UY25441A1 - Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral. - Google Patents
Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral.Info
- Publication number
- UY25441A1 UY25441A1 UY25441A UY25441A UY25441A1 UY 25441 A1 UY25441 A1 UY 25441A1 UY 25441 A UY25441 A UY 25441A UY 25441 A UY25441 A UY 25441A UY 25441 A1 UY25441 A1 UY 25441A1
- Authority
- UY
- Uruguay
- Prior art keywords
- salt
- meloxicam
- procedure
- preparation
- oral application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Procedimiento para la preparación de una forma medicamentosa sólida de Meloxicam, que pertenece a los fármacos no esteroides anti-inflamatorios, aplicable por vía oral, que posee un corto tiempo de descomposición y de la que se libera y absorbe rápidamente el principio activo, para la terapia de dolores. Este procedimiento está caracterizado porque una sal de Meloxicam, eventualmente pulverizada, de una base inorgánica u orgánica, preferiblemente la sal de sodio, potasio o amonio, la sal de Meglumina, la sal Tris o la sal de un aminoácido de carácter básico, se mezcla íntimamente con coadyuvantes y/o sustancias de soporte pulverizados adecuados y, sin granulación del polvo antes del prensado, se prensa directamente en tabletas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98105569A EP0945134A1 (de) | 1998-03-27 | 1998-03-27 | Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY25441A1 true UY25441A1 (es) | 1999-11-17 |
Family
ID=8231652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY25441A UY25441A1 (es) | 1998-03-27 | 1999-03-24 | Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6869948B1 (es) |
| EP (2) | EP0945134A1 (es) |
| JP (1) | JP3639532B2 (es) |
| KR (1) | KR100589299B1 (es) |
| CN (1) | CN1163231C (es) |
| AR (1) | AR016197A1 (es) |
| AT (1) | ATE254920T1 (es) |
| AU (1) | AU762322C (es) |
| BR (1) | BR9909192A (es) |
| CA (1) | CA2326517C (es) |
| DE (1) | DE59907871D1 (es) |
| DK (1) | DK1083902T3 (es) |
| ES (1) | ES2212547T3 (es) |
| HK (1) | HK1034183A1 (es) |
| HU (1) | HUP0101246A3 (es) |
| IL (2) | IL137652A0 (es) |
| NO (1) | NO326852B1 (es) |
| NZ (1) | NZ507382A (es) |
| PL (1) | PL192967B1 (es) |
| PT (1) | PT1083902E (es) |
| TR (1) | TR200002786T2 (es) |
| TW (1) | TWI236914B (es) |
| UY (1) | UY25441A1 (es) |
| WO (1) | WO1999049867A1 (es) |
| ZA (1) | ZA200004178B (es) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL197077B1 (pl) | 1998-12-01 | 2008-02-29 | Reddys Lab Inc Dr | Kompozycja farmaceutyczna zawierająca 5-[[4-[3-metylo-4-okso-3,4-dihydro-2-chinazolinylo]metoksy]fenylometylo]-tiazolidyno-2,4-dion lub jego sól dopuszczalną do stosowania w farmacji i sposób jej wytwarzania |
| AU1548001A (en) | 1999-11-24 | 2001-06-04 | Wakamoto Pharmaceutical Co., Ltd. | Ophthalmic aqueous preparation |
| JP2004506609A (ja) | 2000-05-26 | 2004-03-04 | ノボ ノルディスク アクティーゼルスカブ | 新たなる医薬組成物及びその調製の為の方法 |
| AU2000249111A1 (en) * | 2000-05-30 | 2001-12-11 | Dr. Reddy's Research Foundation | New pharmaceutical composition and the process for its preparation |
| DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
| US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| US7120656B1 (en) | 2000-10-04 | 2006-10-10 | Marvell International Ltd. | Movable tap finite impulse response filter |
| PL363771A1 (en) * | 2001-02-27 | 2004-11-29 | Ranbaxy Laboratories Limited | Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors |
