US20100211029A1 - Aspiration system for removing liquid other than urine discharged by the human body - Google Patents
Aspiration system for removing liquid other than urine discharged by the human body Download PDFInfo
- Publication number
- US20100211029A1 US20100211029A1 US12/738,332 US73833208A US2010211029A1 US 20100211029 A1 US20100211029 A1 US 20100211029A1 US 73833208 A US73833208 A US 73833208A US 2010211029 A1 US2010211029 A1 US 2010211029A1
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- United States
- Prior art keywords
- liquid
- sensor
- interface device
- aspiration system
- body interface
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Images
Classifications
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- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
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- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
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- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
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- A61F5/451—Genital or anal receptacles
- A61F5/455—Genital or anal receptacles for collecting urine or discharge from female member
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/71—Suction drainage systems
- A61M1/73—Suction drainage systems comprising sensors or indicators for physical values
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- A—HUMAN NECESSITIES
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- A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3379—Masses, volumes, levels of fluids in reservoirs, flow rates
- A61M2205/3386—Low level detectors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
Definitions
- the present invention relates to an aspiration system for use in removing liquids discharged by the human body.
- the invention may be used for removing body fluids and secretions other than urine.
- One aspect of the invention relates to removal of wound exudate.
- Wound exudate can be described as the liquid produced from chronic wounds, fistula, or acute wounds once haemostasis has been achieved. For centuries, the production of exudate was regarded as inevitable with certain types of wound, and inconsequential with respect to wound healing.
- Negative pressure means pressure below surrounding atmospheric pressure.
- TNP Topical Negative Pressure
- an aspiration system and method for removing liquid other than urine, which liquid is discharged from the human body.
- the system comprises a disposable body interface device having a liquid collection chamber.
- a liquid sensor detects the presence of liquid within the chamber.
- the application of aspiration suction to remove liquid from the liquid collection region is controlled responsive to the output of body fluids and secretions detected by the liquid sensor.
- the body interface device may be a wound dressing to allow controlled draining of the liquid wound exudate.
- the aspiration suction can be controlled to remove only excess wound exudate, according to the output of body fluids and secretions detected by the liquid sensor.
- FIG. 1 is a schematic block diagram of a first embodiment of aspiration system for collecting and removing liquid wound exudate discharged by a wound of the human body, the diagram including an exploded sectional view of the wound dressing components.
- FIG. 2 is a schematic sectional view showing, in exploded form, a modification of the wound dressing from FIG. 1 .
- FIG. 3 is a schematic diagram showing operation of the aspiration system in graphical form.
- an aspiration system 10 for removing body liquid (other than urine) discharged or secreted by the human body generally comprises: a body interface device 14 ; and an aspiration unit 12 for applying suction to the body interface device 14 to aspirate the body liquid.
- the present embodiment illustrates an aspiration system 10 specifically for removal of wound exudate from a wound site 18 .
- the body interface device 14 is in the form of (and is hereafter referred to as) a wound dressing, configured for fitting to the body at, or around, the wound site 18 .
- the field of wound dressings with exudate aspiration is quite unique, and very different from the field of, for example, urine removal.
- Urine is usually discharged as a gush of liquid, and a urine removal system should remove all urine to leave the skin dry in order to avoid irritation and infection.
- wound exudate is not discharged in a gush, and it is not desirable to remove all of the wound exudate.
- the exudate contains a complex mixture of bioactive molecules that have both positive and negative effects. While removal of excess exudate is desirable, removal of all exudate may hinder rather than aid wound healing. Instead, the present embodiment aims to manage the amount of wound exudate, and remove excess from the wound site.
- a liquid sensor 30 for detecting liquid exudate in the wound dressing 14 .
- the liquid sensor 30 generates a signal 32 indicative of sensed liquid.
- the sensor 30 may detect one or both of the following parameters: (i) proximity of liquid, and/or (ii) a quantity of liquid within sensing range.
- the aspiration unit 12 is responsive to the sensor signal 32 in order to control the application of aspiration suction.
- the wound dressing 14 is preferably attachable to the patient's skin 20 by means of an adhesive pad 26 .
- the adhesive pad 26 has a closed loop shape that circumscribes the periphery of the wound site 18 .
