US2470297A - Inhalator - Google Patents

Inhalator Download PDF

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Publication number
US2470297A
US2470297A US772104A US77210447A US2470297A US 2470297 A US2470297 A US 2470297A US 772104 A US772104 A US 772104A US 77210447 A US77210447 A US 77210447A US 2470297 A US2470297 A US 2470297A
Authority
US
United States
Prior art keywords
ball
container
chamber
foraminated
inhalation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US772104A
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English (en)
Inventor
Mack R Fields
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE483136D priority Critical patent/BE483136A/xx
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Priority to US772104A priority patent/US2470297A/en
Priority to FR59839D priority patent/FR59839E/fr
Priority to FR967494D priority patent/FR967494A/fr
Priority to NL141155A priority patent/NL68968C/xx
Priority to GB13228/50A priority patent/GB654872A/en
Priority to GB21972/48A priority patent/GB654860A/en
Priority to CH277150D priority patent/CH277150A/fr
Priority to CH278137D priority patent/CH278137A/fr
Priority to DEP30173A priority patent/DE845385C/de
Priority to DEA12922A priority patent/DE846770C/de
Priority to BE489055D priority patent/BE489055A/xx
Application granted granted Critical
Publication of US2470297A publication Critical patent/US2470297A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0018—Details of inhalators; Constructional features thereof with exhalation check valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0098—Activated by exhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/04—Tracheal tubes
    • A61M16/0488—Mouthpieces; Means for guiding, securing or introducing the tubes
    • A61M16/049—Mouthpieces
    • A61M16/0493—Mouthpieces with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0618—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0625—Mouth

