UY27658A1 - NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASES - Google Patents
NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASESInfo
- Publication number
- UY27658A1 UY27658A1 UY27658A UY27658A UY27658A1 UY 27658 A1 UY27658 A1 UY 27658A1 UY 27658 A UY27658 A UY 27658A UY 27658 A UY27658 A UY 27658A UY 27658 A1 UY27658 A1 UY 27658A1
- Authority
- UY
- Uruguay
- Prior art keywords
- combination
- diseases
- tiotropio
- salt
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
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Abstract
La invención se refiere a una combinación de un derivado de nocotinamida y tiotropio o un derivado del mismo, a composiciones que los contienen y a los usos de dicha combinación. La combinación de acuerdo con la presente invención es útil en numerosas enfermedades, trastornos y afecciones, en particular enfermedades, trastornos y afecciones inflamatorias, alérgicas y respiratorias.The invention relates to a combination of a nocotinamide and tiotropium derivative or a derivative thereof, to compositions containing them and to the uses of said combination. The combination according to the present invention is useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0203193.8A GB0203193D0 (en) | 2002-02-11 | 2002-02-11 | Nicotinamide derivatives useful as pde4 inhibitors |
Publications (1)
Publication Number | Publication Date |
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UY27658A1 true UY27658A1 (en) | 2003-09-30 |
Family
ID=9930842
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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UY27657A UY27657A1 (en) | 2002-02-11 | 2003-02-11 | USEFUL NICOTINAMIDE DERIVATIVES AS PDE4 INHIBITORS |
UY27658A UY27658A1 (en) | 2002-02-11 | 2003-02-11 | NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASES |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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UY27657A UY27657A1 (en) | 2002-02-11 | 2003-02-11 | USEFUL NICOTINAMIDE DERIVATIVES AS PDE4 INHIBITORS |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1476157A1 (en) |
JP (1) | JP2005522449A (en) |
AR (1) | AR038404A1 (en) |
AU (2) | AU2003202116A1 (en) |
BR (1) | BR0307574A (en) |
CA (1) | CA2475708A1 (en) |
GB (1) | GB0203193D0 (en) |
GT (2) | GT200300033A (en) |
HN (1) | HN2003000062A (en) |
MX (1) | MXPA04007736A (en) |
PA (2) | PA8566601A1 (en) |
PE (2) | PE20030921A1 (en) |
SV (1) | SV2004001481A (en) |
TW (2) | TW200307545A (en) |
UY (2) | UY27657A1 (en) |
WO (2) | WO2003068232A1 (en) |
Families Citing this family (23)
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US7102009B2 (en) | 2001-01-12 | 2006-09-05 | Amgen Inc. | Substituted amine derivatives and methods of use |
US7105682B2 (en) | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
US6878714B2 (en) | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
JP4583761B2 (en) | 2002-02-11 | 2010-11-17 | ファイザー・インク | Nicotinamide derivatives useful as PDE4 inhibitors |
US7307088B2 (en) | 2002-07-09 | 2007-12-11 | Amgen Inc. | Substituted anthranilic amide derivatives and methods of use |
US7153870B2 (en) | 2003-07-25 | 2006-12-26 | Pfizer Inc. | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317516D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317484D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
GB0317482D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
GB0317509D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
WO2005026132A1 (en) * | 2003-09-17 | 2005-03-24 | Nippon Shinyaku Co., Ltd. | cAMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR |
WO2005042526A1 (en) | 2003-11-03 | 2005-05-12 | Boehringer Ingelheim International Gmbh | Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same |
CA2547394A1 (en) * | 2004-01-09 | 2005-07-28 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions based on a scopineester and nicotinamide derivatives |
