UY30468A1 - Compuestos quimicos. - Google Patents
Compuestos quimicos.Info
- Publication number
- UY30468A1 UY30468A1 UY30468A UY30468A UY30468A1 UY 30468 A1 UY30468 A1 UY 30468A1 UY 30468 A UY30468 A UY 30468A UY 30468 A UY30468 A UY 30468A UY 30468 A1 UY30468 A1 UY 30468A1
- Authority
- UY
- Uruguay
- Prior art keywords
- chemical compounds
- conditions
- compounds
- dioxoalkenes
- dioxoalkanes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 206010027654 Allergic conditions Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 208000029578 Muscle disease Diseases 0.000 abstract 1
- 208000021642 Muscular disease Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 230000004968 inflammatory condition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/22—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
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- C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
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- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
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- C—CHEMISTRY; METALLURGY
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- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
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- Gynecology & Obstetrics (AREA)
Abstract
Dioxoalcanos y dioxoalquenos susitutídos utiles para el tratamiento o profilaxis de la hipersensibilidad, desordenes de musculo liso, condiciones espasmodicas, condiciones alérgicas, condiciones inflamatorias y/o dolor, composiciones farmacéuticas que comprenden dichos compuestos y métodos de preparacion de los mismos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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GBGB0613518.0A GB0613518D0 (en) | 2006-07-06 | 2006-07-06 | Chemical compounds |
Publications (1)
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UY30468A1 true UY30468A1 (es) | 2008-05-31 |
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UY30468A UY30468A1 (es) | 2006-07-06 | 2007-07-06 | Compuestos quimicos. |
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US (1) | US7589123B2 (es) |
EP (1) | EP2046311A2 (es) |
JP (1) | JP5397903B2 (es) |
CN (1) | CN101511350A (es) |
AR (1) | AR061955A1 (es) |
AU (1) | AU2007270951B2 (es) |
CA (1) | CA2660182A1 (es) |
CL (1) | CL2007001976A1 (es) |
GB (2) | GB0613518D0 (es) |
HK (1) | HK1114600A1 (es) |
MX (1) | MX2009000283A (es) |
PE (1) | PE20080274A1 (es) |
TW (1) | TW200819122A (es) |
UY (1) | UY30468A1 (es) |
WO (1) | WO2008003978A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2008006032A1 (en) | 2006-07-06 | 2008-01-10 | Array Biopharma Inc. | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
ATE532789T1 (de) | 2006-07-06 | 2011-11-15 | Array Biopharma Inc | Dihydrothienopyrimidine als akt-proteinkinase- inhibitoren |
US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
US8329701B2 (en) | 2006-07-06 | 2012-12-11 | Array Biopharma Inc. | Dihydrofuro pyrimidines as AKT protein kinase inhibitors |
US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
EP2173723B3 (en) | 2007-07-05 | 2014-11-19 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as akt protein kinase inhibitors |
RU2486181C2 (ru) | 2007-07-05 | 2013-06-27 | Эррэй Биофарма Инк. | Пиримидилциклопентаны как ингибиторы акт-протеинкиназ |
US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
AU2009204019B2 (en) | 2008-01-09 | 2014-02-20 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentane as AKT protein kinase inhibitor |
ES2422733T3 (es) | 2008-01-09 | 2013-09-13 | Array Biopharma Inc | Pirimidilciclopentanos hidroxilados como inhibidores de proteínas cinasas AKT |
CN102348668B (zh) * | 2009-01-12 | 2014-11-19 | 培力有限公司 | 化合物及其用于治疗炎症和调节免疫应答的用途 |
CN103857395A (zh) | 2011-04-01 | 2014-06-11 | 基因泰克公司 | Akt抑制剂化合物和阿比特龙的组合及使用方法 |
JP6147246B2 (ja) | 2011-04-01 | 2017-06-14 | ジェネンテック, インコーポレイテッド | Akt及びmek阻害剤化合物の組み合わせ、及び使用方法 |
KR101369882B1 (ko) * | 2012-01-17 | 2014-03-26 | 한국화학연구원 | (4-하이드록시-3-메톡시페닐)부테논 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 천식 예방 또는 치료용 약학적 조성물 |
US8754084B2 (en) | 2012-03-27 | 2014-06-17 | The Board Of Trustees Of The University Of Illinois | Therapeutic methods and agents for treating myotonic dystrophy |