Definitions

  • My invention relates to therapeutic medication and includes among its objects and advantages increased convenience in medication with dry medicaments in powder form, especially with respect to accuracy of dosage and accurate placement of the material.
  • vasoconstrictors In addition to Water-soluble anti-biotics, solid inhalation therapy is of value in connection with certain vasoconstrictors, and is indicated for at least some of the known anti-histamine drugs.
  • vaso-constrictors are: epinephrine hydrochloride, isopropyl epinephrln and 2-aminoheptane.
  • anti-histamine agents are: N-(alpha-pyridyD- N (alpha-thenyl) N', N dimethylethylenediamine hydrochloride, and N-(alpha-pyridyl) -N- (benzyl) -N',N-dimethylethylenediamine hydrochloride.
  • I succeed in obtaining such constancy by providing apparatus which is to be utilized by the patient by breathing in and out in a simple, substantially normal way.
  • I utilize the energy of the -patients breathing to deliver into each charge of air inhaled a small substantially constant charge of powdered medicament, which charge is delivered quickly, shortly after inhalation begins, and nds its way to the depth of the cavity long before inhalation is finished.
  • the apparatus itself and the nose and bronchial tubesl are thoroughly swept and scavenged with pure air during a major portion of the breathing-in-process.
  • administration in this way not only contributes to deep penetration of the medicament, but that it becomes unnecessary to pulverize or micronizev the medicament into a true smoke.
  • the use of larger particles tends to increase the reliability with which a uniform fraction of the material will passl on through the nose and bronchial tubes without getting caught on the moist Walls.
  • Figure l is a side elevation of an inhalator according to the invention:
  • Figure 2 is a plan view of the same inhalator :from above;
  • Figure 3 is a plan view of the same inhalator from below;
  • Figure 4 is a section as on line 4-4 of Figure 2;
  • Figure 5 is a longitudinal section of the capsule before it is assembled with the inhalator.
  • Figure 6 is a perspective ⁇ of the device in use.
  • the main housing IIJ is of transparent plastic,A molded in two halves cemented together on the plane of the section of Figure 4.
  • the body deilnes achamberJZ having an outlet opening I4 for the discharge of air into the mouth of the patient.
  • Flanges I6 assist the patient in holding the device in place with the teeth as partially indicated in dotted lines in Figure 1.
  • the top opening I8 closed by a. plug 20 when it happens that medication through the mouth only is desired. Normally, it will receive a lower end of a bifurcated nose connector piece 22. This is of flexible material with its lower end ,fitted into the opening I8 and the two tips 24 entered inthe nostrils of the patient.
  • the bottom portion may advantageously have a wall thickness of about 68 thousandths of an inch, which will secure a satisfactory grip in the opening, and the wall may taper to about 30 thousandths of an inch at the end of the tip so that the tips 24 will be soft and comfortable to the users nostrils.
  • Means are provided for discharging a predetermined amount of powdered medicament small enough in quantity to be carried into the air-filled cavity receiving it during a first and preferably minor fraction of each breathing in, or inhalation.
  • the chamber I2 has another inlet 40 in its bottom controlled by the simple flap check valve 42. It will be apparent that at the beginning of each inhalation the ap 42 closes immediately and the suction exerted by the patient then throws the ball 34 quickly from the bottom of the tube 32 up into ycontact with the capsule 28.
  • simple steel ball functions very well in this connection, but with a ball of aluminum the parts may be designed to secure a slightly better mechanical action,
  • the inner end of the tube 32 is provided with four slots 44 extending down the tube far enough so that the ball uncovers and opens them when it moves to the upper end of its path. Thus, ⁇ the user does not experience any material restriction on his breathing.
  • a rubber cap 46 which, in undistorted condition, has its bottom dished upward as indicated at 48 in Figure so that pushing thecap home on the lower end of the capsule will stress the bottom 48 and cause it to remain gently pressed upward against the screen 30 until the cap is removed preparatory to using the capsule.
  • the upper portion of the capsule is shaped for convenient handling by the user.
  • a plastic capsule which may be formed initially with a middle diaphragm 50 at the top of the capsule proper 26, and substantially arcuate closed wall sections rising above the diaphragm 50 and of slightly larger diameter than that of the capsule proper 26 to dene an abutment shoulder 52 to engage the grommet 26.
  • various powdered medicaments can be administered at various rates.
  • sodium penicillin I prefer to use a screen of about 60 mesh and it is not hard to granulate the powder by trial and error to a grain size such that an administration of 100,000 units is easily accomplishedby normal breathing, in from three to six minutes.
  • smoother and more accurate mechanical action can be secured by mixing the penicillin with at least a little other material intended to function as a diluent or vehicle.
