RS102504A - Method for the protection of endothelial and epithelial cells during chemotherapy - Google Patents
Method for the protection of endothelial and epithelial cells during chemotherapyInfo
- Publication number
- RS102504A RS102504A YU102504A YUP102504A RS102504A RS 102504 A RS102504 A RS 102504A YU 102504 A YU102504 A YU 102504A YU P102504 A YUP102504 A YU P102504A RS 102504 A RS102504 A RS 102504A
- Authority
- RS
- Serbia
- Prior art keywords
- endothelial
- protection
- epithelial cells
- cells during
- during chemotherapy
- Prior art date
Links
- 238000002512 chemotherapy Methods 0.000 title 1
- 210000002889 endothelial cell Anatomy 0.000 title 1
- 230000003511 endothelial effect Effects 0.000 title 1
- 210000002919 epithelial cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 229940124276 oligodeoxyribonucleotide Drugs 0.000 abstract 2
- 230000001681 protective effect Effects 0.000 abstract 2
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000001861 immunosuppressant effect Effects 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38411402P | 2002-05-31 | 2002-05-31 | |
US38743802P | 2002-06-11 | 2002-06-11 | |
PCT/EP2003/005753 WO2003101468A1 (en) | 2002-05-31 | 2003-06-02 | Method for the protection of endothelial and epithelial cells during chemotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
RS102504A true RS102504A (en) | 2006-12-15 |
Family
ID=29715309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU102504A RS102504A (en) | 2002-05-31 | 2003-06-02 | Method for the protection of endothelial and epithelial cells during chemotherapy |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1509235A1 (ja) |
JP (1) | JP2005527636A (ja) |
CN (1) | CN1304011C (ja) |
AU (1) | AU2003238189A1 (ja) |
CA (1) | CA2487171A1 (ja) |
EA (1) | EA008213B1 (ja) |
HR (1) | HRP20041213A2 (ja) |
IL (1) | IL165353A0 (ja) |
IS (1) | IS7548A (ja) |
MX (1) | MXPA04011941A (ja) |
NO (1) | NO20045655L (ja) |
NZ (1) | NZ536864A (ja) |
PL (1) | PL374402A1 (ja) |
RS (1) | RS102504A (ja) |
UA (1) | UA83628C2 (ja) |
WO (1) | WO2003101468A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20031714A1 (it) * | 2003-09-05 | 2005-03-06 | Gentium Spa | Formazioni ad azione antitumorale. |
DK2637672T3 (en) | 2010-11-12 | 2018-10-22 | Gentium S R L | DEFIBROTID FOR USE IN PROPHYLAXY AND / OR TREATMENT OF GRAPHIC VERSUS HOST DISEASE (GVHD) |
WO2013190582A1 (en) | 2012-06-22 | 2013-12-27 | Gentium S.P.A. | Euglobulin-based method for determining the biological activity of defibrotide |
EP3026122A1 (en) * | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Cellular-based method for determining the potency of defibrotide |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998048843A1 (en) * | 1997-04-28 | 1998-11-05 | Arsinur Burcoglu | Method of treating hiv infection and related secondary infections thereof |
-
2003
- 2003-06-02 EA EA200401448A patent/EA008213B1/ru not_active IP Right Cessation
- 2003-06-02 CA CA002487171A patent/CA2487171A1/en not_active Abandoned
- 2003-06-02 PL PL03374402A patent/PL374402A1/xx not_active Application Discontinuation
- 2003-06-02 WO PCT/EP2003/005753 patent/WO2003101468A1/en active Application Filing
- 2003-06-02 AU AU2003238189A patent/AU2003238189A1/en not_active Abandoned
- 2003-06-02 EP EP03735516A patent/EP1509235A1/en not_active Withdrawn
- 2003-06-02 UA UA20041109654A patent/UA83628C2/ru unknown
- 2003-06-02 RS YU102504A patent/RS102504A/sr unknown
- 2003-06-02 CN CNB038125013A patent/CN1304011C/zh not_active Expired - Fee Related
- 2003-06-02 NZ NZ536864A patent/NZ536864A/en unknown