- the adhesive pad 26 extends over the wound site 18 , and has perforations or apertures 27 to permit passage of exudate from the wound site 18 into the wound dressing 14 .
- the adhesive pad 26 is made of a skin-friendly medical grade adhesive. Examples of suitable adhesives include pressure-sensitive adhesives that may be any of hydrocolloid, polyurethane, acrylic, thermoplastic elastomer (TPE), hydrogel, or silicone-based.
- the wound dressing 14 may have any suitable construction for covering the wound site 18 , defining a liquid collection region and at least partly a local environment conducive to wound healing.
- the wound dressing 14 may be the same as, or similar to, the dressings shown in any of the aforementioned U.S. Pat. Nos. 4,969,880, 5,636,643, 5,645,081, 7,216,651, and/or U.S. Publication Nos. 2001/0029956 and 2006/0100594.
- the wound dressing 14 typically comprises a cover 16 extending over the wound site 18 , and overlapping healthy peri-wound tissue.
- the wound dressing 14 may optionally contain or comprise a liquid handling material 24 ( 24 a, 24 b ).
- the liquid handling material 24 may, for example, be a material for absorbing exudate without gelling. Such a material may be non-woven and/or a foam. Such a non-woven material could be hydrophobic or hydrophilic, synthetic or natural.
- the liquid handling material 24 may alternatively be, or comprise, a fibrous blend or fibrous material (e.g., a non-woven) that forms a cohesive gel when wetted with wound exudate.
- a fibrous material can be provided, for example, by the wound contact layer of the Versiva® dressing (ConvaTec Inc., Skillman, N.J.) or by a fibrous mat of sodium carboxymethylcellulose.
- a fibrous mat of sodium carboxymethylcellulose is available as AQUACEL® dressing from ConvaTec Inc., as is a similar dressing further including silver.
- Other exemplary materials for the liquid handling material 24 include MedicelTM, CarboxflexTM (which provides an odor absorbent layer with fibrous material for wicking liquid away from the odor absorbent), HyalofillTM (forming a hyaluronic acid-rich fibrous gel) or KaltostatTM (containing alginate) dressings from ConvaTec Inc. While the liquid handling layer 24 has the ability to absorb the exudate quickly, it also allows exudate to be pumped away under suction.
- a combination of both a non-gelling liquid handling layer 24 a and a fibrous gelling layer 24 b may be used, for example, in distinct layers.
- the layers 24 a and 24 b may be bonded to each other, or they may be contained as separate layer components within the wound dressing 14 .
- FIG. 1 illustrates an optional perforated screen 28 that may be used, for example, to enclose such layers 24 a and 24 b.
- liquid handling layer 24 b maybe perforated to allow excess exudate to be absorbed by liquid handling layer 24 a.
- An aspiration source connector 22 extends into the wound dressing 14 for delivering aspiration suction from the aspiration unit 12 .
- the connector 22 extends through the cover 16 , although the connector 22 could enter the wound dressing 14 at any suitable point.
- the point at which suction is applied is separated from the wound site 18 by at least a portion of the liquid handling material 24 .
- the point at which suction is applied is spaced from the wound site 18 by at least the gelling layer 24 b, and preferably also by at least a portion of the non-gelling layer 24 a.
- a flexible conduit 35 couples the wound dressing 14 to the aspiration unit 12 .
- a releasable connector or an easy release coupling may be provided at one end, or both ends, of the conduit 35 .
- the flexible conduit 35 may be regarded as part of the aspiration unit 12 and/or part of the body interface device 14 .
- the flexible conduit 35 links the connector 22 to a suction source 40 within the aspiration unit 12 .
- the aspiration unit 12 comprises a power supply 38 , an electronic control unit 44 , and the suction source 40 .
- the power supply 38 is selected as one or more of: a replaceable battery, a rechargeable battery, radiation collection panels, and a mains power supply.
- the power supply 38 includes a combination of a rechargeable battery and a mains power supply; such a combination allows portable operation when the aspiration system 10 is not connected to a mains power supply, as well as automatic recharging of the battery when the aspiration system 10 is coupled to a mains power supply.
- the power supply 38 includes radiation collection panels, such as photovoltaic panels or cells for generating electricity from ambient light, which can improve autonomy of operation or for charging the rechargeable battery.
