US20050013855A1 - Cochleate compositions directed against expression of proteins - Google Patents

Cochleate compositions directed against expression of proteins Download PDF

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Publication number
US20050013855A1
US20050013855A1 US10/822,235 US82223504A US2005013855A1 US 20050013855 A1 US20050013855 A1 US 20050013855A1 US 82223504 A US82223504 A US 82223504A US 2005013855 A1 US2005013855 A1 US 2005013855A1
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US
United States
Prior art keywords
sirna
cochleate
morpholino
disease
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/822,235
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English (en)
Inventor
Susan Gould-Fogerite
Raphael Mannino
Patrick Ahl
Gaofeng Shang
Zi Chen
Sara Krause-Elsmore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Medicine and Dentistry of New Jersey
Biodelivery Sciences International Inc
Original Assignee
University of Medicine and Dentistry of New Jersey
Biodelivery Sciences International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/822,235 priority Critical patent/US20050013855A1/en
Application filed by University of Medicine and Dentistry of New Jersey, Biodelivery Sciences International Inc filed Critical University of Medicine and Dentistry of New Jersey
Assigned to UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, BIODELIVERY SCIENCES INTERNATIONAL, INC. reassignment UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GOULD-FOGERITE, SUSAN, AHL, PATRICK, CHEN, ZI WEI, KRAUSE-ELSMORE, SARA L., MANNINO, RAPHAEL J., SHANG, GAOFENG
Publication of US20050013855A1 publication Critical patent/US20050013855A1/en
Priority to PCT/US2005/012026 priority patent/WO2005110361A2/en
Priority to AU2005244262A priority patent/AU2005244262A1/en
Priority to JP2007507542A priority patent/JP2007532573A/ja
Priority to EP05776976A priority patent/EP1737427A2/de
Priority to CA002562499A priority patent/CA2562499A1/en
Priority to US11/578,187 priority patent/US20080242625A1/en
Priority to US11/653,093 priority patent/US20080009457A1/en
Priority to US12/658,636 priority patent/US20110091523A1/en
Priority to US13/298,902 priority patent/US8546555B2/en
Priority to US13/424,282 priority patent/US20120178793A1/en
Priority to US14/038,810 priority patent/US9259392B2/en
Abandoned legal-status Critical Current

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A—HUMAN NECESSITIES
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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Priority Applications (12)

Application Number Priority Date Filing Date Title
US10/822,235 US20050013855A1 (en) 2003-04-09 2004-04-09 Cochleate compositions directed against expression of proteins
PCT/US2005/012026 WO2005110361A2 (en) 2004-04-09 2005-04-11 Nucleotide-cochleate compositions and methods of use
AU2005244262A AU2005244262A1 (en) 2004-04-09 2005-04-11 Nucleotide-cochleate compositions and methods of use
JP2007507542A JP2007532573A (ja) 2004-04-09 2005-04-11 ヌクレオチド−渦巻状組成物および使用の方法
EP05776976A EP1737427A2 (de) 2004-04-09 2005-04-11 Nukleotid-cochleat-zusammensetzungen und anwendungsverfahren
CA002562499A CA2562499A1 (en) 2004-04-09 2005-04-11 Nucleotide-cochleate compositions and methods of use
US11/578,187 US20080242625A1 (en) 2003-04-09 2005-04-11 Nucleotide-Cochleate Compositions And Methods Of Use
US11/653,093 US20080009457A1 (en) 2003-04-09 2007-01-11 Cochleate compositions directed against expression of proteins
US12/658,636 US20110091523A1 (en) 2003-04-09 2010-02-11 Cochleate compositions directed against expression of proteins
US13/298,902 US8546555B2 (en) 2003-04-09 2011-11-17 Cochleate compositions directed against expression of proteins
US13/424,282 US20120178793A1 (en) 2004-04-09 2012-03-19 Nucleotide-cochleate compositions and methods of use
US14/038,810 US9259392B2 (en) 2003-04-09 2013-09-27 Cochleate compositions directed against expression of proteins

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US46307603P 2003-04-15 2003-04-15
US49924703P 2003-08-28 2003-08-28
US50255703P 2003-09-11 2003-09-11
US53275503P 2003-12-24 2003-12-24
US10/822,235 US20050013855A1 (en) 2003-04-09 2004-04-09 Cochleate compositions directed against expression of proteins

