UY28120A1 - Derivados de 3h-quinazolin-4-ona - Google Patents

Derivados de 3h-quinazolin-4-ona

Info

Publication number
UY28120A1
UY28120A1 UY28120A UY28120A UY28120A1 UY 28120 A1 UY28120 A1 UY 28120A1 UY 28120 A UY28120 A UY 28120A UY 28120 A UY28120 A UY 28120A UY 28120 A1 UY28120 A1 UY 28120A1
Authority
UY
Uruguay
Prior art keywords
quinazolin
derivatives
ona
obtaining
pharmaceutical compositions
Prior art date
Application number
UY28120A
Other languages
English (en)
Inventor
Andrew William Thomas
Rene Wyler
Rosa Maria Rodriguez Sarmiento
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of UY28120A1 publication Critical patent/UY28120A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms

Abstract

Esta invención se refiere a derivados de la 3H-quinazolin-4-ona definidos en la descripción y en las reivindicaciones, a un proceso para su obtención, a composiciones farmacéuticas que los contienen y a su utilización como inhibidores selectivos de la monoamina-oxidasa B.
UY28120A 2002-12-13 2003-12-11 Derivados de 3h-quinazolin-4-ona UY28120A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02027700 2002-12-13

Publications (1)

Publication Number Publication Date
UY28120A1 true UY28120A1 (es) 2004-06-30

Family

ID=32524001

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28120A UY28120A1 (es) 2002-12-13 2003-12-11 Derivados de 3h-quinazolin-4-ona

Country Status (23)

Country Link
US (1) US7087612B2 (es)
EP (1) EP1572666B1 (es)
JP (1) JP4384053B2 (es)
KR (1) KR100707532B1 (es)
CN (1) CN100418954C (es)
AR (1) AR042362A1 (es)
AT (1) ATE335729T1 (es)
AU (1) AU2003293798B8 (es)
BR (1) BR0317282A (es)
CA (1) CA2509633A1 (es)
CL (1) CL2003002565A1 (es)
DE (1) DE60307512T2 (es)
ES (1) ES2270154T3 (es)
GT (1) GT200300284A (es)
MX (1) MXPA05006124A (es)
MY (1) MY141743A (es)
PA (1) PA8591901A1 (es)
PE (1) PE20040911A1 (es)
PL (1) PL377474A1 (es)
RU (1) RU2340604C2 (es)
TW (1) TW200424180A (es)
UY (1) UY28120A1 (es)
WO (1) WO2004054985A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846915B2 (en) 2004-10-20 2010-12-07 Resverlogix Corporation Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
KR20070094666A (ko) 2005-02-25 2007-09-20 에프. 호프만-라 로슈 아게 약제 물질 분산성이 향상된 정제
NZ566180A (en) 2005-07-29 2011-04-29 Resverlogix Corp Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
GB0525068D0 (en) * 2005-12-08 2006-01-18 Novartis Ag Organic compounds
JP4876690B2 (ja) * 2006-04-21 2012-02-15 三菱瓦斯化学株式会社 キナゾリン−４−オン誘導体の製造法
EP2123627B1 (en) * 2007-01-19 2013-11-20 Ube Industries, Ltd. Process for producing aromatic amine having aralkyloxy or heteroaralkyloxy group
US8053440B2 (en) 2007-02-01 2011-11-08 Resverlogix Corporation Compounds for the prevention and treatment of cardiovascular diseases
RU2520098C2 (ru) 2008-06-26 2014-06-20 Ресверлоджикс Корп. Способы получения производных хиназолинона
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ617779A (en) 2009-03-18 2015-08-28 Resverlogix Corp Novel anti-inflammatory agents
KR20180096823A (ko) 2009-04-22 2018-08-29 리스버로직스 코퍼레이션 신규한 소염제
RS58911B1 (sr) 2011-11-01 2019-08-30 Resverlogix Corp Oralne formulacije sa trenutnim otpuštanjem za supstituisane hinazolinone
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN106146410B (zh) * 2015-04-03 2018-10-12 中南大学 6-氨基-4(3h)-喹唑啉酮衍生物及其合成方法和用途
CN108191667B (zh) * 2018-01-04 2021-03-26 利尔化学股份有限公司 2-硝基-4-三氟甲基苯甲酸甲酯的制备方法
CN109553534A (zh) * 2018-11-27 2019-04-02 常州大学 一种2-硝基-4-甲氧基苯甲酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6136273A (ja) * 1984-07-26 1986-02-20 Mitsubishi Yuka Yakuhin Kk ２−フエニルアルキル−４（３ｈ）−キナゾリノン誘導体
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
US5783577A (en) * 1995-09-15 1998-07-21 Trega Biosciences, Inc. Synthesis of quinazolinone libraries and derivatives thereof
CN1116870C (zh) 1996-03-15 2003-08-06 萨默塞特药品有限公司 司立吉林在制备用于预防或治疗外周神经病的药物中的应用
JP4959049B2 (ja) * 1997-08-22 2012-06-20 アストラゼネカ・ユーケイ・リミテッド 血管新生阻害剤としてのオキシインドリルキナゾリン誘導体
US6890930B1 (en) * 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
WO2001034172A2 (en) 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
KR20050085587A (ko) 2005-08-29
GT200300284A (es) 2004-07-14
ES2270154T3 (es) 2007-04-01
AU2003293798B2 (en) 2009-01-15
AU2003293798A1 (en) 2004-07-09
PA8591901A1 (es) 2004-11-26
JP2006513177A (ja) 2006-04-20
MY141743A (en) 2010-06-30
PL377474A1 (pl) 2006-02-06
US20040142951A1 (en) 2004-07-22
KR100707532B1 (ko) 2007-04-12
RU2340604C2 (ru) 2008-12-10
PE20040911A1 (es) 2004-12-11
EP1572666B1 (en) 2006-08-09
DE60307512T2 (de) 2007-02-08
WO2004054985A1 (en) 2004-07-01
RU2005121908A (ru) 2006-01-27
CN100418954C (zh) 2008-09-17
CL2003002565A1 (es) 2005-01-07
EP1572666A1 (en) 2005-09-14
MXPA05006124A (es) 2005-08-16
JP4384053B2 (ja) 2009-12-16
TW200424180A (en) 2004-11-16
CN1720237A (zh) 2006-01-11
AR042362A1 (es) 2005-06-15
AU2003293798B8 (en) 2009-02-12
DE60307512D1 (de) 2006-09-21
BR0317282A (pt) 2005-11-08
CA2509633A1 (en) 2004-07-01
US7087612B2 (en) 2006-08-08
ATE335729T1 (de) 2006-09-15

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20150511