- the power supply 38 may provide power for any one or more of: the electronic control unit 44 , the liquid sensor 30 (if needed) and any power needed by the suction source 40 .
- the suction source 40 is an electric pump that operates under control of the electronic control unit 44 .
- the pump 40 could be a suction device based on diaphragm, peristaltic, volume displacement, spring, gravity, siphon, heat-recoverable metal drive, or an in-line pump.
- the flexible conduit 35 is coupled through the pump 40 to a liquid collection chamber 42 for collecting exudate removed from the wound dressing 40 .
- the liquid collection chamber 42 may either be separate from the aspiration unit 12 (as illustrated) and coupled thereto with a suitable connector, or the liquid collection chamber 42 may be integral with and/or housed in the aspiration unit 12 (arrangement not shown).
- the suction source 40 may comprise a vacuum chamber charged with a low pressure vacuum, and an electronically controlled valve for controlling application of suction from the vacuum chamber to the flexible conduit 35 .
- a pump may be provided for charging the vacuum chamber with the vacuum.
- the liquid sensor 30 may be separate or separable from the wound dressing 14 , enabling replacement of the wound dressing 14 without having to use a new sensor 30 .
- a means is preferably provided for releasably attaching the sensor 30 to the wound dressing 14 .
- the liquid sensor 30 may be permanently attached to the wound dressing 14 to form an integral unit. With permanent attachment, the liquid sensor 30 is intended to be disposed of with the wound dressing 14 .
- the sensor signal 32 is typically an electrical or electronic signal. However, other signal forms may be used as desired, for example, optical.
- the sensor 30 may generate output signal 32 that varies in accordance with the sensed parameter(s).
- the output signal 32 may be a varying analog signal (e.g., variable current or voltage), or the output signal 32 may be a digital signal (e.g., a quantized representation, or a variable pulsed representation).
- the output signal 32 may be a logical (e.g., binary, or on/off) signal indicating whether or not the sensed parameter exceeds or is below one or more thresholds.
- the liquid sensor 30 is preferably a non-contact sensor that is able to detect the presence or proximity of liquid without contact with the liquid.
- the liquid sensor 30 generates an electrical output signal responsive to proximity of detected liquid.
- the electrical signal is communicated to the aspiration unit 12 either via the conduit 35 , or via a separate wire or wireless connector.
- a wired electrical connector may also supply power from the aspiration unit 12 to power the liquid sensor 30 .
- the feature of the liquid sensor 30 being a non-contact sensor provides significant advantages because: (i) the non-contact approach automatically avoids any concerns about passing an electrical current through liquid in contact with the skin 20 and wound site 18 . Instead, there is no direct contact between the liquid sensor 30 and the liquid; (ii) the non-contact approach means that the liquid sensor 30 is not contaminated by touching the liquid exudate. This allows the liquid sensor 30 easily to be reused with a different wound dressing 14 ; and (iii) the non-contact approach means that the liquid sensor 30 does not itself have to be in a sterile condition before use, thus avoiding the difficulty of, or risk of damage when, sterilizing the aspiration system 10 that does interface intimately with the body.
- the feature of the liquid sensor 30 being coupled to the aspiration unit 12 by an electrical connector avoids the expense and fragility associated with using an optical fiber connection.
- the liquid sensor 30 is separate from, or at least separable from, the wound dressing 14 .
- the wound dressing 14 may be a disposable item that may be manufactured inexpensively, and disposed of after a single use, or a limited number of uses.
- the liquid sensor 30 may be more expensive, but may be intended to be used plural times, preferably, with a sequence of different wound dressings 14 used during wound treatment. This enables the aspiration system 10 to be produced and used very cost efficiently, since the disposable components are generally low cost. The higher cost components may be used multiple times, and may require infrequent replacement.
- the liquid sensor 30 is a universal device that may be used with any of a plurality of different types of wound dressings 14
- the non-contact sensor may be permanently attached to the wound dressing 14 , and not be a re-usable item.
- the liquid sensor 30 can take a variety of different forms.
- the liquid sensor 30 is selected from: a capacitance sensor; an ultrasonic sensor; and a piezo-electric (or piezo-resonant) sensor.