- 2003-06-02 MX MXPA04011941A patent/MXPA04011941A/es unknown
- 2003-06-02 JP JP2004508823A patent/JP2005527636A/ja active Pending
-
2004
- 2004-11-23 IL IL16535304A patent/IL165353A0/xx unknown
- 2004-11-24 IS IS7548A patent/IS7548A/is unknown
- 2004-12-27 HR HR20041213A patent/HRP20041213A2/xx not_active Application Discontinuation
- 2004-12-27 NO NO20045655A patent/NO20045655L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2003238189A1 (en) | 2003-12-19 |
MXPA04011941A (es) | 2005-07-26 |
UA83628C2 (ru) | 2008-08-11 |
CA2487171A1 (en) | 2003-12-11 |
EA200401448A1 (ru) | 2005-06-30 |
IS7548A (is) | 2004-11-24 |
HRP20041213A2 (en) | 2006-04-30 |
PL374402A1 (en) | 2005-10-17 |
NO20045655L (no) | 2004-12-27 |
EA008213B1 (ru) | 2007-04-27 |
CN1304011C (zh) | 2007-03-14 |
NZ536864A (en) | 2008-08-29 |
EP1509235A1 (en) | 2005-03-02 |
CN1655801A (zh) | 2005-08-17 |
JP2005527636A (ja) | 2005-09-15 |
IL165353A0 (en) | 2006-01-15 |
WO2003101468A1 (en) | 2003-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY138059A (en) | Use of ikb-kinase inhibitors in pain therapy | |
MXPA05013642A (es) | Composicion de un antagonista de vegf y un agente antiproliferativo y su uso para el tratamiento de cancer. | |
IL125282A (en) | Substituted imidazole compounds, process for their preparation, pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating cytokine mediated diseases | |
GEP20033092B (en) | Purine Inhibitors of Cyclin Dependent Kinase 2 and Ik-Aa | |
IL144294A0 (en) | P53 inhibitors and therapeutic use of the same | |
BG106104A (en) | Method for the treatment of diseases related to increased number of neutrophils or neutrophil overactivation | |
UA89035C2 (ru) | Эфиры гидроксамовых кислот и их фармацевтическое применение | |
BG106461A (en) | Methods and use of rapid onset of reactive serotonin inhibitors for treating sexual dysfunction | |
UA41355C2 (uk) | Засіб для лікування нейро-сніду | |
MXPA02011247A (es) | Quimioterapia de combinacion. | |
ATE247709T1 (de) | 3'utr des menschliches prohibitin-gens | |
GB0130677D0 (en) | Medicaments and novel compounds | |
MD2196B2 (ro) | Criptoficine, procedeu de obţinere, compoziţii farmaceutice pe baza acestora, metodă de inhibare a proliferării celulelor mamiferelor şi metodă de atenuare a stării patologice cauzate de hiperproliferarea celulelor mamiferelor | |
GEP20012389B (en) | Benzoxazinone Dopamine D4 Receptor Antagonists, Pharmaceutical Composition Containing the Same and Method for Treatment of Psychosis or Schizophrenia | |
IL132853A (en) | Composition for modulating the human sexual response | |
MXPA04011835A (es) | Tratamiento de combinacion para la depresion y ansiedad. | |
RS102504A (en) | Method for the protection of endothelial and epithelial cells during chemotherapy | |
NO984920D0 (no) | Sammensetninger omfattende en nitroneforbindelse for anvendelse ved behandling av okulµr inflammasjon | |
MY126321A (en) | Use of (alpha)-adrenoreceptor antagonists in the prevention and treatment of cancer. | |
DE60236927D1 (de) | Suchtpraevention in der schmerzbehandlung mit gamma vinyl gaba | |
ATE374025T1 (de) | Verbindungen zur beseitigung und/oder linderung der anhedonie | |
MX2022011188A (es) | Derivado biciclico fusionado, metodo de preparacion y uso farmaceutico del mismo. | |
GB0202337D0 (en) | Cancer treatment | |
AU2003281257A8 (en) | A novel use of rapamycin and structural analogues thereof | |
IL136225A0 (en) | Substituted 11-phenyl-dibenzazepine compounds useful for the treatment or prevention of diseases characterized by abnormal cell proliferation |