SV2004001481A - USEFUL NICOTINAMIDE DERIVATIVES AS PDE4 INHIBITORS "REF. PC22065A - Google Patents
USEFUL NICOTINAMIDE DERIVATIVES AS PDE4 INHIBITORS "REF. PC22065AInfo
- Publication number
- SV2004001481A SV2004001481A SV2003001481A SV2003001481A SV2004001481A SV 2004001481 A SV2004001481 A SV 2004001481A SV 2003001481 A SV2003001481 A SV 2003001481A SV 2003001481 A SV2003001481 A SV 2003001481A SV 2004001481 A SV2004001481 A SV 2004001481A
- Authority
- SV
- El Salvador
- Prior art keywords
- useful
- pc22065a
- ref
- derivatives
- pde4 inhibitors
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Abstract
DERIVADOS DE NICOTINAMIDA Y A PROCEDIMIENTOS PARA LA PREPARACION DE DICHOS DERIVADOS, A LOS INTERMEDIOS UTILIZADOS EN LA PREPARACION DE DICHOS DERIVADOS LOS DERIVADOS DE NICOTINAMIDA DE ACUERDO CON LA PRESENTE INVENCION SON UTILES EN NUMEROSAS ENFERMEDADES , TRASTORNOS Y AFECCIONES, EN PARTICULAR ENFERMEDADES , TRASTORNOS Y AFECCIONES INFLAMATORIAS, ALERGICAS Y RESPIRATORIAS , ASI COMO PARA CURAR HERIDAS.DERIVATIVES OF NICOTINAMIDE AND ALREADY PROCEDURES FOR THE PREPARATION OF SUCH DERIVATIVES, TO THE INTERMEDIATES USED IN THE PREPARATION OF SUCH DERIVATIVES THE DERIVATIVES OF NICOTINAMIDE IN ACCORDANCE WITH THE PRESENT INVENTION ARE USEFUL IN NUMEROUS DISEASES, DISORDERS AND DISCUSSIONS , ALLERGIC AND RESPIRATORY, AS WELL TO HEAL WOUNDS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0203193.8A GB0203193D0 (en) | 2002-02-11 | 2002-02-11 | Nicotinamide derivatives useful as pde4 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2004001481A true SV2004001481A (en) | 2004-05-07 |
Family
ID=9930842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SV2003001481A SV2004001481A (en) | 2002-02-11 | 2003-02-10 | USEFUL NICOTINAMIDE DERIVATIVES AS PDE4 INHIBITORS "REF. PC22065A |
Country Status (16)
Country | Link |
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EP (1) | EP1476157A1 (en) |
JP (1) | JP2005522449A (en) |
AR (1) | AR038404A1 (en) |
AU (2) | AU2003245812A1 (en) |
BR (1) | BR0307574A (en) |
CA (1) | CA2475708A1 (en) |
GB (1) | GB0203193D0 (en) |
GT (2) | GT200300034A (en) |
HN (1) | HN2003000062A (en) |
MX (1) | MXPA04007736A (en) |
PA (2) | PA8566501A1 (en) |
PE (2) | PE20030921A1 (en) |
SV (1) | SV2004001481A (en) |
TW (2) | TW200304824A (en) |
UY (2) | UY27658A1 (en) |
WO (2) | WO2003068234A1 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
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US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
US7102009B2 (en) | 2001-01-12 | 2006-09-05 | Amgen Inc. | Substituted amine derivatives and methods of use |
US6878714B2 (en) | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
US7105682B2 (en) | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
DE60317466T2 (en) | 2002-02-11 | 2008-03-06 | Pfizer Inc. | Nicotinamide derivatives which can be used as PDE4 inhibitors |
US7307088B2 (en) | 2002-07-09 | 2007-12-11 | Amgen Inc. | Substituted anthranilic amide derivatives and methods of use |
GB0317509D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
US7153870B2 (en) | 2003-07-25 | 2006-12-26 | Pfizer Inc. | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317482D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
GB0317516D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0317484D0 (en) * | 2003-07-25 | 2003-08-27 | Pfizer Ltd | Nicotinamide derivatives useful as pde4 inhibitors |
WO2005026132A1 (en) * | 2003-09-17 | 2005-03-24 | Nippon Shinyaku Co., Ltd. | cAMP-SPECIFIC PHOSPHODIESTERASE INHIBITOR |
PT1682541E (en) | 2003-11-03 | 2010-04-14 | Boehringer Ingelheim Int | Method for producing tiotropium salts |
WO2005067929A1 (en) * | 2004-01-09 | 2005-07-28 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions based on a scopineester and nicotinamide derivatives |
US7829585B2 (en) * | 2005-03-30 | 2010-11-09 | Eisai R&D Management Co., Ltd. | Antifungal agent containing pyridine derivative |
