UY27658A1 - Derivados de nicotinamida y una sal de tiotropio en combinación para el tratamiento de enfermedades - Google Patents
Derivados de nicotinamida y una sal de tiotropio en combinación para el tratamiento de enfermedadesInfo
- Publication number
- UY27658A1 UY27658A1 UY27658A UY27658A UY27658A1 UY 27658 A1 UY27658 A1 UY 27658A1 UY 27658 A UY27658 A UY 27658A UY 27658 A UY27658 A UY 27658A UY 27658 A1 UY27658 A1 UY 27658A1
- Authority
- UY
- Uruguay
- Prior art keywords
- combination
- diseases
- tiotropio
- salt
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
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- Health & Medical Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Urology & Nephrology (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0203193.8A GB0203193D0 (en) | 2002-02-11 | 2002-02-11 | Nicotinamide derivatives useful as pde4 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
UY27658A1 true UY27658A1 (es) | 2003-09-30 |
Family
ID=9930842
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27657A UY27657A1 (es) | 2002-02-11 | 2003-02-11 | Derivados de nicotinamida útiles como inhibidores de pde4 |
UY27658A UY27658A1 (es) | 2002-02-11 | 2003-02-11 | Derivados de nicotinamida y una sal de tiotropio en combinación para el tratamiento de enfermedades |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY27657A UY27657A1 (es) | 2002-02-11 | 2003-02-11 | Derivados de nicotinamida útiles como inhibidores de pde4 |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1476157A1 (fr) |
JP (1) | JP2005522449A (fr) |
AR (1) | AR038404A1 (fr) |
AU (2) | AU2003202116A1 (fr) |
BR (1) | BR0307574A (fr) |
CA (1) | CA2475708A1 (fr) |
GB (1) | GB0203193D0 (fr) |
GT (2) | GT200300033A (fr) |
HN (1) | HN2003000062A (fr) |
MX (1) | MXPA04007736A (fr) |
PA (2) | PA8566601A1 (fr) |
PE (2) | PE20030921A1 (fr) |
SV (1) | SV2004001481A (fr) |
TW (2) | TW200307545A (fr) |
UY (2) | UY27657A1 (fr) |
WO (2) | WO2003068232A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7102009B2 (en) | 2001-01-12 | 2006-09-05 | Amgen Inc. | Substituted amine derivatives and methods of use |
US7105682B2 (en) | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
US6878714B2 (en) | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
JP4583761B2 (ja) | 2002-02-11 | 2010-11-17 | ファイザー・インク | Pde4阻害剤として有用なニコチンアミド誘導体 |
US7307088B2 (en) | 2002-07-09 | 2007-12-11 | Amgen Inc. | Substituted anthranilic amide derivatives and methods of use |
US7153870B2 (en) | 2003-07-25 | 2006-12-26 | Pfizer Inc. | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317516D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317484D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
GB0317482D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
GB0317509D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
WO2005026132A1 (fr) * | 2003-09-17 | 2005-03-24 | Nippon Shinyaku Co., Ltd. | Inhibiteur de phosphodiesterase specifique d'amp cyclique |
WO2005042526A1 (fr) | 2003-11-03 | 2005-05-12 | Boehringer Ingelheim International Gmbh | Procede de production de sels de tiotropium, sels de tiotropium et formulations pharmaceutiques contenant ces sels |
CA2547394A1 (fr) * | 2004-01-09 | 2005-07-28 | Boehringer Ingelheim International Gmbh | Nouvelles compositions pharmaceutiques a base de derives de scopineester et de nicotinamide |
JP4874958B2 (ja) * | 2005-03-30 | 2012-02-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ピリジン誘導体を含有する抗真菌剤 |
EP1915152A2 (fr) * | 2005-08-08 | 2008-04-30 | Boehringer Ingelheim International GmbH | Methode de protection contre le risque de troubles cardiaques consistant a administrer des sels de tiotropium |
