UY29042A1 - Derivados de ácido benzoico como inhibidores no nucleósidos de la transcriptasa inversa - Google Patents

Derivados de ácido benzoico como inhibidores no nucleósidos de la transcriptasa inversa

Info

Publication number
UY29042A1
UY29042A1 UY29042A UY29042A UY29042A1 UY 29042 A1 UY29042 A1 UY 29042A1 UY 29042 A UY29042 A UY 29042A UY 29042 A UY29042 A UY 29042A UY 29042 A1 UY29042 A1 UY 29042A1
Authority
UY
Uruguay
Prior art keywords
inhibitors
nucleosid
derivatives
benzoic acid
reverse transcript
Prior art date
Application number
UY29042A
Other languages
English (en)
Spanish (es)
Inventor
Bruno Simoneau
Christiane Yoakim
Jeffrey O Meara
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of UY29042A1 publication Critical patent/UY29042A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/68Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/24Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
UY29042A 2004-08-02 2005-07-29 Derivados de ácido benzoico como inhibidores no nucleósidos de la transcriptasa inversa UY29042A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59822704P 2004-08-02 2004-08-02

Publications (1)

Publication Number Publication Date
UY29042A1 true UY29042A1 (es) 2006-03-31

Family

ID=35786846

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29042A UY29042A1 (es) 2004-08-02 2005-07-29 Derivados de ácido benzoico como inhibidores no nucleósidos de la transcriptasa inversa

Country Status (10)

Country Link
US (2) US20060025480A1 (https=)
EP (1) EP1781600B1 (https=)
JP (1) JP4847450B2 (https=)
AR (1) AR050032A1 (https=)
AT (1) ATE526309T1 (https=)
CA (1) CA2573315C (https=)
PE (1) PE20060384A1 (https=)
TW (1) TW200616933A (https=)
UY (1) UY29042A1 (https=)
WO (1) WO2006012733A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5036543B2 (ja) * 2004-09-30 2012-09-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 非ヌクレオシド逆転写酵素インヒビターとしてのベンゾフェノンのアルキニル誘導体
CL2008001631A1 (es) * 2007-06-06 2009-01-02 Smithkline Beecham Corp Compuestos derivados de heterociclos sustituidos, con la presencia de un grupo fenoxi, inhibidores de transcriptasa inversa; composicion farmaceutica; y uso en el tratamiento de infecciones virales por vih.
US8242140B2 (en) * 2007-08-03 2012-08-14 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
JP2010535155A (ja) * 2007-08-03 2010-11-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウイルスポリメラーゼ阻害剤
EP2234977A4 (en) 2007-12-19 2011-04-13 Boehringer Ingelheim Int VIRAL POLYMERASE INHIBITORS
CN102219717A (zh) * 2011-04-20 2011-10-19 复旦大学 N-苯基芳基甲酰胺衍生物及其制备方法和用途
CN102212022A (zh) * 2011-04-20 2011-10-12 复旦大学 二苯甲醇衍生物及其制备方法和用途
CN102206177A (zh) * 2011-04-20 2011-10-05 复旦大学 1-萘基苯甲酮衍生物及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920872D0 (en) * 1999-09-04 1999-11-10 Glaxo Group Ltd Benzophenones as inhibitors of reverse transcriptase
TWI270547B (en) 2000-06-16 2007-01-11 Boehringer Ingelheim Ca Ltd Non-nucleoside reverse transcriptase inhibitors
JP2004525914A (ja) * 2001-03-02 2004-08-26 スミスクライン ビーチャム コーポレーション 逆転写酵素阻害剤としてのベンゾフェノン類
JPWO2003030937A1 (ja) 2001-10-05 2005-01-20 小野薬品工業株式会社 ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤
JP4627987B2 (ja) 2002-03-11 2011-02-09 テイボテク・フアーマシユーチカルズ・リミテツド 低分子侵入阻害剤
AU2003254157A1 (en) 2002-07-24 2004-02-09 Ptc Therapeutics, Inc. Acetylamino benzoic acid compounds and their use for nonsense suppression and the treatment of disease
US7642277B2 (en) 2002-12-04 2010-01-05 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors

Also Published As

Publication number Publication date
CA2573315C (en) 2011-03-29
EP1781600A1 (en) 2007-05-09
US20080114068A1 (en) 2008-05-15
CA2573315A1 (en) 2006-02-09
JP4847450B2 (ja) 2011-12-28
EP1781600B1 (en) 2011-09-28
TW200616933A (en) 2006-06-01
ATE526309T1 (de) 2011-10-15
US20060025480A1 (en) 2006-02-02
AR050032A1 (es) 2006-09-20
PE20060384A1 (es) 2006-06-05
JP2008508328A (ja) 2008-03-21
WO2006012733A1 (en) 2006-02-09
US7569723B2 (en) 2009-08-04
EP1781600A4 (en) 2008-12-10

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20160524