- a capacitance sensor detects proximity of liquid according to changes in the dielectric effect of liquid proximity, compared to air proximity. The dielectric effect affects the electric field in the active zone around the sensor, and thus, the effective capacitance in the sensor.
- the capacitance is monitored by any suitable capacitance sensing circuit (not shown), such as an RC oscillator whose oscillation frequency and/or whether oscillation occurs, is dependent on the value of a resistor in combination with the effective capacitance of the sensor.
- the oscillation in turn triggers an output stage, coupled to an output amplifier, to generate an output signal indicative of liquid presence.
- the capacitance sensing circuit is preferably disposed near or at the liquid sensor 18 (e.g., as part of the liquid sensor 18 itself), or the capacitance sensing circuit can be disposed at the aspiration unit 12 , or at a point along electrical connector 35 .
- a suitable capacitance sensor and capacitance sensing circuit are described in U.S. Pat. No. 5,576,619, the contents of which are hereby incorporated by reference.
- the ability to detect liquid has been tested using a capacitance “smart” sensor from SIE Sensors.
- the sensor 30 of dimension 35 mm (length) ⁇ 22 mm (width) ⁇ 10 mm (height) was affixed to the external wall of a body interface device 14 .
- the sensor 30 detected the presence of two test liquids, water and saline solution, as soon as the liquid was introduced, and provided an activation signal to the aspiration unit 12 within milliseconds.
- the electric field from the sensor 30 is able to penetrate a wide variety of plastic components (e.g., polyethylene (PE), polypropylene (PP) and acrylics), either transparent or opaque, with great sensitivity.
- An ultrasonic sensor works using the principle of sonar at the ultrasonic frequency range.
- a transducer is resonated at a set frequency to convert electric energy into ultrasonic frequency range acoustic energy.
- the ultrasonic acoustic waves are emitted towards a liquid collection region.
- Energy is reflected either from the walls if the region is empty of liquid, or from liquid if present in the region.
- An example of ultrasonic liquid sensor is described in U.S. Pat. No. 3,960,007, the content of which is incorporated herein by reference.
- a commercially available ultrasonic sensor is made available by ZEVEX Inc.
- a piezo-electric or piezo-resonant sensor also uses high frequency, e.g., ultrasonic energy or acoustic signal, in a similar way to the ultrasonic sensor described above.
- the ultrasonic or acoustic signal could penetrate either transparent or opaque plastic walls.
- An example of piezo-electric sensor is described in U.S. Pat. No. 3,948,098, the content of which is incorporated herein by reference.
- the ability to detect liquid has been tested with a piezo-resonant sensor obtained from GEMS Sensors.
- the sensor 30 of diameter 40 mm was attached to the external wall of the body interface device 14 , and detected the presence of liquid as soon as introduced.
- the liquid sensor 30 is disposed outside the wound dressing 14 , or at least outside a liquid collection region of the wound dressing 14 .
- the cover 16 is typically made of material through which the sensing electric field can pass in the case of a capacitance sensor, or through which an ultrasonic vibration can pass in the case of an ultrasonic and/or piezo-electric sensor.
- the cover 16 may be made suitably thin to provide the sensor 30 with the desired sensitivity to liquid within the body interface device 14 .
- the cover 16 may include a window portion made of material through which the electric field or ultrasonic vibration can pass easily if the entire cover 16 is not made of such a material.
- the housing of the wound dressing 14 can be shaped into a pocket with or without membrane, for receiving and retaining a capacitive, ultrasonic or piezo-electric non-contact liquid sensor 30 .
- a capacitive, ultrasonic or piezo-electric non-contact liquid sensor 30 can be shaped into a pocket with or without membrane, for receiving and retaining a capacitive, ultrasonic or piezo-electric non-contact liquid sensor 30 .
- Such a design also increases the interface area between the sensor 30 and the liquid collection region of the wound dressing 14 .
- the senor 30 is an electro-optical sensor.
- the cover 16 comprises a window region (not shown) made of material that is transparent to the optical radiation used by the electro-optical sensor.
- the optical radiation may be in the infra-red range, and/or the visible range, and/or ultra-violet range.
- the term “optical” as used herein means that the radiation lies in a frequency range that obeys substantially the laws of optics.
