US8453687B2 - Device for metering a powdered product - Google Patents

Device for metering a powdered product Download PDF

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Publication number
US8453687B2
US8453687B2 US12/668,605 US66860508A US8453687B2 US 8453687 B2 US8453687 B2 US 8453687B2 US 66860508 A US66860508 A US 66860508A US 8453687 B2 US8453687 B2 US 8453687B2
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United States
Prior art keywords
transfer
transfer plunger
plunger
drive unit
movement system
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US12/668,605
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US20100200112A1 (en
Inventor
Ralf Schmied
Jens Schlipf
Walter Boehringer
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Syntegon Technology GmbH
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Robert Bosch GmbH
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Assigned to ROBERT BOSCH GMBH reassignment ROBERT BOSCH GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BOEHRINGER, WALTER, SCHLIPF, JENS, SCHMIED, RALF
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Assigned to ROBERT BOSCH PACKAGING TECHNOLOGY GMBH reassignment ROBERT BOSCH PACKAGING TECHNOLOGY GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ROBERT BOSCH GMBH
Assigned to SYNTEGON TECHNOLOGY GMBH reassignment SYNTEGON TECHNOLOGY GMBH CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: ROBERT BOSCH PACKAGING TECHNOLOGY GMBH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations

Definitions

  • the invention is based on a device for metering a powdered product.
  • German Patent Disclosure DE 102 11 118 A1 one such device is already known, which has a product container with bores embodied in its bottom. The bores cooperate with stuffing plungers and transfer plungers. A stuffing ring that serves as a counterholder to the stuffing plungers is disposed below the bottom. To avoid powder losses, it is provided that the product container is embodied axially movably, in such a way that during the downward motion of the stuffing plungers, the product container can be pressed against the stuffing ring. This is accomplished by means of holding-down elements that are movable synchronously with the stuffing plungers.
  • the powder compact can stick to the transfer plunger and thus not drop on its own into the bottom part of a capsule that is standing ready.
  • the transfer plunger is kept in position, just above the segment of the bottom part, until such time as the capsule transporter carrying the circularly arranged bottom-part segments has moved onward by a certain angle. Since the upper edge of the bottom parts of the capsules is located at a lower level than the upper edge of the segment of the bottom part, the powder compacts become sheared off by the transfer plungers at the upper edge of the segments of the bottom part and then either drop into the bottom parts of the capsules or remain sticking to the edge of the bore in the segment of the bottom part.
  • the powder compacts break off unevenly, the result is imprecisions in dosage and dragging or soiling of the product as well as problems in closing the capsules. It is the object of the invention to overcome the aforementioned disadvantages.
  • the device according to the invention for metering a powdered product has the advantage over the prior art that the powder compacts can be knocked clean securely during the transfer operation.
  • a strong force can be exerted on the transfer plungers that are in contact with the product that because of the spontaneous acceleration of the heavy transfer plungers on the one hand and the mass inertia of the very lightweight powder compacts (or product) on the other, a tearing force is exerted that is greater than the forces of adhesion operative until then between the transfer plunger and the powder compact.
  • the powder compacts thus detached then travel in free fall, unhindered, along their further course downward back into the bottom part of the capsule.
  • the drive unit speeds up the transfer plunger counter to the transfer direction.
  • a vehement impetus or impact can shoot the plunger suddenly upward during the fading downward motion, so that especially strong forces act on the plunger.
  • FIG. 1 shows a perspective view of the metering device
  • FIG. 2 is a sectional view through the additional drive unit
  • FIG. 3 shows a further sectional view, rotated by 90° relative to FIG. 2 .
  • the device 10 described thus far serves to meter the product into bottom parts 22 of the capsules that stand ready.
  • the product container 12 is rotated in increments to beneath stuffing plungers 19 , or in the transfer position to beneath the transfer plungers 16 .
  • a product such as powder or pellets, located in the region of the metering openings 14 is forced into the metering openings 14 by a downward motion of the stuffing plunger 19 .
  • the powder compact is thrust by the transfer plunger 16 into the respective bottom part 22 of the capsule by a downward motion of the movement system 24 .
  • the yoke 34 is mechanically coupled via the shafts 32 to the connecting pins 44 to the transfer plunger holder 30 , so that the transfer plungers 16 jerk forcefully counter to the transfer direction.
  • the transfer plunger holder 30 is connected rigidly to the tops of the transfer plungers 16 via the comb 18 . This vehement impetus accelerates the transfer plungers 16 suddenly upward during the fading downward motion.
