UA83628C2 - Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток - Google Patents

Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток

Info

Publication number
UA83628C2
UA83628C2 UA20041109654A UA20041109654A UA83628C2 UA 83628 C2 UA83628 C2 UA 83628C2 UA 20041109654 A UA20041109654 A UA 20041109654A UA 20041109654 A UA20041109654 A UA 20041109654A UA 83628 C2 UA83628 C2 UA 83628C2
Authority
UA
Ukraine
Prior art keywords
endothelial
protection
stem cell
epithelial cells
cell transplantation
Prior art date
Application number
UA20041109654A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Гюнтер Айсснер
Эрнст Голлер
Original Assignee
Клиникум Дер Универзитет Регенсбург
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Клиникум Дер Универзитет Регенсбург filed Critical Клиникум Дер Универзитет Регенсбург
Publication of UA83628C2 publication Critical patent/UA83628C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
UA20041109654A 2002-05-31 2003-06-02 Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток UA83628C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38411402P 2002-05-31 2002-05-31
US38743802P 2002-06-11 2002-06-11
PCT/EP2003/005753 WO2003101468A1 (en) 2002-05-31 2003-06-02 Method for the protection of endothelial and epithelial cells during chemotherapy

Publications (1)

Publication Number Publication Date
UA83628C2 true UA83628C2 (ru) 2008-08-11

Family

ID=29715309

Family Applications (1)

Application Number Title Priority Date Filing Date
UA20041109654A UA83628C2 (ru) 2002-05-31 2003-06-02 Способ защиты эндотелиальных и эпителиальных клеток во время трансплантации алогенных стволовых клеток

Country Status (16)

Country Link
EP (1) EP1509235A1 (ja)
JP (1) JP2005527636A (ja)
CN (1) CN1304011C (ja)
AU (1) AU2003238189A1 (ja)
CA (1) CA2487171A1 (ja)
EA (1) EA008213B1 (ja)
HR (1) HRP20041213A2 (ja)
IL (1) IL165353A0 (ja)
IS (1) IS7548A (ja)
MX (1) MXPA04011941A (ja)
NO (1) NO20045655L (ja)
NZ (1) NZ536864A (ja)
PL (1) PL374402A1 (ja)
RS (1) RS102504A (ja)
UA (1) UA83628C2 (ja)
WO (1) WO2003101468A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
JP6069209B2 (ja) * 2010-11-12 2017-02-01 ジェンティウム ソシエタ ア レスポンサビリタ リミタータ 移植片対宿主病（ｇｖｈｄ）の予防および／または治療に使用するためのデフィブロタイド
CN104619857A (zh) 2012-06-22 2015-05-13 真蒂奥姆有限公司 用于测定去纤维蛋白多核苷酸的生物活性的基于优球蛋白的方法
EP3026122A1 (en) * 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998048843A1 (en) * 1997-04-28 1998-11-05 Arsinur Burcoglu Method of treating hiv infection and related secondary infections thereof

Also Published As

Publication number Publication date
NO20045655L (no) 2004-12-27
JP2005527636A (ja) 2005-09-15
HRP20041213A2 (en) 2006-04-30
EA200401448A1 (ru) 2005-06-30
WO2003101468A1 (en) 2003-12-11
MXPA04011941A (es) 2005-07-26
EA008213B1 (ru) 2007-04-27
CA2487171A1 (en) 2003-12-11
PL374402A1 (en) 2005-10-17
IS7548A (is) 2004-11-24
EP1509235A1 (en) 2005-03-02
RS102504A (en) 2006-12-15
NZ536864A (en) 2008-08-29
IL165353A0 (en) 2006-01-15
CN1655801A (zh) 2005-08-17
CN1304011C (zh) 2007-03-14
AU2003238189A1 (en) 2003-12-19

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