UY30330A1 - Nuevas formas polimorfas de (2s)-(4e)-n-metil-5-(3-(5-isopropoxipiridin)il)-4-penten-2-amina - Google Patents

Nuevas formas polimorfas de (2s)-(4e)-n-metil-5-(3-(5-isopropoxipiridin)il)-4-penten-2-amina

Info

Publication number
UY30330A1
UY30330A1 UY30330A UY30330A UY30330A1 UY 30330 A1 UY30330 A1 UY 30330A1 UY 30330 A UY30330 A UY 30330A UY 30330 A UY30330 A UY 30330A UY 30330 A1 UY30330 A1 UY 30330A1
Authority
UY
Uruguay
Prior art keywords
penten
isopropoxipiridin
metil
amina
polymorph forms
Prior art date
Application number
UY30330A
Other languages
English (en)
Inventor
Julio A Munoz
Gary Maurice Dull
Original Assignee
Targacept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targacept Inc filed Critical Targacept Inc
Publication of UY30330A1 publication Critical patent/UY30330A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Se revelan formas polimorfas de p-hidroxibenzoato de (2S)-(4E)-N-metil-5- [ 3-( 5-isopropoxipiridin) il ] -4-penten-2-amina y métodos para su preparacion, composicion farmacéutica que contiene dichas formas polimorfas y su uso. Las polimorfas pueden administrarse a pacientes como por ejemplo trastornos del sistema nervioso central, para tratar y/o prevenir dichos trastornos.
UY30330A 2006-05-09 2007-05-07 Nuevas formas polimorfas de (2s)-(4e)-n-metil-5-(3-(5-isopropoxipiridin)il)-4-penten-2-amina UY30330A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74682106P 2006-05-09 2006-05-09

Publications (1)

Publication Number Publication Date
UY30330A1 true UY30330A1 (es) 2008-10-31

Family

ID=38441430

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30330A UY30330A1 (es) 2006-05-09 2007-05-07 Nuevas formas polimorfas de (2s)-(4e)-n-metil-5-(3-(5-isopropoxipiridin)il)-4-penten-2-amina

Country Status (29)

Country Link
US (3) US8461344B2 (es)
EP (2) EP2418201B1 (es)
JP (1) JP4477097B2 (es)
KR (1) KR20090005369A (es)
CN (1) CN101472893A (es)
AR (1) AR060786A1 (es)
AU (1) AU2007249485B2 (es)
BR (1) BRPI0709781A2 (es)
CA (1) CA2649961A1 (es)
DK (1) DK2418201T3 (es)
EC (1) ECSP088876A (es)
ES (1) ES2460919T3 (es)
HR (1) HRP20140385T1 (es)
IL (1) IL194833A0 (es)
MX (1) MX2008013982A (es)
MY (1) MY144132A (es)
NO (1) NO20084567L (es)
NZ (1) NZ597177A (es)
PL (1) PL2418201T3 (es)
PT (1) PT2418201E (es)
RS (1) RS53286B (es)
RU (1) RU2440984C2 (es)
SA (1) SA07280230B1 (es)
SI (1) SI2418201T1 (es)
TW (1) TWI389889B (es)
UA (1) UA96447C2 (es)
UY (1) UY30330A1 (es)
WO (1) WO2007134034A1 (es)
ZA (1) ZA200809284B (es)

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US7790757B2 (en) 1998-06-16 2010-09-07 Targacept, Inc. Compounds capable of activating cholinergic receptors
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
UA88792C2 (ru) * 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
EP2133337A1 (en) * 2006-05-09 2009-12-16 AstraZeneca AB Salt forms of (2S)-(4E)-N-Methyl-5-[(5-Isopropoxy)pyridin-3-yl]-4-penten-2-amine
TWI389889B (zh) 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
CL2007002684A1 (es) * 2006-09-15 2008-06-27 Astrazeneca Ab Targacept Inc Combinacion que comprende un antipsicotico y (2s)-(4e)-n-metil-5-[3-(5-isopropoxipiridin)il]-4-penten-2-amina; composicion farmaceutica que la comprende; kit farmaceutico; y uso para tratar perjuicio cognitivo y/o trastorno psicoticos.
US20100028447A1 (en) * 2007-01-22 2010-02-04 Targacept, Inc. Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs
US20100247617A1 (en) * 2007-07-31 2010-09-30 Targacept, Inc. Transdermal Administration Of (2S)-(4E)-N-Methyl-5-(3-(5-Isopropoxypyridin)yl)-4-Penten-2-Amine
US20110130428A1 (en) * 2008-06-11 2011-06-02 Astrazeneca Ab Sublingual Compositions Comprising (2S) - (4E) -N-Methyl-5- (3- (5-Isopropoxypyridin) YL)-4-Penten-2-Amine
WO2010080757A2 (en) * 2009-01-07 2010-07-15 Astrazeneca Ab Combinations with an alpha-4beta-2 nicotinic agonist
FR2959107B1 (fr) 2010-04-23 2015-03-27 Oreal Unite d'application d'un produit cosmetique
US8703802B2 (en) * 2010-05-20 2014-04-22 Targacept, Inc. Process for the preparation of aryl substituted olefinic amines
WO2013184732A1 (en) * 2012-06-06 2013-12-12 Targacept, Inc. Crystalline (2s)-(4e)-n-methyl-5-[3-(5-isopropoxypyridin)yl]4-penten-2-amine 1,5-naphthalenedisulfonate
KR101579904B1 (ko) 2014-09-05 2016-01-05 동신대학교산학협력단 마스카라

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Also Published As

Publication number Publication date
AR060786A1 (es) 2008-07-10
MY144132A (en) 2011-08-15
SI2418201T1 (sl) 2014-06-30
UA96447C2 (ru) 2011-11-10
JP2009531465A (ja) 2009-09-03
JP4477097B2 (ja) 2010-06-09
EP2021326A1 (en) 2009-02-11
IL194833A0 (en) 2009-08-03
DK2418201T3 (da) 2014-05-12
NZ597177A (en) 2013-06-28
ECSP088876A (es) 2009-02-27
PT2418201E (pt) 2014-04-14
US20070265314A1 (en) 2007-11-15
BRPI0709781A2 (pt) 2011-07-26
RU2440984C2 (ru) 2012-01-27
CN101472893A (zh) 2009-07-01
ZA200809284B (en) 2009-08-26
US8461344B2 (en) 2013-06-11
PL2418201T3 (pl) 2014-07-31
AU2007249485B2 (en) 2012-11-01
AU2007249485A1 (en) 2007-11-22
RU2008148325A (ru) 2010-06-20
US20130310425A1 (en) 2013-11-21
ES2460919T3 (es) 2014-05-16
TWI389889B (zh) 2013-03-21
US20100048643A1 (en) 2010-02-25
EP2418201A1 (en) 2012-02-15
TW200808726A (en) 2008-02-16
CA2649961A1 (en) 2007-11-22
WO2007134034A1 (en) 2007-11-22
KR20090005369A (ko) 2009-01-13
EP2418201B1 (en) 2014-02-12
NO20084567L (no) 2008-12-04
RS53286B (en) 2014-08-29
SA07280230B1 (ar) 2010-08-20
MX2008013982A (es) 2009-03-13
HRP20140385T1 (hr) 2014-06-06

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