UY33211A - - Google Patents

Info

Publication number
UY33211A
UY33211A UY33211A UY33211A UY33211A UY 33211 A UY33211 A UY 33211A UY 33211 A UY33211 A UY 33211A UY 33211 A UY33211 A UY 33211A UY 33211 A UY33211 A UY 33211A
Authority
UY
Uruguay
Application number
UY33211A
Inventor
Jean-Louis Peglion
Pascal Caignard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of UY33211A publication Critical patent/UY33211A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/74Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
UY33211A 2010-02-17 2011-01-31 UY33211A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1000657A FR2956401B1 (fr) 2010-02-17 2010-02-17 Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable

Publications (1)

Publication Number Publication Date
UY33211A true UY33211A (es) 2011-07-29

Family

ID=42133409

Family Applications (1)

Application Number Title Priority Date Filing Date
UY33211A UY33211A (es) 2010-02-17 2011-01-31

Country Status (36)

Country Link
US (1) US8278440B2 (es)
EP (1) EP2364972B1 (es)
JP (1) JP5306387B2 (es)
KR (1) KR101310683B1 (es)
CN (3) CN103265491B (es)
AR (1) AR080178A1 (es)
AU (1) AU2011200403B2 (es)
BR (1) BRPI1100169A2 (es)
CA (1) CA2731315C (es)
CL (1) CL2011000297A1 (es)
CY (1) CY1113338T1 (es)
DK (1) DK2364972T3 (es)
EA (1) EA019373B1 (es)
ES (1) ES2396042T3 (es)
FR (1) FR2956401B1 (es)
GE (1) GEP20135737B (es)
HK (3) HK1162021A1 (es)
HR (1) HRP20120955T1 (es)
JO (1) JO2854B1 (es)
MA (1) MA32681B1 (es)
ME (1) ME01464B (es)
MX (1) MX2011001465A (es)
MY (1) MY147697A (es)
NZ (1) NZ590883A (es)
PE (1) PE20120576A1 (es)
PL (1) PL2364972T3 (es)
PT (1) PT2364972E (es)
RS (1) RS52529B (es)
SA (1) SA111320199B1 (es)
SG (1) SG173961A1 (es)
SI (1) SI2364972T1 (es)
TW (1) TWI395738B (es)
UA (1) UA106208C2 (es)
UY (1) UY33211A (es)
WO (1) WO2011101558A1 (es)
ZA (1) ZA201100964B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2950343B1 (fr) * 2009-09-18 2011-11-18 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
CN102566619B (zh) * 2012-02-07 2013-12-25 宁波市镇海华泰电器厂 噪声式水温控制装置
FR2988720B1 (fr) * 2012-03-27 2014-03-14 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
CN103848789B (zh) * 2012-11-29 2016-05-18 江苏恒瑞医药股份有限公司 一种伊伐布雷定的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
FR2681862B1 (fr) * 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
WO2002051232A2 (en) 2000-12-27 2002-07-04 Actelion Pharmaceuticals Ltd. Novel benzazepines and related heterocyclic derivatives
US7008958B2 (en) * 2002-05-21 2006-03-07 Bristol-Myers Squibb Company 2-substituted 5-oxazolyl indole compounds useful as IMPDH inhibitors and pharmaceutical compositions comprising same
FR2868777B1 (fr) * 2004-04-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2868776B1 (fr) * 2004-04-13 2008-04-18 Servier Lab Nouveau procede de synthese de derives de la 1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2868775B1 (fr) * 2004-04-13 2008-04-11 Servier Lab Nouveau procede de synthese de derives de la 1,3,4,5- tetrahydro-2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
TW200817334A (en) * 2005-02-07 2008-04-16 Servier Lab New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
ATE544754T1 (de) * 2006-11-30 2012-02-15 Cadila Healthcare Ltd Verfahren zur herstellung von ivabradinhydrochlorid
CN101284813B (zh) * 2007-04-12 2012-08-15 上海优拓医药科技有限公司 伊伐布雷定的制备方法
EP2471780B1 (en) * 2007-05-30 2014-11-26 Ind-Swift Laboratories Limited Crystalline Ivabradine Oxalate Salts and Polymorphs Thereof
CN101544605A (zh) * 2008-03-24 2009-09-30 北京深蓝海生物医药科技有限公司 伊伐布雷定及其药学上可接受的加成盐的制备方法
FR2932800B1 (fr) 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
ES2402765T3 (es) 2008-12-22 2013-05-08 Krka, D.D., Novo Mesto Procedimiento de preparación de ivabradina

Also Published As

Publication number Publication date
AR080178A1 (es) 2012-03-21
CN103265491A (zh) 2013-08-28
MX2011001465A (es) 2011-08-30
EP2364972A1 (fr) 2011-09-14
US20110201805A1 (en) 2011-08-18
ME01464B (me) 2014-04-20
CL2011000297A1 (es) 2012-02-17
JP5306387B2 (ja) 2013-10-02
NZ590883A (en) 2012-01-12
EA019373B1 (ru) 2014-03-31
KR101310683B1 (ko) 2013-09-24
CN102161642B (zh) 2014-03-19
BRPI1100169A2 (pt) 2012-07-31
US8278440B2 (en) 2012-10-02
SG173961A1 (en) 2011-09-29
CN103265491B (zh) 2015-01-21
TW201144287A (en) 2011-12-16
HRP20120955T1 (hr) 2012-12-31
KR20110095210A (ko) 2011-08-24
RS52529B (en) 2013-04-30
DK2364972T3 (da) 2013-01-07
TWI395738B (zh) 2013-05-11
AU2011200403A1 (en) 2011-09-01
UA106208C2 (ru) 2014-08-11
EP2364972B1 (fr) 2012-09-19
FR2956401A1 (fr) 2011-08-19
EA201100230A1 (ru) 2011-08-30
CA2731315C (fr) 2013-03-26
HK1183488A1 (en) 2013-12-27
ZA201100964B (en) 2011-10-26
JP2011168590A (ja) 2011-09-01
PT2364972E (pt) 2012-10-02
FR2956401B1 (fr) 2012-02-03
ES2396042T3 (es) 2013-02-18
PL2364972T3 (pl) 2013-01-31
CA2731315A1 (fr) 2011-08-17
SI2364972T1 (sl) 2012-12-31
SA111320199B1 (ar) 2014-05-21
MY147697A (en) 2013-01-07
MA32681B1 (fr) 2011-10-02
WO2011101558A1 (fr) 2011-08-25
CY1113338T1 (el) 2016-06-22
GEP20135737B (en) 2013-01-25
JO2854B1 (en) 2015-03-15
PE20120576A1 (es) 2012-05-12
HK1162021A1 (en) 2012-08-17
CN103232360A (zh) 2013-08-07
CN103232360B (zh) 2014-05-21
HK1183295A1 (en) 2013-12-20
AU2011200403B2 (en) 2015-02-19
CN102161642A (zh) 2011-08-24

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