  • 100,000 units of graular penicillin represents about 90 milligrams of material and the addition to the charge of about 25 milligrams of sulfanilamide makes up into a combined powder that secures materially better and more accurate mechanical functioning.
  • a patient inhaling such a charge will receive a full normal dose of penicillin but only about 10% of a normal dose of sulfanilamide.
  • the charge may include various combinations of medicaments with or without completely inert vehicles.
  • Equipment for introducing an air-borne powdered medicament into body cavities which comprises: a rigid transparent plastic body dening a chamber; said chamber being formed with one end outlet shaped to be gripped between the teeth of the user; said chamber having a lateral outlet positioned below the users nostrils when said first outlet is gripped by the users teeth; a flexible branched conduit having a single lower opening fitting said second chamber outlet, and double upper openings of va size to t into the nostrils of the user; said upper openings being deflnedby flexible material; a tubular inlet at the end of the chamber opposite said first outlet; a ball of diameter sufficient to substantially close said tubular inlet; said tubular inlet being inclined so that the ball normally resides at the intake end of said inlet; an obstruction at the intake end of said inlet end to prevent egress of said ball; an obstruction at the discharge end of said tubular inlet to prevent discharge of said ball into said chamber; said tubular inlet having lateral vent opening adjacent its discharge end positioned to be uncovered by said ball
  • -socket means in the wall oi said chamber for receiving and holding said container in a position to. be struck by said ball at-the end of its inward movement; said container having a foraminated bottom; and a charge of powdered medicament in said container of grain size small enough to deliver an increment of medicament through said foraminated bottom each time said ball strikes said container at the beginning of inhalation; a return flow discharge opening in said chamber, and a quick-acting check valve permitting gas to issue from said chamber during exhalation but closing at the beginning of inhalation to compel the air inhaled to enter through said tubular inlet.
  • Equipment for introducing an air-borne medicament into body cavities which'comprises: a rigid transparent plastic body dening a chamlber; said chamber being formed with one end outlet shaped to deliver uid to the mouth of the user: said chamber having a lateral outlet positioned below the users nostrils when said rst outlet is gripped by the users teeth; a conduit means for delivering gas from said second chamber outlet into the nostrils of the user; a tubular inlet at the end of the chamber opposite said first outlet: a ball of diameter sufilcient to substantially close said tubular inlet; said tubular inlet being inclined so that the ball normally resides at the intake end of said inlet; an obstruction at the intake end of said inlet end to prevent egress of said ball; an obstruction at the discharge end of said tubular inlet to prevent discharge of said ball into said chamber; said tubular inlet having lateral vent openings adjacent its discharge end positioned to be uncovered by said ball; a removable container for medicament; socket means in the wall of said chamber for receiving said container
  • said container having a foraminated bottom; and a charge of powdered -medicament in said container of grain size small enough to deliver an increment of medicament through said ioraminated bottom each time said ball strikes said container at the beginning of inhalation; a. return flow discharge opening in said chamber: and a quick-acting check valve permitting gas to issue from said chamber during exhalation but closing at the beginning of inhalation to compel .the air inhaled to enter through said tubular inlet.
  • Equipment for introducing' an airborne powdered medicament into body cavities which comprises: a body dening 'a chamber; said chamber being formed with an outlet shaped to deliver iluid -to the person o! the user; an inlet to said chamber; a medicament container in said chamber having a foraminated Wall; means actuated by the initial flow of inhaled gas through said inlet, for jolting said container to release an increment of medicament through said i'oraminated wall; said chamber being provided with an additional outlet for the exit of gas during exhalation; and an automatic check valve in said additional outlet to prevent inward flow.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
US772104A 1947-09-04 1947-09-04 Inhalator Expired - Lifetime US2470297A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
BE483136D BE483136A (is") 1947-09-04 1942-06-15
US772104A US2470297A (en) 1947-09-04 1947-09-04 Inhalator
FR59839D FR59839E (fr) 1947-09-04 1948-06-10 Dispositif inhalateur
FR967494D FR967494A (fr) 1947-09-04 1948-06-10 Dispositif inhalateur
NL141155A NL68968C (is") 1947-09-04 1948-06-24
GB21972/48A GB654860A (en) 1947-09-04 1948-08-20 Improvements in or relating to therapeutic medication
GB13228/50A GB654872A (en) 1947-09-04 1948-08-20 Improvements in or relating to therapeutic medication
CH277150D CH277150A (fr) 1947-09-04 1948-09-04 Récipient pour produit pulvérisé.
CH278137D CH278137A (fr) 1947-09-04 1948-09-04 Inhalateur.
DEP30173A DE845385C (de) 1947-09-04 1949-01-01 Vorrichtung zum Verabreichen von Medikamenten durch Inhalation
DEA12922A DE846770C (de) 1947-09-04 1949-01-01 Medikamentenbehaelter
BE489055D BE489055A (is") 1947-09-04 1949-05-16