  • the spontaneous acceleration of the heavy transfer plungers 16 on the one hand and the mass inertia of the very lightweight powder compacts on the other bring about a tearing force that is greater than the forces of adhesion, operative until then, between the transfer plunger 16 and the powder compact.
  • the thus-detached powder blank now traverses the further course downward unhindered, in free fall, into the bottom part 22 of the capsule that is standing ready.
  • the transfer plunger holder 30 moved upward relative to the guide 28 is returned to the original outset position downward in the transfer direction.
  • the transfer plungers 16 can now be moved in the transfer direction relative to the transverse arm 26 by a drive unit 27 .
  • One component of the drive unit 27 is a pneumatic cylinder 36 , with which via a countersunk screw 40 a lifting tappet 38 is connected.
  • the lifting tappet 38 presses against the underside of a yoke 34 that completely covers the lifting tappet 38 .
  • the yoke 34 is in turn, secured via respective screws 33 laterally to shafts 32 oriented in the transfer direction.
  • the shafts 32 are in turn connected on their respective ends to a transfer plunger holder 30 via connecting pins 44 .
  • a comb 18 is disposed in the transfer plunger holder 30 for securing the ends of the transfer plungers 16 to the transfer plunger holder 30 .
  • the transfer plunger holder 30 , comb 18 , shafts 32 , yoke 34 and screws 33 form a unit whose parts are fixed relative to one another and which can move in a guide 28 relative to the transverse arm 26 , in or counter to the transfer direction.
  • the guide 28 is solidly connected to the transverse arm 26 and its plunger guide 17 via a respective screw means 29 .
  • the shaft 32 penetrates the guide 28 via a suitable opening and protrudes past a recess 46 into the interior of the transfer plunger holder 30 so as to be solidly connected to it via the connecting pin 44 .
  • a spring 42 is disposed around each shaft 32 and is braced on its upper side relative to the guide 28 and on its underside relative to the upper side of the transfer plunger holder 30 .
  • the spring 42 serves to return the unit, comprising the transfer plunger holder 30 , shafts 32 , screws 33 , and yoke 34 , to the original outset position, counter to the transfer direction, once a stroke has taken place.
  • the transfer plunger holder 30 is guided substantially in cuplike fashion relative to the guide 28 . This prevents contamination of the transfer plunger holder 30 by the product.
  • the device 10 described thus far serves to meter the product into bottom parts 22 of the capsules that stand ready.
  • the product container 12 is rotated in increments to beneath stuffing plungers, not shown, or in the transfer position to beneath the transfer plungers 16 .
  • a product such as powder or pellets, located in the region of the metering openings 14 is forced into the metering openings 14 by a downward motion of the stuffing plunger, not shown.
  • the powder compact is thrust by the transfer plunger 16 into the respective bottom part 22 of the capsule by a downward motion of the movement system 24 .
  • the yoke 34 is mechanically coupled via the shafts 32 to the connecting pins 44 to the transfer plunger holder 30 , so that the transfer plungers 16 jerk forcefully counter to the transfer direction.
  • the transfer plunger holder 30 is connected rigidly to the tops of the transfer plungers 16 via the comb 18 . This vehement impetus accelerates the transfer plungers 16 suddenly upward during the fading downward motion.
  • the spontaneous acceleration of the heavy transfer plungers 16 on the one hand and the mass inertia of the very lightweight powder compacts on the other bring about a tearing force that is greater than the forces of adhesion, operative until then, between the transfer plunger 16 and the powder compact.
  • the thus-detached powder blank now traverses the further course downward unhindered, in free fall, into the bottom part 22 of the capsule that is standing ready.
  • the transfer plunger holder 30 moved upward relative to the guide 28 is returned to the original outset position downward in the transfer direction.
  • the described device for metering a powdered product is suitable particularly for powder metering devices in the pharmaceutical field.
  • it is not limited to that.
  • Modifications with regard to the drive unit 27 are also possible without departing from the concept of the invention. What is essential is that a sufficiently strong force is exerted on the transfer plunger 16 that any product still adhering is acted upon by such a great force that it drops away from the underside of the transfer plunger 16 .
  • This can be effected hydraulically, pneumatically or electrically, for instance by means of an electric drive mechanism, or by other suitable drive units.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
US12/668,605 2007-07-09 2008-07-01 Device for metering a powdered product Active 2029-12-12 US8453687B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102007031856.3 2007-07-09
DE102007031856 2007-07-09
DE102007031856A DE102007031856A1 (de) 2007-07-09 2007-07-09 Vorrichtung zum Dosieren von pulverförmigem Füllgut
PCT/EP2008/058458 WO2009007275A1 (de) 2007-07-09 2008-07-01 Vorrichtung zum dosieren von pulverförmigem füllgut

Publications (2)

Publication Number Publication Date
US20100200112A1 US20100200112A1 (en) 2010-08-12
US8453687B2 true US8453687B2 (en) 2013-06-04

Family

ID=39720319

Family Applications (1)

