US06878557-20050412-C00013.png)
WO (1) WO1996022529A1 (US06878557-20050412-C00013.png)

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US8697875B2 (en) 2008-12-23 2014-04-15 The Trustees Of Columbia University In The City Of New York Phosphodiesterase inhibitors and uses thereof
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EP0804726A4 (en) 2004-07-07
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HUP9802293A2 (hu) 1999-02-01
US5712171A (en) 1998-01-27
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PL327437A1 (en) 1998-12-07
HUP9802293A3 (en) 1999-03-29
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NO973335L (no) 1997-08-21
AU4705996A (en) 1996-08-07
CA2210949A1 (en) 1996-07-25
IL116838A0 (en) 1996-07-23
JPH11503720A (ja) 1999-03-30
AU719584B2 (en) 2000-05-11
NO973335D0 (no) 1997-07-18
KR100414424B1 (ko) 2004-07-07
AU719584C (en) 2001-07-26
EP0804726A1 (en) 1997-11-05
US5736412A (en) 1998-04-07

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