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US772104A US2470297A (en) 1947-09-04 1947-09-04 Inhalator

Publications (1)

Publication Number Publication Date
US2470297A true US2470297A (en) 1949-05-17

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
US772104A Expired - Lifetime US2470297A (en) 1947-09-04 1947-09-04 Inhalator

Country Status (7)

Country Link
US (1) US2470297A (is")
BE (2) BE483136A (is")
CH (2) CH277150A (is")
DE (2) DE845385C (is")
FR (2) FR967494A (is")
GB (2) GB654860A (is")
NL (1) NL68968C (is")

Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2503732A (en) * 1949-01-28 1950-04-11 Wyeth Corp Inhalator
US2590832A (en) * 1949-03-29 1952-03-25 Frederick M Turnbull Inhaler with closure
US2641254A (en) * 1948-10-18 1953-06-09 Frederick M Turnbull Applicator
US2722935A (en) * 1949-03-22 1955-11-08 Robert E Thompson Powder dispenser
US2809634A (en) * 1956-08-07 1957-10-15 Murai Hirotada Inhaling and sniffing pipe
US3508543A (en) * 1967-04-27 1970-04-28 Orlando T Aulicono Mouth-to-mouth and nose resuscitation device
USD262322S (en) 1979-07-23 1981-12-15 Mizerak Vladimir S Nasal cannula mouth mask
US4722326A (en) * 1985-11-04 1988-02-02 Ruderian Max J Vibratory therapeutic device
US4846168A (en) * 1986-12-05 1989-07-11 Mect Corporation Inhaler
US4886493A (en) * 1987-10-22 1989-12-12 Jordan Yee Medical applicator process
EP0626180A1 (de) 1993-05-28 1994-11-30 PAUL RITZAU PARI-WERK GmbH Mundstück für Inhalationstherapiegeräte
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
US5676643A (en) * 1995-02-13 1997-10-14 The Procter & Gamble Company Dispenser for friably releasing dry particulate medicaments
US5683361A (en) * 1991-12-10 1997-11-04 Novo Nordisk A/S Disposable dispenser for powder
US5797392A (en) * 1996-01-22 1998-08-25 Direct-Haler A/S Inhaler
WO1998041256A3 (en) * 1997-03-14 1999-02-11 Astra Ab Inhalation device
US5989217A (en) * 1996-03-21 1999-11-23 Unisia Jecs Corporation Medicine administering device for nasal cavities
US6055979A (en) * 1996-04-02 2000-05-02 Ing. Erich Pfeiffer Gmbh Dosing and discharging device for flowable media including powder/air dispersions
US6065471A (en) * 1994-09-16 2000-05-23 Laboratoire Glaxo Wellcome Inhalation device
WO2000051672A1 (en) * 1999-03-03 2000-09-08 Optinose As Nasal delivery device
US6230707B1 (en) * 1993-07-30 2001-05-15 Hoerlin Ernst Powder inhaler
US20010027790A1 (en) * 2000-02-01 2001-10-11 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6513519B2 (en) 1999-12-22 2003-02-04 Pari Gmbh Spezialsten Fur Effective Inhalation Inhalation atomizer with a one-piece valve element
WO2002068030A3 (en) * 2001-02-26 2003-02-06 Optinose As Nasal devices
US6606990B2 (en) 1998-01-16 2003-08-19 Pari Gmbh Spezialisten Fur Effektive Inhalation Mouth piece for inhalation therapy units
WO2003084591A1 (en) * 2002-04-04 2003-10-16 Optinose As Nasal devices
WO2003090812A3 (en) * 2002-04-25 2003-12-31 Optinose As Nasal devices
WO2004004814A3 (en) * 2002-07-02 2004-05-21 Optinose As Nasal devices
RU2258538C2 (ru) * 1999-03-03 2005-08-20 Оптиноуз Ас Носовое подающее устройство
US20060054165A1 (en) * 2002-12-19 2006-03-16 Scadds Incorporated Self contained aerosol dual delivery system (SCADDS)
US20060081246A1 (en) * 2002-01-24 2006-04-20 Joachim Goede Pharmaceutical powder cartridge, and inhaler equipped with same
US20100012120A1 (en) * 2006-12-22 2010-01-21 Laboratorios Almirall, S.A. Inhalation device for drugs in powder form
US20120006323A1 (en) * 2001-06-12 2012-01-12 Optinose As Nasal devices
WO2011151479A3 (es) * 2010-05-19 2012-03-08 Javier Ernesto Maselli Respirador - dispositivo de reanimacion rcpb
US20130032145A1 (en) * 2008-05-01 2013-02-07 Dan Adler Dry powder inhaler
US20140096770A1 (en) * 2012-10-05 2014-04-10 Lily A. Neff Salt puffer
WO2014004400A3 (en) * 2012-06-28 2014-04-17 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nasal dry powder delivery system for vaccines and other treatment agents
US20150013677A1 (en) * 2012-02-24 2015-01-15 Optinose As Nasal Delivery Devices
EP2965775A1 (en) * 2008-01-24 2016-01-13 Vectura Delivery Devices Limited Inhaler
US20160228663A1 (en) * 2014-10-27 2016-08-11 Human Design Medical, Llc Nasal mask for use in various positive airway pressure supply systems
USD776252S1 (en) * 2012-07-17 2017-01-10 Rhinosystems, Inc. Nasal irrigation device
US9883932B2 (en) 2009-10-19 2018-02-06 Aircom Manufacturing, Inc. Transdermal dispensing apparatus and methods
US10478574B2 (en) * 2006-01-19 2019-11-19 Optinose As Nasal administration
US20200268999A1 (en) * 2019-02-27 2020-08-27 Mackay Memorial Hospital Respiratory mask
US10765829B2 (en) 2006-07-25 2020-09-08 Optinose As Delivery of gases to the nasal airway
US11065410B1 (en) * 2021-02-01 2021-07-20 Leonard Feld Dental appliance using airway dialation for treating covid related breathing disorders
US11083858B2 (en) * 2007-10-03 2021-08-10 Optinose As Nasal delivery devices
US11291751B2 (en) 2006-11-06 2022-04-05 Aardvark Medical, Inc. Irrigation and aspiration device and methods
USD950711S1 (en) * 2021-06-11 2022-05-03 ChongQing Moffy Innovation Technology Co., Ltd. Nasal irrigator
USD1048571S1 (en) 2021-10-07 2024-10-22 Masimo Corporation Bite block

