PL377474A1 - Pochodne 3H-chinazolin-4-onu - Google Patents

Pochodne 3H-chinazolin-4-onu

Info

Publication number
PL377474A1
PL377474A1 PL377474A PL37747403A PL377474A1 PL 377474 A1 PL377474 A1 PL 377474A1 PL 377474 A PL377474 A PL 377474A PL 37747403 A PL37747403 A PL 37747403A PL 377474 A1 PL377474 A1 PL 377474A1
Authority
PL
Poland
Prior art keywords
quinazolin
derivatives
Prior art date
Application number
PL377474A
Other languages
English (en)
Inventor
Sarmiento Rosa Maria Rodriguez
Andrew William Thomas
Rene Wyler
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL377474A1 publication Critical patent/PL377474A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL377474A 2002-12-13 2003-12-08 Pochodne 3H-chinazolin-4-onu PL377474A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02027700 2002-12-13

Publications (1)

Publication Number Publication Date
PL377474A1 true PL377474A1 (pl) 2006-02-06

Family

ID=32524001

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377474A PL377474A1 (pl) 2002-12-13 2003-12-08 Pochodne 3H-chinazolin-4-onu

Country Status (23)

Country Link
US (1) US7087612B2 (pl)
EP (1) EP1572666B1 (pl)
JP (1) JP4384053B2 (pl)
KR (1) KR100707532B1 (pl)
CN (1) CN100418954C (pl)
AR (1) AR042362A1 (pl)
AT (1) ATE335729T1 (pl)
AU (1) AU2003293798B8 (pl)
BR (1) BR0317282A (pl)
CA (1) CA2509633A1 (pl)
CL (1) CL2003002565A1 (pl)
DE (1) DE60307512T2 (pl)
ES (1) ES2270154T3 (pl)
GT (1) GT200300284A (pl)
MX (1) MXPA05006124A (pl)
MY (1) MY141743A (pl)
PA (1) PA8591901A1 (pl)
PE (1) PE20040911A1 (pl)
PL (1) PL377474A1 (pl)
RU (1) RU2340604C2 (pl)
TW (1) TW200424180A (pl)
UY (1) UY28120A1 (pl)
WO (1) WO2004054985A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006045010A2 (en) 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
KR20070094666A (ko) 2005-02-25 2007-09-20 에프. 호프만-라 로슈 아게 약제 물질 분산성이 향상된 정제
EP1909788A2 (en) 2005-07-29 2008-04-16 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
GB0525068D0 (en) * 2005-12-08 2006-01-18 Novartis Ag Organic compounds
JP4876690B2 (ja) * 2006-04-21 2012-02-15 三菱瓦斯化学株式会社 キナゾリン−4−オン誘導体の製造法
WO2008087736A1 (ja) * 2007-01-19 2008-07-24 Ube Industries, Ltd. アラルキルオキシ又はヘテロアラルキルオキシ基を有する芳香族アミンの製法
DK2118074T3 (en) 2007-02-01 2014-03-10 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
RU2520098C2 (ru) 2008-06-26 2014-06-20 Ресверлоджикс Корп. Способы получения производных хиназолинона
JP5635535B2 (ja) 2009-01-08 2014-12-03 レスバーロジックス コーポレイション 心血管疾患の予防および治療のための化合物
CA2992231C (en) 2009-03-18 2022-03-29 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
CN103945848B (zh) 2011-11-01 2016-09-07 雷斯韦洛吉克斯公司 被取代的喹唑啉酮的口服即释制剂
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
KR102662814B1 (ko) 2015-03-13 2024-05-03 리스버로직스 코퍼레이션 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법
CN106146410B (zh) * 2015-04-03 2018-10-12 中南大学 6-氨基-4(3h)-喹唑啉酮衍生物及其合成方法和用途
CN108191667B (zh) * 2018-01-04 2021-03-26 利尔化学股份有限公司 2-硝基-4-三氟甲基苯甲酸甲酯的制备方法
CN109553534A (zh) * 2018-11-27 2019-04-02 常州大学 一种2-硝基-4-甲氧基苯甲酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6136273A (ja) * 1984-07-26 1986-02-20 Mitsubishi Yuka Yakuhin Kk 2−フエニルアルキル−4(3h)−キナゾリノン誘導体
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
US5783577A (en) * 1995-09-15 1998-07-21 Trega Biosciences, Inc. Synthesis of quinazolinone libraries and derivatives thereof
CA2244253C (en) 1996-03-15 2002-11-12 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neuropathy by administering selegiline
WO1999010349A1 (en) * 1997-08-22 1999-03-04 Zeneca Limited Oxindolylquinazoline derivatives as angiogenesis inhibitors
US6890930B1 (en) * 1999-09-28 2005-05-10 3-Dimensional Pharmaceuticals, Inc. Quinazolinones
AU1359801A (en) 1999-11-05 2001-06-06 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
CL2003002565A1 (es) 2005-01-07
DE60307512T2 (de) 2007-02-08
MY141743A (en) 2010-06-30
AR042362A1 (es) 2005-06-15
WO2004054985A1 (en) 2004-07-01
RU2005121908A (ru) 2006-01-27
DE60307512D1 (de) 2006-09-21
PA8591901A1 (es) 2004-11-26
CN1720237A (zh) 2006-01-11
AU2003293798B2 (en) 2009-01-15
AU2003293798A1 (en) 2004-07-09
BR0317282A (pt) 2005-11-08
KR20050085587A (ko) 2005-08-29
EP1572666A1 (en) 2005-09-14
JP4384053B2 (ja) 2009-12-16
UY28120A1 (es) 2004-06-30
KR100707532B1 (ko) 2007-04-12
CA2509633A1 (en) 2004-07-01
ATE335729T1 (de) 2006-09-15
GT200300284A (es) 2004-07-14
US7087612B2 (en) 2006-08-08
PE20040911A1 (es) 2004-12-11
EP1572666B1 (en) 2006-08-09
RU2340604C2 (ru) 2008-12-10
JP2006513177A (ja) 2006-04-20
US20040142951A1 (en) 2004-07-22
AU2003293798B8 (en) 2009-02-12
TW200424180A (en) 2004-11-16
ES2270154T3 (es) 2007-04-01
CN100418954C (zh) 2008-09-17
MXPA05006124A (es) 2005-08-16

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)