| EP1250921A1 (en) * | 2001-04-21 | 2002-10-23 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Fast disintegrating meloxicam tablet |
| DE10161077A1 (de) * | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| EP1348436A1 (en) * | 2002-03-30 | 2003-10-01 | Boehringer Ingelheim International GmbH | Meloxicam suppositories |
| GB0209257D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| DE10232113A1 (de) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| DE10250081A1 (de) * | 2002-10-25 | 2004-05-13 | Boehringer Ingelheim Vetmedica Gmbh | Wasserlösliche Meloxicam Granulate |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| SI1685829T1 (sl) | 2002-11-22 | 2008-08-31 | Gruenenthal Gmbh | Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine |
| US8512727B2 (en) * | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
| US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| US20040225018A1 (en) * | 2003-03-17 | 2004-11-11 | Japan Tobacco Inc. | Pharmaceutical compositions of CETP inhibitors |
| KR100620239B1 (ko) * | 2004-01-05 | 2006-09-13 | 신일제약주식회사 | 용해도 및 안정성이 향상된 경구투여용 멜록시캄 고형제조성물 |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| DE102004021281A1 (de) * | 2004-04-29 | 2005-11-24 | Boehringer Ingelheim Vetmedica Gmbh | Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin |
| DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
| US20060025408A1 (en) * | 2004-08-02 | 2006-02-02 | Sundaram Venkataraman | Process for the preparation of crystalline form-1 of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide |
| LT3056492T (lt) | 2004-10-08 | 2022-01-25 | Abbvie Inc. | Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos |
| HU227359B1 (en) * | 2004-12-18 | 2011-04-28 | Egis Gyogyszergyar Nyilvanosan Mikodi Ruszvunytarsasag | Process for producing meloxicam and meloxicam potassium salt of high purity |
| EP1824493B1 (en) | 2004-12-06 | 2008-08-13 | Janssen Pharmaceutica N.V. | Oral suspension comprising meloxicam |
| JP5577021B2 (ja) | 2005-02-17 | 2014-08-20 | アボット・ラボラトリーズ | 動物における障害を治療および予防するための薬剤組成物の経粘膜投与 |
| WO2007011349A1 (en) * | 2005-07-15 | 2007-01-25 | Teva Pharmaceutical Industries Ltd. | Novel granulation process and granulate produced therefrom |
| WO2007039417A1 (en) * | 2005-09-30 | 2007-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical preparation containing meloxicam |
| US7572641B2 (en) | 2005-11-22 | 2009-08-11 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical compositions comprising meloxicam and methods of their preparation |
| EP1965774A2 (en) * | 2005-12-30 | 2008-09-10 | Cogentus Pharmaceuticals, Inc. | Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors |
| KR100791160B1 (ko) * | 2006-05-30 | 2008-01-02 | 조선대학교산학협력단 | 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물 |
| US20070281927A1 (en) * | 2006-06-06 | 2007-12-06 | Shanthakumar Tyavanagimatt | Anti-inflammatory and analgesic compositions and related methods |
| US8124603B2 (en) * | 2008-01-22 | 2012-02-28 | Thar Pharmaceuticals | In vivo studies of crystalline forms of meloxicam |
| TR200809200A1 (tr) | 2008-12-01 | 2009-12-21 | Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� | Meloksikam içeren farmasötik formülasyonlar |
| CN102647971B (zh) | 2009-10-12 | 2016-03-16 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 用于包含美洛昔康的组合物的容器 |
| WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| US8791105B2 (en) | 2010-07-14 | 2014-07-29 | Kansas State University Research Foundation | Methods for alleviating chronic pain and improving performance of cattle undergoing dehorning or castration |
| US20170281640A1 (en) * | 2016-04-04 | 2017-10-05 | Productos Maver, S.A. De C.V. | Pharmaceutical Compositions Containing a Muscle Relaxant and a Nonsteroidal Anti-Inflammatory Drugs (NSAID) |
| CN113614077A (zh) * | 2018-11-05 | 2021-11-05 | 迈兰实验室有限公司 | 美洛昔康共晶 |
| WO2020219406A1 (en) | 2019-04-22 | 2020-10-29 | Mylan Specialty L.P. | Meloxicam co-crystal compositions |
| JP2023547736A (ja) | 2020-11-06 | 2023-11-13 | マイラン ラボラトリーズ エルティーディー | メロキシカム含有医薬組成物 |
| CN112587497A (zh) * | 2020-12-25 | 2021-04-02 | 苏州中化药品工业有限公司 | 一种美洛昔康混悬液胶囊剂及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2756113A1 (de) * | 1977-12-16 | 1979-06-21 | Thomae Gmbh Dr K | Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| IT1207994B (it) * | 1986-01-03 | 1989-06-01 | Therapicon Srl | Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche. |
| AU730495B2 (en) * | 1995-11-13 | 2001-03-08 | North West University | Administration media for analgesic, antiinflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs |
| WO1999009988A1 (en) * | 1997-08-27 | 1999-03-04 | Hexal Ag | New pharmaceutical compositions of meloxicam with improved solubility and bioavailability |
-
1998
- 1998-03-27 EP EP98105569A patent/EP0945134A1/de not_active Withdrawn
-
1999
- 1999-03-04 TW TW088103316A patent/TWI236914B/zh not_active IP Right Cessation
- 1999-03-23 IL IL13765299A patent/IL137652A0/xx active IP Right Grant
- 1999-03-23 KR KR1020007010703A patent/KR100589299B1/ko not_active IP Right Cessation
- 1999-03-23 PL PL342988A patent/PL192967B1/pl not_active IP Right Cessation
- 1999-03-23 NZ NZ507382A patent/NZ507382A/en unknown
- 1999-03-23 ES ES99915690T patent/ES2212547T3/es not_active Expired - Lifetime
- 1999-03-23 PT PT99915690T patent/PT1083902E/pt unknown
- 1999-03-23 WO PCT/EP1999/001949 patent/WO1999049867A1/de active IP Right Grant
- 1999-03-23 AU AU34171/99A patent/AU762322C/en not_active Ceased
- 1999-03-23 DK DK99915690T patent/DK1083902T3/da active
- 1999-03-23 TR TR2000/02786T patent/TR200002786T2/xx unknown
- 1999-03-23 JP JP2000540830A patent/JP3639532B2/ja not_active Expired - Lifetime
- 1999-03-23 DE DE59907871T patent/DE59907871D1/de not_active Expired - Lifetime
- 1999-03-23 AT AT99915690T patent/ATE254920T1/de active
- 1999-03-23 HU HU0101246A patent/HUP0101246A3/hu unknown
- 1999-03-23 EP EP99915690A patent/EP1083902B1/de not_active Expired - Lifetime
- 1999-03-23 BR BR9909192-5A patent/BR9909192A/pt not_active Application Discontinuation
- 1999-03-23 CA CA002326517A patent/CA2326517C/en not_active Expired - Lifetime
- 1999-03-23 CN CNB998044687A patent/CN1163231C/zh not_active Expired - Fee Related
- 1999-03-24 UY UY25441A patent/UY25441A1/es not_active Application Discontinuation
- 1999-03-26 AR ARP990101339A patent/AR016197A1/es not_active Suspension/Interruption
- 1999-03-26 US US09/277,049 patent/US6869948B1/en not_active Expired - Lifetime
-
2000
- 2000-08-01 IL IL137652A patent/IL137652A/en not_active IP Right Cessation
- 2000-08-16 ZA ZA200004178A patent/ZA200004178B/en unknown
- 2000-09-26 NO NO20004823A patent/NO326852B1/no not_active IP Right Cessation
-
2001
- 2001-07-04 HK HK01104588A patent/HK1034183A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20110817 |