WO2014087331A2 (en) * | 2012-12-06 | 2014-06-12 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurologic diseases |
US9376421B2 (en) | 2014-08-08 | 2016-06-28 | The Board Of Trustees Of The University Of Illinois | Compounds and methods for myotonic dystrophy therapy |
US11135318B2 (en) * | 2016-06-29 | 2021-10-05 | The General Hospital Corporation | Half-curcuminoids as amyloid-beta PET imaging agents |
WO2019040750A1 (en) | 2017-08-25 | 2019-02-28 | The Board Of Trustees Of The University Of Illinois | MULTIVALENT LIGAND FOR MYOTONIC DYSTROPHY |
CN115894241A (zh) * | 2022-10-17 | 2023-04-04 | 深圳凯联健康生物科技有限公司 | 咖啡活性酚、组合物及其在制备具有促进肠蠕动作用和/或缓解便秘作用的产品中的应用 |
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DE1133385B (de) * | 1960-04-14 | 1962-07-19 | Zyma Blaes A G Chem Fab | Verfahren zur Herstellung von 3-Pyrazyl-pyrazolderivaten |
US4649157A (en) * | 1986-03-28 | 1987-03-10 | G. D. Searle & Co. | Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds |
US4810716A (en) | 1986-04-11 | 1989-03-07 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
AU624366B2 (en) | 1988-03-02 | 1992-06-11 | Terumo Kabushiki Kaisha | Catechol compounds, process for their preparation and pharmaceutical preparation containing same |
ZA941088B (en) | 1993-02-19 | 1995-09-27 | Symphar Sa | Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them |
JP3376016B2 (ja) * | 1993-05-31 | 2003-02-10 | 塩野義製薬株式会社 | カルバペネムの合成中間体の製造方法 |
US6518315B1 (en) * | 1997-10-21 | 2003-02-11 | The University Of Sydney | Medicinal uses of phenylaikanols and derivatives |
JP2003306438A (ja) * | 2002-02-18 | 2003-10-28 | Shiseido Co Ltd | ケモカイン発現阻害剤 |
MXPA05001334A (es) * | 2002-08-02 | 2005-09-08 | Argenta Discovery Ltd | Acidos tienil-hidroxamicos sustituidos como inhibidores de la desacetilasa de histona. |
JP4691988B2 (ja) | 2002-10-03 | 2011-06-01 | 小野薬品工業株式会社 | Lpa受容体拮抗剤 |
WO2004037793A1 (ja) * | 2002-10-24 | 2004-05-06 | Wakamoto Pharmaceutical Co., Ltd. | シクロオキシゲナーゼ及び5−リポキシゲナーゼを阻害するピラゾール−4−アルカン酸誘導体 |
GB0308318D0 (en) * | 2003-04-10 | 2003-05-14 | Merck Sharp & Dohme | Therapeutic agents |
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2007
- 2007-07-05 PE PE2007000872A patent/PE20080274A1/es not_active Application Discontinuation
- 2007-07-05 GB GB0713117A patent/GB2440034B/en not_active Expired - Fee Related
- 2007-07-05 CA CA002660182A patent/CA2660182A1/en not_active Abandoned
- 2007-07-05 US US11/773,952 patent/US7589123B2/en not_active Expired - Fee Related
- 2007-07-05 MX MX2009000283A patent/MX2009000283A/es active IP Right Grant
- 2007-07-05 CL CL200701976A patent/CL2007001976A1/es unknown
- 2007-07-05 EP EP07733478A patent/EP2046311A2/en not_active Withdrawn
- 2007-07-05 AR ARP070103007A patent/AR061955A1/es unknown
- 2007-07-05 JP JP2009517431A patent/JP5397903B2/ja not_active Expired - Fee Related
- 2007-07-05 WO PCT/GB2007/002527 patent/WO2008003978A2/en active Application Filing
- 2007-07-05 CN CNA2007800255371A patent/CN101511350A/zh active Pending
- 2007-07-05 AU AU2007270951A patent/AU2007270951B2/en not_active Expired - Fee Related
- 2007-07-05 TW TW096124462A patent/TW200819122A/zh unknown
- 2007-07-06 UY UY30468A patent/UY30468A1/es not_active Application Discontinuation
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2008
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Also Published As
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US20080045591A1 (en) | 2008-02-21 |
US7589123B2 (en) | 2009-09-15 |
CA2660182A1 (en) | 2008-01-10 |
JP5397903B2 (ja) | 2014-01-22 |
HK1114600A1 (en) | 2008-11-07 |
MX2009000283A (es) | 2009-01-26 |
JP2009544577A (ja) | 2009-12-17 |
CN101511350A (zh) | 2009-08-19 |
CL2007001976A1 (es) | 2008-05-16 |
EP2046311A2 (en) | 2009-04-15 |
PE20080274A1 (es) | 2008-04-10 |
GB2440034B (en) | 2011-02-16 |
WO2008003978A3 (en) | 2008-12-31 |
AU2007270951A1 (en) | 2008-01-10 |
WO2008003978A2 (en) | 2008-01-10 |
AR061955A1 (es) | 2008-08-10 |
GB2440034A (en) | 2008-01-16 |
TW200819122A (en) | 2008-05-01 |
AU2007270951B2 (en) | 2013-04-11 |
GB0613518D0 (en) | 2006-08-16 |
GB0713117D0 (en) | 2007-08-15 |
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