UY25441A1 - Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral. - Google Patents

Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral.

Info

Publication number
UY25441A1
UY25441A1 UY25441A UY25441A UY25441A1 UY 25441 A1 UY25441 A1 UY 25441A1 UY 25441 A UY25441 A UY 25441A UY 25441 A UY25441 A UY 25441A UY 25441 A1 UY25441 A1 UY 25441A1
Authority
UY
Uruguay
Prior art keywords
salt
meloxicam
procedure
preparation
oral application
Prior art date
Application number
UY25441A
Other languages
English (en)
Inventor
Thomas Bock Dr
Sägmüller Paul
Peter Sieger Dr
Dietrich Türck Dr
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY25441A1 publication Critical patent/UY25441A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para la preparación de una forma medicamentosa sólida de Meloxicam, que pertenece a los fármacos no esteroides anti-inflamatorios, aplicable por vía oral, que posee un corto tiempo de descomposición y de la que se libera y absorbe rápidamente el principio activo, para la terapia de dolores. Este procedimiento está caracterizado porque una sal de Meloxicam, eventualmente pulverizada, de una base inorgánica u orgánica, preferiblemente la sal de sodio, potasio o amonio, la sal de Meglumina, la sal Tris o la sal de un aminoácido de carácter básico, se mezcla íntimamente con coadyuvantes y/o sustancias de soporte pulverizados adecuados y, sin granulación del polvo antes del prensado, se prensa directamente en tabletas.
UY25441A 1998-03-27 1999-03-24 Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral. UY25441A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98105569A EP0945134A1 (de) 1998-03-27 1998-03-27 Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation

Publications (1)

Publication Number Publication Date
UY25441A1 true UY25441A1 (es) 1999-11-17

Family

ID=8231652

Family Applications (1)

Application Number Title Priority Date Filing Date
UY25441A UY25441A1 (es) 1998-03-27 1999-03-24 Procedimiento para la preparacion de formas galenicas de meloxicam para la aplicacion oral.

Country Status (25)

Country Link
US (1) US6869948B1 (es)
EP (2) EP0945134A1 (es)
JP (1) JP3639532B2 (es)
KR (1) KR100589299B1 (es)
CN (1) CN1163231C (es)
AR (1) AR016197A1 (es)
AT (1) ATE254920T1 (es)
AU (1) AU762322C (es)
BR (1) BR9909192A (es)
CA (1) CA2326517C (es)
DE (1) DE59907871D1 (es)
DK (1) DK1083902T3 (es)
ES (1) ES2212547T3 (es)
HK (1) HK1034183A1 (es)
HU (1) HUP0101246A3 (es)
IL (2) IL137652A0 (es)
NO (1) NO326852B1 (es)
NZ (1) NZ507382A (es)
PL (1) PL192967B1 (es)
PT (1) PT1083902E (es)
TR (1) TR200002786T2 (es)
TW (1) TWI236914B (es)
UY (1) UY25441A1 (es)
WO (1) WO1999049867A1 (es)
ZA (1) ZA200004178B (es)

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AU1548001A (en) 1999-11-24 2001-06-04 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
JP2004506609A (ja) 2000-05-26 2004-03-04 ノボ ノルディスク アクティーゼルスカブ 新たなる医薬組成物及びその調製の為の方法
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
US7120656B1 (en) 2000-10-04 2006-10-10 Marvell International Ltd. Movable tap finite impulse response filter
PL363771A1 (en) * 2001-02-27 2004-11-29 Ranbaxy Laboratories Limited Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors
EP1250921A1 (en) * 2001-04-21 2002-10-23 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Fast disintegrating meloxicam tablet
DE10161077A1 (de) * 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (en) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Meloxicam suppositories
GB0209257D0 (en) * 2002-04-23 2002-06-05 Novartis Ag Organic compounds
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
SI1685829T1 (sl) 2002-11-22 2008-08-31 Gruenenthal Gmbh Uporaba (1RS,3RS,6RS)-6-dimetilaminometil-1- (3-metoksi-fenil)-cikloheksan-1, 3-diola za zdravljenje vnetne bolečine
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
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DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
US20060025408A1 (en) * 2004-08-02 2006-02-02 Sundaram Venkataraman Process for the preparation of crystalline form-1 of 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
LT3056492T (lt) 2004-10-08 2022-01-25 Abbvie Inc. Meglumino druska ir atitinkamos vaisto (delafloksacino) kristalinės formos
HU227359B1 (en) * 2004-12-18 2011-04-28 Egis Gyogyszergyar Nyilvanosan Mikodi Ruszvunytarsasag Process for producing meloxicam and meloxicam potassium salt of high purity
EP1824493B1 (en) 2004-12-06 2008-08-13 Janssen Pharmaceutica N.V. Oral suspension comprising meloxicam
JP5577021B2 (ja) 2005-02-17 2014-08-20 アボット・ラボラトリーズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与
WO2007011349A1 (en) * 2005-07-15 2007-01-25 Teva Pharmaceutical Industries Ltd. Novel granulation process and granulate produced therefrom
WO2007039417A1 (en) * 2005-09-30 2007-04-12 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical preparation containing meloxicam
US7572641B2 (en) 2005-11-22 2009-08-11 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions comprising meloxicam and methods of their preparation
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US20070281927A1 (en) * 2006-06-06 2007-12-06 Shanthakumar Tyavanagimatt Anti-inflammatory and analgesic compositions and related methods
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CN102647971B (zh) 2009-10-12 2016-03-16 贝林格尔.英格海姆维特梅迪卡有限公司 用于包含美洛昔康的组合物的容器
WO2011107150A1 (en) 2010-03-03 2011-09-09 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
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Also Published As

Publication number Publication date
BR9909192A (pt) 2000-12-05
NZ507382A (en) 2003-08-29
PL342988A1 (en) 2001-07-16
CN1163231C (zh) 2004-08-25
EP0945134A1 (de) 1999-09-29
TR200002786T2 (tr) 2001-01-22
KR100589299B1 (ko) 2006-06-14
KR20010034698A (ko) 2001-04-25
NO20004823D0 (no) 2000-09-26
AU762322C (en) 2004-02-12
NO20004823L (no) 2000-11-22
AU3417199A (en) 1999-10-18
AR016197A1 (es) 2001-06-20
ZA200004178B (en) 2002-04-24
HK1034183A1 (en) 2001-10-19
EP1083902A1 (de) 2001-03-21
JP2002509886A (ja) 2002-04-02
CA2326517C (en) 2008-06-10
CA2326517A1 (en) 1999-10-07
IL137652A0 (en) 2001-10-31
ATE254920T1 (de) 2003-12-15
AU762322B2 (en) 2003-06-26
PT1083902E (pt) 2004-04-30
IL137652A (en) 2006-10-05
DK1083902T3 (da) 2004-03-29
HUP0101246A3 (en) 2002-08-28
TWI236914B (en) 2005-08-01
DE59907871D1 (de) 2004-01-08
HUP0101246A2 (hu) 2002-05-29
ES2212547T3 (es) 2004-07-16
CN1295478A (zh) 2001-05-16
EP1083902B1 (de) 2003-11-26
WO1999049867A1 (de) 1999-10-07
US6869948B1 (en) 2005-03-22
PL192967B1 (pl) 2006-12-29
JP3639532B2 (ja) 2005-04-20
NO326852B1 (no) 2009-03-02

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