UY26208A1 - Antagonistas de los receptores de la il-8. - Google Patents
Antagonistas de los receptores de la il-8.Info
- Publication number
- UY26208A1 UY26208A1 UY26208A UY26208A UY26208A1 UY 26208 A1 UY26208 A1 UY 26208A1 UY 26208 A UY26208 A UY 26208A UY 26208 A UY26208 A UY 26208A UY 26208 A1 UY26208 A1 UY 26208A1
- Authority
- UY
- Uruguay
- Prior art keywords
- antagonists
- receivers
- chemokine
- interleukin
- compositions
- Prior art date
Links
- 108090001007 Interleukin-8 Proteins 0.000 title abstract 3
- 239000005557 antagonist Substances 0.000 title 1
- 102000004890 Interleukin-8 Human genes 0.000 abstract 2
- XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 abstract 2
- 229940096397 interleukin-8 Drugs 0.000 abstract 2
- 102000019034 Chemokines Human genes 0.000 abstract 1
- 108010012236 Chemokines Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Esta invención se refiere a nuevos compuestos de la fórmula (I), y a composiciones de los mismos, útiles en el tratamiento de enfermedades mediadas por la quimioquina, interleuquina-8 (IL-8).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14002599P | 1999-06-16 | 1999-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY26208A1 true UY26208A1 (es) | 2000-12-29 |
Family
ID=22489384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY26208A UY26208A1 (es) | 1999-06-16 | 2000-06-14 | Antagonistas de los receptores de la il-8. |
Country Status (6)
| Country | Link |
|---|---|
| AU (1) | AU5622400A (es) |
| CO (1) | CO5190720A1 (es) |
| EC (1) | ECSP003529A (es) |
| PE (1) | PE20010320A1 (es) |
| UY (1) | UY26208A1 (es) |
| WO (1) | WO2000076508A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007022964A2 (de) | 2005-08-24 | 2007-03-01 | Abbott Gmbh & Co. Kg | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684032A (en) * | 1994-12-13 | 1997-11-04 | Smithkline Beecham Corporation | Compounds |
| US5780483A (en) * | 1995-02-17 | 1998-07-14 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| EP1021181A4 (en) * | 1996-03-28 | 2002-06-26 | Smithkline Beecham Corp | INDOLCARBOXYLIC ACIDS AS CHEMOKIN INHIBITORS |
-
2000
- 2000-06-14 UY UY26208A patent/UY26208A1/es not_active Application Discontinuation
- 2000-06-14 CO CO00044292A patent/CO5190720A1/es unknown
- 2000-06-14 PE PE2000000592A patent/PE20010320A1/es not_active Application Discontinuation
- 2000-06-14 EC EC2000003529A patent/ECSP003529A/es unknown
- 2000-06-16 WO PCT/US2000/016756 patent/WO2000076508A1/en active Application Filing
- 2000-06-16 AU AU56224/00A patent/AU5622400A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU5622400A (en) | 2001-01-02 |
| CO5190720A1 (es) | 2002-08-29 |
| ECSP003529A (es) | 2002-01-25 |
| PE20010320A1 (es) | 2001-05-18 |
| WO2000076508A1 (en) | 2000-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20100520 |