- the electro-optical sensor comprises an electro-optical emitter, an electro-optical receiver, and sensing circuitry for detecting the presence of liquid according to the electrical output of the electro-optical receiver.
- the sensing circuitry is preferably disposed at the liquid sensor 30 (e.g., as part of the liquid sensor 30 ), or the sensing circuitry is disposed at the aspiration unit 12 , or at a point along electrical connector 35 .
- An example electro-optical liquid sensor is described in U.S. Pat. No. 4,354,180, the content of which is incorporated herein by reference.
- the liquid sensor may be disposed at a position 30 a in contact with exudate inside the wound dressing 14 , even if the sensor 30 does not rely on direct contact to detect the liquid.
- a contact-based sensor 30 instead of a non-contact sensor 30 .
- An example of a contact-based sensor 30 is an electrical resistance sensor that detects liquid by conductance between electrodes in contact with the liquid.
- the liquid sensor 30 may be held in an operative position with respect to the wound dressing 14 by a detachable attachment device (not shown) for releasably attaching the liquid sensor 30 to the wound dressing 14 .
- the detachable attachment device could comprise a peelable adhesive, or a peelable mechanical fastener, such as Velcro, or a mechanical coupling based on interference fitting, or other mechanical means.
- a goal of this embodiment is to manage wound exudate, so that excess exudate is removed efficiently while leaving a residual amount of exudate in the wound dressing 14 .
- the amount of wound exudate in the dressing 14 will rise progressively from zero as exudate is accumulated (for example, in the material(s) 24 ).
- the sensor 30 and the control unit 44 co-operate to control the suction source 40 to keep the amount of exudate at a desired level. While the level could be indicated by a single threshold, preferably two thresholds THR-on and THR-off are used to introduce hysteresis to avoid the pump 40 being switched frequently.
- the upper threshold THR-on defines a threshold at which the pump 40 is switched to an aspiration mode (e.g., turned-on), and the lower threshold THR-off defines a threshold at which the aspiration is reduced or deactivated (e.g., pump 40 turned off), to stop further substantial remove of exudate.
- the amount of wound exudate will therefore fluctuate between the two thresholds, with the pump 40 being switched at successive time points T 1 , T 2 and T 3 , for example.
- the thresholds THR-on and THR-off may optionally be adjusted manually by means of a manual control 46 of the aspiration unit 12 . This may allow medical practitioners to control variably the “wetness” of the wound site 18 , and allow different healing environments to be established as desired by a medical practitioner.
- the control 46 may enable both thresholds to be adjusted. Alternatively, one of the thresholds may be fixed at a predetermined level. Alternatively, the difference between the thresholds may be variable, or may be fixed at a predetermined level.
- the control unit 44 may function to apply the thresholds to the sensor signal 32 .
- the sensor 30 itself may apply the thresholds, such that the output signal 32 is already thresholded.
- the sensitivity of the liquid sensor 30 may also be controlled by suitable positioning of the liquid sensor 30 with respect to the liquid handling material(s) 24 of the wound dressing 14 and/or by the thickness of the cover 16 in reducing the sensing field of the sensor 30 .
- the sensor 30 may be sufficiently insensitive to liquid amounts below the threshold THR-off. Such an arrangement may be especially suitable when water-gelling material is used as the liquid handling material 24 .
- the aspiration system 10 as described herein provides significant advantages compared to the prior art, and can address or mitigate many of the drawbacks of the prior art, especially in terms of efficient aspiration of wound exudate, without drying out the wound site 18 , and without requiring frequent changes of the wound dressing 14 to inspect the degree of wetness of the wound site 18 .
