PA8566501A1 - NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASES - Google Patents

NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASES

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Publication number
PA8566501A1
PA8566501A1 PA20038566501A PA8566501A PA8566501A1 PA 8566501 A1 PA8566501 A1 PA 8566501A1 PA 20038566501 A PA20038566501 A PA 20038566501A PA 8566501 A PA8566501 A PA 8566501A PA 8566501 A1 PA8566501 A1 PA 8566501A1
Authority
PA
Panama
Prior art keywords
combination
diseases
tiotropio
salt
treatment
Prior art date
Application number
PA20038566501A
Other languages
Spanish (es)
Inventor
Thomas Victor Magee
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8566501A1 publication Critical patent/PA8566501A1/en

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Abstract

LA INVENCION SE REFIERE A UNA COMBINACION DE UN DERIVADO DE NICOTINAMIDA Y TIOTROPIO O UN DERIVADO DEL MISMO, A COMPOSICIONES QUE LOS CONTIENEN Y A LOS USOS DE DICHA COMBINACION. LA COMBINACION DE ACUERDO CON LA PRESENTE INVENCION ES UTIL EN NUMEROSAS ENFERMEDADES, TRASTORNOS Y AFECCIONES EN PARTICULAR ENFERMEDADES, TRASTORNOS Y AFECCIONES INFLAMATORIAS, ALERGICAS Y RESPIRATORIAS.THE INVENTION REFERS TO A COMBINATION OF A NICOTINAMIDE AND TIOTROPIO DERIVATIVE OR A DERIVATIVE OF THE SAME, COMPOSITIONS THAT CONTAIN THEM AND THE USES OF SUCH COMBINATION. THE COMBINATION IN ACCORDANCE WITH THE PRESENT INVENTION IS USEFUL IN NUMEROUS DISEASES, DISORDERS AND AFFECTIONS IN PARTICULAR DISEASES, DISORDERS AND INFLAMMATORY, ALLERGIC AND RESPIRATORY AFFECTIONS.

PA20038566501A 2002-02-11 2003-02-11 NICOTINAMIDE DERIVATIVES AND A COMBINATION TIOTROPIO SALT FOR THE TREATMENT OF DISEASES PA8566501A1 (en)

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CA2475708A1 (en) 2003-08-21
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BR0307574A (en) 2004-12-21
AU2003202116A1 (en) 2003-09-04
UY27657A1 (en) 2003-09-30
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TW200304824A (en) 2003-10-16
TW200307545A (en) 2003-12-16

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