US20030224366A1 - Magnetic glass particles, method for their preparation and uses thereof - Google Patents

Magnetic glass particles, method for their preparation and uses thereof Download PDF

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Publication number
US20030224366A1
US20030224366A1 US10/147,679 US14767902A US2003224366A1 US 20030224366 A1 US20030224366 A1 US 20030224366A1 US 14767902 A US14767902 A US 14767902A US 2003224366 A1 US2003224366 A1 US 2003224366A1
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US
United States
Prior art keywords
magnetic
composition
suspension
procedure
glass particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/147,679
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English (en)
Inventor
Kurt Weindel
Michael Riedling
Albert Geiger
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Roche Diagnostics GmbH
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Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP00110165A external-priority patent/EP1154443A1/en
Priority to EP00110165A priority Critical patent/EP1154443A1/en
Priority to ES00981267T priority patent/ES2256068T3/es
Priority to SK664-2002A priority patent/SK287932B6/sk
Priority to CZ20021608A priority patent/CZ20021608A3/cs
Priority to PL356771A priority patent/PL202358B1/pl
Priority to JP2001537749A priority patent/JP2003514383A/ja
Priority to CA002392009A priority patent/CA2392009C/en
Priority to AT00981267T priority patent/ATE315826T1/de
Priority to DK00981267T priority patent/DK1232502T3/da
Priority to HU0203386A priority patent/HUP0203386A3/hu
Priority to PT00981267T priority patent/PT1232502E/pt
Priority to DE60025529T priority patent/DE60025529T2/de
Priority to PCT/EP2000/011459 priority patent/WO2001037291A1/en
Priority to EP00981267A priority patent/EP1232502B1/en
Priority to US10/147,679 priority patent/US20030224366A1/en
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Assigned to ROCHE MOLECULAR SYSTEMS, INC. reassignment ROCHE MOLECULAR SYSTEMS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GEIGER, ALBERT, RIEDLING, MICHAEL, WEINDEL, KURT
Assigned to ROCHE DIAGNOSTICS GMBH reassignment ROCHE DIAGNOSTICS GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ROCHE MOLECULAR SYSTEMS, INC.
Publication of US20030224366A1 publication Critical patent/US20030224366A1/en
Priority to US11/128,024 priority patent/US8129118B2/en
Priority to JP2006019516A priority patent/JP4361905B2/ja
Priority to CY20061100461T priority patent/CY1105229T1/el
Priority to US13/372,218 priority patent/US20120247150A1/en
Abandoned legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B19/00—Other methods of shaping glass
    • C03B19/10—Forming beads
    • C03B19/1005—Forming solid beads
    • C03B19/106—Forming solid beads by chemical vapour deposition; by liquid phase reaction
    • C03B19/1065—Forming solid beads by chemical vapour deposition; by liquid phase reaction by liquid phase reactions, e.g. by means of a gel phase
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C1/00—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels
    • C03C1/006—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels to produce glass through wet route
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C14/00—Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix
    • C03C14/004—Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix the non-glass component being in the form of particles or flakes
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/089—Glass compositions containing silica with 40% to 90% silica, by weight containing boron
    • C03C3/091—Glass compositions containing silica with 40% to 90% silica, by weight containing boron containing aluminium
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/089—Glass compositions containing silica with 40% to 90% silica, by weight containing boron
    • C03C3/091—Glass compositions containing silica with 40% to 90% silica, by weight containing boron containing aluminium
    • C03C3/093—Glass compositions containing silica with 40% to 90% silica, by weight containing boron containing aluminium containing zinc or zirconium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C26/00—Coating not provided for in groups C23C2/00 - C23C24/00
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C30/00—Coating with metallic material characterised only by the composition of the metallic material, i.e. not characterised by the coating process
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0063—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use in a non-magnetic matrix, e.g. granular solids
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C2214/00—Nature of the non-vitreous component
    • C03C2214/08—Metals
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C2214/00—Nature of the non-vitreous component
    • C03C2214/32—Nature of the non-vitreous component comprising a sol-gel process
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/101—Taqman

Definitions

  • FIGS. 14 a, b Sedimentation behaviour of different MGPs in different suspension media
  • the particles with CERAC pigment do not have fissure, as the magnet pigment (23 nm average particle size) does not cause tension forces in the layer so that no fissures are created during the spray drying process. Furthermore, the small CERAC-particles are also incorporated in the fine content so that there are no non-magnetic particles contained therein. The particles are also substantially smaller than the particles with mica which can be observed in these figures with the same magnification. MGPs with the other magnetic pigments are shown at the same magnification in FIG. 6 to FIG. 10.