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- Orthopedic Medicine & Surgery (AREA)
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- Orthopedics, Nursing, And Contraception (AREA)
- External Artificial Organs (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/738,332 US20100211029A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing liquid other than urine discharged by the human body |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98090807P | 2007-10-18 | 2007-10-18 | |
| PCT/US2008/080505 WO2009052498A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing liquid other than urine and discharged by the human body |
| US12/738,332 US20100211029A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing liquid other than urine discharged by the human body |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US20100211029A1 true US20100211029A1 (en) | 2010-08-19 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US12/738,332 Abandoned US20100211029A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing liquid other than urine discharged by the human body |
| US12/738,348 Active 2029-11-08 US8303554B2 (en) | 2007-10-18 | 2008-10-20 | Aspiration system and body interface device for removing urine discharged by the human body |
| US12/738,322 Abandoned US20100211032A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing urine discharged by the human body, and liquid sensor therefor |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US12/738,348 Active 2029-11-08 US8303554B2 (en) | 2007-10-18 | 2008-10-20 | Aspiration system and body interface device for removing urine discharged by the human body |
| US12/738,322 Abandoned US20100211032A1 (en) | 2007-10-18 | 2008-10-20 | Aspiration system for removing urine discharged by the human body, and liquid sensor therefor |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20100211029A1 (enExample) |
| EP (3) | EP2244757A4 (enExample) |
| JP (3) | JP2011500225A (enExample) |
| CN (3) | CN101970027B (enExample) |
| AU (3) | AU2008311791A1 (enExample) |
| BR (2) | BRPI0818615A2 (enExample) |
| CA (3) | CA2700372A1 (enExample) |
| MX (3) | MX2010003560A (enExample) |
| NZ (2) | NZ584899A (enExample) |
| WO (3) | WO2009052502A1 (enExample) |
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- 2008-10-20 CN CN200880112571A patent/CN101842123A/zh active Pending
- 2008-10-20 WO PCT/US2008/080510 patent/WO2009052502A1/en not_active Ceased
- 2008-10-20 WO PCT/US2008/080505 patent/WO2009052498A1/en not_active Ceased
- 2008-10-20 BR BRPI0818512A patent/BRPI0818512A2/pt not_active IP Right Cessation
- 2008-10-20 WO PCT/US2008/080503 patent/WO2009052496A1/en not_active Ceased
- 2008-10-20 AU AU2008311795A patent/AU2008311795A1/en not_active Abandoned
- 2008-10-20 MX MX2010003559A patent/MX2010003559A/es not_active Application Discontinuation
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20110060299A1 (en) * | 2008-02-14 | 2011-03-10 | Ichiro Wada | Automatic urine disposal apparatus |
| US20150366715A1 (en) * | 2010-03-15 | 2015-12-24 | Entra Tympanic, LLC. | Device and method for delivering medicine into the tympanic cavity, with sliding assist |
| US9814624B2 (en) * | 2010-03-15 | 2017-11-14 | Entratympanic, Llc | Device and method for delivering medicine into the tympanic cavity, with sliding assist |
| US20110301539A1 (en) * | 2010-06-08 | 2011-12-08 | Rickard Matthew J A | Fill and purge system for a drug reservoir |
| WO2012092948A1 (de) | 2011-01-07 | 2012-07-12 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (Universitätsmedizin) | Absaugvorrichtung |
| US9402937B2 (en) | 2011-01-07 | 2016-08-02 | Georg-August-Universitaet Goettingen Stiftung Oeffentlichen Rechts (Universitaetsmedizin) | Suction device |
| CN107456613A (zh) * | 2017-08-02 | 2017-12-12 | 中国人民解放军第三军医大学第附属医院 | 一种用于促进创面愈合的电场耦合负压便携式治疗装置 |
| US20200383836A1 (en) * | 2017-12-15 | 2020-12-10 | Mölnlycke Health Care Ab | Prophylactic dressing |
| US12161531B2 (en) | 2017-12-15 | 2024-12-10 | Mölnlycke Health Care Ab | Medical dressing |
| US12251293B2 (en) * | 2017-12-15 | 2025-03-18 | Mölnlycke Health Care Ab | Prophylactic dressing |
| US12097040B2 (en) | 2018-06-15 | 2024-09-24 | Coloplast A/S | Wound dressing system and method with data collection based on environmental factor of geographic location |
| US12127848B2 (en) | 2018-06-15 | 2024-10-29 | Coloplast A/S | Wound dressing system, monitor device and related methods |
| US20200289327A1 (en) * | 2019-03-14 | 2020-09-17 | Coloplast A/S | Data collection schemes for a wound dressing and related methods |
| US12453513B2 (en) * | 2019-03-14 | 2025-10-28 | Coloplast A/S | Data collection schemes for a wound dressing and related methods |
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