UA85066C2 - Способ приготавлевания транс- или цис-диаммонийдихлородигидроксоплатины (iv) и ее применение при получении фармацевтически активных веществ - Google Patents

Способ приготавлевания транс- или цис-диаммонийдихлородигидроксоплатины (iv) и ее применение при получении фармацевтически активных веществ

Info

Publication number
UA85066C2
UA85066C2 UAA200605216A UAA200605216A UA85066C2 UA 85066 C2 UA85066 C2 UA 85066C2 UA A200605216 A UAA200605216 A UA A200605216A UA A200605216 A UAA200605216 A UA A200605216A UA 85066 C2 UA85066 C2 UA 85066C2
Authority
UA
Ukraine
Prior art keywords
cis
trans
diammoniumdichlorodihydroxoplatinum
production
preparation
Prior art date
Application number
UAA200605216A
Other languages
English (en)
Ukrainian (uk)
Inventor
Цозер Б. Салама
Original Assignee
Римзер Арцнаймиттель Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Римзер Арцнаймиттель Аг filed Critical Римзер Арцнаймиттель Аг
Publication of UA85066C2 publication Critical patent/UA85066C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Изобретение относится к способу приготовления транс- или цис-диаммонийдихлородигидроксоплатины (ІV) и ее производных. Предлагается ввести транс- или цис-диаммонийдихлороплатину (II) в реакцию с раствором, который содержит >30 % пероксида при температурах ниже 30°С и полученный таким образом продукт растворить в минеральной кислоте с последующим осаждением щелочным раствором.
UAA200605216A 2003-10-13 2004-10-13 Способ приготавлевания транс- или цис-диаммонийдихлородигидроксоплатины (iv) и ее применение при получении фармацевтически активных веществ UA85066C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03090344A EP1524273B1 (de) 2003-10-13 2003-10-13 Verfahren zur Herstellung von trans- oder cis-Diammoniumdichlorodihydroxoplatin (IV)-Salzen und -Derivaten und ihre Verwendung zur Herstellung von pharmazeutischen Wirkstoffen

Publications (1)

Publication Number Publication Date
UA85066C2 true UA85066C2 (ru) 2008-12-25

Family

ID=34354539

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200605216A UA85066C2 (ru) 2003-10-13 2004-10-13 Способ приготавлевания транс- или цис-диаммонийдихлородигидроксоплатины (iv) и ее применение при получении фармацевтически активных веществ

Country Status (18)

Country Link
US (1) US7687651B2 (ru)
EP (2) EP1524273B1 (ru)
JP (1) JP4887153B2 (ru)
CN (1) CN100526324C (ru)
AT (2) ATE346076T1 (ru)
AU (1) AU2004283125B2 (ru)
BR (1) BRPI0415295A (ru)
CA (1) CA2565096C (ru)
DE (3) DE50305768D1 (ru)
DK (1) DK1678189T3 (ru)
ES (1) ES2284061T3 (ru)
HK (1) HK1097848A1 (ru)
MX (1) MXPA06003843A (ru)
PL (1) PL1678189T3 (ru)
RU (1) RU2345086C2 (ru)
UA (1) UA85066C2 (ru)
WO (1) WO2005040045A2 (ru)
ZA (1) ZA200603018B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1523984T3 (da) * 2003-10-13 2007-03-26 Zoser B Salama Farmaceutisk sammensætning indeholdende oxoplatin og dettes salte
CZ296459B6 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
WO2009156706A1 (en) * 2008-06-27 2009-12-30 University Of Strathclyde Pulmonary drug delivery with vesicles comprising non-ionic surfactants
WO2014100417A1 (en) 2012-12-19 2014-06-26 Blend Therapeutics, Inc. Compounds, compositions, and methods for the treatment of cancers
CN103043635B (zh) * 2012-12-25 2015-04-22 浙江大学 一种抗耐药性的顺铂矿化液及其制备方法和应用
EP4311830A1 (en) * 2022-07-29 2024-01-31 King Faisal Specialist Hospital & Research Centre Cisplatin analogue with potent anti-cancer effects and synthesis thereof
WO2024023197A1 (en) * 2022-07-29 2024-02-01 King Faisal Specialist Hospital & Research Centre Cisplatin analogue with potent anti-cancer and cancer stem cell-targeting effects and synthesis thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1585103A (en) * 1976-04-06 1981-02-25 Rustenburg Platinum Mines Ltd Pharmaceutical compositions containing platinum compounds
IL63658A0 (en) * 1980-09-03 1981-11-30 Johnson Matthey Plc Co-ordination compound of platinum and its preparation
SU1021116A1 (ru) 1981-11-20 1996-11-20 МГУ им. М.В.Ломоносова Способ получения цис-диамминдихлородигидроксоплатины (iy)
SU1137698A1 (ru) * 1983-10-17 1996-09-27 МГУ им. М.В.Ломоносова Способ получения цис-диамминдихлородигидроксоплатины (iy)
DE68918878T2 (de) * 1988-02-02 1995-02-23 Johnson Matthey Inc Pt(IV) Komplexe.
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
RU2086261C1 (ru) * 1994-07-08 1997-08-10 Химический факультет Московского государственного университета им.М.В.Ломоносова Противоопухолевое средство
JPH10251285A (ja) * 1997-03-14 1998-09-22 Ss Pharmaceut Co Ltd 白金（ｉｖ）錯体及びこれを含有する医薬
DK1523984T3 (da) 2003-10-13 2007-03-26 Zoser B Salama Farmaceutisk sammensætning indeholdende oxoplatin og dettes salte

