UY33094A - Procedimiento para la preparacion de dronedarona - Google Patents
Procedimiento para la preparacion de dronedaronaInfo
- Publication number
- UY33094A UY33094A UY33094A UY33094A UY33094A UY 33094 A UY33094 A UY 33094A UY 33094 A UY33094 A UY 33094A UY 33094 A UY33094 A UY 33094A UY 33094 A UY33094 A UY 33094A
- Authority
- UY
- Uruguay
- Prior art keywords
- dronedarona
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0900759A HUP0900759A2 (en) | 2009-12-08 | 2009-12-08 | Novel process for producing dronedarone |
Publications (1)
Publication Number | Publication Date |
---|---|
UY33094A true UY33094A (es) | 2011-07-29 |
Family
ID=89989418
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY33094A UY33094A (es) | 2009-12-08 | 2010-12-08 | Procedimiento para la preparacion de dronedarona |
Country Status (16)
Country | Link |
---|---|
US (2) | US8501971B2 (es) |
EP (1) | EP2509971A1 (es) |
JP (1) | JP2013512944A (es) |
CN (1) | CN102741238A (es) |
AR (1) | AR079269A1 (es) |
AU (1) | AU2010329655B2 (es) |
BR (1) | BR112012013753A2 (es) |
CA (1) | CA2781647A1 (es) |
HU (1) | HUP0900759A2 (es) |
IL (1) | IL220170A0 (es) |
MX (1) | MX2012006654A (es) |
RU (1) | RU2012128568A (es) |
SG (1) | SG181562A1 (es) |
TW (1) | TW201144291A (es) |
UY (1) | UY33094A (es) |
WO (1) | WO2011070380A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0900759A2 (en) * | 2009-12-08 | 2011-11-28 | Sanofi Aventis | Novel process for producing dronedarone |
IT1398317B1 (it) * | 2010-02-23 | 2013-02-22 | Chimico Internaz Spa Lab | Nuovo procedimento per la preparazione del dronedarone. |
FR2957079B1 (fr) | 2010-03-02 | 2012-07-27 | Sanofi Aventis | Procede de synthese de derives de cetobenzofurane |
FR2958290B1 (fr) | 2010-03-30 | 2012-10-19 | Sanofi Aventis | Procede de preparation de derives de sulfonamido-benzofurane |
FR2958291B1 (fr) | 2010-04-01 | 2013-07-05 | Sanofi Aventis | Procede de preparation de derives d'amino-benzofurane |
HUP1000330A2 (en) | 2010-06-18 | 2011-12-28 | Sanofi Sa | Process for the preparation of dronedarone and the novel intermediates |
WO2012004658A2 (en) * | 2010-07-09 | 2012-01-12 | Frichem Private Limited | Process for preparation of n-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide, acid addition salts and product thereof |
FR2962731B1 (fr) | 2010-07-19 | 2012-08-17 | Sanofi Aventis | Procede de preparation de derives d'amino-benzoyl-benzofurane |
FR2963006B1 (fr) | 2010-07-21 | 2013-03-15 | Sanofi Aventis | Procede de preparation de derives de nitro-benzofurane |
HUP1000386A2 (en) | 2010-07-22 | 2012-05-29 | Sanofi Sa | Novel process for producing dronedarone |
WO2012032545A1 (en) | 2010-09-08 | 2012-03-15 | Cadila Healthcare Limited | Processes for preparing dronedarone and its intermediates |
CN102653530A (zh) * | 2011-03-04 | 2012-09-05 | 浙江省医学科学院 | 一种苯并呋喃衍生物的制备方法及其应用 |
HUP1100167A2 (en) | 2011-03-29 | 2012-11-28 | Sanofi Sa | Process for preparation of dronedarone by mesylation |
HUP1100165A2 (en) | 2011-03-29 | 2012-12-28 | Sanofi Sa | Process for preparation of dronedarone by n-butylation |
WO2013014478A1 (en) * | 2011-07-26 | 2013-01-31 | Sanofi | Reductive amination process for preparation of dronedarone using carboxyl intermediary compound |
WO2013014479A1 (en) * | 2011-07-26 | 2013-01-31 | Sanofi | Reductive animation process for preparation of dronedarone using aldehyde intermediary compound |
FR2983198B1 (fr) * | 2011-11-29 | 2013-11-15 | Sanofi Sa | Procede de preparation de derives de 5-amino-benzoyl-benzofurane |
EP2617718A1 (en) | 2012-01-20 | 2013-07-24 | Sanofi | Process for preparation of dronedarone by the use of dibutylaminopropanol reagent |
US9221778B2 (en) | 2012-02-13 | 2015-12-29 | Sanofi | Process for preparation of dronedarone by removal of hydroxyl group |
WO2013121234A1 (en) | 2012-02-14 | 2013-08-22 | Sanofi | Process for the preparation of dronedarone by oxidation of a sulphenyl group |
US9382223B2 (en) | 2012-02-22 | 2016-07-05 | Sanofi | Process for preparation of dronedarone by oxidation of a hydroxyl group |
US9238636B2 (en) | 2012-05-31 | 2016-01-19 | Sanofi | Process for preparation of dronedarone by Grignard reaction |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2665444B1 (fr) | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
FR2817865B1 (fr) | 2000-12-11 | 2005-02-18 | Sanofi Synthelabo | Derive aminoalkoxybenzoyle sous forme de sel, son procede de preparation et son utilisation comme intermediaire de synthese |