CA2617101A1 (en) * | 2005-08-08 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Method for the protection against the risk of cardiac disorders comprising administration of tiotropium salts |
DE102005049429A1 (en) | 2005-10-15 | 2007-04-19 | Cognis Ip Management Gmbh | Process for finishing textiles |
BRPI0617673C1 (en) * | 2005-10-19 | 2012-05-22 | Ranbaxy Lab Ltd | phosphodiesterase type iv inhibitor compositions |
US8247556B2 (en) | 2005-10-21 | 2012-08-21 | Amgen Inc. | Method for preparing 6-substituted-7-aza-indoles |
TWI385169B (en) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
EP2068873B1 (en) * | 2006-09-14 | 2011-11-09 | Bridge BioResearch Rights (Jersey) Limited | Isoniazid mediated healing of wounds and ulcers |
US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
CN109020825B (en) * | 2017-06-12 | 2021-03-19 | 重庆医科大学 | Anti-influenza virus compound and preparation method thereof |
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DE3931041C2 (en) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them |
EA003528B1 (en) * | 1997-04-04 | 2003-06-26 | Пфайзер Продактс Инк. | Nicotinamide derivatives, use thereof, pharmaceutical composition, method of treatment and method for selective inhibition of pde4 d isoenzymes |
-
2002
- 2002-02-11 GB GBGB0203193.8A patent/GB0203193D0/en not_active Ceased
-
2003
- 2003-02-03 AU AU2003245812A patent/AU2003245812A1/en not_active Abandoned
- 2003-02-03 EP EP03700974A patent/EP1476157A1/en not_active Withdrawn
- 2003-02-03 CA CA002475708A patent/CA2475708A1/en not_active Abandoned
- 2003-02-03 AU AU2003202116A patent/AU2003202116A1/en not_active Abandoned
- 2003-02-03 MX MXPA04007736A patent/MXPA04007736A/en active IP Right Grant
- 2003-02-03 WO PCT/IB2003/000379 patent/WO2003068234A1/en not_active Application Discontinuation
- 2003-02-03 JP JP2003567414A patent/JP2005522449A/en not_active Withdrawn
- 2003-02-03 WO PCT/IB2003/000377 patent/WO2003068232A1/en not_active Application Discontinuation
- 2003-02-03 BR BR0307574-5A patent/BR0307574A/en not_active IP Right Cessation
- 2003-02-06 TW TW092102415A patent/TW200304824A/en unknown
- 2003-02-06 TW TW092102422A patent/TW200307545A/en unknown
- 2003-02-10 HN HN2003000062A patent/HN2003000062A/en unknown
- 2003-02-10 AR ARP030100406A patent/AR038404A1/en not_active Application Discontinuation
- 2003-02-10 SV SV2003001481A patent/SV2004001481A/en not_active Application Discontinuation
- 2003-02-10 GT GT200300034A patent/GT200300034A/en unknown
- 2003-02-10 GT GT200300033A patent/GT200300033A/en unknown
- 2003-02-11 PA PA20038566501A patent/PA8566501A1/en unknown
- 2003-02-11 PE PE2003000148A patent/PE20030921A1/en not_active Application Discontinuation
- 2003-02-11 PE PE2003000149A patent/PE20030860A1/en not_active Application Discontinuation
- 2003-02-11 UY UY27658A patent/UY27658A1/en not_active Application Discontinuation
- 2003-02-11 UY UY27657A patent/UY27657A1/en not_active Application Discontinuation
- 2003-02-11 PA PA20038566601A patent/PA8566601A1/en unknown
Also Published As
Publication number | Publication date |
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WO2003068232A1 (en) | 2003-08-21 |
AU2003245812A1 (en) | 2003-09-04 |
CA2475708A1 (en) | 2003-08-21 |
HN2003000062A (en) | 2003-09-24 |
MXPA04007736A (en) | 2004-10-15 |
PE20030921A1 (en) | 2003-11-05 |
BR0307574A (en) | 2004-12-21 |
JP2005522449A (en) | 2005-07-28 |
PA8566601A1 (en) | 2003-11-12 |
PA8566501A1 (en) | 2003-11-12 |
WO2003068234A1 (en) | 2003-08-21 |
GT200300034A (en) | 2003-09-11 |
AU2003202116A1 (en) | 2003-09-04 |
EP1476157A1 (en) | 2004-11-17 |
TW200304824A (en) | 2003-10-16 |
UY27657A1 (en) | 2003-09-30 |
GB0203193D0 (en) | 2002-03-27 |
GT200300033A (en) | 2003-10-11 |
TW200307545A (en) | 2003-12-16 |
AR038404A1 (en) | 2005-01-12 |
UY27658A1 (en) | 2003-09-30 |
PE20030860A1 (en) | 2003-10-25 |
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