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
DE1047385B (de) * 1952-03-08 1958-12-24 Armour & Co Puderzerstaeuber mit einem auswechselbaren Puderbehaelter
FI69963C (fi) * 1984-10-04 1986-09-12 Orion Yhtymae Oy Doseringsanordning
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
CA2069753A1 (en) * 1990-07-27 1992-01-28 Franco Del Bon Inhalation device
CA2093809A1 (en) * 1991-08-15 1993-02-16 Franco Del Bon Inhaler
AT398277B (de) * 1992-12-11 1994-11-25 Hurka Wilhelm Inhalationsgerät
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
GB2299034A (en) * 1994-09-14 1996-09-25 Nippon Denso Co Deodorizing filter
EP0837710B1 (en) * 1995-06-21 2001-11-28 ASTA Medica Aktiengesellschaft Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
DE19522415C2 (de) * 1995-06-21 2003-12-04 Sofotec Gmbh & Co Kg Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone
DE10202940A1 (de) 2002-01-24 2003-07-31 Sofotec Gmbh & Co Kg Patrone für einen Pulverinhalator
JP4621736B2 (ja) 2004-07-16 2011-01-26 アルミラル ソシエダツド アノニマ 粉末薬剤を投与するための吸入器、及びこの吸入器と共に使用するための粉末カートリッジシステム

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE471490C (de) * 1931-08-12 Karl Zeyen Vorrichtung zum Zerstaeuben mehlfoermiger Stoffe
US2214032A (en) * 1939-06-23 1940-09-10 Walter B Stewart Apparatus for administering powdered aluminum

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE471490C (de) * 1931-08-12 Karl Zeyen Vorrichtung zum Zerstaeuben mehlfoermiger Stoffe
US2214032A (en) * 1939-06-23 1940-09-10 Walter B Stewart Apparatus for administering powdered aluminum

Cited By (115)

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Also Published As

Publication number Publication date
CH278137A (fr) 1951-09-30
CH277150A (fr) 1951-08-15
NL68968C (is") 1951-06-15
FR967494A (fr) 1950-11-03
GB654872A (en) 1951-07-04
BE483136A (is") 1942-06-30
DE846770C (de) 1952-08-18
DE845385C (de) 1952-11-04
GB654860A (en) 1951-07-04
BE489055A (is") 1949-06-15
FR59839E (fr) 1954-08-23

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