FR2817864B1 (fr) | 2000-12-11 | 2003-02-21 | Sanofi Synthelabo | Derive de methanesulfonamido-benzofurane, son procede de preparation et son utilisation comme intermediaire de synthese |
IL146389A0 (en) * | 2001-11-08 | 2002-07-25 | Isp Finetech Ltd | Process for the preparation of dronedarone |
FR2833262A1 (fr) | 2001-12-06 | 2003-06-13 | Rhodia Chimie Sa | Procede de monosulfonylation d'un compose de type aminobenzofuranne ou aminobenzothiophene |
DE10237819A1 (de) | 2002-08-19 | 2004-03-04 | Bayer Ag | 5-Nitrobenzofurane |
CN101153012B (zh) * | 2006-09-29 | 2010-06-23 | 北京德众万全药物技术开发有限公司 | 一种决奈达隆关键中间体的新的制备方法 |
TW201111354A (en) | 2009-05-27 | 2011-04-01 | Sanofi Aventis | Process for the production of Dronedarone intermediates |
UY32656A (es) | 2009-05-27 | 2010-12-31 | Sanofi Aventis | Procedimiento para producir benzofuranos |
HUP0900759A2 (en) * | 2009-12-08 | 2011-11-28 | Sanofi Aventis | Novel process for producing dronedarone |
HUP1000010A2 (en) | 2010-01-08 | 2011-11-28 | Sanofi Sa | Process for producing dronedarone |
FR2957079B1 (fr) | 2010-03-02 | 2012-07-27 | Sanofi Aventis | Procede de synthese de derives de cetobenzofurane |
FR2958290B1 (fr) | 2010-03-30 | 2012-10-19 | Sanofi Aventis | Procede de preparation de derives de sulfonamido-benzofurane |
FR2958291B1 (fr) | 2010-04-01 | 2013-07-05 | Sanofi Aventis | Procede de preparation de derives d'amino-benzofurane |
HUP1000330A2 (en) | 2010-06-18 | 2011-12-28 | Sanofi Sa | Process for the preparation of dronedarone and the novel intermediates |
FR2962731B1 (fr) | 2010-07-19 | 2012-08-17 | Sanofi Aventis | Procede de preparation de derives d'amino-benzoyl-benzofurane |
FR2963006B1 (fr) | 2010-07-21 | 2013-03-15 | Sanofi Aventis | Procede de preparation de derives de nitro-benzofurane |
HUP1000386A2 (en) | 2010-07-22 | 2012-05-29 | Sanofi Sa | Novel process for producing dronedarone |
FR2973027A1 (fr) | 2011-03-24 | 2012-09-28 | Sanofi Aventis | Procede de synthese de derives de cetobenzofurane |
HUP1100165A2 (en) | 2011-03-29 | 2012-12-28 | Sanofi Sa | Process for preparation of dronedarone by n-butylation |
HUP1100167A2 (en) | 2011-03-29 | 2012-11-28 | Sanofi Sa | Process for preparation of dronedarone by mesylation |
HUP1100166A2 (en) | 2011-03-29 | 2012-12-28 | Sanofi Sa | Reductive amination process for preparation of dronedarone using amine intermediary compound |
-
2009
- 2009-12-08 HU HU0900759A patent/HUP0900759A2/hu unknown
-
2010
- 2010-11-23 MX MX2012006654A patent/MX2012006654A/es not_active Application Discontinuation
- 2010-11-23 RU RU2012128568/04A patent/RU2012128568A/ru not_active Application Discontinuation
- 2010-11-23 EP EP10809325A patent/EP2509971A1/en not_active Withdrawn
- 2010-11-23 WO PCT/HU2010/000128 patent/WO2011070380A1/en active Application Filing
- 2010-11-23 BR BR112012013753A patent/BR112012013753A2/pt not_active IP Right Cessation
- 2010-11-23 SG SG2012041927A patent/SG181562A1/en unknown
- 2010-11-23 AU AU2010329655A patent/AU2010329655B2/en not_active Ceased
- 2010-11-23 CN CN2010800629901A patent/CN102741238A/zh active Pending
- 2010-11-23 JP JP2012542624A patent/JP2013512944A/ja not_active Withdrawn
- 2010-11-23 CA CA2781647A patent/CA2781647A1/en not_active Abandoned
- 2010-12-06 AR ARP100104488A patent/AR079269A1/es unknown
- 2010-12-07 TW TW099142501A patent/TW201144291A/zh unknown
- 2010-12-08 UY UY33094A patent/UY33094A/es not_active Application Discontinuation
-
2012
- 2012-05-24 US US13/479,615 patent/US8501971B2/en active Active
- 2012-06-04 IL IL220170A patent/IL220170A0/en unknown
-
2013
- 2013-05-30 US US13/905,624 patent/US8889734B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2011070380A1 (en) | 2011-06-16 |
MX2012006654A (es) | 2012-06-25 |
US8889734B2 (en) | 2014-11-18 |
JP2013512944A (ja) | 2013-04-18 |
SG181562A1 (en) | 2012-07-30 |
AR079269A1 (es) | 2012-01-04 |
AU2010329655B2 (en) | 2014-01-16 |
BR112012013753A2 (pt) | 2015-09-15 |
IL220170A0 (en) | 2012-07-31 |
CN102741238A (zh) | 2012-10-17 |
HU0900759D0 (en) | 2010-01-28 |
HUP0900759A2 (en) | 2011-11-28 |
TW201144291A (en) | 2011-12-16 |
CA2781647A1 (en) | 2011-06-16 |
US20130261321A1 (en) | 2013-10-03 |
US20120289717A1 (en) | 2012-11-15 |
EP2509971A1 (en) | 2012-10-17 |
RU2012128568A (ru) | 2014-01-20 |
US8501971B2 (en) | 2013-08-06 |
AU2010329655A1 (en) | 2012-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20181127 |