JP4874958B2 (en) * | 2005-03-30 | 2012-02-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Antifungal agents containing pyridine derivatives |
EP1915152A2 (en) * | 2005-08-08 | 2008-04-30 | Boehringer Ingelheim International GmbH | Method for the protection against the risk of cardiac disorders comprising administration of tiotropium salts |
DE102005049429A1 (en) | 2005-10-15 | 2007-04-19 | Cognis Ip Management Gmbh | Process for finishing textiles |
EP1948167A1 (en) * | 2005-10-19 | 2008-07-30 | Ranbaxy Laboratories, Ltd. | Compositions of phosphodiesterase type iv inhibitors |
US8247556B2 (en) | 2005-10-21 | 2012-08-21 | Amgen Inc. | Method for preparing 6-substituted-7-aza-indoles |
TWI385169B (en) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
DK2068873T3 (en) * | 2006-09-14 | 2012-02-27 | Bridge Biores Rights Jersey Ltd | Isoniazid-mediated healing of wounds and ulcers |
US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
CN109020825B (en) * | 2017-06-12 | 2021-03-19 | 重庆医科大学 | Anti-influenza virus compound and preparation method thereof |
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DE3931041C2 (en) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them |
ID22781A (en) * | 1997-04-04 | 1999-12-09 | Pfizer Prod Inc | Nicotynamide derivatives |
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2002
- 2002-02-11 GB GBGB0203193.8A patent/GB0203193D0/en not_active Ceased
-
2003
- 2003-02-03 BR BR0307574-5A patent/BR0307574A/en not_active IP Right Cessation
- 2003-02-03 WO PCT/IB2003/000377 patent/WO2003068232A1/en not_active Application Discontinuation
- 2003-02-03 MX MXPA04007736A patent/MXPA04007736A/en active IP Right Grant
- 2003-02-03 AU AU2003202116A patent/AU2003202116A1/en not_active Abandoned
- 2003-02-03 JP JP2003567414A patent/JP2005522449A/en not_active Withdrawn
- 2003-02-03 AU AU2003245812A patent/AU2003245812A1/en not_active Abandoned
- 2003-02-03 WO PCT/IB2003/000379 patent/WO2003068234A1/en not_active Application Discontinuation
- 2003-02-03 EP EP03700974A patent/EP1476157A1/en not_active Withdrawn
- 2003-02-03 CA CA002475708A patent/CA2475708A1/en not_active Abandoned
- 2003-02-06 TW TW092102422A patent/TW200307545A/en unknown
- 2003-02-06 TW TW092102415A patent/TW200304824A/en unknown
- 2003-02-10 SV SV2003001481A patent/SV2004001481A/en not_active Application Discontinuation
- 2003-02-10 HN HN2003000062A patent/HN2003000062A/en unknown
- 2003-02-10 AR ARP030100406A patent/AR038404A1/en not_active Application Discontinuation
- 2003-02-10 GT GT200300033A patent/GT200300033A/en unknown
- 2003-02-10 GT GT200300034A patent/GT200300034A/en unknown
- 2003-02-11 PE PE2003000148A patent/PE20030921A1/en not_active Application Discontinuation
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- 2003-02-11 UY UY27658A patent/UY27658A1/en not_active Application Discontinuation
- 2003-02-11 PE PE2003000149A patent/PE20030860A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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PA8566601A1 (en) | 2003-11-12 |
JP2005522449A (en) | 2005-07-28 |
PA8566501A1 (en) | 2003-11-12 |
GT200300034A (en) | 2003-09-11 |
UY27657A1 (en) | 2003-09-30 |
EP1476157A1 (en) | 2004-11-17 |
SV2004001481A (en) | 2004-05-07 |
AU2003202116A1 (en) | 2003-09-04 |
MXPA04007736A (en) | 2004-10-15 |
PE20030921A1 (en) | 2003-11-05 |
GT200300033A (en) | 2003-10-11 |
AR038404A1 (en) | 2005-01-12 |
WO2003068234A1 (en) | 2003-08-21 |
BR0307574A (en) | 2004-12-21 |
HN2003000062A (en) | 2003-09-24 |
TW200304824A (en) | 2003-10-16 |
WO2003068232A1 (en) | 2003-08-21 |
CA2475708A1 (en) | 2003-08-21 |
TW200307545A (en) | 2003-12-16 |
GB0203193D0 (en) | 2002-03-27 |
AU2003245812A1 (en) | 2003-09-04 |
PE20030860A1 (en) | 2003-10-25 |
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