WO1987006008A3 - Automated multi-purposse analytical chemistry processing center and laboratory work station - Google Patents

Automated multi-purposse analytical chemistry processing center and laboratory work station Download PDF

Info

Publication number
WO1987006008A3
WO1987006008A3 PCT/US1987/000501 US8700501W WO8706008A3 WO 1987006008 A3 WO1987006008 A3 WO 1987006008A3 US 8700501 W US8700501 W US 8700501W WO 8706008 A3 WO8706008 A3 WO 8706008A3
Authority
WO
WIPO (PCT)
Prior art keywords
work station
measurements
analytical chemistry
processing center
modules
Prior art date
Application number
PCT/US1987/000501
Other languages
French (fr)
Other versions
WO1987006008A2 (en
Inventor
Dale R Pfost
Torleif O Bjornson
Robert M Coppock
Carl Kowalski
Samuel A Marquiss
Donald S Murray
R Fred Pfost
Brian Sanford
Katherine L Puckett
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Publication of WO1987006008A2 publication Critical patent/WO1987006008A2/en
Publication of WO1987006008A3 publication Critical patent/WO1987006008A3/en
Priority to FI875113A priority Critical patent/FI875113A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/103—General features of the devices using disposable tips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1058—General features of the devices using the transfer device for another function for mixing
    • G01N2035/106—General features of the devices using the transfer device for another function for mixing by sucking and blowing

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Treatment And Welfare Office Work (AREA)

Abstract

An automated multi-purpose analytical chemistry processing center and laboratory work station having a movable table (28) for supporting microtiter plates (27) and other fluid receptacles, a movable arm (44), and a modular mobile pod (42) affixed for reciprocal movement along the arm (44). The workstation combines into a single programmable system the capabilities for automation of a wide range of bioanalytical procedures including, not only sample pipetting, serial dilution, reagent additions, mixing, reaction timing and similar known manual procedures, but also programmable spectrophotometric measurements and other physical parameters, further processing based on these measurements and automatic data recording. The work station is adapted to transfer, dispense, and aspirate liquid from one location to another automatically in accordance with user programmed instructions. The work station is capable of measuring physical characteristics of selected samples and performing experimental assays in a closed loop manner in accordance with those measurements. Fluid is dispensed and aspirated using an interchangeable modules (52) having one or a selected plurality of nozzles (54). Affixed to the modules nozzles are disposable pipettor tips (56), which are automatically picked up by the pod (42) and ejected by a tip ejector mechanism (58) at the control of the user. Additional modules may be used to perform Measurement Functions. The work station is designed for interactive connection with a remote computer.
PCT/US1987/000501 1986-03-26 1987-03-05 Automated multi-purposse analytical chemistry processing center and laboratory work station WO1987006008A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI875113A FI875113A0 (en) 1986-03-26 1987-11-19 AUTOMATISK UNIVERSAL BEHANDLINGSCENTRAL OCH LABORATORIEARBETSSTATION FOER ANALYTISK KEMI.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84437486A 1986-03-26 1986-03-26
US844,374 1986-03-26

Publications (2)

Publication Number Publication Date
WO1987006008A2 WO1987006008A2 (en) 1987-10-08
WO1987006008A3 true WO1987006008A3 (en) 1987-11-05

Family

ID=25292559

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1987/000501 WO1987006008A2 (en) 1986-03-26 1987-03-05 Automated multi-purposse analytical chemistry processing center and laboratory work station

Country Status (4)

Country Link
EP (1) EP0261202A1 (en)
JP (3) JPS63502931A (en)
FI (1) FI875113A0 (en)
WO (1) WO1987006008A2 (en)