DE102005049429A1 (de) | 2005-10-15 | 2007-04-19 | Cognis Ip Management Gmbh | Verfahren zur Ausrüstung von Textilien |
EP1948167A1 (fr) * | 2005-10-19 | 2008-07-30 | Ranbaxy Laboratories, Ltd. | Compositions d'inhibiteurs de la phosphodiesterase de type iv |
US8247556B2 (en) | 2005-10-21 | 2012-08-21 | Amgen Inc. | Method for preparing 6-substituted-7-aza-indoles |
TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
DK2068873T3 (da) * | 2006-09-14 | 2012-02-27 | Bridge Biores Rights Jersey Ltd | Isoniazid-medieret heling af sår og ulcera |
US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
CN109020825B (zh) * | 2017-06-12 | 2021-03-19 | 重庆医科大学 | 抗流感病毒化合物及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3931041C2 (de) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
ID22781A (id) * | 1997-04-04 | 1999-12-09 | Pfizer Prod Inc | Turunan-turunan nikotinamida |
-
2002
- 2002-02-11 GB GBGB0203193.8A patent/GB0203193D0/en not_active Ceased
-
2003
- 2003-02-03 BR BR0307574-5A patent/BR0307574A/pt not_active IP Right Cessation
- 2003-02-03 WO PCT/IB2003/000377 patent/WO2003068232A1/fr not_active Application Discontinuation
- 2003-02-03 MX MXPA04007736A patent/MXPA04007736A/es active IP Right Grant
- 2003-02-03 AU AU2003202116A patent/AU2003202116A1/en not_active Abandoned
- 2003-02-03 JP JP2003567414A patent/JP2005522449A/ja not_active Withdrawn
- 2003-02-03 AU AU2003245812A patent/AU2003245812A1/en not_active Abandoned
- 2003-02-03 WO PCT/IB2003/000379 patent/WO2003068234A1/fr not_active Application Discontinuation
- 2003-02-03 EP EP03700974A patent/EP1476157A1/fr not_active Withdrawn
- 2003-02-03 CA CA002475708A patent/CA2475708A1/fr not_active Abandoned
- 2003-02-06 TW TW092102422A patent/TW200307545A/zh unknown
- 2003-02-06 TW TW092102415A patent/TW200304824A/zh unknown
- 2003-02-10 SV SV2003001481A patent/SV2004001481A/es not_active Application Discontinuation
- 2003-02-10 HN HN2003000062A patent/HN2003000062A/es unknown
- 2003-02-10 AR ARP030100406A patent/AR038404A1/es not_active Application Discontinuation
- 2003-02-10 GT GT200300033A patent/GT200300033A/es unknown
- 2003-02-10 GT GT200300034A patent/GT200300034A/es unknown
- 2003-02-11 PE PE2003000148A patent/PE20030921A1/es not_active Application Discontinuation
- 2003-02-11 UY UY27657A patent/UY27657A1/es not_active Application Discontinuation
- 2003-02-11 PA PA20038566601A patent/PA8566601A1/es unknown
- 2003-02-11 PA PA20038566501A patent/PA8566501A1/es unknown
- 2003-02-11 UY UY27658A patent/UY27658A1/es not_active Application Discontinuation
- 2003-02-11 PE PE2003000149A patent/PE20030860A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PA8566601A1 (es) | 2003-11-12 |
JP2005522449A (ja) | 2005-07-28 |
PA8566501A1 (es) | 2003-11-12 |
GT200300034A (es) | 2003-09-11 |
UY27657A1 (es) | 2003-09-30 |
EP1476157A1 (fr) | 2004-11-17 |
SV2004001481A (es) | 2004-05-07 |
AU2003202116A1 (en) | 2003-09-04 |
MXPA04007736A (es) | 2004-10-15 |
PE20030921A1 (es) | 2003-11-05 |
GT200300033A (es) | 2003-10-11 |
AR038404A1 (es) | 2005-01-12 |
WO2003068234A1 (fr) | 2003-08-21 |
BR0307574A (pt) | 2004-12-21 |
HN2003000062A (es) | 2003-09-24 |
TW200304824A (en) | 2003-10-16 |
WO2003068232A1 (fr) | 2003-08-21 |
CA2475708A1 (fr) | 2003-08-21 |
TW200307545A (en) | 2003-12-16 |
GB0203193D0 (en) | 2002-03-27 |
AU2003245812A1 (en) | 2003-09-04 |
PE20030860A1 (es) | 2003-10-25 |
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Legal Events
Date | Code | Title | Description |
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109 | Application deemed to be withdrawn |
Effective date: 20150126 |