UY33568A - Compuestos que interactuan con proteina reguladora de glucocinasa para el tratamiento de diabetes. - Google Patents

Compuestos que interactuan con proteina reguladora de glucocinasa para el tratamiento de diabetes.

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Publication number
UY33568A
UY33568A UY0001033568A UY33568A UY33568A UY 33568 A UY33568 A UY 33568A UY 0001033568 A UY0001033568 A UY 0001033568A UY 33568 A UY33568 A UY 33568A UY 33568 A UY33568 A UY 33568A
Authority
UY
Uruguay
Prior art keywords
compounds
diabetes
interact
glucocinase
treatment
Prior art date
Application number
UY0001033568A
Other languages
English (en)
Spanish (es)
Inventor
Bo Yunxin
Liu Longbin
Nishimura Nobuko
Mark H Norman
Nuria A Tamayo
Ashton Kate
Michael David Bartberger
Marian C Bryan
Croghan Michael
Clarence Henderson Hale
Roxanne Kay Kunz
Lewis Dale Pennington
Steve Fong Poon
Markian Myroslaw Stec
David Joseph St Jean Jr
Kevin Chao Yang
Christopher Harold Fotsch
Christopher Michael Tegley
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of UY33568A publication Critical patent/UY33568A/es

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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
UY0001033568A 2010-08-23 2011-08-23 Compuestos que interactuan con proteina reguladora de glucocinasa para el tratamiento de diabetes. UY33568A (es)

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WO2014035872A1 (en) * 2012-08-27 2014-03-06 Amgen Inc. Tricyclic alkynes that interact with glucokinase regulatory protein
JP6102637B2 (ja) * 2013-08-22 2017-03-29 Jsr株式会社 芳香族ジハライド化合物、重合体、重合体組成物及び成形体
CN108912020B (zh) * 2018-06-05 2021-05-28 上海博志研新药物技术有限公司 奥当卡替及其中间体的制备方法
US20240124400A1 (en) * 2019-10-11 2024-04-18 Duke University Lpxh targeting compounds, compositions thereof, and methods of making and using the same
CN114349711B (zh) * 2022-02-28 2023-08-15 四川依维欣医药科技有限公司 一种（R）-1-Boc-3-羟甲基哌嗪的合成方法

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US8431563B2 (en) 2013-04-30
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EP2609081A1 (en) 2013-07-03

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