Also Published As

Publication number Publication date
US7687651B2 (en) 2010-03-30
EP1678189A2 (de) 2006-07-12
CA2565096A1 (en) 2005-05-06
ZA200603018B (en) 2007-07-25
AU2004283125B2 (en) 2009-06-25
PL1678189T3 (pl) 2007-08-31
RU2345086C2 (ru) 2009-01-27
AU2004283125A1 (en) 2005-05-06
EP1678189B1 (de) 2007-03-21
EP1524273B1 (de) 2006-11-22
JP2007513066A (ja) 2007-05-24
EP1524273A1 (de) 2005-04-20
CA2565096C (en) 2011-02-22
CN100526324C (zh) 2009-08-12
DK1678189T3 (da) 2007-06-11
CN1867573A (zh) 2006-11-22
RU2006116314A (ru) 2007-11-20
ES2284061T3 (es) 2007-11-01
HK1097848A1 (en) 2007-07-06
ATE346076T1 (de) 2006-12-15
DE112004002485D2 (de) 2006-08-24
WO2005040045A3 (de) 2005-07-07
WO2005040045A2 (de) 2005-05-06
US20070286905A1 (en) 2007-12-13
MXPA06003843A (es) 2007-02-02
DE502004003311D1 (de) 2007-05-03
JP4887153B2 (ja) 2012-02-29
BRPI0415295A (pt) 2006-12-26
DE50305768D1 (de) 2007-01-04
ATE357451T1 (de) 2007-04-15

Similar Documents

Publication Publication Date Title
YU57600A (sh) Derivarti biciklične hidroksaminske kiseline
BR0211028A (pt) Solução aquosa, método para formação de associações de fármaco e polìmero, composições farmacêuticas, método para formação de uma composição farmacêutica e produto
GB0113041D0 (en) Chemical compounds
TNSN05244A1 (en) Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
EP1335661A4 (en) PREPARATION OF MICRO BEADS
YU70901A (sh) Derivati 1,4-benzotiazepin-1,1 dioksida zamenjeni radikalima šećera, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
UA74346C2 (ru) Производные аминодикарбоновых кислот, их применение и лекарственное средство
NZ514888A (en) Novel lipoic acid derivatives, their preparation, and pharmaceutical compositions containing them
ES2181608T1 (es) Procedimiento para la produccion de derivaods de acido hialuronico reticulados de forma multiple.
YU91002A (sh) Derivati acilfenil-karbamida, postupak za njihovu proizvodnju i njihova primena kao leka
GB0013488D0 (en) Chemical compound
GEP20074135B (en) Process for the synthesis of (is)-4,5-dimethoxy-1-(methylaminomethyl)- benzocyclobutane and addition salts thereof, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
EP1281722A4 (en) HYALURONIC ACID GEL, METHOD FOR THE PRODUCTION THEREOF, AND THE MEDICAL MATERIAL CONTAINING GEL
HK1068782A1 (en) Pharmaceutical composition of 2-(4-isobutylphenyl)propionic acid
MXPA04004601A (es) Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos.
YU2003A (sh) Stabilne soli o-acetilsalicilne kiseline sa baznim amino-kiselinama
EA200500833A1 (ru) Получение стерильных водных суспензий, содержащих микронизированные кристаллические активные ингредиенты для ингаляции
UA86399C2 (ru) Применение 2,5 дигидроксибензолсульфоновой кислоты для изготовления лекарства, которые применяют для лечения болезней, зависимых от ангиогенеза
GB2456976A (en) System and process for producing a low suspended solids solution and uses therefore
UA85066C2 (ru) Способ приготавлевания транс- или цис-диаммонийдихлородигидроксоплатины (iv) и ее применение при получении фармацевтически активных веществ
AU2936599A (en) Novel matrix metalloproteinase inhibitors and down-regulators
GB0205688D0 (en) Chemical compounds
MXPA02004441A (es) Derivados de isoxazol como inhibidores de la fosfodiesterasa.
TNSN06233A1 (en) 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, methods for production and use thereof as medicaments
GB0228552D0 (en) Chemical compounds