Application Number Title Priority Date Filing Date
US12/668,605 Active 2029-12-12 US8453687B2 (en) 2007-07-09 2008-07-01 Device for metering a powdered product

Country Status (6)

Country Link
US (1) US8453687B2 (de)
EP (1) EP2175825B1 (de)
CN (1) CN101686899B (de)
DE (1) DE102007031856A1 (de)
ES (1) ES2553723T3 (de)
WO (1) WO2009007275A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150175279A1 (en) * 2013-12-20 2015-06-25 Fette Engineering GmbH Tamping punch station and method of filling capsules in a tamping punch station
US20160089302A1 (en) * 2014-09-29 2016-03-31 Fette Engineering GmbH Dosing station for a capsule filling machine

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8720497B2 (en) * 2010-02-19 2014-05-13 Oriel Therapeutics, Inc. Direct fill dry powder systems with dosing heads configured for on/off controlled flow
CN103751021A (zh) * 2013-12-30 2014-04-30 浙江华仕力机械有限公司 分体式冲杆定位装置
CN103876937B (zh) * 2014-04-18 2016-04-13 山东新马制药装备有限公司 胶囊充填装置
CN104274329A (zh) * 2014-09-29 2015-01-14 浙江华仕力机械有限公司 冲杆分组调节机构
DE102015206407A1 (de) 2015-04-10 2016-10-13 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
CN105268580B (zh) * 2015-10-23 2018-04-10 浙江绿健胶囊有限公司 一种空心胶囊囊坯自动喷油装置
EP3363421A1 (de) * 2017-02-17 2018-08-22 Harro Höfliger Verpackungsmaschinen GmbH Vorrichtung und verfahren zum befüllen von behältnissen, insbesondere zum befüllen von hartgelatinekapseln
EP3369409B1 (de) 2017-03-02 2023-07-12 Harro Höfliger Verpackungsmaschinen GmbH Vorrichtung und verfahren zum dosieren von pulverförmigem füllgut

Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2050885A1 (en) 1969-10-21 1971-04-29 Fratelh Zanasi SpA, Ozzano Emilia, Bologna (Italien) Syphon dosimeter for pharmaceutical powders
US3893492A (en) * 1973-08-06 1975-07-08 John E Nohren Apparatus and method for accurately dispensing and consolidating powdered material into receptacles
US4062386A (en) * 1975-04-07 1977-12-13 Zanasi Nigris S.P.A. Method and apparatus for the dosing of dense pasty substances
DE2807174A1 (de) 1977-02-21 1978-08-24 Folke Daniel Linden Vorrichtung zum zerreiben oder zerstossen von tabletten, insbesondere von medikamenten
JPS57199533A (en) 1981-06-03 1982-12-07 Mitsubishi Metal Corp Parts loading device of reforming press
US4501307A (en) * 1981-03-18 1985-02-26 Robert Bosch Gmbh Machine for filling and closing two-piece hard gelatine capsules
US5240049A (en) * 1990-12-07 1993-08-31 Macofar S.P.A. Machine for the dosage and introduction of powder products into containers
US5626171A (en) * 1994-04-22 1997-05-06 I.M.A. Industria Macchine Automatiche S.P.A. Apparatus for measuring and dispensing predetermined amounts of powdered material
DE10001068C1 (de) 2000-01-13 2001-05-31 Bosch Gmbh Robert Vorrichtung zum Dosieren und Abgeben von Pulver in Hartgelatinekapseln oder dergleichen
US6327835B1 (en) * 1998-12-03 2001-12-11 I.M.A. Industria Macchine Automatiche S.P.A. Checking and controlling apparatus for use in capsule-packaging machines
DE10211118A1 (de) 2002-03-14 2003-09-25 Bosch Gmbh Robert Vorrichtung zum Dosieren von pulverförmigen Füllgut
DE69905393T2 (de) 1998-12-03 2003-10-23 Ima Spa Dosiervorrichtung für gelatinehartkapseln
WO2004004627A1 (en) 2002-07-03 2004-01-15 I.M.A. Industria Macchine Automatiche S.P.A. A unit for checking the dosing of pharmaceutical material in a capsule filling machine
DE102005039765A1 (de) 2005-08-23 2007-03-01 Robert Bosch Gmbh Sensiervorrichtung
US7210507B2 (en) * 2002-05-13 2007-05-01 B.L. Macchine Automatiche S.P.A. Capsule filling machine
DE102006013160A1 (de) 2005-11-30 2007-05-31 Robert Bosch Gmbh Vorrichtung zum Befüllen eines zu dosierenden Guts
DE102006014496A1 (de) 2006-03-29 2007-10-04 Robert Bosch Gmbh Vorrichtung zum Befüllen von zumindest einer Dosierkammer
DE102006031250A1 (de) 2006-07-06 2008-01-10 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
US7640953B2 (en) * 2005-12-29 2010-01-05 Mg 2 - S.R.L. Machine for filling capsules with a product

