WO1996011692A1 - Utilisation d'anthocyanidine et de ses derives dans le traitement des infections retrovirales - Google Patents

Utilisation d'anthocyanidine et de ses derives dans le traitement des infections retrovirales Download PDF

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Publication number
WO1996011692A1
WO1996011692A1 PCT/NO1995/000185 NO9500185W WO9611692A1 WO 1996011692 A1 WO1996011692 A1 WO 1996011692A1 NO 9500185 W NO9500185 W NO 9500185W WO 9611692 A1 WO9611692 A1 WO 9611692A1
Authority
WO
WIPO (PCT)
Prior art keywords
glycosyl
group
groups
anthocyanidin
acyl
Prior art date
Application number
PCT/NO1995/000185
Other languages
English (en)
Other versions
WO1996011692A9 (fr
Inventor
Øyvind M. ANDERSEN
Dag E. Helland
Original Assignee
Unifob Stiftelsen Universitetsforskning Bergen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unifob Stiftelsen Universitetsforskning Bergen filed Critical Unifob Stiftelsen Universitetsforskning Bergen
Priority to AU37569/95A priority Critical patent/AU3756995A/en
Priority to EP95935625A priority patent/EP0785790A1/fr
Publication of WO1996011692A1 publication Critical patent/WO1996011692A1/fr
Publication of WO1996011692A9 publication Critical patent/WO1996011692A9/fr
Priority to NO971573A priority patent/NO971573L/no
Priority to FI971459A priority patent/FI971459A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin

Abstract

Utilisation d'une anthocyanidine ou d'un dérivé d'anthocyanidine répondant à la formule générale (I), dans laquelle R1, R2, R3 et R6 indépendamment les uns des autres, représentent H, OH, alcoxy, un groupe -O-glycosyle, un groupe -O-glycosyle substitué par un ou plusieurs groupes acyles, ou une fraction -O-glycosyle comportant au moins deux groupes glycosyles et au moins un groupe acyle disposés de telle sorte qu'au moins un groupe acyle se situe entre deux groupes glycosyles; R4 représente OH, alcoxy, un groupe -O-glycosyle substitué par un ou plusieurs groupes acyles, ou une fraction -O-glycosyle comportant au moins deux groupes glycosyles et au moins un groupe acyle disposés de telle sorte qu'au moins un groupe acyle se situe entre deux groupes glycosyles; R5 représente H ou OH; et Y représente un contre-ion ou un sel, promédicament ou complexe de celui-ci; dans la préparation d'une composition pharmaceutique destinée à la prophylaxie et/ou au traitement des infections rétrovirales chez les mammifères. On a également prévu de nouveaux dérivés d'anthocyanidine répondant à la formule générale (I), et des procédés de préparation de ces composés et de nouvelles compositions pharmaceutiques.
PCT/NO1995/000185 1994-10-13 1995-10-10 Utilisation d'anthocyanidine et de ses derives dans le traitement des infections retrovirales WO1996011692A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU37569/95A AU3756995A (en) 1994-10-13 1995-10-10 Use of anthocyanidin and derivatives for treatment of retroviral infections
EP95935625A EP0785790A1 (fr) 1994-10-13 1995-10-10 Utilisation d'anthocyanidine et de ses derives dans le traitement des infections retrovirales
NO971573A NO971573L (no) 1994-10-13 1997-04-07 Anvendelse av antocyaner samt derivater derav for behandling av retrovirale infeksjoner
FI971459A FI971459A (fi) 1994-10-13 1997-04-08 Antosyanidiinin ja sen johdannaisten käyttö retroviraalisten infektioiden hoitoon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO943860 1994-10-13
NO943860A NO943860D0 (no) 1994-10-13 1994-10-13 En kjemisk forbindelse og et preparat til bruk som terapeutikum

Publications (2)

Publication Number Publication Date
WO1996011692A1 true WO1996011692A1 (fr) 1996-04-25
WO1996011692A9 WO1996011692A9 (fr) 1996-06-20

Family

ID=19897498

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NO1995/000185 WO1996011692A1 (fr) 1994-10-13 1995-10-10 Utilisation d'anthocyanidine et de ses derives dans le traitement des infections retrovirales

Country Status (6)

Country Link
EP (1) EP0785790A1 (fr)
AU (1) AU3756995A (fr)
CA (1) CA2202467A1 (fr)
FI (1) FI971459A (fr)
NO (1) NO943860D0 (fr)
WO (1) WO1996011692A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997041137A1 (fr) * 1996-04-17 1997-11-06 Unifob Utilisation d'anthocyanidine et de derives d'anthocyanidine
EP1882473A1 (fr) * 2006-07-28 2008-01-30 Indena S.P.A. Utilistation d'anthocyanosides pour la préparation de formulations pour le traitement de la mucosite induite par les médicaments antitumoraux
AU2005301315B2 (en) * 2004-07-29 2008-04-10 Michigan State University Insulin secretion by anthocyanins and anthocyanidins

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0312222A1 (fr) * 1987-10-14 1989-04-19 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Traitement de maladies virales
JPH03209320A (ja) * 1990-01-09 1991-09-12 Toray Ind Inc 抗レトロウイルス薬
JPH03209321A (ja) * 1990-01-09 1991-09-12 Toray Ind Inc 抗レトロウイルス薬

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0312222A1 (fr) * 1987-10-14 1989-04-19 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Traitement de maladies virales
JPH03209320A (ja) * 1990-01-09 1991-09-12 Toray Ind Inc 抗レトロウイルス薬
JPH03209321A (ja) * 1990-01-09 1991-09-12 Toray Ind Inc 抗レトロウイルス薬

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANDERSEN, OEYVIND M. ET AL: "Structure of petanin, an acylated anthocyanin isolated from Solanum tuberosum, using homo- and hetero-nuclear two-dimensional nuclear magnetic resonance techniques", PHYTOCHEM. ANAL., 1991, 230-6 *
DATABASE WPI Section Ch Week 9143, Derwent World Patents Index; Class B02, AN 91-314166 *
DATABASE WPI Section Ch Week 9143, Derwent World Patents Index; Class B02, AN 91-314167 *
VERZAR-PETRI, G. ET AL: "Polyphenols of Cotinus Coggygria and their therapeutical value", FLAVONOIDS AND BIOFLAVONOIDS, vol. 23, pages 241 - 250 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997041137A1 (fr) * 1996-04-17 1997-11-06 Unifob Utilisation d'anthocyanidine et de derives d'anthocyanidine
AU2005301315B2 (en) * 2004-07-29 2008-04-10 Michigan State University Insulin secretion by anthocyanins and anthocyanidins
EP1882473A1 (fr) * 2006-07-28 2008-01-30 Indena S.P.A. Utilistation d'anthocyanosides pour la préparation de formulations pour le traitement de la mucosite induite par les médicaments antitumoraux
WO2008012666A3 (fr) * 2006-07-28 2008-09-04 Indena Spa Procédés de traitement et de prévention d'une mucite
EP2520295A1 (fr) * 2006-07-28 2012-11-07 INDENA S.p.A. Procédés pour prévenir et traiter la mucosite
US9730952B2 (en) 2006-07-28 2017-08-15 Indena S.P.A. Methods for treating and preventing mucositis

Also Published As

Publication number Publication date
NO943860D0 (no) 1994-10-13
CA2202467A1 (fr) 1996-04-25
AU3756995A (en) 1996-05-06
FI971459A (fi) 1997-06-05
EP0785790A1 (fr) 1997-07-30
FI971459A0 (fi) 1997-04-08

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