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US5116122A (en) * 1991-03-14 1992-05-26 Shimadzu Corporation Spectrophotometer
US5696887A (en) * 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
US5345395A (en) * 1991-10-31 1994-09-06 Baxter Diagnostics Inc. Specimen processing and analyzing systems and methods using photometry
US5670113A (en) * 1991-12-20 1997-09-23 Sibia Neurosciences, Inc. Automated analysis equipment and assay method for detecting cell surface protein and/or cytoplasmic receptor function using same
DE59308553D1 (en) * 1992-02-13 1998-06-25 Hoffmann La Roche Automatic pipetting device
GB9314991D0 (en) * 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
IT1265504B1 (en) * 1993-09-06 1996-11-22 Viptronic Srl EQUIPMENT AND SYSTEM FOR CARRYING OUT DENSITOMETRIC AND/OR COLORIMETRIC DETECTIONS AND CONTROLS.
US6800452B1 (en) * 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
IT1278570B1 (en) * 1994-09-08 1997-11-24 Seac Srl AUTOMATIC EQUIPMENT FOR IMMUNOLOGICAL ANALYSIS
EP0784796A4 (en) * 1994-10-07 1998-11-11 Flinders Technologies Pty Ltd Apparatus and method for storage, purification or reaction and processing of a biopolymer
JP3533502B2 (en) * 1994-10-14 2004-05-31 株式会社日立製作所 Automatic chemical analyzer
EP0810428B1 (en) * 1996-05-29 2004-04-28 Walter Dr. Schubert Automated device and method for measuring and identifying molecules or fragments thereof
US5968731A (en) * 1996-12-10 1999-10-19 The Regents Of The University Of California Apparatus for automated testing of biological specimens
US5841975A (en) * 1996-12-10 1998-11-24 The Regents Of The University Of California Method and apparatus for globally-accessible automated testing
US5925514A (en) * 1996-12-10 1999-07-20 The Regents Of The University Of California Apparatus for testing for infection by a retrovirus
AU6134398A (en) * 1997-01-22 1998-08-07 Biacore Ab Pipette and carrier assembly for a sensor
DE19746455C1 (en) 1997-10-21 1999-05-27 Jenoptik Jena Gmbh Automatic pipetting and handling device for microtitration plates with permeable bottoms
US7199809B1 (en) 1998-10-19 2007-04-03 Symyx Technologies, Inc. Graphic design of combinatorial material libraries
DE19850841A1 (en) * 1998-11-04 2000-05-25 Eppendorf Geraetebau Netheler Method for operating an electronic dosing system and dosing system for carrying out the method
GB2351556B (en) * 1999-06-26 2004-06-30 Cambridge Imaging Ltd Improved assay analysis
JP2002022752A (en) * 2000-07-13 2002-01-23 Suzuki Motor Corp Specimen testing device
JP2002203042A (en) * 2000-12-28 2002-07-19 Oriental Yeast Co Ltd Preclinical test support system
NZ510255A (en) * 2001-02-28 2003-01-31 Intellitech Automation Ltd sample preparation apparatus, typically for milk sampling, with double pivoting robotic arm
JP2002269180A (en) * 2001-03-07 2002-09-20 Japan Tissue Engineering:Kk Culture managing device and program therefor
US7250303B2 (en) 2001-07-20 2007-07-31 Ortho-Clinical Diagnostics, Inc. Chemistry system for a clinical analyzer
DE10143991A1 (en) 2001-09-07 2003-04-10 Bruker Axs Gmbh X-ray analyzer
JP2003279585A (en) * 2003-03-10 2003-10-02 Hitachi Ltd Automatic chemical analysis apparatus
CA2512353A1 (en) * 2004-07-16 2006-01-16 Stemcell Technologies Inc. Automated pipette machine
US8366997B2 (en) 2009-02-10 2013-02-05 Shoto Technologies Llc Modular laboratory automation system
CN101881706B (en) * 2010-07-05 2014-04-02 深圳迈瑞生物医疗电子股份有限公司 Sampling device and method
EP3392647A4 (en) * 2015-12-15 2019-05-01 Universal Bio Research Co., Ltd. Absorbance measuring apparatus and method
US11331660B2 (en) * 2019-01-04 2022-05-17 Funai Electric Co. Ltd. Digital dispense system
CN109775373A (en) * 2019-03-18 2019-05-21 北京爱博生生物技术有限公司 A kind of full-automatic microwell plate board-washing work station of goods yard formula
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EP0138205A1 (en) * 1983-10-14 1985-04-24 Cetus Corporation Bi-directional liquid sample handling system

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Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
US4090791A (en) * 1975-10-29 1978-05-23 Battelle Memorial Institute Device for cyclically repeating a series of colorimetric analysis on each of a succession of samples
GB2089034A (en) * 1980-12-10 1982-06-16 Becton Dickinson Co Analysing and evaluating tests in a plurality of wells
US4495149A (en) * 1981-09-18 1985-01-22 Toa Medical Electronic Co., Ltd. Optical-type automatic analyzing and measuring apparatus
EP0136002A2 (en) * 1983-08-30 1985-04-03 Labsystems Oy Measuring apparatus provided with liquid dispenser
EP0138205A1 (en) * 1983-10-14 1985-04-24 Cetus Corporation Bi-directional liquid sample handling system

Also Published As

Publication number Publication date
WO1987006008A2 (en) 1987-10-08
EP0261202A1 (en) 1988-03-30
FI875113A (en) 1987-11-19
JPS63502931A (en) 1988-10-27
JPH0882630A (en) 1996-03-26
JPH0854401A (en) 1996-02-27
FI875113A0 (en) 1987-11-19

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