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PCT/US2005/012026 Continuation WO2005110361A2 (en) 2003-04-09 2005-04-11 Nucleotide-cochleate compositions and methods of use
US11/578,187 Continuation US20080242625A1 (en) 2003-04-09 2005-04-11 Nucleotide-Cochleate Compositions And Methods Of Use
US11/653,093 Continuation US20080009457A1 (en) 2003-04-09 2007-01-11 Cochleate compositions directed against expression of proteins
US57818708A Continuation 2004-04-09 2008-01-24

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US11/578,187 Abandoned US20080242625A1 (en) 2003-04-09 2005-04-11 Nucleotide-Cochleate Compositions And Methods Of Use
US11/653,093 Abandoned US20080009457A1 (en) 2003-04-09 2007-01-11 Cochleate compositions directed against expression of proteins
US12/658,636 Abandoned US20110091523A1 (en) 2003-04-09 2010-02-11 Cochleate compositions directed against expression of proteins
US13/298,902 Expired - Lifetime US8546555B2 (en) 2003-04-09 2011-11-17 Cochleate compositions directed against expression of proteins
US14/038,810 Expired - Lifetime US9259392B2 (en) 2003-04-09 2013-09-27 Cochleate compositions directed against expression of proteins

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US11/653,093 Abandoned US20080009457A1 (en) 2003-04-09 2007-01-11 Cochleate compositions directed against expression of proteins
US12/658,636 Abandoned US20110091523A1 (en) 2003-04-09 2010-02-11 Cochleate compositions directed against expression of proteins
US13/298,902 Expired - Lifetime US8546555B2 (en) 2003-04-09 2011-11-17 Cochleate compositions directed against expression of proteins
US14/038,810 Expired - Lifetime US9259392B2 (en) 2003-04-09 2013-09-27 Cochleate compositions directed against expression of proteins

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US (6) US20050013855A1 (de)
EP (1) EP1631669A2 (de)
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US9259392B2 (en) 2003-04-09 2016-02-16 Rutgers, The State University Of New Jersey Cochleate compositions directed against expression of proteins
US10792250B2 (en) 2010-12-10 2020-10-06 Ns Technologies Pty Ltd Methods for forming miniemulsions and use thereof for delivering bioactive agents
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US9259392B2 (en) 2003-04-09 2016-02-16 Rutgers, The State University Of New Jersey Cochleate compositions directed against expression of proteins
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EP2421880A1 (de) * 2008-11-26 2012-02-29 University Of Kansas Zusammensetzungen und methoden zur verabreichung von nukleinsäure
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US10792250B2 (en) 2010-12-10 2020-10-06 Ns Technologies Pty Ltd Methods for forming miniemulsions and use thereof for delivering bioactive agents
WO2012167032A1 (en) * 2011-06-01 2012-12-06 Children's Medical Center Corporation Compositions and methods for treating pain
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US9370572B2 (en) 2012-07-30 2016-06-21 Aquarius Biotechnologies, Inc Cochleates made with soy phosphatidylserine
WO2014022414A1 (en) * 2012-07-30 2014-02-06 Coordinated Program Development, Llc Cochleates made with soy phosphatidylserine
US9775907B2 (en) * 2012-07-30 2017-10-03 Matinas Biopharma Nanotechnologies, Inc. Cochleates made with soy phosphatidylserine
RU2659729C2 (ru) * 2012-07-30 2018-07-03 Матинас Биофарма Нанотекнолоджис, Инк. Кохлеаты, полученные с использованием фосфатидилсерина сои
US10716860B2 (en) 2012-07-30 2020-07-21 Matinas Biopharma Nanotechnologies, Inc. Cochleates made with soy phosphatidylserine
CN105050409A (zh) * 2012-07-30 2015-11-11 水瓶座生物技术有限公司(美国) 使用大豆磷脂酰丝氨酸制备的脂质卷
US20150140074A1 (en) * 2012-07-30 2015-05-21 Rutgers, The State University Of New Jersey Cochleates made with soy phosphatidylserine
US11964019B2 (en) 2012-07-30 2024-04-23 Rutgers, The State University Of New Jersey Cochleates made with soy phosphatidylserine

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JP4789208B2 (ja) 2011-10-12
WO2004091572A2 (en) 2004-10-28
JP2011177175A (ja) 2011-09-15
EP1631669A2 (de) 2006-03-08
JP2010508809A (ja) 2010-03-25
US20080009457A1 (en) 2008-01-10
US20110091523A1 (en) 2011-04-21
US20140186430A1 (en) 2014-07-03
US20080242625A1 (en) 2008-10-02

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