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Power Engineering (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Metallurgy (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Plant Pathology (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Glass Melting And Manufacturing (AREA)
  • Soft Magnetic Materials (AREA)
  • Hard Magnetic Materials (AREA)
US10/147,679 1995-06-08 2002-05-16 Magnetic glass particles, method for their preparation and uses thereof Abandoned US20030224366A1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
EP00110165A EP1154443A1 (en) 2000-05-12 2000-05-12 Magnetic glass particles, method for their preparation and uses thereof
PCT/EP2000/011459 WO2001037291A1 (en) 1999-11-17 2000-11-17 Magnetic glass particles, method for their preparation and uses thereof
DE60025529T DE60025529T2 (de) 1999-11-17 2000-11-17 Magnetische glasteilchen, herstellungsverfahren und benutzung
CZ20021608A CZ20021608A3 (cs) 1999-11-17 2000-11-17 Magnetické skleněné částice, metody jejich přípravy a použití
PL356771A PL202358B1 (pl) 1999-11-17 2000-11-17 Sposób wytwarzania kompozycji magnetycznych cząstek szklanych, magnetyczne cząstki szklane, kompozycja magnetycznych cząstek szklanych, zawiesina z magnetycznymi cząstkami szklanymi, probówka z kompozycją lub zawiesiną magnetycznych cząstek szklanych, zestaw części z tą probówką, zastosowanie kompozycji, zawiesiny i zestawu zawierających magnetyczne cząstki szklane, sposób izolowania materiału biologicznego
JP2001537749A JP2003514383A (ja) 1999-11-17 2000-11-17 磁性ガラス粒子、それらの製造方法、及びそれらの使用
CA002392009A CA2392009C (en) 1999-11-17 2000-11-17 Magnetic glass particles, method for their preparation and uses thereof
AT00981267T ATE315826T1 (de) 1999-11-17 2000-11-17 Magnetische glasteilchen, herstellungsverfahren und benutzung
EP00981267A EP1232502B1 (en) 1999-11-17 2000-11-17 Magnetic glass particles, method for their preparation and uses thereof
SK664-2002A SK287932B6 (sk) 1999-11-17 2000-11-17 Magnetic glass particles, method for their preparation and uses thereof
PT00981267T PT1232502E (pt) 1999-11-17 2000-11-17 Particulas de vidro magneticas, metodo para a sua preparacao e suas utilizacoes
ES00981267T ES2256068T3 (es) 1999-11-17 2000-11-17 Particulas de cristal magneticas, metodo para su preparacion y usos de las mismas.
HU0203386A HUP0203386A3 (en) 1999-11-17 2000-11-17 Magnetic glass particles, method for their preparation and uses thereof
DK00981267T DK1232502T3 (da) 1999-11-17 2000-11-17 Magnetiske glaspartikler, fremgangsmåde til deres fremstilling samt anvendelser deraf
US10/147,679 US20030224366A1 (en) 1999-11-17 2002-05-16 Magnetic glass particles, method for their preparation and uses thereof
US11/128,024 US8129118B2 (en) 1995-06-08 2005-05-11 Magnetic glass particles, method for their preparation and uses thereof
JP2006019516A JP4361905B2 (ja) 1999-11-17 2006-01-27 磁性ガラス粒子、それらの製造方法、及びそれらの使用
CY20061100461T CY1105229T1 (el) 1999-11-17 2006-04-03 Μαγνητικα υαλινα σωματιδια, μεθοδος για την παραγωγη τους και η χρηση αυτων
US13/372,218 US20120247150A1 (en) 1995-06-08 2012-02-13 Magnetic Glass Particles, Method for Their Preparation and Uses Thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99122853 1999-11-17
EP00110165A EP1154443A1 (en) 2000-05-12 2000-05-12 Magnetic glass particles, method for their preparation and uses thereof
US10/147,679 US20030224366A1 (en) 1999-11-17 2002-05-16 Magnetic glass particles, method for their preparation and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US11/041,750 Continuation-In-Part US7371830B2 (en) 1995-06-08 2005-01-24 Method for separating biological material from a fluid using magnetic particles

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/128,024 Continuation US8129118B2 (en) 1995-06-08 2005-05-11 Magnetic glass particles, method for their preparation and uses thereof

Publications (1)

Publication Number Publication Date
US20030224366A1 true US20030224366A1 (en) 2003-12-04

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Family Applications (3)

Application Number Title Priority Date Filing Date
US10/147,679 Abandoned US20030224366A1 (en) 1995-06-08 2002-05-16 Magnetic glass particles, method for their preparation and uses thereof
US11/128,024 Expired - Fee Related US8129118B2 (en) 1995-06-08 2005-05-11 Magnetic glass particles, method for their preparation and uses thereof
US13/372,218 Abandoned US20120247150A1 (en) 1995-06-08 2012-02-13 Magnetic Glass Particles, Method for Their Preparation and Uses Thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
US11/128,024 Expired - Fee Related US8129118B2 (en) 1995-06-08 2005-05-11 Magnetic glass particles, method for their preparation and uses thereof
US13/372,218 Abandoned US20120247150A1 (en) 1995-06-08 2012-02-13 Magnetic Glass Particles, Method for Their Preparation and Uses Thereof

Country Status (15)

Country Link
US (3) US20030224366A1 (cs)
EP (1) EP1232502B1 (cs)
JP (2) JP2003514383A (cs)
AT (1) ATE315826T1 (cs)
CA (1) CA2392009C (cs)
CY (1) CY1105229T1 (cs)
CZ (1) CZ20021608A3 (cs)
DE (1) DE60025529T2 (cs)
DK (1) DK1232502T3 (cs)
ES (1) ES2256068T3 (cs)
HU (1) HUP0203386A3 (cs)
PL (1) PL202358B1 (cs)
PT (1) PT1232502E (cs)
SK (1) SK287932B6 (cs)
WO (1) WO2001037291A1 (cs)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040126902A1 (en) * 2002-06-27 2004-07-01 Toyo Boseki Kabushiki Kaisha Magnetic carrier for biological substance, production method thereof and isolation method of biological substance using same
EP1642648A1 (de) 2004-09-30 2006-04-05 Roche Diagnostics GmbH Vorrichtung und Verfahren zum Einstellen einer Temperatur einer Flüssigkeit
US7249521B1 (en) 2005-08-24 2007-07-31 Peter Frasca Method for determining the presence of a magnetically susceptible or magnetic material in a sample
US20090258368A1 (en) * 2008-04-14 2009-10-15 Noonan John M Paramagnetic nucleation nanoparticles
US20100041034A1 (en) * 2008-04-14 2010-02-18 Murante Richard S Method for manipulating samples with magnetic nucleation nanoparticles
US20100062421A1 (en) * 2007-04-25 2010-03-11 Wensheng Xia Compositions, methods, and devices for isolating biological materials
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