Patent Citations (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2050885A1 (en) 1969-10-21 1971-04-29 Fratelh Zanasi SpA, Ozzano Emilia, Bologna (Italien) Syphon dosimeter for pharmaceutical powders
US3893492A (en) * 1973-08-06 1975-07-08 John E Nohren Apparatus and method for accurately dispensing and consolidating powdered material into receptacles
US4062386A (en) * 1975-04-07 1977-12-13 Zanasi Nigris S.P.A. Method and apparatus for the dosing of dense pasty substances
DE2807174A1 (de) 1977-02-21 1978-08-24 Folke Daniel Linden Vorrichtung zum zerreiben oder zerstossen von tabletten, insbesondere von medikamenten
US4501307A (en) * 1981-03-18 1985-02-26 Robert Bosch Gmbh Machine for filling and closing two-piece hard gelatine capsules
JPS57199533A (en) 1981-06-03 1982-12-07 Mitsubishi Metal Corp Parts loading device of reforming press
US5240049A (en) * 1990-12-07 1993-08-31 Macofar S.P.A. Machine for the dosage and introduction of powder products into containers
US5626171A (en) * 1994-04-22 1997-05-06 I.M.A. Industria Macchine Automatiche S.P.A. Apparatus for measuring and dispensing predetermined amounts of powdered material
US6327835B1 (en) * 1998-12-03 2001-12-11 I.M.A. Industria Macchine Automatiche S.P.A. Checking and controlling apparatus for use in capsule-packaging machines
DE69905393T2 (de) 1998-12-03 2003-10-23 Ima Spa Dosiervorrichtung für gelatinehartkapseln
DE10001068C1 (de) 2000-01-13 2001-05-31 Bosch Gmbh Robert Vorrichtung zum Dosieren und Abgeben von Pulver in Hartgelatinekapseln oder dergleichen
US6390330B2 (en) * 2000-01-13 2002-05-21 Robert Bosch Gmbh Apparatus for metering and dispensing powder into hard gelatin capsules or the like
US20010035431A1 (en) 2000-01-13 2001-11-01 Robert Bosch Gmbh Apparatus for metering and dispensing powder into hard gelatin capsules or the like
US6810930B2 (en) * 2002-03-14 2004-11-02 Robert Bosch Gmbh Apparatus for metering powdered filling material
DE10211118A1 (de) 2002-03-14 2003-09-25 Bosch Gmbh Robert Vorrichtung zum Dosieren von pulverförmigen Füllgut
US7210507B2 (en) * 2002-05-13 2007-05-01 B.L. Macchine Automatiche S.P.A. Capsule filling machine
US20040172925A1 (en) 2002-07-03 2004-09-09 Pierantonio Ragazzini Unit for checking the dosing of pharmaceutical material in a capsule filling machine
WO2004004627A1 (en) 2002-07-03 2004-01-15 I.M.A. Industria Macchine Automatiche S.P.A. A unit for checking the dosing of pharmaceutical material in a capsule filling machine
DE102005039765A1 (de) 2005-08-23 2007-03-01 Robert Bosch Gmbh Sensiervorrichtung
DE102006013160A1 (de) 2005-11-30 2007-05-31 Robert Bosch Gmbh Vorrichtung zum Befüllen eines zu dosierenden Guts
US7640953B2 (en) * 2005-12-29 2010-01-05 Mg 2 - S.R.L. Machine for filling capsules with a product
DE102006014496A1 (de) 2006-03-29 2007-10-04 Robert Bosch Gmbh Vorrichtung zum Befüllen von zumindest einer Dosierkammer
DE102006031250A1 (de) 2006-07-06 2008-01-10 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150175279A1 (en) * 2013-12-20 2015-06-25 Fette Engineering GmbH Tamping punch station and method of filling capsules in a tamping punch station
US10569912B2 (en) * 2013-12-20 2020-02-25 Fette Engineering GmbH Tamping punch station and method of filling capsules in a tamping punch station
US20160089302A1 (en) * 2014-09-29 2016-03-31 Fette Engineering GmbH Dosing station for a capsule filling machine
US10449119B2 (en) * 2014-09-29 2019-10-22 Fette Engineering GmbH Dosing station for a capsule filling machine

Also Published As

Publication number Publication date
US20100200112A1 (en) 2010-08-12
CN101686899B (zh) 2013-09-11
DE102007031856A1 (de) 2009-01-15
CN101686899A (zh) 2010-03-31
EP2175825A1 (de) 2010-04-21
ES2553723T3 (es) 2015-12-11
EP2175825B1 (de) 2015-11-04
WO2009007275A1 (de) 2009-01-15

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