UY30652A1 - N-(2-hidroxietil)-n-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)piperidin-4-ilideno)metil)benzamida - Google Patents
N-(2-hidroxietil)-n-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)piperidin-4-ilideno)metil)benzamidaInfo
- Publication number
- UY30652A1 UY30652A1 UY30652A UY30652A UY30652A1 UY 30652 A1 UY30652 A1 UY 30652A1 UY 30652 A UY30652 A UY 30652A UY 30652 A UY30652 A UY 30652A UY 30652 A1 UY30652 A1 UY 30652A1
- Authority
- UY
- Uruguay
- Prior art keywords
- methyl
- quinolin
- piperidin
- hydroxyethyl
- benzamide
- Prior art date
Links
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title abstract 4
- -1 2-HYDROXYETHYL Chemical class 0.000 title abstract 3
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- ZJKUETLEJYCOBO-UHFFFAOYSA-N n-(2-hydroxyethyl)-n-methyl-4-[quinolin-8-yl-[1-(1,3-thiazol-4-ylmethyl)piperidin-4-ylidene]methyl]benzamide Chemical compound C1=CC(C(=O)N(CCO)C)=CC=C1C(C=1C2=NC=CC=C2C=CC=1)=C1CCN(CC=2N=CSC=2)CC1 ZJKUETLEJYCOBO-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86232706P | 2006-10-20 | 2006-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY30652A1 true UY30652A1 (es) | 2008-05-31 |
Family
ID=39314285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY30652A UY30652A1 (es) | 2006-10-20 | 2007-10-19 | N-(2-hidroxietil)-n-metil-4-(quinolin-8-il(1-(tiazol-4-ilmetil)piperidin-4-ilideno)metil)benzamida |
Country Status (32)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060010811A (ko) * | 2003-05-16 | 2006-02-02 | 아스트라제네카 아베 | 디아릴메틸리덴 피페리딘 유도체, 그의 제조 및 그의 용도 |
| MY148880A (en) * | 2006-10-20 | 2013-06-14 | Astrazeneca Ab | N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression |
| JP2011520956A (ja) * | 2008-05-20 | 2011-07-21 | アストラゼネカ・アクチエボラーグ | 不安大うつ病性障害を処置する方法 |
| CN101906078B (zh) * | 2009-06-08 | 2012-02-01 | 上海威智医药科技有限公司 | 噻唑衍生物的合成方法 |
| CN102106807B (zh) * | 2009-12-29 | 2013-03-27 | 上海中西制药有限公司 | 一种固体制剂的制备方法及所得固体制剂 |
| DK3233825T3 (da) * | 2014-12-19 | 2020-06-29 | Pharmnovo Ab | Diarylmethylidenpiperidinderivater og deres anvendelse som deltaopioidreceptoragonister |
| US11286728B2 (en) | 2018-09-21 | 2022-03-29 | Postle Industries, Inc. | Helical hardbanding |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| DK1049676T3 (da) * | 1997-12-24 | 2006-01-16 | Ortho Mcneil Pharm Inc | 4-[Aryl(piperidin-4-yl)]aminobenzamider, som binder til delta-opioidreceptoren |
| US6492375B2 (en) | 1998-06-30 | 2002-12-10 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
| SE9904673D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| EP1242398A2 (en) | 1999-12-20 | 2002-09-25 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
| US6552036B2 (en) | 2000-03-03 | 2003-04-22 | Ortho-Mcneil Pharmaceutical, Inc. | 3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives |
| SE0001208D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| SE0101768D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| US20040204404A1 (en) | 2002-09-30 | 2004-10-14 | Robert Zelle | Human N-type calcium channel blockers |
| SE0300105D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof |
| SE0301442D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| KR20060010811A (ko) | 2003-05-16 | 2006-02-02 | 아스트라제네카 아베 | 디아릴메틸리덴 피페리딘 유도체, 그의 제조 및 그의 용도 |
| SE0301444D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301445D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301441D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0400025D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| WO2005087742A1 (en) | 2004-03-08 | 2005-09-22 | Exelixis, Inc. | Metabolic kinase modulators and methods of use as pesticides |
| MY148880A (en) | 2006-10-20 | 2013-06-14 | Astrazeneca Ab | N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression |
-
2007
- 2007-10-09 MY MYPI20091593A patent/MY148880A/en unknown
- 2007-10-18 TW TW096139052A patent/TW200826939A/zh unknown
- 2007-10-19 WO PCT/SE2007/000924 patent/WO2008048171A1/en not_active Ceased
- 2007-10-19 PT PT07835125T patent/PT2079735E/pt unknown
- 2007-10-19 UY UY30652A patent/UY30652A1/es not_active Application Discontinuation
- 2007-10-19 NZ NZ577060A patent/NZ577060A/en not_active IP Right Cessation
- 2007-10-19 RS RS20120166A patent/RS52260B/sr unknown
- 2007-10-19 CA CA2667041A patent/CA2667041C/en not_active Expired - Fee Related
- 2007-10-19 AR ARP070104641A patent/AR063345A1/es not_active Application Discontinuation
- 2007-10-19 ES ES07835125T patent/ES2379519T3/es active Active
- 2007-10-19 CN CN2007800390975A patent/CN101528739B/zh not_active Expired - Fee Related
- 2007-10-19 AU AU2007313515A patent/AU2007313515B2/en not_active Ceased
- 2007-10-19 PL PL07835125T patent/PL2079735T3/pl unknown
- 2007-10-19 KR KR1020097007893A patent/KR20090065534A/ko not_active Ceased
- 2007-10-19 DK DK07835125.1T patent/DK2079735T3/da active
- 2007-10-19 BR BRPI0717631-7A patent/BRPI0717631A2/pt not_active IP Right Cessation
- 2007-10-19 HR HRP20120344TT patent/HRP20120344T1/hr unknown
- 2007-10-19 US US11/875,014 patent/US7659286B2/en not_active Expired - Fee Related
- 2007-10-19 JP JP2009533278A patent/JP4668346B2/ja not_active Expired - Fee Related
- 2007-10-19 UA UAA200903085A patent/UA97648C2/ru unknown
- 2007-10-19 MX MX2009003974A patent/MX2009003974A/es active IP Right Grant
- 2007-10-19 SI SI200730905T patent/SI2079735T1/sl unknown
- 2007-10-19 CL CL200703009A patent/CL2007003009A1/es unknown
- 2007-10-19 PE PE2007001423A patent/PE20080892A1/es not_active Application Discontinuation
- 2007-10-19 EP EP07835125A patent/EP2079735B1/en active Active
- 2007-10-19 AT AT07835125T patent/ATE543818T1/de active
- 2007-10-19 RU RU2009111337/04A patent/RU2454414C2/ru not_active IP Right Cessation
- 2007-10-20 SA SA7280549A patent/SA07280549B1/ar unknown
-
2009
- 2009-03-26 IL IL197876A patent/IL197876A0/en unknown
- 2009-03-31 CO CO0903310009033100A patent/CO6180450A2/es not_active Application Discontinuation
- 2009-05-20 NO NO20091969A patent/NO20091969L/no not_active Application Discontinuation
- 2009-12-21 US US12/643,202 patent/US7977355B2/en not_active Expired - Fee Related
-
2010
- 2010-10-06 AU AU2010226996A patent/AU2010226996A1/en not_active Abandoned
-
2012
- 2012-04-25 CY CY20121100389T patent/CY1112718T1/el unknown
- 2012-07-24 PE PE2012001060A patent/PE20140634A1/es not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20170727 |